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The map label for this gene is dinB

Identifier: 86360880

GI number: 86360880

Start: 157052

End: 158143

Strand: Reverse

Name: dinB

Synonym: RHE_PF00149

Alternate gene names: 86360880

Gene position: 158143-157052 (Counterclockwise)

Preceding gene: 86360886

Following gene: 86360878

Centisome position: 24.61

GC content: 60.53

Gene sequence:

>1092_bases
ATGACAAATGATGAAGGTCTCGAGCGGCCGCGCAAGATCATCCATATAGATATGGATGCCTATTACGCGTCGGTTGAGCA
GCGCGATAATCCGGAATTACGCGGCAAGCCGATTGCCGTCGGTGGATCAGCCGCCCGCGGCGTGGTGGCGGCGGCGAGCT
ATGAGGCGCGCAAATTCGGCGTGCACTCTGCGATGCCGTCGGTCACCGCGAAACGGAAGTGCCCCGACCTCATCTTCGTG
CCACCGCGCTTCGATATCTACAAGGCGGTGTCGCAGCAGATCCGCGAAATCTTCGCCGAATACACGCCAATGATCGAGCC
GTTGTCACTCGATGAGGCCTATCTCGATGTCACGCACAATCTCAAAGGCATGGAAATCGCCACCGAAATTGCGCTGGAGA
TCCGCGCTAGGATCAAAGCGATCACCGGCCTCAACGCCTCGGCCGGCATCTCCTACAACAAGTTCCTCGCCAAGATGGCG
AGCGATCTCAACAAGCCCAACGGCCAAGCGGTCATTACGCCGCGCAATGGGCCGGCTTTCGTCGAGGCCCTTCCCGTCAA
GAAATTCCATGGCGTCGGCCCGGCGACGGCGGAAAAGATGCACCGGCTTGGAATCGATACCGGCGCCGACCTCAAGGGAA
AGACGCTCGAATTCCTGGTCGAGCATTTCGGGAAGTCCGGTCCCTATTTTTACGGCATTGCCCGCGGCATCGATGAGCGC
CAGGTCAAGCCGAACCGGGTGCGCAAATCCGTCGGCGCCGAAGATACCTTCTCGCAGGACCTCCACGCTTACGAGCCGGC
CCGCGAGGCGCTTCAGCCGCTGATCGAAAAGGTGTGGGGTTATTGCGAGGCCAATGGGATCGGCGCCAAGACGGTGATGC
TCAAGGTCAAATATGCCGATTTCAACCAGATCACCCGCAGCAAGACCGTTCCCATTCCTCTGGCCGCGATCGCCGATCTG
GAGGAGATCGTGGGCCTGCTGCTGGCGCCGATCTTTCCGCCCCGAAAGGGCATTCGCCTGCTTGGCGTCTCGCTGTCGTC
GCTCGAAAGGCGCGCCGCCGGAACGGAACCGCAACTGCGGTTGGCGCTTTAG

Upstream 100 bases:

>100_bases
GGCGGATGGCCATGGGCTGCGAGCGCATGCAAACGCCGGACAAATGCGGCGCGCGCTTCCCATGTCTGGGGGACACAGAT
GGTCCTGATGGAAGCCAGTC

Downstream 100 bases:

>100_bases
ATCGCGAGCATCGGCTGGGCAGGCTCGCAGGCGCGGCGCTTGACCCGGAAGGTGCCCGCCGGCAGCGGCCGCAGGATTTC
CTCTTCGGGGACAACTCCAT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 2 [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTNDEGLERPRKIIHIDMDAYYASVEQRDNPELRGKPIAVGGSAARGVVAAASYEARKFGVHSAMPSVTAKRKCPDLIFV
PPRFDIYKAVSQQIREIFAEYTPMIEPLSLDEAYLDVTHNLKGMEIATEIALEIRARIKAITGLNASAGISYNKFLAKMA
SDLNKPNGQAVITPRNGPAFVEALPVKKFHGVGPATAEKMHRLGIDTGADLKGKTLEFLVEHFGKSGPYFYGIARGIDER
QVKPNRVRKSVGAEDTFSQDLHAYEPAREALQPLIEKVWGYCEANGIGAKTVMLKVKYADFNQITRSKTVPIPLAAIADL
EEIVGLLLAPIFPPRKGIRLLGVSLSSLERRAAGTEPQLRLAL

Sequences:

>Translated_363_residues
MTNDEGLERPRKIIHIDMDAYYASVEQRDNPELRGKPIAVGGSAARGVVAAASYEARKFGVHSAMPSVTAKRKCPDLIFV
PPRFDIYKAVSQQIREIFAEYTPMIEPLSLDEAYLDVTHNLKGMEIATEIALEIRARIKAITGLNASAGISYNKFLAKMA
SDLNKPNGQAVITPRNGPAFVEALPVKKFHGVGPATAEKMHRLGIDTGADLKGKTLEFLVEHFGKSGPYFYGIARGIDER
QVKPNRVRKSVGAEDTFSQDLHAYEPAREALQPLIEKVWGYCEANGIGAKTVMLKVKYADFNQITRSKTVPIPLAAIADL
EEIVGLLLAPIFPPRKGIRLLGVSLSSLERRAAGTEPQLRLAL
>Mature_362_residues
TNDEGLERPRKIIHIDMDAYYASVEQRDNPELRGKPIAVGGSAARGVVAAASYEARKFGVHSAMPSVTAKRKCPDLIFVP
PRFDIYKAVSQQIREIFAEYTPMIEPLSLDEAYLDVTHNLKGMEIATEIALEIRARIKAITGLNASAGISYNKFLAKMAS
DLNKPNGQAVITPRNGPAFVEALPVKKFHGVGPATAEKMHRLGIDTGADLKGKTLEFLVEHFGKSGPYFYGIARGIDERQ
VKPNRVRKSVGAEDTFSQDLHAYEPAREALQPLIEKVWGYCEANGIGAKTVMLKVKYADFNQITRSKTVPIPLAAIADLE
EIVGLLLAPIFPPRKGIRLLGVSLSSLERRAAGTEPQLRLAL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=348, Percent_Identity=33.0459770114943, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI84043967, Length=347, Percent_Identity=31.9884726224784, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI5729982, Length=320, Percent_Identity=31.5625, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI7705344, Length=120, Percent_Identity=54.1666666666667, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI154350220, Length=352, Percent_Identity=29.8295454545455, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1786425, Length=305, Percent_Identity=49.1803278688525, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1787432, Length=218, Percent_Identity=31.1926605504587, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI193205700, Length=400, Percent_Identity=33.25, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17537959, Length=263, Percent_Identity=32.319391634981, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193205702, Length=349, Percent_Identity=29.2263610315186, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115534089, Length=139, Percent_Identity=39.568345323741, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19923006, Length=304, Percent_Identity=30.5921052631579, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI21355641, Length=310, Percent_Identity=30.3225806451613, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24644984, Length=310, Percent_Identity=30.3225806451613, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24668444, Length=251, Percent_Identity=27.8884462151394, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39790; Mature: 39658

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDEGLERPRKIIHIDMDAYYASVEQRDNPELRGKPIAVGGSAARGVVAAASYEARKFG
CCCCHHHHCCCEEEEEEHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEECCCHHHHHHH
VHSAMPSVTAKRKCPDLIFVPPRFDIYKAVSQQIREIFAEYTPMIEPLSLDEAYLDVTHN
HHHHCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCC
LKGMEIATEIALEIRARIKAITGLNASAGISYNKFLAKMASDLNKPNGQAVITPRNGPAF
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCE
VEALPVKKFHGVGPATAEKMHRLGIDTGADLKGKTLEFLVEHFGKSGPYFYGIARGIDER
EEEECHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEHHHCCCCCC
QVKPNRVRKSVGAEDTFSQDLHAYEPAREALQPLIEKVWGYCEANGIGAKTVMLKVKYAD
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECC
FNQITRSKTVPIPLAAIADLEEIVGLLLAPIFPPRKGIRLLGVSLSSLERRAAGTEPQLR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHCCCCCCEE
LAL
ECC
>Mature Secondary Structure 
TNDEGLERPRKIIHIDMDAYYASVEQRDNPELRGKPIAVGGSAARGVVAAASYEARKFG
CCCHHHHCCCEEEEEEHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEECCCHHHHHHH
VHSAMPSVTAKRKCPDLIFVPPRFDIYKAVSQQIREIFAEYTPMIEPLSLDEAYLDVTHN
HHHHCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCC
LKGMEIATEIALEIRARIKAITGLNASAGISYNKFLAKMASDLNKPNGQAVITPRNGPAF
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCE
VEALPVKKFHGVGPATAEKMHRLGIDTGADLKGKTLEFLVEHFGKSGPYFYGIARGIDER
EEEECHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEHHHCCCCCC
QVKPNRVRKSVGAEDTFSQDLHAYEPAREALQPLIEKVWGYCEANGIGAKTVMLKVKYAD
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECC
FNQITRSKTVPIPLAAIADLEEIVGLLLAPIFPPRKGIRLLGVSLSSLERRAAGTEPQLR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHCCCCCCEE
LAL
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]