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The map label for this gene is argC

Identifier: 161347551

GI number: 161347551

Start: 334967

End: 336004

Strand: Direct

Name: argC

Synonym: SYN_00234

Alternate gene names: 161347551

Gene position: 334967-336004 (Clockwise)

Preceding gene: 85858181

Following gene: 85858183

Centisome position: 10.54

GC content: 52.41

Gene sequence:

>1038_bases
ATGATAAAAGTTGGAATCTACGGGGCCAGTGGTTATACGGGGCAGGAATGCCTCAGGTTGCTTCTTCGCCATTCCGGCGT
AGAGGTGGTCGCGATCACCTCGAGGCGATATGCCGGTCTTCCCATCGCCGACGTCTATCCTGTGTTTGCGGGGTTAACGT
CATTGGCATTTATGAATGCCGCTCCCCATGAAGTTGCCCGGGAGGCCGATGTGATTTTTCTGGCGTTGCCCCACAGCGAA
TCCATGAAGGTGGCCCCAATATTCTGGGAAAGCGGGAAGAAAGTAATCGATCTCAGCGCGGATTTCCGGTTACGGGATGT
CGATGTTTATGAATCCTGGTACGGAAGGCATGTCTCCTCCCAGCTTGTTCCGCAAACCGTTTACGGTATTCCTGAGCTCT
ACCGGGAGGAAGTGGCGAAAACCCGGTTTGTGGCGAATCCCGGATGTTATCCAACCAGCATTATTCTGGGAAGCGCACCT
GCTCTCAAAAACGGACTGATTGACACGACCTCGGTGATTGTGGATTCCAAATCCGGCACCAGCGGCGCTGGTCGTGAACC
CGCAGTGGGGTCTCTTTTCTGTGAAGTCAATGAAGGATTCAAAGCCTATAAAGTTTGCAACCACCGTCATACTCCTGAGA
TTGAACAGGAATTGAGTCGTCTTGCCGGCCAGGAAATAAGAGTTTCCTTCACACCCCACCTGCTTCCGCTCGATCGGGGG
ATTCTAAGCACCATTTACGCGACATTGACCCGGGATATCACAGGCAAAGAAGTGACGGAACTATACCGGAATTATTATGA
GGGAGAAAGATTTGTCCGGATTTGCCAGCCGGGAAGTTTCCCGAATGTGGCCTTTGTTCGAGGGTCCAATTACTGTGATA
TCGGCGTAGCGGTGGATGCGCGCACTCAACGGTTGATTGTTGTTTCGGCCATTGATAATCTGGTTAAGGGCGCAGCCGGT
CAGGCGATCCAGAATATGAACATTTTCTGCGGATTCCCGGAGCACGAGGGGCTCGAGATGATTGCCCTGTTTCCCTGA

Upstream 100 bases:

>100_bases
GCGGCAATGATGCCGGTGTTTTTGGCCGAAAACCGGCAAACGGCTATGGATGAACCGTTTCGGCATCAGGATGAGTAACC
AGAATCAAAGTGAGGGTTAT

Downstream 100 bases:

>100_bases
AACTTTTCCGTGTCCGGCATGTCTTTTTAAAAGAGGGGAGAAAACTCTTTCTGGTCATCAGATTGAAGGTCGCCGGACAG
CAAGACCGCTGTCAGTCGGC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MIKVGIYGASGYTGQECLRLLLRHSGVEVVAITSRRYAGLPIADVYPVFAGLTSLAFMNAAPHEVAREADVIFLALPHSE
SMKVAPIFWESGKKVIDLSADFRLRDVDVYESWYGRHVSSQLVPQTVYGIPELYREEVAKTRFVANPGCYPTSIILGSAP
ALKNGLIDTTSVIVDSKSGTSGAGREPAVGSLFCEVNEGFKAYKVCNHRHTPEIEQELSRLAGQEIRVSFTPHLLPLDRG
ILSTIYATLTRDITGKEVTELYRNYYEGERFVRICQPGSFPNVAFVRGSNYCDIGVAVDARTQRLIVVSAIDNLVKGAAG
QAIQNMNIFCGFPEHEGLEMIALFP

Sequences:

>Translated_345_residues
MIKVGIYGASGYTGQECLRLLLRHSGVEVVAITSRRYAGLPIADVYPVFAGLTSLAFMNAAPHEVAREADVIFLALPHSE
SMKVAPIFWESGKKVIDLSADFRLRDVDVYESWYGRHVSSQLVPQTVYGIPELYREEVAKTRFVANPGCYPTSIILGSAP
ALKNGLIDTTSVIVDSKSGTSGAGREPAVGSLFCEVNEGFKAYKVCNHRHTPEIEQELSRLAGQEIRVSFTPHLLPLDRG
ILSTIYATLTRDITGKEVTELYRNYYEGERFVRICQPGSFPNVAFVRGSNYCDIGVAVDARTQRLIVVSAIDNLVKGAAG
QAIQNMNIFCGFPEHEGLEMIALFP
>Mature_345_residues
MIKVGIYGASGYTGQECLRLLLRHSGVEVVAITSRRYAGLPIADVYPVFAGLTSLAFMNAAPHEVAREADVIFLALPHSE
SMKVAPIFWESGKKVIDLSADFRLRDVDVYESWYGRHVSSQLVPQTVYGIPELYREEVAKTRFVANPGCYPTSIILGSAP
ALKNGLIDTTSVIVDSKSGTSGAGREPAVGSLFCEVNEGFKAYKVCNHRHTPEIEQELSRLAGQEIRVSFTPHLLPLDRG
ILSTIYATLTRDITGKEVTELYRNYYEGERFVRICQPGSFPNVAFVRGSNYCDIGVAVDARTQRLIVVSAIDNLVKGAAG
QAIQNMNIFCGFPEHEGLEMIALFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=344, Percent_Identity=37.2093023255814, Blast_Score=196, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6320913, Length=347, Percent_Identity=32.5648414985591, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 37884; Mature: 37884

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVGIYGASGYTGQECLRLLLRHSGVEVVAITSRRYAGLPIADVYPVFAGLTSLAFMNA
CEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
APHEVAREADVIFLALPHSESMKVAPIFWESGKKVIDLSADFRLRDVDVYESWYGRHVSS
CHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCEEEEECCCCEEEEEHHHHHHHCCCHHH
QLVPQTVYGIPELYREEVAKTRFVANPGCYPTSIILGSAPALKNGLIDTTSVIVDSKSGT
HHCHHHHHCCHHHHHHHHHHHHEECCCCCCCCEEEECCCCHHHCCCCCCEEEEEECCCCC
SGAGREPAVGSLFCEVNEGFKAYKVCNHRHTPEIEQELSRLAGQEIRVSFTPHLLPLDRG
CCCCCCCCCEEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCEEEHHHH
ILSTIYATLTRDITGKEVTELYRNYYEGERFVRICQPGSFPNVAFVRGSNYCDIGVAVDA
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCEEEEEEEEEC
RTQRLIVVSAIDNLVKGAAGQAIQNMNIFCGFPEHEGLEMIALFP
CCCEEEEEHHHHHHHHCCCCHHHHCCEEEEECCCCCCCEEEEECC
>Mature Secondary Structure
MIKVGIYGASGYTGQECLRLLLRHSGVEVVAITSRRYAGLPIADVYPVFAGLTSLAFMNA
CEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
APHEVAREADVIFLALPHSESMKVAPIFWESGKKVIDLSADFRLRDVDVYESWYGRHVSS
CHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCEEEEECCCCEEEEEHHHHHHHCCCHHH
QLVPQTVYGIPELYREEVAKTRFVANPGCYPTSIILGSAPALKNGLIDTTSVIVDSKSGT
HHCHHHHHCCHHHHHHHHHHHHEECCCCCCCCEEEECCCCHHHCCCCCCEEEEEECCCCC
SGAGREPAVGSLFCEVNEGFKAYKVCNHRHTPEIEQELSRLAGQEIRVSFTPHLLPLDRG
CCCCCCCCCEEEEEEECCCCHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCEEEHHHH
ILSTIYATLTRDITGKEVTELYRNYYEGERFVRICQPGSFPNVAFVRGSNYCDIGVAVDA
HHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCEEEEEEEEEC
RTQRLIVVSAIDNLVKGAAGQAIQNMNIFCGFPEHEGLEMIALFP
CCCEEEEEHHHHHHHHCCCCHHHHCCEEEEECCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA