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The map label for this gene is clpC [H]

Identifier: 86608097

GI number: 86608097

Start: 617632

End: 620106

Strand: Direct

Name: clpC [H]

Synonym: CYB_0607

Alternate gene names: 86608097

Gene position: 617632-620106 (Clockwise)

Preceding gene: 86608096

Following gene: 86608098

Centisome position: 20.27

GC content: 60.93

Gene sequence:

>2475_bases
ATGTTTGAACGCTTTACAGAAAAAGCCATCAAGGTGATCATGCTGGCCCAAGAAGAAGCCAGACGGTTAGGTCACAATTT
CGTTGGCACCGAGCAAATTTTGTTGGGGTTAATCGGCGAGGGCACTGGGGTCGCCGCCAAAGTTCTCAAGTCCATGGGAG
TGAACTTGAAGGACGCCCGCATTGAAGTCGAGAAAATCATCGGTCGGGGATCCGGTTTTGTGGCCGTCGAGATCCCTTTC
ACTCCCCGCGCCAAGCGAGTGCTGGAACTCTCCCTAGAAGAGGCCCGCCAGCTCGGCCACAACTACATCGGCACTGAGCA
CCTGCTCCTGGGACTAATCCGAGAAGGGGAAGGGGTGGCAGCCCGCGTTTTGGAAAACCTGGGGGTGGATCTGTCCAAGG
TGCGCACCCAGGTGATCCGCATGTTGGGCGAGACTGCCGAAGTGACGGCAGGGGGGGGATCCTCCAGCCGCACCAAAACG
CCCACCCTGGACGAATTCGGCTCCAACCTCACCCAACTGGCCCAGGAGGGCAAGCTGGATCCGGTGGTCGGTCGGACGCG
GGAGATCGAGCGGGTGATCCAGATCTTGGGCCGCCGCACCAAGAACAACCCCGTCCTCATTGGCGAGCCGGGGGTAGGCA
AAACCGCCATCGCCGAGGGTTTGGCCCAGCGCATCGTGCAGGGGGATGTGCCGGATATTTTGGCCGACAAGCGGGTGATC
AGCCTGGATATTGGTTTGCTGGTGGCCGGCACCAAGTACCGCGGCGAGTTTGAAGAGCGCCTCAAGAAAATCATGGATGA
GATCCGCAATGCCGGCAACATCATCCTGGTCATCGACGAGGTGCATACCCTGATCGGGGCCGGGGCTGCGGAAGGGGCGA
TTGATGCCGCCAACATCCTCAAGCCTGCTTTGGCCCGCGGCGAGCTGCAGTGCATCGGCGCCACCACCCTGGATGAGTAC
CGCAAGCACATCGAGCGGGATGCTGCTCTGGAGCGCCGCTTCCAGCCCATCATGGTGGGCGAGCCGACGGTCTCCGAGAC
CATCGAGATCCTGTTTGGCTTGCGGGAGCGCTACGAGCAGCACCACAAGCTGAAGATCTCCGATGCCGCCTTGGATGCGG
CAGCCAAGCTGGCCGACCAGTACATCTCCGACCGGTTCTTGCCAGATAAGGCCATCGATTTGATCGACGAGGCTGCTTCG
CGGGTGCGCCTGATCAACTCTCAACTGCCCCCGGCGGCCCGGGAGCTGGATCAAGAGTTGCGGCGAGTGCTCAAGGAGAA
AGACGCTGCGGTGCGGGCCCAGAACTTCGACAAGGCTGGTGAGCTGCGGGATCGGGAGATGGAGATCAAGCAGCAGATCC
GCGCCATTGCCGCTGCCAAAAAAGCCGAGGAGAGCAGCCGCAGCGAAATGCCTGAGGTAACCGAAGAGGACGTGGCCCAA
GTGGTCAGCGCCTGGACGGGGGTGCCGGTGGCCAAGCTGACCGAGAGCGAGTCAGTGAAGCTGCTGAACATGGAAGAAAC
CCTGCACCAGCGCATCATCGGCCAAGACGAAGCGGTGCGGGCCATCTCCCGGGCCATCCGCCGCGCTCGGGTGGGGCTGA
AAAATCCCAACCGCCCCATCGCCAGCTTCATCTTCTCCGGCCCAACAGGGGTGGGCAAAACCGAGCTGACCAAGGCTTTG
GCAGCCTACTTCTTCGGCTCCGAGTCGGCCATGATCCGCCTCGACATGTCGGAATACATGGAGCGGCACACGGTCAGCAA
GCTGATCGGATCCCCGCCGGGCTATGTGGGCTACAACGAGGGGGGTCAGCTCACAGAAGCGGTGCGGCGTCGCCCCTACA
CGGTGGTGCTTTTCGATGAGATCGAGAAGGCGCACCCGGATGTGTTTAACCTATTGCTGCAAATCCTGGAGGATGGCCGC
CTGACCGATGCCAAAGGCCGCACGGTGGACTTCAAGAACACCCTGATCGTGATGACCTCTAACATCGGCTCGAAGGTCAT
CGAGAAGGGCGGCGGTAGCCTCGGCTTCGAGTTCAACACCAACGACGAGGATGCCAACTACAACCGCATCCGCAACCTGG
TGAACGAGGAGCTGAAGCAGTACTTCCGTCCGGAGTTCCTCAACCGCGTGGACGAGATCATCGTCTTCCGGCAACTGACC
AAGGATGAGGTGAAGCAGATTGCCGACATCCTGCTCAAGGAAGTGTTTGACCGCATGACGGAGAAGAAAATCCGCCTTAC
GGTCAGCGACCGCTTCAAAGACTTGGTGGTGGAGGAGGGGTATAACCCCAGCTACGGGGCACGCCCGCTGCGCCGCGCCA
TCCAACGCCTGCTGGAAGACATCCTGGCGGAAGAGATCCTGACTGGGCATGTCCGGGAGGGATCGGAGGTGCTCATCGAT
GTGGATGAGGAGCGCAAGCCCAAGGTGCTGGTCACGGAGCCGGAGCGGGTTCTCTTGCCTCAAGGGGCGGAGTAA

Upstream 100 bases:

>100_bases
TCCGTCTGGGGTATTTACCGTCCCTTGGTTTCGCCAGAACTTGTGCTAGGATTACCCCTATCAAGTCCGCCTTGATGCAG
GCGTAGGGAGCCCGAGGATC

Downstream 100 bases:

>100_bases
AGCTGGCTTTGAGAGGTCCTCAGACTGCAAGGGATCCGTTGGGATGCTGCGGATCCCTTGTGGTCCTCAAGTGTTGTTTT
TCTGGTGTTTTTCAGTTGAA

Product: Clp protease, ATP-binding subunit ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 824; Mature: 824

Protein sequence:

>824_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDARIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLSKVRTQVIRMLGETAEVTAGGGSSSRTKT
PTLDEFGSNLTQLAQEGKLDPVVGRTREIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIVQGDVPDILADKRVI
SLDIGLLVAGTKYRGEFEERLKKIMDEIRNAGNIILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEY
RKHIERDAALERRFQPIMVGEPTVSETIEILFGLRERYEQHHKLKISDAALDAAAKLADQYISDRFLPDKAIDLIDEAAS
RVRLINSQLPPAARELDQELRRVLKEKDAAVRAQNFDKAGELRDREMEIKQQIRAIAAAKKAEESSRSEMPEVTEEDVAQ
VVSAWTGVPVAKLTESESVKLLNMEETLHQRIIGQDEAVRAISRAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKAL
AAYFFGSESAMIRLDMSEYMERHTVSKLIGSPPGYVGYNEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNLLLQILEDGR
LTDAKGRTVDFKNTLIVMTSNIGSKVIEKGGGSLGFEFNTNDEDANYNRIRNLVNEELKQYFRPEFLNRVDEIIVFRQLT
KDEVKQIADILLKEVFDRMTEKKIRLTVSDRFKDLVVEEGYNPSYGARPLRRAIQRLLEDILAEEILTGHVREGSEVLID
VDEERKPKVLVTEPERVLLPQGAE

Sequences:

>Translated_824_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDARIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLSKVRTQVIRMLGETAEVTAGGGSSSRTKT
PTLDEFGSNLTQLAQEGKLDPVVGRTREIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIVQGDVPDILADKRVI
SLDIGLLVAGTKYRGEFEERLKKIMDEIRNAGNIILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEY
RKHIERDAALERRFQPIMVGEPTVSETIEILFGLRERYEQHHKLKISDAALDAAAKLADQYISDRFLPDKAIDLIDEAAS
RVRLINSQLPPAARELDQELRRVLKEKDAAVRAQNFDKAGELRDREMEIKQQIRAIAAAKKAEESSRSEMPEVTEEDVAQ
VVSAWTGVPVAKLTESESVKLLNMEETLHQRIIGQDEAVRAISRAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKAL
AAYFFGSESAMIRLDMSEYMERHTVSKLIGSPPGYVGYNEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNLLLQILEDGR
LTDAKGRTVDFKNTLIVMTSNIGSKVIEKGGGSLGFEFNTNDEDANYNRIRNLVNEELKQYFRPEFLNRVDEIIVFRQLT
KDEVKQIADILLKEVFDRMTEKKIRLTVSDRFKDLVVEEGYNPSYGARPLRRAIQRLLEDILAEEILTGHVREGSEVLID
VDEERKPKVLVTEPERVLLPQGAE
>Mature_824_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDARIEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLSKVRTQVIRMLGETAEVTAGGGSSSRTKT
PTLDEFGSNLTQLAQEGKLDPVVGRTREIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIVQGDVPDILADKRVI
SLDIGLLVAGTKYRGEFEERLKKIMDEIRNAGNIILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEY
RKHIERDAALERRFQPIMVGEPTVSETIEILFGLRERYEQHHKLKISDAALDAAAKLADQYISDRFLPDKAIDLIDEAAS
RVRLINSQLPPAARELDQELRRVLKEKDAAVRAQNFDKAGELRDREMEIKQQIRAIAAAKKAEESSRSEMPEVTEEDVAQ
VVSAWTGVPVAKLTESESVKLLNMEETLHQRIIGQDEAVRAISRAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKAL
AAYFFGSESAMIRLDMSEYMERHTVSKLIGSPPGYVGYNEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNLLLQILEDGR
LTDAKGRTVDFKNTLIVMTSNIGSKVIEKGGGSLGFEFNTNDEDANYNRIRNLVNEELKQYFRPEFLNRVDEIIVFRQLT
KDEVKQIADILLKEVFDRMTEKKIRLTVSDRFKDLVVEEGYNPSYGARPLRRAIQRLLEDILAEEILTGHVREGSEVLID
VDEERKPKVLVTEPERVLLPQGAE

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=334, Percent_Identity=37.4251497005988, Blast_Score=209, Evalue=7e-54,
Organism=Escherichia coli, GI1788943, Length=874, Percent_Identity=46.2242562929062, Blast_Score=741, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=807, Percent_Identity=39.2812887236679, Blast_Score=551, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6320464, Length=722, Percent_Identity=48.3379501385042, Blast_Score=646, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=873, Percent_Identity=36.5406643757159, Blast_Score=537, Evalue=1e-153,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 91653; Mature: 91653

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDAR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHH
IEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGVDLSKVRTQVIRMLGETAEVTAGGGSSSRTKTPTLDEFGSNLTQLAQEGKLD
HHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHCCHHHHHHHCCCCC
PVVGRTREIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIVQGDVPDILADKRVI
CHHCCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCEEE
SLDIGLLVAGTKYRGEFEERLKKIMDEIRNAGNIILVIDEVHTLIGAGAAEGAIDAANIL
EEECCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCHHHHHH
KPALARGELQCIGATTLDEYRKHIERDAALERRFQPIMVGEPTVSETIEILFGLRERYEQ
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHH
HHKLKISDAALDAAAKLADQYISDRFLPDKAIDLIDEAASRVRLINSQLPPAARELDQEL
HCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RRVLKEKDAAVRAQNFDKAGELRDREMEIKQQIRAIAAAKKAEESSRSEMPEVTEEDVAQ
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VVSAWTGVPVAKLTESESVKLLNMEETLHQRIIGQDEAVRAISRAIRRARVGLKNPNRPI
HHHHHCCCCHHHCCCCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHH
ASFIFSGPTGVGKTELTKALAAYFFGSESAMIRLDMSEYMERHTVSKLIGSPPGYVGYNE
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGQLTEAVRRRPYTVVLFDEIEKAHPDVFNLLLQILEDGRLTDAKGRTVDFKNTLIVMTS
CCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCEECCCCCEEECCCEEEEEEC
NIGSKVIEKGGGSLGFEFNTNDEDANYNRIRNLVNEELKQYFRPEFLNRVDEIIVFRQLT
CCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
KDEVKQIADILLKEVFDRMTEKKIRLTVSDRFKDLVVEEGYNPSYGARPLRRAIQRLLED
HHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ILAEEILTGHVREGSEVLIDVDEERKPKVLVTEPERVLLPQGAE
HHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCEEECCCCCC
>Mature Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDAR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHH
IEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGVDLSKVRTQVIRMLGETAEVTAGGGSSSRTKTPTLDEFGSNLTQLAQEGKLD
HHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHCCHHHHHHHCCCCC
PVVGRTREIERVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIVQGDVPDILADKRVI
CHHCCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCEEE
SLDIGLLVAGTKYRGEFEERLKKIMDEIRNAGNIILVIDEVHTLIGAGAAEGAIDAANIL
EEECCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCHHHHHH
KPALARGELQCIGATTLDEYRKHIERDAALERRFQPIMVGEPTVSETIEILFGLRERYEQ
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHH
HHKLKISDAALDAAAKLADQYISDRFLPDKAIDLIDEAASRVRLINSQLPPAARELDQEL
HCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RRVLKEKDAAVRAQNFDKAGELRDREMEIKQQIRAIAAAKKAEESSRSEMPEVTEEDVAQ
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VVSAWTGVPVAKLTESESVKLLNMEETLHQRIIGQDEAVRAISRAIRRARVGLKNPNRPI
HHHHHCCCCHHHCCCCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHH
ASFIFSGPTGVGKTELTKALAAYFFGSESAMIRLDMSEYMERHTVSKLIGSPPGYVGYNE
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGQLTEAVRRRPYTVVLFDEIEKAHPDVFNLLLQILEDGRLTDAKGRTVDFKNTLIVMTS
CCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCEECCCCCEEECCCEEEEEEC
NIGSKVIEKGGGSLGFEFNTNDEDANYNRIRNLVNEELKQYFRPEFLNRVDEIIVFRQLT
CCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
KDEVKQIADILLKEVFDRMTEKKIRLTVSDRFKDLVVEEGYNPSYGARPLRRAIQRLLED
HHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ILAEEILTGHVREGSEVLIDVDEERKPKVLVTEPERVLLPQGAE
HHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]