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The map label for this gene is qseC [H]

Identifier: 86361040

GI number: 86361040

Start: 348647

End: 350011

Strand: Reverse

Name: qseC [H]

Synonym: RHE_PF00310

Alternate gene names: 86361040

Gene position: 350011-348647 (Counterclockwise)

Preceding gene: 86361041

Following gene: 86361034

Centisome position: 54.47

GC content: 63.96

Gene sequence:

>1365_bases
ATGGGTCGGCTCAGCCAGAGCCTCAGGGTGCAGTTGCTTTCCCTGGTGCTGCTGACGCTGTTCGGCGCGATCGGCTTCAA
TCTCTACGACAGTTTCTGGTCAGCCGACGCGACGGCAAAGCTGGTGACGGATCGAACGCTTCTCGCGTCCGCCCGCGTCA
TCGCCGAGGCGGTGCGCGTCGACGAGGGCGGCAATGTTCAGGTGGATGTGCCGCCGGCTGCGCTCGAGATGTTTGATACC
GGCTTCGGCGACCGCGTCTTTTACCAGGTCATCACCGCCTGGGGCAATCTGGTGAGTGGCTTTCCCGATCTGCCGCTGCC
GGCCGTCCAGCGCTCCGGCGAGGATCGCGCCTTCCGCGGCGCCGATGTGCGCGTCCTGATGCTCGATCATCCGGTCGTCG
GTCTTCCCAACGACGGCACGATCTCCGTGACCGTCGCCGTGACGCATATCAGCCAATATGCGATGCGAAAACAATTATGG
CTTTCGGATTTTTCGAAGCAGTTCGTGCTGGTCTTCCTTGCAAGCTTGGTGACCATTCTCGGGCTGCAGCGCGGCCTTGC
GCCGGCTTTGAGGCTGCGGGACGCCGTGCGCCGGCGCGGGCGCAATCGTCTCGATCCGTTGCCGCCGGAGATGGTCCAGA
GCGAATTGCGCCCGCTCGTCCATGCGCTGAACGATTACATGGAGCGCGTCCAGAACCAAATGGCCGCACAGCGGCGGTTC
GTATCGAACGCGGCGCATCAGTTGAGGACGCCGCTTGCGCTGATTTCGACGCAGGCGAGTGTGGCGTCCCGAGAAGATGA
TGCGGCCCGCCGCGACGAGGCGCTTGCTGCGCTCCGCGCCAGTACCCGGCAGATTTCGCGCCTCGCCAGCCAGCTTCTCA
CCTTGTCGCGGGCCGAGCCCGGCAGCCGCCGCCCGCGCAGCGATGCGACCGATCTCAGCAAGGCTGCCCGCGAGATCCTG
GAGGCCTATGCCGAAGAGGCGCTCAAGCGCAACATCGATCTCGGTCTGGAGGCGGACCGCTCCGTCATCGTCGAGGGTGA
CGGGACAATGCTGCGCGAAATGCTGGTTAATCTCATCGACAATGCGATCCGCTATAGCAAAGCCGATGGGCGAGTGACCG
TTGCTGTCGGGCAGGAGAACGGCCACGCGGTCGTCACTGTCGAGGACAATGGGCCGGGCATTCCCGAAGGGGAGCGCGAG
CAGGTTTTTGAACGGTTCTATCGGATCATGGGAACCGAAAGCGAAGGGAGCGGTCTCGGGCTTGCGATTGTCCGTGAGGT
CGTCGAAGGCGCTGGAGGTTCGGTTTCGCTGAGCGATGCGAAGGGCGGCGGGCTCGTCGTGACCATTCGAGTTCCGCTTG
CCTGA

Upstream 100 bases:

>100_bases
AAGAAGCTCGAAGCCAGCTCCGTGCAGATCGCGACGTTGCGCGGCCTCGGTTATCTCCTCAGACATGTTCAGTAGCGTCT
TCAGGAAAACTGGCGCTGCC

Downstream 100 bases:

>100_bases
ATGGTCATGCTTGGGCTTGCCCATTCTGTCCGGTTCCCGACCGTGAGGCTGCCCGTAAAAGGCGGGGAGAGGGTGCGGCA
TGGTCCCTTCGCCGCGGGGA

Product: two-component sensor histidine kinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MGRLSQSLRVQLLSLVLLTLFGAIGFNLYDSFWSADATAKLVTDRTLLASARVIAEAVRVDEGGNVQVDVPPAALEMFDT
GFGDRVFYQVITAWGNLVSGFPDLPLPAVQRSGEDRAFRGADVRVLMLDHPVVGLPNDGTISVTVAVTHISQYAMRKQLW
LSDFSKQFVLVFLASLVTILGLQRGLAPALRLRDAVRRRGRNRLDPLPPEMVQSELRPLVHALNDYMERVQNQMAAQRRF
VSNAAHQLRTPLALISTQASVASREDDAARRDEALAALRASTRQISRLASQLLTLSRAEPGSRRPRSDATDLSKAAREIL
EAYAEEALKRNIDLGLEADRSVIVEGDGTMLREMLVNLIDNAIRYSKADGRVTVAVGQENGHAVVTVEDNGPGIPEGERE
QVFERFYRIMGTESEGSGLGLAIVREVVEGAGGSVSLSDAKGGGLVVTIRVPLA

Sequences:

>Translated_454_residues
MGRLSQSLRVQLLSLVLLTLFGAIGFNLYDSFWSADATAKLVTDRTLLASARVIAEAVRVDEGGNVQVDVPPAALEMFDT
GFGDRVFYQVITAWGNLVSGFPDLPLPAVQRSGEDRAFRGADVRVLMLDHPVVGLPNDGTISVTVAVTHISQYAMRKQLW
LSDFSKQFVLVFLASLVTILGLQRGLAPALRLRDAVRRRGRNRLDPLPPEMVQSELRPLVHALNDYMERVQNQMAAQRRF
VSNAAHQLRTPLALISTQASVASREDDAARRDEALAALRASTRQISRLASQLLTLSRAEPGSRRPRSDATDLSKAAREIL
EAYAEEALKRNIDLGLEADRSVIVEGDGTMLREMLVNLIDNAIRYSKADGRVTVAVGQENGHAVVTVEDNGPGIPEGERE
QVFERFYRIMGTESEGSGLGLAIVREVVEGAGGSVSLSDAKGGGLVVTIRVPLA
>Mature_453_residues
GRLSQSLRVQLLSLVLLTLFGAIGFNLYDSFWSADATAKLVTDRTLLASARVIAEAVRVDEGGNVQVDVPPAALEMFDTG
FGDRVFYQVITAWGNLVSGFPDLPLPAVQRSGEDRAFRGADVRVLMLDHPVVGLPNDGTISVTVAVTHISQYAMRKQLWL
SDFSKQFVLVFLASLVTILGLQRGLAPALRLRDAVRRRGRNRLDPLPPEMVQSELRPLVHALNDYMERVQNQMAAQRRFV
SNAAHQLRTPLALISTQASVASREDDAARRDEALAALRASTRQISRLASQLLTLSRAEPGSRRPRSDATDLSKAAREILE
AYAEEALKRNIDLGLEADRSVIVEGDGTMLREMLVNLIDNAIRYSKADGRVTVAVGQENGHAVVTVEDNGPGIPEGEREQ
VFERFYRIMGTESEGSGLGLAIVREVVEGAGGSVSLSDAKGGGLVVTIRVPLA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=281, Percent_Identity=36.2989323843416, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1786783, Length=289, Percent_Identity=30.4498269896194, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=28.2051282051282, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=30.6306306306306, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788279, Length=300, Percent_Identity=27, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790551, Length=276, Percent_Identity=30.7971014492754, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=29.9145299145299, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=25.3968253968254, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI48994928, Length=245, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790861, Length=326, Percent_Identity=29.4478527607362, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=27.8481012658228, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=27.0386266094421, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789808, Length=334, Percent_Identity=28.1437125748503, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787374, Length=288, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI145693157, Length=229, Percent_Identity=25.764192139738, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082128, Length=301, Percent_Identity=24.9169435215947, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787894, Length=244, Percent_Identity=26.6393442622951, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=22.8699551569507, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=228, Percent_Identity=25.8771929824561, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=249, Percent_Identity=25.3012048192771, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49386; Mature: 49255

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLSQSLRVQLLSLVLLTLFGAIGFNLYDSFWSADATAKLVTDRTLLASARVIAEAVRV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
DEGGNVQVDVPPAALEMFDTGFGDRVFYQVITAWGNLVSGFPDLPLPAVQRSGEDRAFRG
CCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCC
ADVRVLMLDHPVVGLPNDGTISVTVAVTHISQYAMRKQLWLSDFSKQFVLVFLASLVTIL
CCEEEEEECCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLQRGLAPALRLRDAVRRRGRNRLDPLPPEMVQSELRPLVHALNDYMERVQNQMAAQRRF
HHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSNAAHQLRTPLALISTQASVASREDDAARRDEALAALRASTRQISRLASQLLTLSRAEP
HHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GSRRPRSDATDLSKAAREILEAYAEEALKRNIDLGLEADRSVIVEGDGTMLREMLVNLID
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
NAIRYSKADGRVTVAVGQENGHAVVTVEDNGPGIPEGEREQVFERFYRIMGTESEGSGLG
HHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCH
LAIVREVVEGAGGSVSLSDAKGGGLVVTIRVPLA
HHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCC
>Mature Secondary Structure 
GRLSQSLRVQLLSLVLLTLFGAIGFNLYDSFWSADATAKLVTDRTLLASARVIAEAVRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
DEGGNVQVDVPPAALEMFDTGFGDRVFYQVITAWGNLVSGFPDLPLPAVQRSGEDRAFRG
CCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCC
ADVRVLMLDHPVVGLPNDGTISVTVAVTHISQYAMRKQLWLSDFSKQFVLVFLASLVTIL
CCEEEEEECCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLQRGLAPALRLRDAVRRRGRNRLDPLPPEMVQSELRPLVHALNDYMERVQNQMAAQRRF
HHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSNAAHQLRTPLALISTQASVASREDDAARRDEALAALRASTRQISRLASQLLTLSRAEP
HHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GSRRPRSDATDLSKAAREILEAYAEEALKRNIDLGLEADRSVIVEGDGTMLREMLVNLID
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
NAIRYSKADGRVTVAVGQENGHAVVTVEDNGPGIPEGEREQVFERFYRIMGTESEGSGLG
HHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCH
LAIVREVVEGAGGSVSLSDAKGGGLVVTIRVPLA
HHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]