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The map label for this gene is 86361072

Identifier: 86361072

GI number: 86361072

Start: 384118

End: 384786

Strand: Reverse

Name: 86361072

Synonym: RHE_PF00342

Alternate gene names: NA

Gene position: 384786-384118 (Counterclockwise)

Preceding gene: 86361073

Following gene: 86361071

Centisome position: 59.89

GC content: 59.64

Gene sequence:

>669_bases
ATGACGACGTTCCGCCCGAAATACATCACCTTCGATTGCTACGGCACGCTCACCAACTTCCAGATGGCGGAAGCGGCACG
CGATCTCTACGGCGACCAGCTCGACGAACCGCGCATGGCGGAGTTCGTCAAGAATTTCGCCGCCTATCGTCTCGACGAGA
TCATGGGCGCCTGGAAACCCTATGCCGAGGTGGTGCACAACTCGCTCGAGCGCACATGCAAGCGCAACGGCGTGACATTT
CGCGACGAAGCTGCGCAAATCGTTTACGAGCGCGTTCCGACCTGGGGGCCCCATCGCGACGTAGCCGAGGGTCTTGCCAG
GGTTGCCCGGGAAATTCCGCTGGTGATCCTGTCCAATGCCATGGACGCCCAGATCATGTCGAACGTCGAAAAGCTCGGCG
CACCCTTCCACGCGGTCTATACCGCTCAGCAGGCCAATGCTTACAAGCCACGTTTCCAGGCTTTCGAATACATGTTCGAC
ATGCTCGGCTGCGGGCCTGAGGACGTGCTGCACTGCTCGTCTTCCTTCCGCTACGATCTGATGTCGGCGCACGATCTCGG
AATCAAGAACAAGGTCTGGGTCAATCGCGGCCACGAGCCGGCCAATCCCTATTACGGCTATGTCGAAATCGCTGGTATCT
CGGGCTTGCCTGGCGTCGTCGGCCTCTGA

Upstream 100 bases:

>100_bases
ATAGATTCTGCTTCGGATGCCGCCAATTCAGGTAGGCCAGCGATAAAGCGATGCCTATGATTGTGAAACATCCCGGTTCC
AATCATTCAAGGATACGCAG

Downstream 100 bases:

>100_bases
CGGAGACAAGCGGATGCAGTTCCAATCCTACTGGCACGACACGGCCCGCCCTTTTGCCGAGGCGGCCCAAGGTCCTGTCG
AGGGGCATTACGACGTCGCC

Product: dehalogenase protein

Products: (R)-2-hydroxyacid; halide

Alternate protein names: HAD Family Hydrolase; Hydrolase; Haloalkanoic Acid Dehalogenase; Haloacid Dehalogenase; Dehalogenase; 2-Haloacid Dehalogenase; Haloacid Dehalogenase-Like Hydrolase; Haloacid Dehalogenase I; 2-Haloalkanoic Acid Dehalogenase; Haloacid Dehydrogenase; 2-Haloacid Halidohydrolase Type II; HAD-Superfamily Hydrolase; Haloacid Dehalogenase Type II Truncated; 2-Haloacid Halidohydrolase IVa; 2-Haloacid Halidohydrolase IVA; Dehalogenase Protein; HAD Superfamily Haloalkanoic Acid Dehalogenase

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTTFRPKYITFDCYGTLTNFQMAEAARDLYGDQLDEPRMAEFVKNFAAYRLDEIMGAWKPYAEVVHNSLERTCKRNGVTF
RDEAAQIVYERVPTWGPHRDVAEGLARVAREIPLVILSNAMDAQIMSNVEKLGAPFHAVYTAQQANAYKPRFQAFEYMFD
MLGCGPEDVLHCSSSFRYDLMSAHDLGIKNKVWVNRGHEPANPYYGYVEIAGISGLPGVVGL

Sequences:

>Translated_222_residues
MTTFRPKYITFDCYGTLTNFQMAEAARDLYGDQLDEPRMAEFVKNFAAYRLDEIMGAWKPYAEVVHNSLERTCKRNGVTF
RDEAAQIVYERVPTWGPHRDVAEGLARVAREIPLVILSNAMDAQIMSNVEKLGAPFHAVYTAQQANAYKPRFQAFEYMFD
MLGCGPEDVLHCSSSFRYDLMSAHDLGIKNKVWVNRGHEPANPYYGYVEIAGISGLPGVVGL
>Mature_221_residues
TTFRPKYITFDCYGTLTNFQMAEAARDLYGDQLDEPRMAEFVKNFAAYRLDEIMGAWKPYAEVVHNSLERTCKRNGVTFR
DEAAQIVYERVPTWGPHRDVAEGLARVAREIPLVILSNAMDAQIMSNVEKLGAPFHAVYTAQQANAYKPRFQAFEYMFDM
LGCGPEDVLHCSSSFRYDLMSAHDLGIKNKVWVNRGHEPANPYYGYVEIAGISGLPGVVGL

Specific function: Unknown

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.8.1.2

Molecular weight: Translated: 25093; Mature: 24962

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFRPKYITFDCYGTLTNFQMAEAARDLYGDQLDEPRMAEFVKNFAAYRLDEIMGAWKP
CCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCH
YAEVVHNSLERTCKRNGVTFRDEAAQIVYERVPTWGPHRDVAEGLARVAREIPLVILSNA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHCCCC
MDAQIMSNVEKLGAPFHAVYTAQQANAYKPRFQAFEYMFDMLGCGPEDVLHCSSSFRYDL
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHH
MSAHDLGIKNKVWVNRGHEPANPYYGYVEIAGISGLPGVVGL
HHHHCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TTFRPKYITFDCYGTLTNFQMAEAARDLYGDQLDEPRMAEFVKNFAAYRLDEIMGAWKP
CCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCH
YAEVVHNSLERTCKRNGVTFRDEAAQIVYERVPTWGPHRDVAEGLARVAREIPLVILSNA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHCCCC
MDAQIMSNVEKLGAPFHAVYTAQQANAYKPRFQAFEYMFDMLGCGPEDVLHCSSSFRYDL
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHH
MSAHDLGIKNKVWVNRGHEPANPYYGYVEIAGISGLPGVVGL
HHHHCCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-haloacid; H2O

Specific reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA