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The map label for this gene is thuBf

Identifier: 86360936

GI number: 86360936

Start: 215808

End: 216845

Strand: Reverse

Name: thuBf

Synonym: RHE_PF00205

Alternate gene names: 86360936

Gene position: 216845-215808 (Counterclockwise)

Preceding gene: 86360937

Following gene: 86360929

Centisome position: 33.75

GC content: 61.27

Gene sequence:

>1038_bases
ATGCGCTTGATCATTCTCGGTACTGGAGGATGGGCAAATACCCATGCCATGCATTTTTCGGAGATCGCCGGCGTCAAAAT
TGTTGCTGCCGTCGATACGGACGAGGTTCGGCTGCGGGCCTTCGCGCTCAGGCATACTATCCCGCTGACGTTCACGTCGC
TCGATGACGCCCTTGCCTGGGGAGAGTTTGACGCCGTCACCAATGTCACGCCGGATCGCGCGCACTATTCCACGACGATG
AAGTTACTCGCCGCAGGCAAGCATGTCCTCTGCGAGAAGCCGCTGGCGGTCAACTACCGCGAAGCCAAGGAAATGGCCGA
TGCGGCCGCGGCATCCGGCAAGGTCACGATGGTCAACCTGACCTATCGGAACGTGGCGCCGCTGCAAGCCGCGCGCAAGA
TGGTGCTTGACGGGCGTCTCGGCGCGATCCGCCACTTCGAAGCGTCCTATCTGCAGAGCTGGCTGGTCTCGAAGGCCTGG
GGCGACTGGACCAAGGAATCGCAATGGCTCTGGCGACTGTCGACGAAGCACGGCTCCAACGGCGTGCTGGGCGATGTCGG
TATCCACATTCTCGATTTCGCGGTTTTTGCCGCGGGAAGCGACGTCAAGGCGGCGGCATCGCATCTCAAGGTGTTCGACA
AGAGCCCCGGAAACCGCATCGGCGAGTATGATCTCGACGCAAACGACAGTTTCCTGATGATGGCCGAACTCGAAAACGGT
GCCGCCGGCGTCATCCATGCGACGCGCTGGGCGACCGGCCATCTGAACGAACTGCGCCTGCGCCTGCATGGAGACAAGGG
TGCCCTGGAGGTGGTGCACACGCCTGAAGGCTCCACCCTCAGGACCTGTGAAGGCGCAGATGCCGACAAGGCGATCTGGC
GTACGATTGAAGTCAAACCGGTCCTCACGAATTTCCAGCGATTTGCAAACGCCGTGCAAAAGGGGCAGCCGGATGAGCCG
GGCTTCGGCCACGCCGCCAAGCTGCAGTTCGTCCTTGATCACGCCGTGAAGACGGCGGGCGCTTTGACCGATCTTTAG

Upstream 100 bases:

>100_bases
ACAGATGAATGCCGTGGGCACGGGGCCGTTTGGCCCCGCAAGACGCCGCGATGATCTCGCGGCCGCTCACGCTTTGATGG
ATAACGATGAGGACATAAGA

Downstream 100 bases:

>100_bases
GCAAAGACGCTACGGTCATGGGCGGCTTCTGCAGATTGCTCGGCGTCAGATCCGCCGGTTCAGATCGTCCTCGCTCACCC
CGAAGTGGTCGAGGATGATG

Product: myo-inositol 2-dehydrogenase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MRLIILGTGGWANTHAMHFSEIAGVKIVAAVDTDEVRLRAFALRHTIPLTFTSLDDALAWGEFDAVTNVTPDRAHYSTTM
KLLAAGKHVLCEKPLAVNYREAKEMADAAAASGKVTMVNLTYRNVAPLQAARKMVLDGRLGAIRHFEASYLQSWLVSKAW
GDWTKESQWLWRLSTKHGSNGVLGDVGIHILDFAVFAAGSDVKAAASHLKVFDKSPGNRIGEYDLDANDSFLMMAELENG
AAGVIHATRWATGHLNELRLRLHGDKGALEVVHTPEGSTLRTCEGADADKAIWRTIEVKPVLTNFQRFANAVQKGQPDEP
GFGHAAKLQFVLDHAVKTAGALTDL

Sequences:

>Translated_345_residues
MRLIILGTGGWANTHAMHFSEIAGVKIVAAVDTDEVRLRAFALRHTIPLTFTSLDDALAWGEFDAVTNVTPDRAHYSTTM
KLLAAGKHVLCEKPLAVNYREAKEMADAAAASGKVTMVNLTYRNVAPLQAARKMVLDGRLGAIRHFEASYLQSWLVSKAW
GDWTKESQWLWRLSTKHGSNGVLGDVGIHILDFAVFAAGSDVKAAASHLKVFDKSPGNRIGEYDLDANDSFLMMAELENG
AAGVIHATRWATGHLNELRLRLHGDKGALEVVHTPEGSTLRTCEGADADKAIWRTIEVKPVLTNFQRFANAVQKGQPDEP
GFGHAAKLQFVLDHAVKTAGALTDL
>Mature_345_residues
MRLIILGTGGWANTHAMHFSEIAGVKIVAAVDTDEVRLRAFALRHTIPLTFTSLDDALAWGEFDAVTNVTPDRAHYSTTM
KLLAAGKHVLCEKPLAVNYREAKEMADAAAASGKVTMVNLTYRNVAPLQAARKMVLDGRLGAIRHFEASYLQSWLVSKAW
GDWTKESQWLWRLSTKHGSNGVLGDVGIHILDFAVFAAGSDVKAAASHLKVFDKSPGNRIGEYDLDANDSFLMMAELENG
AAGVIHATRWATGHLNELRLRLHGDKGALEVVHTPEGSTLRTCEGADADKAIWRTIEVKPVLTNFQRFANAVQKGQPDEP
GFGHAAKLQFVLDHAVKTAGALTDL

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=248, Percent_Identity=31.0483870967742, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24581117, Length=126, Percent_Identity=31.7460317460317, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37571; Mature: 37571

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIILGTGGWANTHAMHFSEIAGVKIVAAVDTDEVRLRAFALRHTIPLTFTSLDDALAW
CEEEEEECCCCCCCCHHHHHHHCCEEEEEEECCCHHHHHEEHHHHCCCEEEECCHHHHHC
GEFDAVTNVTPDRAHYSTTMKLLAAGKHVLCEKPLAVNYREAKEMADAAAASGKVTMVNL
CCCCHHCCCCCCHHHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHHCCCCEEEEEE
TYRNVAPLQAARKMVLDGRLGAIRHFEASYLQSWLVSKAWGDWTKESQWLWRLSTKHGSN
EECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC
GVLGDVGIHILDFAVFAAGSDVKAAASHLKVFDKSPGNRIGEYDLDANDSFLMMAELENG
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCC
AAGVIHATRWATGHLNELRLRLHGDKGALEVVHTPEGSTLRTCEGADADKAIWRTIEVKP
CEEEEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCEEEECCCCCCCHHHHEEEEEEH
VLTNFQRFANAVQKGQPDEPGFGHAAKLQFVLDHAVKTAGALTDL
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCHHCCC
>Mature Secondary Structure
MRLIILGTGGWANTHAMHFSEIAGVKIVAAVDTDEVRLRAFALRHTIPLTFTSLDDALAW
CEEEEEECCCCCCCCHHHHHHHCCEEEEEEECCCHHHHHEEHHHHCCCEEEECCHHHHHC
GEFDAVTNVTPDRAHYSTTMKLLAAGKHVLCEKPLAVNYREAKEMADAAAASGKVTMVNL
CCCCHHCCCCCCHHHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHHCCCCEEEEEE
TYRNVAPLQAARKMVLDGRLGAIRHFEASYLQSWLVSKAWGDWTKESQWLWRLSTKHGSN
EECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC
GVLGDVGIHILDFAVFAAGSDVKAAASHLKVFDKSPGNRIGEYDLDANDSFLMMAELENG
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCC
AAGVIHATRWATGHLNELRLRLHGDKGALEVVHTPEGSTLRTCEGADADKAIWRTIEVKP
CEEEEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCEEEECCCCCCCHHHHEEEEEEH
VLTNFQRFANAVQKGQPDEPGFGHAAKLQFVLDHAVKTAGALTDL
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]