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The map label for this gene is fabG [H]

Identifier: 86360742

GI number: 86360742

Start: 8493

End: 9152

Strand: Reverse

Name: fabG [H]

Synonym: RHE_PF00008

Alternate gene names: 86360742

Gene position: 9152-8493 (Counterclockwise)

Preceding gene: 86360745

Following gene: 86360741

Centisome position: 1.42

GC content: 65.61

Gene sequence:

>660_bases
ATGGGCGCTGCAGCCGCAAGGAGGCTTGCAGCGGACGGCTATCGCGTCGCCGTTCTCTCCTCCTCCGGCAAGGGAGAGGC
GCTGGCCGACGAACTCGGCGGCGTCGGCGTCACCGGCTCGAACCAGTCGAATGACGACCTGAAGCGACTCGTCGCTCTGG
CGATGGAAAGATGGGGCCGGATCGATGCGCTGGTCAATTCCGCCGGTCACGGTCCGCGCGCGCCGATCCTCGAAATTTCG
GATGAGGACTGGCACAAGGGCATGGAGATCTATTTCCTGAGCGCCGTGCGGCCGATCCGGCTGGTGACGCCGATCATGGA
AGCGCAGGGCGGCGGCGCGATCGTCAACATTTCGACGGCATGGGCCTTCGAGCCTTCGCCGATGTTCCCGACGTCGGCGG
TCGCCCGTGCGGGCCTGGCGAGCTTCACCAAGATCTTCGCCGACACTTACGCGCCCAAGAACATCCGCATGAACAACGTC
CTGCCCGGCTGGATCGACAGCCTACCCGCCACCGACGAGCGGCGCGACAGCGTTCCAATGGGCCGTTATGGCACGAGCGA
GGAAATCGCCGCCACTATCGCCTTCCTCCTATCGGAGGGTGCGGGCTACATCACCGGCCAGAACATCCGCGTCGACGGCG
GCATCGCCCGTTCCGTCTGA

Upstream 100 bases:

>100_bases
AGTCCCGCCGGCATCTGTCATAATGCTGTGCAAAATCAGCTATCGGAGGTTCTCAGTGTCTGAAGGAAAAGTCGCTCTCA
TCACCGCCGGCGGGTCCGGC

Downstream 100 bases:

>100_bases
GCGAGGCCTGCCGGTGGATCTCACTGACATCGACGCCTCGGCATGGGCGGAACTCGAAACGGCTGCGGCAGGTCCACGGT
CGGGTTTCCGCTATGTGAAC

Product: oxidoreductase protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MGAAAARRLAADGYRVAVLSSSGKGEALADELGGVGVTGSNQSNDDLKRLVALAMERWGRIDALVNSAGHGPRAPILEIS
DEDWHKGMEIYFLSAVRPIRLVTPIMEAQGGGAIVNISTAWAFEPSPMFPTSAVARAGLASFTKIFADTYAPKNIRMNNV
LPGWIDSLPATDERRDSVPMGRYGTSEEIAATIAFLLSEGAGYITGQNIRVDGGIARSV

Sequences:

>Translated_219_residues
MGAAAARRLAADGYRVAVLSSSGKGEALADELGGVGVTGSNQSNDDLKRLVALAMERWGRIDALVNSAGHGPRAPILEIS
DEDWHKGMEIYFLSAVRPIRLVTPIMEAQGGGAIVNISTAWAFEPSPMFPTSAVARAGLASFTKIFADTYAPKNIRMNNV
LPGWIDSLPATDERRDSVPMGRYGTSEEIAATIAFLLSEGAGYITGQNIRVDGGIARSV
>Mature_218_residues
GAAAARRLAADGYRVAVLSSSGKGEALADELGGVGVTGSNQSNDDLKRLVALAMERWGRIDALVNSAGHGPRAPILEISD
EDWHKGMEIYFLSAVRPIRLVTPIMEAQGGGAIVNISTAWAFEPSPMFPTSAVARAGLASFTKIFADTYAPKNIRMNNVL
PGWIDSLPATDERRDSVPMGRYGTSEEIAATIAFLLSEGAGYITGQNIRVDGGIARSV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=231, Percent_Identity=35.9307359307359, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI126723750, Length=234, Percent_Identity=31.6239316239316, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI40254992, Length=222, Percent_Identity=28.3783783783784, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI5031737, Length=229, Percent_Identity=31.0043668122271, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI19923817, Length=186, Percent_Identity=32.258064516129, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI126723191, Length=165, Percent_Identity=35.7575757575758, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI66933014, Length=170, Percent_Identity=30, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=226, Percent_Identity=29.2035398230088, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI33667109, Length=174, Percent_Identity=32.183908045977, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI15277342, Length=161, Percent_Identity=30.4347826086957, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI7705925, Length=168, Percent_Identity=27.9761904761905, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI302344755, Length=107, Percent_Identity=33.6448598130841, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788459, Length=176, Percent_Identity=35.7954545454545, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787335, Length=225, Percent_Identity=31.5555555555556, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789208, Length=180, Percent_Identity=31.6666666666667, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082160, Length=176, Percent_Identity=28.4090909090909, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87082100, Length=235, Percent_Identity=29.3617021276596, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1787905, Length=180, Percent_Identity=30.5555555555556, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786812, Length=172, Percent_Identity=30.2325581395349, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI2367175, Length=236, Percent_Identity=28.3898305084746, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=235, Percent_Identity=32.3404255319149, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=240, Percent_Identity=31.6666666666667, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=231, Percent_Identity=27.7056277056277, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=245, Percent_Identity=30.6122448979592, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=193, Percent_Identity=31.0880829015544, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=246, Percent_Identity=30.8943089430894, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=228, Percent_Identity=31.5789473684211, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=183, Percent_Identity=28.9617486338798, Blast_Score=73, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=247, Percent_Identity=28.3400809716599, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=252, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=241, Percent_Identity=27.8008298755187, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=194, Percent_Identity=28.8659793814433, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=168, Percent_Identity=27.3809523809524, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=236, Percent_Identity=25.8474576271186, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=254, Percent_Identity=28.3464566929134, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=249, Percent_Identity=27.3092369477912, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=231, Percent_Identity=30.7359307359307, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI23397609, Length=229, Percent_Identity=29.2576419213974, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21357041, Length=186, Percent_Identity=31.7204301075269, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571526, Length=182, Percent_Identity=31.8681318681319, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24639444, Length=234, Percent_Identity=30.3418803418803, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644339, Length=237, Percent_Identity=28.2700421940928, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24644337, Length=193, Percent_Identity=27.979274611399, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 23164; Mature: 23032

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAAAARRLAADGYRVAVLSSSGKGEALADELGGVGVTGSNQSNDDLKRLVALAMERWGR
CCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IDALVNSAGHGPRAPILEISDEDWHKGMEIYFLSAVRPIRLVTPIMEAQGGGAIVNISTA
HHHHHHCCCCCCCCCEEEECCCHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEE
WAFEPSPMFPTSAVARAGLASFTKIFADTYAPKNIRMNNVLPGWIDSLPATDERRDSVPM
EEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHCCCCCCCCCCCCCC
GRYGTSEEIAATIAFLLSEGAGYITGQNIRVDGGIARSV
CCCCCHHHHHHHHHHHHHCCCCEEECCEEEECCCHHCCC
>Mature Secondary Structure 
GAAAARRLAADGYRVAVLSSSGKGEALADELGGVGVTGSNQSNDDLKRLVALAMERWGR
CHHHHHHHHCCCEEEEEEECCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IDALVNSAGHGPRAPILEISDEDWHKGMEIYFLSAVRPIRLVTPIMEAQGGGAIVNISTA
HHHHHHCCCCCCCCCEEEECCCHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEE
WAFEPSPMFPTSAVARAGLASFTKIFADTYAPKNIRMNNVLPGWIDSLPATDERRDSVPM
EEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHCCCCCCCCCCCCCC
GRYGTSEEIAATIAFLLSEGAGYITGQNIRVDGGIARSV
CCCCCHHHHHHHHHHHHHCCCCEEECCEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]