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The map label for this gene is cysQ [H]

Identifier: 85375532

GI number: 85375532

Start: 2725185

End: 2725985

Strand: Direct

Name: cysQ [H]

Synonym: ELI_13525

Alternate gene names: 85375532

Gene position: 2725185-2725985 (Clockwise)

Preceding gene: 85375530

Following gene: 85375534

Centisome position: 89.28

GC content: 66.17

Gene sequence:

>801_bases
ATGATCGATCACGCGCGCCTACAGGCGATCGTCCGCGAAGCGGGCGCAATCGCCCAATCGCATTGGCCCGGCGCGGGCCA
TGATCTCGACGCGTGGGAGAAGCAGCCCGGCGATCCGGTGTGCGAGGCCGACCTTGCGGTGGACTCATTCCTGAAACGCG
AACTCGGCGCTCTCCTGCCGGCGGCGGGCTGGCTGTCGGAAGAGACGGCCGATGCGCCCGGAAGGCTCGACAACCGGCTG
ATCTGGCTGGTCGATCCGATCGACGGTACGCGCGATTTTATCCGCGGGCGCAAGGGCTGGGCGGTCTCGGTCGCACTCAT
CAGCGAAGGACGGCCGCTGATCGGGATGCTGAACGCTCCTGCTCGCGAGGAGGAATGGATAGCCGTTGCCGGACAGGGCG
CGCAACGCAACGGCCGGCGCCTGCGCGCCTCGCAGCGGAGCACATTCGTCGGCGCGCGGATCCCTGCCGATTCGCTGATG
AAGGAAGACCGCATTTTCGAAATGGTCGACAAACCCAACGGCATCGCCCTGCGCGTGGCGATGATTGCCGCCGACGAGGC
CGACCTGGTGGCGACCCTGCGCTGGGGCTACGAATGGGATATAGGTGCCGCGACGCTGATCGCGCGGGAAGCGGGCGCGG
CAATCAGCGATGCATGGGGCAACCCGCTCGGCTACAACAAACGCGATCCGAGAGCCTTCGGCCTGTTGGTCAGCGCGCCC
GGCATTCACGCCGAGGCTGTGACGCACCTGAAGCGGCGCGCCGAGCATTATACGAGGAAATTCGCCGACAAGCTGAAATA
G

Upstream 100 bases:

>100_bases
ATCCTGTTGACGTGAATCGGTATCGATTTGCGACGCGCCTAAGCATGGATCGTCGCGCTTGAAAAGGTGCCATTCGGGTA
GCATGGCTTGACGACGAACC

Downstream 100 bases:

>100_bases
CGAAAGGGCCGGCATTGCTGCCGACCCTTCCCGTTCTGCCGCGGGGGCAGAGCTATGCGATGTCGCTTGGCCCTTCGATT
ACTGGGCGCGGGCGCGAGCC

Product: inositol monophosphatase family protein

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MIDHARLQAIVREAGAIAQSHWPGAGHDLDAWEKQPGDPVCEADLAVDSFLKRELGALLPAAGWLSEETADAPGRLDNRL
IWLVDPIDGTRDFIRGRKGWAVSVALISEGRPLIGMLNAPAREEEWIAVAGQGAQRNGRRLRASQRSTFVGARIPADSLM
KEDRIFEMVDKPNGIALRVAMIAADEADLVATLRWGYEWDIGAATLIAREAGAAISDAWGNPLGYNKRDPRAFGLLVSAP
GIHAEAVTHLKRRAEHYTRKFADKLK

Sequences:

>Translated_266_residues
MIDHARLQAIVREAGAIAQSHWPGAGHDLDAWEKQPGDPVCEADLAVDSFLKRELGALLPAAGWLSEETADAPGRLDNRL
IWLVDPIDGTRDFIRGRKGWAVSVALISEGRPLIGMLNAPAREEEWIAVAGQGAQRNGRRLRASQRSTFVGARIPADSLM
KEDRIFEMVDKPNGIALRVAMIAADEADLVATLRWGYEWDIGAATLIAREAGAAISDAWGNPLGYNKRDPRAFGLLVSAP
GIHAEAVTHLKRRAEHYTRKFADKLK
>Mature_266_residues
MIDHARLQAIVREAGAIAQSHWPGAGHDLDAWEKQPGDPVCEADLAVDSFLKRELGALLPAAGWLSEETADAPGRLDNRL
IWLVDPIDGTRDFIRGRKGWAVSVALISEGRPLIGMLNAPAREEEWIAVAGQGAQRNGRRLRASQRSTFVGARIPADSLM
KEDRIFEMVDKPNGIALRVAMIAADEADLVATLRWGYEWDIGAATLIAREAGAAISDAWGNPLGYNKRDPRAFGLLVSAP
GIHAEAVTHLKRRAEHYTRKFADKLK

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=205, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1788882, Length=226, Percent_Identity=29.646017699115, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790659, Length=240, Percent_Identity=30.8333333333333, Blast_Score=79, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320493, Length=148, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21357957, Length=211, Percent_Identity=26.0663507109005, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24664918, Length=261, Percent_Identity=24.1379310344828, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357329, Length=202, Percent_Identity=28.7128712871287, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357303, Length=238, Percent_Identity=25.6302521008403, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29093; Mature: 29093

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDHARLQAIVREAGAIAQSHWPGAGHDLDAWEKQPGDPVCEADLAVDSFLKRELGALLP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
AAGWLSEETADAPGRLDNRLIWLVDPIDGTRDFIRGRKGWAVSVALISEGRPLIGMLNAP
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCEEEEEEECCCCCEEEECCCC
AREEEWIAVAGQGAQRNGRRLRASQRSTFVGARIPADSLMKEDRIFEMVDKPNGIALRVA
CCCCCEEEEECCCCCCCCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEE
MIAADEADLVATLRWGYEWDIGAATLIAREAGAAISDAWGNPLGYNKRDPRAFGLLVSAP
EEECCCCCEEEEEECCEEECCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCHHEEEEEECC
GIHAEAVTHLKRRAEHYTRKFADKLK
CCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDHARLQAIVREAGAIAQSHWPGAGHDLDAWEKQPGDPVCEADLAVDSFLKRELGALLP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
AAGWLSEETADAPGRLDNRLIWLVDPIDGTRDFIRGRKGWAVSVALISEGRPLIGMLNAP
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCEEEEEEECCCCCEEEECCCC
AREEEWIAVAGQGAQRNGRRLRASQRSTFVGARIPADSLMKEDRIFEMVDKPNGIALRVA
CCCCCEEEEECCCCCCCCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEE
MIAADEADLVATLRWGYEWDIGAATLIAREAGAAISDAWGNPLGYNKRDPRAFGLLVSAP
EEECCCCCEEEEEECCEEECCCHHHHHHHHHCCHHHHCCCCCCCCCCCCCHHEEEEEECC
GIHAEAVTHLKRRAEHYTRKFADKLK
CCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]