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The map label for this gene is tctD [H]

Identifier: 86361041

GI number: 86361041

Start: 350037

End: 350705

Strand: Reverse

Name: tctD [H]

Synonym: RHE_PF00311

Alternate gene names: 86361041

Gene position: 350705-350037 (Counterclockwise)

Preceding gene: 86361044

Following gene: 86361040

Centisome position: 54.58

GC content: 61.29

Gene sequence:

>669_bases
ATGCGACTGCTTGTGGTGGAGGACAACAAGGAACTGGCGGCCTGGCTGGGCAAAGCCCTGCGGCAGGCGCAATATACGAT
CGACATTGCCTATGACGGCGAAGACGCGGAGCATCTGCTCAAGGTGGCGGAATATTCGGCGATGATCCTCGACCTTTCGC
TGCCGAAGCTCGACGGATTGACGCTCCTGAAGCGGCTGAGACAATCAGGCAACAAGCTCCCGGTCATCATCCTGACCGCC
AATGCGAGCCTCGACGGCCGCGTGGCCGGGCTCGACAGCGGCGCCGACGATTACCTCGCCAAGCCCTTCGAAATCGCCGA
ACTCGAAGCCAGGATACGCGCGGTGGTGCGCCGCGGGCAGGACCGGGCCTCGTCGGAAATCACCGTCGGAAACCTGCGTT
TTTCCGGCGGCACGCGGCAGTTCTTCGTCGAGGGCGAGCCGCTGCAATTGACGCCGCGGGAATATGCCGTGCTCGAACAG
CTCGTCATGAAGCTCGGCACTACGGTTTCGAAAGCCGCCCTGTCCGAAAGCGTCTTCGGTTTCGACGATGAGGCGGATCC
GAGCGCCATCGAAATCTATGTCCATAGGCTTCGAAAGAAGCTCGAAGCCAGCTCCGTGCAGATCGCGACGTTGCGCGGCC
TCGGTTATCTCCTCAGACATGTTCAGTAG

Upstream 100 bases:

>100_bases
GAAGGCAGCCCGATGCCGCGAACGGTGGACGCGATCGAATGTTGCCGCCCTTCCATGCGCCTGCTTCCGCGAGCCCCTCC
GCACGTGCTAAGGGGATTGG

Downstream 100 bases:

>100_bases
CGTCTTCAGGAAAACTGGCGCTGCCATGGGTCGGCTCAGCCAGAGCCTCAGGGTGCAGTTGCTTTCCCTGGTGCTGCTGA
CGCTGTTCGGCGCGATCGGC

Product: two-component response regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MRLLVVEDNKELAAWLGKALRQAQYTIDIAYDGEDAEHLLKVAEYSAMILDLSLPKLDGLTLLKRLRQSGNKLPVIILTA
NASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQDRASSEITVGNLRFSGGTRQFFVEGEPLQLTPREYAVLEQ
LVMKLGTTVSKAALSESVFGFDDEADPSAIEIYVHRLRKKLEASSVQIATLRGLGYLLRHVQ

Sequences:

>Translated_222_residues
MRLLVVEDNKELAAWLGKALRQAQYTIDIAYDGEDAEHLLKVAEYSAMILDLSLPKLDGLTLLKRLRQSGNKLPVIILTA
NASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQDRASSEITVGNLRFSGGTRQFFVEGEPLQLTPREYAVLEQ
LVMKLGTTVSKAALSESVFGFDDEADPSAIEIYVHRLRKKLEASSVQIATLRGLGYLLRHVQ
>Mature_222_residues
MRLLVVEDNKELAAWLGKALRQAQYTIDIAYDGEDAEHLLKVAEYSAMILDLSLPKLDGLTLLKRLRQSGNKLPVIILTA
NASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQDRASSEITVGNLRFSGGTRQFFVEGEPLQLTPREYAVLEQ
LVMKLGTTVSKAALSESVFGFDDEADPSAIEIYVHRLRKKLEASSVQIATLRGLGYLLRHVQ

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=43.5779816513761, Blast_Score=182, Evalue=1e-47,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=39.9082568807339, Blast_Score=163, Evalue=7e-42,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=35.3211009174312, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=35.2941176470588, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=36.8181818181818, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=37.0044052863436, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=37.280701754386, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=31.8181818181818, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=30.2222222222222, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=31.5315315315315, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=31.981981981982, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=29.4642857142857, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=26.5486725663717, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1790299, Length=147, Percent_Identity=31.2925170068027, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=32.7102803738318, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=32.2314049586777, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=37.2549019607843, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=88, Percent_Identity=35.2272727272727, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24525; Mature: 24525

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLVVEDNKELAAWLGKALRQAQYTIDIAYDGEDAEHLLKVAEYSAMILDLSLPKLDGL
CEEEEEECCHHHHHHHHHHHHHCEEEEEEEECCCCHHHHHHHHHHHHEEEEECCCCCCHH
TLLKRLRQSGNKLPVIILTANASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQ
HHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHCCC
DRASSEITVGNLRFSGGTRQFFVEGEPLQLTPREYAVLEQLVMKLGTTVSKAALSESVFG
CCCCCCEEEEEEEECCCCEEEEEECCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHHHCC
FDDEADPSAIEIYVHRLRKKLEASSVQIATLRGLGYLLRHVQ
CCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MRLLVVEDNKELAAWLGKALRQAQYTIDIAYDGEDAEHLLKVAEYSAMILDLSLPKLDGL
CEEEEEECCHHHHHHHHHHHHHCEEEEEEEECCCCHHHHHHHHHHHHEEEEECCCCCCHH
TLLKRLRQSGNKLPVIILTANASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQ
HHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHCCC
DRASSEITVGNLRFSGGTRQFFVEGEPLQLTPREYAVLEQLVMKLGTTVSKAALSESVFG
CCCCCCEEEEEEEECCCCEEEEEECCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHHHCC
FDDEADPSAIEIYVHRLRKKLEASSVQIATLRGLGYLLRHVQ
CCCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]