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The map label for this gene is cysS [H]

Identifier: 85858183

GI number: 85858183

Start: 335988

End: 337640

Strand: Direct

Name: cysS [H]

Synonym: SYN_03026

Alternate gene names: 85858183

Gene position: 335988-337640 (Clockwise)

Preceding gene: 161347551

Following gene: 85858184

Centisome position: 10.57

GC content: 51.72

Gene sequence:

>1653_bases
TTGCCCTGTTTCCCTGAAACTTTTCCGTGTCCGGCATGTCTTTTTAAAAGAGGGGAGAAAACTCTTTCTGGTCATCAGAT
TGAAGGTCGCCGGACAGCAAGACCGCTGTCAGTCGGCAACTGCATGCGGAATGATCTCCTGTCGCGTTTTTTTTCGAGGA
GGGATCCTATGTCTTTAAAATTATACAACACCCTGAATAATAAGAAGGAAGTCTTTACTCCTATCCGAGAGGGCCGGGTC
GGGCTTTATGTATGCGGCATTACCGTATATGACGTATGCCATGTCGGGCATGCCCGGTCAGCCGTTGTGTTTGATGTTCT
CAAAAGGTACTTGGAATACAGGGGGTATGAAGTCACCTACATAAAGAATTTTACCGATGTCGACGATAAAATCATCGCCC
GTGCCAATGCGGAAGGGGTGAGCATTTCGGAGATCGCCAACCGTTATATTGCCTCGCATGATAAAGACATGGACCGTCTG
GGGGTTCTCCGGCCGACGGTTACTCCCCGGGCCACGGAGCATATCGGGGAAATGATCGAGCTCATCAGCAAGCTCCAGAA
ACGTGGTCTGGCCTATGCTGTAGACGGGAATGTCTATTATGCCGTGGAGCGGTTTCCGGGTTATGGAAAACTCTCCGGCC
GAAAACTTGAAGATATGATGGCCGGCGCCCGGATCGATGTCAATGAACATAAGAACAATCCCATGGATTTTGCCCTCTGG
AAGGCCAGTAAACCAAATGAACCGGCCTGGGACAGCCCCTGGGGGCCAGGGCGGCCGGGCTGGCACATTGAGTGTTCCGT
GATGAGCCAGAAATACCTCGGCGATACCTTTGACATCCATGGTGGCGGCGAGGATCTGGTTTTTCCTCACCATGAAAATG
AAATTGCCCAATCCGAGGGTGTAACAGGTAAGCCGCTGGCCAATATTTGGATTCACAACGGCTTTGTGAAAATCAACAGC
GAGAAGATGTCCAAATCGCTGGGCAACGTCTTTACCATCCAGGAAATGCTGACCCGTTATCATGCCGAGGTCATCCGTCT
GTTCATGCTGCAGAGTCACTATCGCAGCGCCGTGGATTTCTCCGAGGAATCGCTGTCGGAAGCGCGGCAGGGGATGGATC
GGTTCTATGGCACGCTAAAGGCCATCCAGGAAGTTCTGGCAGTGGCGGAGGAAGAGGCGTCTCCGATTTCTCCCGAAACC
CTGACGGGGAAAACAGCGGAACTGTATGCCCATGTTCAGGGATTGCCTGACCGTTTCGTCGAGGCCATGGATGATGATTT
GAATACAGCCCGGGCGATCGGTTACCTCTTTGATGCCGCCAGACAGATCAATGGATTTATTCGTGACGCGAAAATGGCCA
AATCGAAAGAGGGGTGGAAAGTCCTGGCGCTGGCCGGAAAGAGTATCAAGGATCTCGGATACGTATTGGGCCTTTTTCAG
GAAAATCCAGATGTCTATTTTTTGCAGGATCGTGAACGGGAAATCCGGAAACGGGGGCTTGAGCCTGCCGAGATTGAACT
GCTGATCGCCGATCGATGGGCGGCAAGAAACGACAAGGATTGGCATAAGGCTGACGAAATCCGTCAGCTTCTTACGGAAA
AAGGCATCGTCTTGAAAGATACTCCGACCGGTACGACCTGGAAGGTATCATGA

Upstream 100 bases:

>100_bases
GTTTCGGCCATTGATAATCTGGTTAAGGGCGCAGCCGGTCAGGCGATCCAGAATATGAACATTTTCTGCGGATTCCCGGA
GCACGAGGGGCTCGAGATGA

Downstream 100 bases:

>100_bases
AACCGAGAAAACGAGAGCAATATTGAGATAATCCGAAATATCTGGGACCGGGCCGAGCGCCTTCATTGCTTGACTTTTTG
AGCGTCGGCCTGTATGTTTG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MPCFPETFPCPACLFKRGEKTLSGHQIEGRRTARPLSVGNCMRNDLLSRFFSRRDPMSLKLYNTLNNKKEVFTPIREGRV
GLYVCGITVYDVCHVGHARSAVVFDVLKRYLEYRGYEVTYIKNFTDVDDKIIARANAEGVSISEIANRYIASHDKDMDRL
GVLRPTVTPRATEHIGEMIELISKLQKRGLAYAVDGNVYYAVERFPGYGKLSGRKLEDMMAGARIDVNEHKNNPMDFALW
KASKPNEPAWDSPWGPGRPGWHIECSVMSQKYLGDTFDIHGGGEDLVFPHHENEIAQSEGVTGKPLANIWIHNGFVKINS
EKMSKSLGNVFTIQEMLTRYHAEVIRLFMLQSHYRSAVDFSEESLSEARQGMDRFYGTLKAIQEVLAVAEEEASPISPET
LTGKTAELYAHVQGLPDRFVEAMDDDLNTARAIGYLFDAARQINGFIRDAKMAKSKEGWKVLALAGKSIKDLGYVLGLFQ
ENPDVYFLQDREREIRKRGLEPAEIELLIADRWAARNDKDWHKADEIRQLLTEKGIVLKDTPTGTTWKVS

Sequences:

>Translated_550_residues
MPCFPETFPCPACLFKRGEKTLSGHQIEGRRTARPLSVGNCMRNDLLSRFFSRRDPMSLKLYNTLNNKKEVFTPIREGRV
GLYVCGITVYDVCHVGHARSAVVFDVLKRYLEYRGYEVTYIKNFTDVDDKIIARANAEGVSISEIANRYIASHDKDMDRL
GVLRPTVTPRATEHIGEMIELISKLQKRGLAYAVDGNVYYAVERFPGYGKLSGRKLEDMMAGARIDVNEHKNNPMDFALW
KASKPNEPAWDSPWGPGRPGWHIECSVMSQKYLGDTFDIHGGGEDLVFPHHENEIAQSEGVTGKPLANIWIHNGFVKINS
EKMSKSLGNVFTIQEMLTRYHAEVIRLFMLQSHYRSAVDFSEESLSEARQGMDRFYGTLKAIQEVLAVAEEEASPISPET
LTGKTAELYAHVQGLPDRFVEAMDDDLNTARAIGYLFDAARQINGFIRDAKMAKSKEGWKVLALAGKSIKDLGYVLGLFQ
ENPDVYFLQDREREIRKRGLEPAEIELLIADRWAARNDKDWHKADEIRQLLTEKGIVLKDTPTGTTWKVS
>Mature_549_residues
PCFPETFPCPACLFKRGEKTLSGHQIEGRRTARPLSVGNCMRNDLLSRFFSRRDPMSLKLYNTLNNKKEVFTPIREGRVG
LYVCGITVYDVCHVGHARSAVVFDVLKRYLEYRGYEVTYIKNFTDVDDKIIARANAEGVSISEIANRYIASHDKDMDRLG
VLRPTVTPRATEHIGEMIELISKLQKRGLAYAVDGNVYYAVERFPGYGKLSGRKLEDMMAGARIDVNEHKNNPMDFALWK
ASKPNEPAWDSPWGPGRPGWHIECSVMSQKYLGDTFDIHGGGEDLVFPHHENEIAQSEGVTGKPLANIWIHNGFVKINSE
KMSKSLGNVFTIQEMLTRYHAEVIRLFMLQSHYRSAVDFSEESLSEARQGMDRFYGTLKAIQEVLAVAEEEASPISPETL
TGKTAELYAHVQGLPDRFVEAMDDDLNTARAIGYLFDAARQINGFIRDAKMAKSKEGWKVLALAGKSIKDLGYVLGLFQE
NPDVYFLQDREREIRKRGLEPAEIELLIADRWAARNDKDWHKADEIRQLLTEKGIVLKDTPTGTTWKVS

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=419, Percent_Identity=38.4248210023866, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI21269877, Length=357, Percent_Identity=31.6526610644258, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI303304987, Length=357, Percent_Identity=31.6526610644258, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI62240992, Length=245, Percent_Identity=39.5918367346939, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI10835051, Length=245, Percent_Identity=39.5918367346939, Blast_Score=184, Evalue=2e-46,
Organism=Escherichia coli, GI1786737, Length=491, Percent_Identity=47.8615071283096, Blast_Score=448, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17509795, Length=379, Percent_Identity=33.245382585752, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17509797, Length=379, Percent_Identity=33.245382585752, Blast_Score=174, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6324082, Length=314, Percent_Identity=37.2611464968153, Blast_Score=196, Evalue=8e-51,
Organism=Drosophila melanogaster, GI19922218, Length=494, Percent_Identity=35.6275303643725, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI19922364, Length=339, Percent_Identity=35.1032448377581, Blast_Score=184, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 62294; Mature: 62163

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCFPETFPCPACLFKRGEKTLSGHQIEGRRTARPLSVGNCMRNDLLSRFFSRRDPMSLK
CCCCCCCCCCHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
LYNTLNNKKEVFTPIREGRVGLYVCGITVYDVCHVGHARSAVVFDVLKRYLEYRGYEVTY
EEHHHCCCHHHHHHHHCCCEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEE
IKNFTDVDDKIIARANAEGVSISEIANRYIASHDKDMDRLGVLRPTVTPRATEHIGEMIE
ECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHHH
LISKLQKRGLAYAVDGNVYYAVERFPGYGKLSGRKLEDMMAGARIDVNEHKNNPMDFALW
HHHHHHHCCCEEEECCCEEEEEECCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCEEEEE
KASKPNEPAWDSPWGPGRPGWHIECSVMSQKYLGDTFDIHGGGEDLVFPHHENEIAQSEG
ECCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHCC
VTGKPLANIWIHNGFVKINSEKMSKSLGNVFTIQEMLTRYHAEVIRLFMLQSHYRSAVDF
CCCCCHHEEEEECCEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SEESLSEARQGMDRFYGTLKAIQEVLAVAEEEASPISPETLTGKTAELYAHVQGLPDRFV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHH
EAMDDDLNTARAIGYLFDAARQINGFIRDAKMAKSKEGWKVLALAGKSIKDLGYVLGLFQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHC
ENPDVYFLQDREREIRKRGLEPAEIELLIADRWAARNDKDWHKADEIRQLLTEKGIVLKD
CCCCEEEECCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEE
TPTGTTWKVS
CCCCCEEEEC
>Mature Secondary Structure 
PCFPETFPCPACLFKRGEKTLSGHQIEGRRTARPLSVGNCMRNDLLSRFFSRRDPMSLK
CCCCCCCCCHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
LYNTLNNKKEVFTPIREGRVGLYVCGITVYDVCHVGHARSAVVFDVLKRYLEYRGYEVTY
EEHHHCCCHHHHHHHHCCCEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEE
IKNFTDVDDKIIARANAEGVSISEIANRYIASHDKDMDRLGVLRPTVTPRATEHIGEMIE
ECCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHHH
LISKLQKRGLAYAVDGNVYYAVERFPGYGKLSGRKLEDMMAGARIDVNEHKNNPMDFALW
HHHHHHHCCCEEEECCCEEEEEECCCCCCCCCCCHHHHHHCCCEEEECCCCCCCCEEEEE
KASKPNEPAWDSPWGPGRPGWHIECSVMSQKYLGDTFDIHGGGEDLVFPHHENEIAQSEG
ECCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHCC
VTGKPLANIWIHNGFVKINSEKMSKSLGNVFTIQEMLTRYHAEVIRLFMLQSHYRSAVDF
CCCCCHHEEEEECCEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SEESLSEARQGMDRFYGTLKAIQEVLAVAEEEASPISPETLTGKTAELYAHVQGLPDRFV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCHHHH
EAMDDDLNTARAIGYLFDAARQINGFIRDAKMAKSKEGWKVLALAGKSIKDLGYVLGLFQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHC
ENPDVYFLQDREREIRKRGLEPAEIELLIADRWAARNDKDWHKADEIRQLLTEKGIVLKD
CCCCEEEECCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEE
TPTGTTWKVS
CCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA