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The map label for this gene is appC [H]

Identifier: 86360962

GI number: 86360962

Start: 246252

End: 247373

Strand: Reverse

Name: appC [H]

Synonym: RHE_PF00232

Alternate gene names: 86360962

Gene position: 247373-246252 (Counterclockwise)

Preceding gene: 86360963

Following gene: 86360961

Centisome position: 38.5

GC content: 60.43

Gene sequence:

>1122_bases
ATGGCCGACATCGCCGTTACAAATATTCAGCCGGATCGCGCCGCCGTCGCATCGCAGTGGCAGCTGATCTGGTGGGCCTT
TCGCCGCCACAAGCTGGCCATGGTGGCGCTCGTCGTTACCGTGCTGATGTATGTCGTTGCCTTGGTTCCGGGCTTCTTCG
CCATCAACGATCCAAATTTGCAAAATGCGCGGGCGACCTTTCATCCGCCGCAGAAACTGCATCTGATCGATACCGAGAAC
GGGTTTTCATTCGGTCCGCATTATTATCCGATGAAGCTGACCCGTGATCCGGAAACGCTCGCCGCCATCTTCAAGGAAGA
CACGACGAAGCGCGTCGACGTCCAATTCTTCGGACGCGGCTACGAATATTCCGTTTTTGGCCTGTTCAACACCAACATCC
ATCTGATCGCCTCGCCCGACAAGACCACGCCGCTGCTTCTCTTCGGCGCCGACCGGCTTGGGCGTGATGTTTTCAGCAGG
ACGGTGCAAGGCTCGCAGGTTTCGCTGTCGATCGGCCTCGTCGGCGTCTTCCTGTCGTTGATGCTCGGCATCGTGATCGG
CGGCATCTCCGGATATTACGGTGGCCGCATCGATTTCTTCATGCAGCGTGTAATCGATTTCGTGCTGTCGCTGCCGACGA
TACCGATCTGGCTCGCCATGGCTGCGGCCCTTCCGCAGGATTGGCCGGCGACGCTGCAATACATGATGATCACAATCATC
CTGTCGCTGACCGGCTGGGCCCAGCTTGCCCGCGTCGTTCGTGGTCGTTTCCTGTCATTGCGCACCGAAGAATTCGTCGC
TGCCGCCAGACTGGATGGCGTTCGCGAAGGCCGCATCATCTTTCGCCACATGCTGCCGAGCTTTGCCAGCCACATCATCG
CGTCGATCACGCTCGCAGTGCCGGCGATGATTCTGGCCGAAACCTCTCTTTCCTTCCTGGGGCTCGGGCTGCAGCCGCCG
ACCATTTCCTGGGGCGTGCTGCTGCGCGAGGCCCAGAACATTCGTTCGATCGCCACGGCGCCCTGGCTCTTCCTGCCGGG
CTGCGCCGTCGTGGTCGCCGTCATGGCGCTCAATCTCCTCGGCGACGGTCTGCGCGACGCGGCCGACCCCTACAACAAAT
GA

Upstream 100 bases:

>100_bases
CGTTCTGCTGATCTGCGCGCTGACGCTGATAGGCTCTCTGATCAGCGACATCCTGCTTGCGCTGGTCGATCCCCGCATCC
GGTTGGAATAGGAGCCTGAT

Downstream 100 bases:

>100_bases
GGCCGGCATGACCGACATCGTACCCATTGCCGGCAGGCCGCTTCTTGAGGTGAAGAACCTCACCGTCGAATTCCCGCTGC
GCACCGGCGTCTTTCGCGCC

Product: oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MADIAVTNIQPDRAAVASQWQLIWWAFRRHKLAMVALVVTVLMYVVALVPGFFAINDPNLQNARATFHPPQKLHLIDTEN
GFSFGPHYYPMKLTRDPETLAAIFKEDTTKRVDVQFFGRGYEYSVFGLFNTNIHLIASPDKTTPLLLFGADRLGRDVFSR
TVQGSQVSLSIGLVGVFLSLMLGIVIGGISGYYGGRIDFFMQRVIDFVLSLPTIPIWLAMAAALPQDWPATLQYMMITII
LSLTGWAQLARVVRGRFLSLRTEEFVAAARLDGVREGRIIFRHMLPSFASHIIASITLAVPAMILAETSLSFLGLGLQPP
TISWGVLLREAQNIRSIATAPWLFLPGCAVVVAVMALNLLGDGLRDAADPYNK

Sequences:

>Translated_373_residues
MADIAVTNIQPDRAAVASQWQLIWWAFRRHKLAMVALVVTVLMYVVALVPGFFAINDPNLQNARATFHPPQKLHLIDTEN
GFSFGPHYYPMKLTRDPETLAAIFKEDTTKRVDVQFFGRGYEYSVFGLFNTNIHLIASPDKTTPLLLFGADRLGRDVFSR
TVQGSQVSLSIGLVGVFLSLMLGIVIGGISGYYGGRIDFFMQRVIDFVLSLPTIPIWLAMAAALPQDWPATLQYMMITII
LSLTGWAQLARVVRGRFLSLRTEEFVAAARLDGVREGRIIFRHMLPSFASHIIASITLAVPAMILAETSLSFLGLGLQPP
TISWGVLLREAQNIRSIATAPWLFLPGCAVVVAVMALNLLGDGLRDAADPYNK
>Mature_372_residues
ADIAVTNIQPDRAAVASQWQLIWWAFRRHKLAMVALVVTVLMYVVALVPGFFAINDPNLQNARATFHPPQKLHLIDTENG
FSFGPHYYPMKLTRDPETLAAIFKEDTTKRVDVQFFGRGYEYSVFGLFNTNIHLIASPDKTTPLLLFGADRLGRDVFSRT
VQGSQVSLSIGLVGVFLSLMLGIVIGGISGYYGGRIDFFMQRVIDFVLSLPTIPIWLAMAAALPQDWPATLQYMMITIIL
SLTGWAQLARVVRGRFLSLRTEEFVAAARLDGVREGRIIFRHMLPSFASHIIASITLAVPAMILAETSLSFLGLGLQPPT
ISWGVLLREAQNIRSIATAPWLFLPGCAVVVAVMALNLLGDGLRDAADPYNK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=226, Percent_Identity=38.9380530973451, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787498, Length=251, Percent_Identity=35.0597609561753, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789889, Length=235, Percent_Identity=38.7234042553192, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787760, Length=225, Percent_Identity=35.5555555555556, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788505, Length=354, Percent_Identity=27.1186440677966, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789964, Length=230, Percent_Identity=35.6521739130435, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787549, Length=225, Percent_Identity=32.8888888888889, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 41220; Mature: 41089

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIAVTNIQPDRAAVASQWQLIWWAFRRHKLAMVALVVTVLMYVVALVPGFFAINDPNL
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
QNARATFHPPQKLHLIDTENGFSFGPHYYPMKLTRDPETLAAIFKEDTTKRVDVQFFGRG
CCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCC
YEYSVFGLFNTNIHLIASPDKTTPLLLFGADRLGRDVFSRTVQGSQVSLSIGLVGVFLSL
CEEEEEEEEECCEEEEECCCCCCEEEEECCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
MLGIVIGGISGYYGGRIDFFMQRVIDFVLSLPTIPIWLAMAAALPQDWPATLQYMMITII
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
LSLTGWAQLARVVRGRFLSLRTEEFVAAARLDGVREGRIIFRHMLPSFASHIIASITLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PAMILAETSLSFLGLGLQPPTISWGVLLREAQNIRSIATAPWLFLPGCAVVVAVMALNLL
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHH
GDGLRDAADPYNK
CCHHHHCCCCCCC
>Mature Secondary Structure 
ADIAVTNIQPDRAAVASQWQLIWWAFRRHKLAMVALVVTVLMYVVALVPGFFAINDPNL
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
QNARATFHPPQKLHLIDTENGFSFGPHYYPMKLTRDPETLAAIFKEDTTKRVDVQFFGRG
CCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCC
YEYSVFGLFNTNIHLIASPDKTTPLLLFGADRLGRDVFSRTVQGSQVSLSIGLVGVFLSL
CEEEEEEEEECCEEEEECCCCCCEEEEECCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHH
MLGIVIGGISGYYGGRIDFFMQRVIDFVLSLPTIPIWLAMAAALPQDWPATLQYMMITII
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
LSLTGWAQLARVVRGRFLSLRTEEFVAAARLDGVREGRIIFRHMLPSFASHIIASITLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
PAMILAETSLSFLGLGLQPPTISWGVLLREAQNIRSIATAPWLFLPGCAVVVAVMALNLL
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHH
GDGLRDAADPYNK
CCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]