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The map label for this gene is exoB [H]

Identifier: 85858248

GI number: 85858248

Start: 407424

End: 408419

Strand: Direct

Name: exoB [H]

Synonym: SYN_01125

Alternate gene names: 85858248

Gene position: 407424-408419 (Clockwise)

Preceding gene: 85858247

Following gene: 85858249

Centisome position: 12.81

GC content: 61.14

Gene sequence:

>996_bases
ATGAGGATTCTGGTTACGGGCGGGGCCGGCTATATCGGCAGTCATGTGGTGAAGGCGCTGGGGGAGCAGGGGCATGACCT
GCTCATTTATGACAACCTGTCCACGGGGCACGACTGGGCTGTCCTTTACGGCAGGCTGGAGGTGGGGGAACTGGCAGATA
CCCGTCGTCTGGACGAAGTCCTGCAGGCGTTCCGGCCGGAGGCGGTTCTTCATTTCGCCGCGTCCATCCAGGTGGAAGAG
TCGGTCCGGGAGCCGCTTCGTTACTACCGCAACAACGTTGCTAATTCGCTGAATCTCCTGGACGCTATGGAGCGCCACGA
CGTCCGGAATCTCATCTATTCTTCCACGGCAGCCGTTTACGGCATTCCCGAGCGGATGCCCGTCGATGAATCTCTGCCTC
TGAATCCCATCAATCCCTACGGGGCCTCCAAGGTCATGATGGAAACGGTGCTCCGGGACATCGCCGATGCCAGGGAGAAC
TTCCGCTACATCGCCCTGCGCTACTTCAACGTGGCCGGCGCGGATGCCGGGAACCGGATCGGCCAGGCTTACGCGGACGC
CACCCATCTCATCACCCGGGCGCTCAAAACCGCCAACGGGCAATACCCCAAGCTGTCCGTCTTCGGGACGGATTACCCCA
CTCCCGACGGCACCTGCATCCGCGACTACATCCATGTGGACGACCTGGCCGACGCCCACATCCGGGCGCTGAATTATCTG
GTGGAGACGGGGAAGACGGAAATTATGAACTGCGGCTACGGCCACGGCTTTTCGGTTCGGGAGGTGGTGGACGTCGCGAA
AAAGGTGACGCGGATCGATTTTCCGGTCGAGGAAACGGAGCGCCGCGCTGGAGACCCGCCGGAACTTATCGCCGACAGTT
CGAAACTCCGCCGCCTCACCGGCTGGCTGCCCCGCCACGACGATCTGGAGTTCATCATTAGAACCGCCTGGGACTGGGAA
CTGAAGTACCGGTCCCTTCTGAAAGGAAAGGTGTGA

Upstream 100 bases:

>100_bases
GACAAAACGGGCTGGGCTTGCCGCAAAAATTCAGCCATTGAGAAGGCTGAACAGGAAAAAACCGAAACTCGGGTGAACCG
TTCGAAAGGAGATATCGAGG

Downstream 100 bases:

>100_bases
AACCCCTGACAATAAAACTCATACAAGAAAGGAATCCAAGTGAATCAATCCGATAAAACGTGGTCTGTCAGTCCTGGTGG
TGAATCATTTCCTTTGCCTT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRILVTGGAGYIGSHVVKALGEQGHDLLIYDNLSTGHDWAVLYGRLEVGELADTRRLDEVLQAFRPEAVLHFAASIQVEE
SVREPLRYYRNNVANSLNLLDAMERHDVRNLIYSSTAAVYGIPERMPVDESLPLNPINPYGASKVMMETVLRDIADAREN
FRYIALRYFNVAGADAGNRIGQAYADATHLITRALKTANGQYPKLSVFGTDYPTPDGTCIRDYIHVDDLADAHIRALNYL
VETGKTEIMNCGYGHGFSVREVVDVAKKVTRIDFPVEETERRAGDPPELIADSSKLRRLTGWLPRHDDLEFIIRTAWDWE
LKYRSLLKGKV

Sequences:

>Translated_331_residues
MRILVTGGAGYIGSHVVKALGEQGHDLLIYDNLSTGHDWAVLYGRLEVGELADTRRLDEVLQAFRPEAVLHFAASIQVEE
SVREPLRYYRNNVANSLNLLDAMERHDVRNLIYSSTAAVYGIPERMPVDESLPLNPINPYGASKVMMETVLRDIADAREN
FRYIALRYFNVAGADAGNRIGQAYADATHLITRALKTANGQYPKLSVFGTDYPTPDGTCIRDYIHVDDLADAHIRALNYL
VETGKTEIMNCGYGHGFSVREVVDVAKKVTRIDFPVEETERRAGDPPELIADSSKLRRLTGWLPRHDDLEFIIRTAWDWE
LKYRSLLKGKV
>Mature_331_residues
MRILVTGGAGYIGSHVVKALGEQGHDLLIYDNLSTGHDWAVLYGRLEVGELADTRRLDEVLQAFRPEAVLHFAASIQVEE
SVREPLRYYRNNVANSLNLLDAMERHDVRNLIYSSTAAVYGIPERMPVDESLPLNPINPYGASKVMMETVLRDIADAREN
FRYIALRYFNVAGADAGNRIGQAYADATHLITRALKTANGQYPKLSVFGTDYPTPDGTCIRDYIHVDDLADAHIRALNYL
VETGKTEIMNCGYGHGFSVREVVDVAKKVTRIDFPVEETERRAGDPPELIADSSKLRRLTGWLPRHDDLEFIIRTAWDWE
LKYRSLLKGKV

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=335, Percent_Identity=37.6119402985075, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI56118217, Length=335, Percent_Identity=37.6119402985075, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI189083684, Length=335, Percent_Identity=37.6119402985075, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI42516563, Length=310, Percent_Identity=26.1290322580645, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI7657641, Length=325, Percent_Identity=26.1538461538462, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=38.1381381381381, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1790049, Length=286, Percent_Identity=30.0699300699301, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI48994969, Length=370, Percent_Identity=25.1351351351351, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788353, Length=362, Percent_Identity=25.9668508287293, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=341, Percent_Identity=36.3636363636364, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71982038, Length=343, Percent_Identity=36.1516034985423, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17568069, Length=332, Percent_Identity=27.1084337349398, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17539532, Length=245, Percent_Identity=27.3469387755102, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=38.5756676557863, Blast_Score=213, Evalue=3e-56,
Organism=Drosophila melanogaster, GI19923002, Length=336, Percent_Identity=35.7142857142857, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI21356223, Length=311, Percent_Identity=26.6881028938907, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37264; Mature: 37264

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVTGGAGYIGSHVVKALGEQGHDLLIYDNLSTGHDWAVLYGRLEVGELADTRRLDEV
CEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHH
LQAFRPEAVLHFAASIQVEESVREPLRYYRNNVANSLNLLDAMERHDVRNLIYSSTAAVY
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
GIPERMPVDESLPLNPINPYGASKVMMETVLRDIADARENFRYIALRYFNVAGADAGNRI
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCHHH
GQAYADATHLITRALKTANGQYPKLSVFGTDYPTPDGTCIRDYIHVDDLADAHIRALNYL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VETGKTEIMNCGYGHGFSVREVVDVAKKVTRIDFPVEETERRAGDPPELIADSSKLRRLT
HHCCCHHEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHCCHHHHHHHH
GWLPRHDDLEFIIRTAWDWELKYRSLLKGKV
CCCCCCCCHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure
MRILVTGGAGYIGSHVVKALGEQGHDLLIYDNLSTGHDWAVLYGRLEVGELADTRRLDEV
CEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHH
LQAFRPEAVLHFAASIQVEESVREPLRYYRNNVANSLNLLDAMERHDVRNLIYSSTAAVY
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
GIPERMPVDESLPLNPINPYGASKVMMETVLRDIADARENFRYIALRYFNVAGADAGNRI
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCHHH
GQAYADATHLITRALKTANGQYPKLSVFGTDYPTPDGTCIRDYIHVDDLADAHIRALNYL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VETGKTEIMNCGYGHGFSVREVVDVAKKVTRIDFPVEETERRAGDPPELIADSSKLRRLT
HHCCCHHEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHCCHHHHHHHH
GWLPRHDDLEFIIRTAWDWELKYRSLLKGKV
CCCCCCCCHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]