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The map label for this gene is phoR [H]

Identifier: 86361054

GI number: 86361054

Start: 364570

End: 366963

Strand: Reverse

Name: phoR [H]

Synonym: RHE_PF00324

Alternate gene names: 86361054

Gene position: 366963-364570 (Counterclockwise)

Preceding gene: 86361055

Following gene: 86361053

Centisome position: 57.11

GC content: 60.86

Gene sequence:

>2394_bases
ATGTGGATGAACGGGGGAACGGTCGTGTCCGGCGAACTGCACACAATCTTTGCAATGGATGGCACGTTAGAATGCCCGCA
TGGTGTCGGCGACGACCTTGAGCGACATGGTATCGTGCTGCGCGTTCACTGCGACCGAGCTGAGCTTCACGAATGGGCCG
CCAAGCGACCGCAGCCGGAGCTTATTCTGCTGGACGCCCAGTCGCGGGAGGGAGGTGGTCTCGAAGACTGCCGGCGTCTC
AAAGCAAACCCCCTAACGCGTGATATTCCGATAATCATCATGGTCTCGCCGGAGGGCGAGGAGAGCCGGATCGAAGGGCT
TGCCGGCGGTGCGGTGGATTGCGTTTCCAACCTTGTCTCCGCCGCGGAGCTCGTCGCCCGCATCAAGCGACATATCGAGC
TCGGCGCAGTCCACGCGCGCCTGCAGCGGCGCAACGAACAACTCGACACGGCGCTTGCCAGCATGGGACAAGGCGTCTGC
CTGTTCGACGAGGCCGGTCGGCTGCTGCTTTCAAACGATCGTTATGCCGAGGTCTACGGACTTGATCCCTCCGTCATTCA
TCCGGGACAGTCGCTTGAAGACATCCTCAACCTGAGGCAAAGGGTCGGCGCCGTTCCCGCCACCTCGACCTCGGAATATC
TCGCCTGGGCCGAAGCGACCAATAAGGGCGATACGCCTCGGGATTGGATCAAGGAACTCAAGTCGGGCCAGATCATCCGT
GGCTATCATCAGCGCACGTCGGACGGCGGCTGGGTATCGACCCACGAGGATATCACGCAGGCTTGGCAGGCTGAAAAGGC
CCTTGCGAAGGCGCATGTCCAGGCAGAACGCGCCGAGCAGGAGGCGCGCGCGGCGCACGCGCGTCTTCTGGCGGCTTTCG
AAGTCGTCCCGGAAGGTCTCGTCCTGTTCGACGAGGAAGACCGCTTCGTCCTGTGGAACCAGAGATATGAGCAGCTTTAC
GCCGAAAGTGGCGATATGCTCGTGAAAGGCATGCGCTTCGAAGACCGCCTGCGTGCTGGCCTCGAACGCGGCCAATATCC
GGAAGCAGTCGGGCGCGAAGAGGAATGGCTGGCGGAGAGGCTGGCCCATCATGCAAAGCCCACCAGCAAACACGAGCAGC
GCCTACCCGGAAACCACTGGATACGGATCGAAGAACGCCAGATCTCCGAAGGCGGTAGCGTCGGCATACGTGTCGACATT
ACCGACCTCAAGATGCAGGAGGCGTCGTTCAGGCTGCTGTTCGAGGGCAACCCGATGCCGATGTGGGTTTACGATCATGA
AACGTTGAGGTTTCTCCACGTAAACCAAGCCGCCATCGATCACTATGGTTATCGTCTGGAGCAATTCCTGACGATGCGAC
TATCCGACATCGAGGCGCAGGAAACCAATCCGCCGGAGGCCGTCGTTTTCGATCTCGAGGATACCGCGTCGTCCCGCTCT
TCCCGCCATCTCAAGGGAGATGGTACGGCCATCGAGGTGACCGTCTATTCCACCTGCTTGAACTACAAGGGCAAGGCGGC
ATCGCTGATGGCTGTCGTCGACGTCACCGAGGCCAAGCGCGCCGAAAAGGCATTGCTGCAGCACCGCGACACGCTTGAAG
AGATGGTGCGCTCCCGCACGGTCGAACTGGCGCGGCAGACAGAAGAACTCGAACGGATGCTCGAACAGGAAAAGCAGATC
AACGAATTGCAGCGACAGTTCGTCTCGATGGCGTCGCATGAGTTCCGCACCCCGCTTGCGGTGATCGACGGCGCGGCGCA
ACGGCTCATTCGGCGCAAAGAGGCAGCGACGCCGGAGTTTCTTTGCGAAAAAGCCGATCAGATCCGCAGCTCGGTTTCGC
GCATGCTTGAACTGATGGAAAGCATTCTTGCCGCCGGGCGGCTGGATCATGGCCGGATCACCATCGTGCACAAGCCGTGC
TCGATTGCCGAGATCATCGGAATCTGCAGCGCGCGCCAGGAAAGCATCCGCCGGTCGCATCGTTTTTTACTCGACCTCGA
CCGGCTTCCCCCGACGATCTTCGGCGATCATCCTGCGCTCGACCAGGTCTTCAGCAATCTCTTCTCGAACGCCGTGAAAT
ACGCGCCTGATGCCCCGAACGTCCACGTGACTGGATGGCAGGACGGGACAAGCGTCTGCATCACGGTCCGCGACGAAGGT
ATCGGCATCGACACCGATGACCTCCCGAAGATGTTCCAGCGATATTTTCGCGCCAGAAGCTCCACGGGCATCGCCGGCAC
CGGCATCGGCCTCAACCTCGTCAAGCAGATCATCGAGCTCCACGGCGGCACGATCGAGGTGGCAAGCAGCCGCGGCAACG
GCACGACCTTCACGCTGCGGCTTCCGATCGGCGCAGAGATATTGGATGAACTGCGCGTTGCTGGCGCCCGGTAG

Upstream 100 bases:

>100_bases
CGCATCGCCCGCAACCGTTCTTCAACCATGCAACGCGGAGCACCCTGATGCCGACCTGAGATGAGGGGCGTGTTAACCGG
TACGACTTATAGTCGCGTCC

Downstream 100 bases:

>100_bases
GCGGGACAAAGATCGTCAGTAACGGCGGCCTTCATCCCGCCATTCGCGCAATTCAGCTTGCGTCGTGGACTGACGAGGGA
TGCGCTGCGCCTTAATTTCG

Product: two-component sensor histidine kinase/response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:

>797_residues
MWMNGGTVVSGELHTIFAMDGTLECPHGVGDDLERHGIVLRVHCDRAELHEWAAKRPQPELILLDAQSREGGGLEDCRRL
KANPLTRDIPIIIMVSPEGEESRIEGLAGGAVDCVSNLVSAAELVARIKRHIELGAVHARLQRRNEQLDTALASMGQGVC
LFDEAGRLLLSNDRYAEVYGLDPSVIHPGQSLEDILNLRQRVGAVPATSTSEYLAWAEATNKGDTPRDWIKELKSGQIIR
GYHQRTSDGGWVSTHEDITQAWQAEKALAKAHVQAERAEQEARAAHARLLAAFEVVPEGLVLFDEEDRFVLWNQRYEQLY
AESGDMLVKGMRFEDRLRAGLERGQYPEAVGREEEWLAERLAHHAKPTSKHEQRLPGNHWIRIEERQISEGGSVGIRVDI
TDLKMQEASFRLLFEGNPMPMWVYDHETLRFLHVNQAAIDHYGYRLEQFLTMRLSDIEAQETNPPEAVVFDLEDTASSRS
SRHLKGDGTAIEVTVYSTCLNYKGKAASLMAVVDVTEAKRAEKALLQHRDTLEEMVRSRTVELARQTEELERMLEQEKQI
NELQRQFVSMASHEFRTPLAVIDGAAQRLIRRKEAATPEFLCEKADQIRSSVSRMLELMESILAAGRLDHGRITIVHKPC
SIAEIIGICSARQESIRRSHRFLLDLDRLPPTIFGDHPALDQVFSNLFSNAVKYAPDAPNVHVTGWQDGTSVCITVRDEG
IGIDTDDLPKMFQRYFRARSSTGIAGTGIGLNLVKQIIELHGGTIEVASSRGNGTTFTLRLPIGAEILDELRVAGAR

Sequences:

>Translated_797_residues
MWMNGGTVVSGELHTIFAMDGTLECPHGVGDDLERHGIVLRVHCDRAELHEWAAKRPQPELILLDAQSREGGGLEDCRRL
KANPLTRDIPIIIMVSPEGEESRIEGLAGGAVDCVSNLVSAAELVARIKRHIELGAVHARLQRRNEQLDTALASMGQGVC
LFDEAGRLLLSNDRYAEVYGLDPSVIHPGQSLEDILNLRQRVGAVPATSTSEYLAWAEATNKGDTPRDWIKELKSGQIIR
GYHQRTSDGGWVSTHEDITQAWQAEKALAKAHVQAERAEQEARAAHARLLAAFEVVPEGLVLFDEEDRFVLWNQRYEQLY
AESGDMLVKGMRFEDRLRAGLERGQYPEAVGREEEWLAERLAHHAKPTSKHEQRLPGNHWIRIEERQISEGGSVGIRVDI
TDLKMQEASFRLLFEGNPMPMWVYDHETLRFLHVNQAAIDHYGYRLEQFLTMRLSDIEAQETNPPEAVVFDLEDTASSRS
SRHLKGDGTAIEVTVYSTCLNYKGKAASLMAVVDVTEAKRAEKALLQHRDTLEEMVRSRTVELARQTEELERMLEQEKQI
NELQRQFVSMASHEFRTPLAVIDGAAQRLIRRKEAATPEFLCEKADQIRSSVSRMLELMESILAAGRLDHGRITIVHKPC
SIAEIIGICSARQESIRRSHRFLLDLDRLPPTIFGDHPALDQVFSNLFSNAVKYAPDAPNVHVTGWQDGTSVCITVRDEG
IGIDTDDLPKMFQRYFRARSSTGIAGTGIGLNLVKQIIELHGGTIEVASSRGNGTTFTLRLPIGAEILDELRVAGAR
>Mature_797_residues
MWMNGGTVVSGELHTIFAMDGTLECPHGVGDDLERHGIVLRVHCDRAELHEWAAKRPQPELILLDAQSREGGGLEDCRRL
KANPLTRDIPIIIMVSPEGEESRIEGLAGGAVDCVSNLVSAAELVARIKRHIELGAVHARLQRRNEQLDTALASMGQGVC
LFDEAGRLLLSNDRYAEVYGLDPSVIHPGQSLEDILNLRQRVGAVPATSTSEYLAWAEATNKGDTPRDWIKELKSGQIIR
GYHQRTSDGGWVSTHEDITQAWQAEKALAKAHVQAERAEQEARAAHARLLAAFEVVPEGLVLFDEEDRFVLWNQRYEQLY
AESGDMLVKGMRFEDRLRAGLERGQYPEAVGREEEWLAERLAHHAKPTSKHEQRLPGNHWIRIEERQISEGGSVGIRVDI
TDLKMQEASFRLLFEGNPMPMWVYDHETLRFLHVNQAAIDHYGYRLEQFLTMRLSDIEAQETNPPEAVVFDLEDTASSRS
SRHLKGDGTAIEVTVYSTCLNYKGKAASLMAVVDVTEAKRAEKALLQHRDTLEEMVRSRTVELARQTEELERMLEQEKQI
NELQRQFVSMASHEFRTPLAVIDGAAQRLIRRKEAATPEFLCEKADQIRSSVSRMLELMESILAAGRLDHGRITIVHKPC
SIAEIIGICSARQESIRRSHRFLLDLDRLPPTIFGDHPALDQVFSNLFSNAVKYAPDAPNVHVTGWQDGTSVCITVRDEG
IGIDTDDLPKMFQRYFRARSSTGIAGTGIGLNLVKQIIELHGGTIEVASSRGNGTTFTLRLPIGAEILDELRVAGAR

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=35.0230414746544, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788393, Length=247, Percent_Identity=27.5303643724696, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=28.1124497991968, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=29.7872340425532, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI87081816, Length=269, Percent_Identity=28.2527881040892, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=26, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=27.0042194092827, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=29.6747967479675, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1786600, Length=243, Percent_Identity=24.6913580246914, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1786783, Length=254, Percent_Identity=27.5590551181102, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1789149, Length=261, Percent_Identity=24.1379310344828, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788279, Length=202, Percent_Identity=28.7128712871287, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=26.8, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790551, Length=230, Percent_Identity=26.9565217391304, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=24.6861924686192, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786599, Length=96, Percent_Identity=39.5833333333333, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89176; Mature: 89176

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWMNGGTVVSGELHTIFAMDGTLECPHGVGDDLERHGIVLRVHCDRAELHEWAAKRPQPE
CCCCCCEEEECCEEEEEEECCCCCCCCCCCCCHHHCCEEEEEECCHHHHHHHHHCCCCCC
LILLDAQSREGGGLEDCRRLKANPLTRDIPIIIMVSPEGEESRIEGLAGGAVDCVSNLVS
EEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHH
AAELVARIKRHIELGAVHARLQRRNEQLDTALASMGQGVCLFDEAGRLLLSNDRYAEVYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCCEEEEEC
LDPSVIHPGQSLEDILNLRQRVGAVPATSTSEYLAWAEATNKGDTPRDWIKELKSGQIIR
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHEEHHCCCCCCCHHHHHHHHHCCCEEE
GYHQRTSDGGWVSTHEDITQAWQAEKALAKAHVQAERAEQEARAAHARLLAAFEVVPEGL
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VLFDEEDRFVLWNQRYEQLYAESGDMLVKGMRFEDRLRAGLERGQYPEAVGREEEWLAER
EEECCCCCEEEECHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCCHHCCCCHHHHHHH
LAHHAKPTSKHEQRLPGNHWIRIEERQISEGGSVGIRVDITDLKMQEASFRLLFEGNPMP
HHHCCCCCCHHHHCCCCCCEEEEEHHCCCCCCCEEEEEEEECCEECCCCEEEEECCCCCE
MWVYDHETLRFLHVNQAAIDHYGYRLEQFLTMRLSDIEAQETNPPEAVVFDLEDTASSRS
EEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHCCCCCC
SRHLKGDGTAIEVTVYSTCLNYKGKAASLMAVVDVTEAKRAEKALLQHRDTLEEMVRSRT
CCCCCCCCCEEEEEEEEHHHCCCCCHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VELARQTEELERMLEQEKQINELQRQFVSMASHEFRTPLAVIDGAAQRLIRRKEAATPEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHH
LCEKADQIRSSVSRMLELMESILAAGRLDHGRITIVHKPCSIAEIIGICSARQESIRRSH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
RFLLDLDRLPPTIFGDHPALDQVFSNLFSNAVKYAPDAPNVHVTGWQDGTSVCITVRDEG
HHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEECCC
IGIDTDDLPKMFQRYFRARSSTGIAGTGIGLNLVKQIIELHGGTIEVASSRGNGTTFTLR
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEE
LPIGAEILDELRVAGAR
CCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MWMNGGTVVSGELHTIFAMDGTLECPHGVGDDLERHGIVLRVHCDRAELHEWAAKRPQPE
CCCCCCEEEECCEEEEEEECCCCCCCCCCCCCHHHCCEEEEEECCHHHHHHHHHCCCCCC
LILLDAQSREGGGLEDCRRLKANPLTRDIPIIIMVSPEGEESRIEGLAGGAVDCVSNLVS
EEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHH
AAELVARIKRHIELGAVHARLQRRNEQLDTALASMGQGVCLFDEAGRLLLSNDRYAEVYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCCEEEEEC
LDPSVIHPGQSLEDILNLRQRVGAVPATSTSEYLAWAEATNKGDTPRDWIKELKSGQIIR
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHEEHHCCCCCCCHHHHHHHHHCCCEEE
GYHQRTSDGGWVSTHEDITQAWQAEKALAKAHVQAERAEQEARAAHARLLAAFEVVPEGL
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VLFDEEDRFVLWNQRYEQLYAESGDMLVKGMRFEDRLRAGLERGQYPEAVGREEEWLAER
EEECCCCCEEEECHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCCHHCCCCHHHHHHH
LAHHAKPTSKHEQRLPGNHWIRIEERQISEGGSVGIRVDITDLKMQEASFRLLFEGNPMP
HHHCCCCCCHHHHCCCCCCEEEEEHHCCCCCCCEEEEEEEECCEECCCCEEEEECCCCCE
MWVYDHETLRFLHVNQAAIDHYGYRLEQFLTMRLSDIEAQETNPPEAVVFDLEDTASSRS
EEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHCCCCCC
SRHLKGDGTAIEVTVYSTCLNYKGKAASLMAVVDVTEAKRAEKALLQHRDTLEEMVRSRT
CCCCCCCCCEEEEEEEEHHHCCCCCHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VELARQTEELERMLEQEKQINELQRQFVSMASHEFRTPLAVIDGAAQRLIRRKEAATPEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHH
LCEKADQIRSSVSRMLELMESILAAGRLDHGRITIVHKPCSIAEIIGICSARQESIRRSH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
RFLLDLDRLPPTIFGDHPALDQVFSNLFSNAVKYAPDAPNVHVTGWQDGTSVCITVRDEG
HHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEECCC
IGIDTDDLPKMFQRYFRARSSTGIAGTGIGLNLVKQIIELHGGTIEVASSRGNGTTFTLR
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCEEEEE
LPIGAEILDELRVAGAR
CCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043; 2115874 [H]