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The map label for this gene is des [H]

Identifier: 85374745

GI number: 85374745

Start: 1953306

End: 1954340

Strand: Direct

Name: des [H]

Synonym: ELI_09590

Alternate gene names: 85374745

Gene position: 1953306-1954340 (Clockwise)

Preceding gene: 85374744

Following gene: 85374749

Centisome position: 63.99

GC content: 63.96

Gene sequence:

>1035_bases
ATGACTGCCAGCGAGGCTTCGCCTGACACCATAGACGCGCGCCAGCTCGCGCAGGACCTCAAGCCCTTCCACCGCCCACG
CGTGTGGCGCAGCAGTATCGAGCTCGCGATTACGCTGGTGCCTTTCGTTGCGCTCTACGCGGCCATGTTGCTGGCGCTCG
ATGCCGGATACTGGCTGGCACTTGTCGGAACGCCGCTGGCAGGCCTGCTGCTGCTGCGCCTTTTCATCATCCAGCACGAC
TGCGGCCACGGTTCCTTCTTCAAGCGGCGCGCGACGAACGACTGGGTCGGACGCGCACTCGGCGTGCTCACGCTCACACC
CTACGATTGCTGGCGGCGCAGCCATGCGCTGCATCATGCGGCGACCGGCAACCTCGACGCGCGCGGCTTCGGCGATGTCG
ATACCCTTACGGTGCGCGAATTTTGCGAAAGTTCGCGCTGGCAGCGCGCCTTCTATCGCGCCTACCGCCATCCCCTGGTG
CTGATGGGGCTCGGCCCGGCCTATCTGTTCCTGCTGCGCCATCGCCTGCCGATCGGGCTGATGACCGCCGGCAGTATCTA
CTGGGTCAGTGCCATGGTCACCAATCTCGTGATCGCCGCGATCCTGTTCGGCCTGATCTGGACTTTCGGTTTCGCGACCG
TCGCGCTGGTCTTCTTCCCGGTCCTACTGACGGCAGCGAGCATGGGCGTATGGTTGTTCTACATCCAGCACCAGTTCGAA
GACGCGGTGTGGGACAAGCGGGAGGACTGGTCCTTCCACCACGCGGCCCTCGCCGGCAGTACCTATCTCGACCTGCCAAG
CGTGCTGCGCTGGTTTACCGGCAATATCGGCATCCACCATGTGCATCATTTGGCGAGCCGCATTCCATTCTACCGCCTGC
CCGAAGTGCTGCGCGAATTCCCTGCACTGACCGAGGTCAATCGCTACACCACGCGCCAGGCGTTCAAGCCGCTGCTGCTG
GCGCTTTGGTGCGAGGACGAGCGACGACTGGTGACGTTCAGCGAGGCGAAAAGACGGGTCGCTGCCCGGGGTTAG

Upstream 100 bases:

>100_bases
ATGGCGTGACCCGCTTAAGGCGGCATACACGACCGGAGGCGCATAGCCGCCTTCTCAACCCCAGCTACCGCGAGATTTTG
TGAACGCACCTTCCTTTGAC

Downstream 100 bases:

>100_bases
GCCGTGAACGGACCGGTCACTGTCGTCAGTCGCCCGACGGATCGACGAAATTGCCCGCCCCGATATTGGCGTTCACCACG
CCGCCGTCGATCGCCAGCGT

Product: putative fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTASEASPDTIDARQLAQDLKPFHRPRVWRSSIELAITLVPFVALYAAMLLALDAGYWLALVGTPLAGLLLLRLFIIQHD
CGHGSFFKRRATNDWVGRALGVLTLTPYDCWRRSHALHHAATGNLDARGFGDVDTLTVREFCESSRWQRAFYRAYRHPLV
LMGLGPAYLFLLRHRLPIGLMTAGSIYWVSAMVTNLVIAAILFGLIWTFGFATVALVFFPVLLTAASMGVWLFYIQHQFE
DAVWDKREDWSFHHAALAGSTYLDLPSVLRWFTGNIGIHHVHHLASRIPFYRLPEVLREFPALTEVNRYTTRQAFKPLLL
ALWCEDERRLVTFSEAKRRVAARG

Sequences:

>Translated_344_residues
MTASEASPDTIDARQLAQDLKPFHRPRVWRSSIELAITLVPFVALYAAMLLALDAGYWLALVGTPLAGLLLLRLFIIQHD
CGHGSFFKRRATNDWVGRALGVLTLTPYDCWRRSHALHHAATGNLDARGFGDVDTLTVREFCESSRWQRAFYRAYRHPLV
LMGLGPAYLFLLRHRLPIGLMTAGSIYWVSAMVTNLVIAAILFGLIWTFGFATVALVFFPVLLTAASMGVWLFYIQHQFE
DAVWDKREDWSFHHAALAGSTYLDLPSVLRWFTGNIGIHHVHHLASRIPFYRLPEVLREFPALTEVNRYTTRQAFKPLLL
ALWCEDERRLVTFSEAKRRVAARG
>Mature_343_residues
TASEASPDTIDARQLAQDLKPFHRPRVWRSSIELAITLVPFVALYAAMLLALDAGYWLALVGTPLAGLLLLRLFIIQHDC
GHGSFFKRRATNDWVGRALGVLTLTPYDCWRRSHALHHAATGNLDARGFGDVDTLTVREFCESSRWQRAFYRAYRHPLVL
MGLGPAYLFLLRHRLPIGLMTAGSIYWVSAMVTNLVIAAILFGLIWTFGFATVALVFFPVLLTAASMGVWLFYIQHQFED
AVWDKREDWSFHHAALAGSTYLDLPSVLRWFTGNIGIHHVHHLASRIPFYRLPEVLREFPALTEVNRYTTRQAFKPLLLA
LWCEDERRLVTFSEAKRRVAARG

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71999459, Length=322, Percent_Identity=24.8447204968944, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 39149; Mature: 39018

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASEASPDTIDARQLAQDLKPFHRPRVWRSSIELAITLVPFVALYAAMLLALDAGYWLA
CCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LVGTPLAGLLLLRLFIIQHDCGHGSFFKRRATNDWVGRALGVLTLTPYDCWRRSHALHHA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHEECCHHHHHHHHHHHHH
ATGNLDARGFGDVDTLTVREFCESSRWQRAFYRAYRHPLVLMGLGPAYLFLLRHRLPIGL
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCEEE
MTAGSIYWVSAMVTNLVIAAILFGLIWTFGFATVALVFFPVLLTAASMGVWLFYIQHQFE
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAVWDKREDWSFHHAALAGSTYLDLPSVLRWFTGNIGIHHVHHLASRIPFYRLPEVLREF
HHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHC
PALTEVNRYTTRQAFKPLLLALWCEDERRLVTFSEAKRRVAARG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCC
>Mature Secondary Structure 
TASEASPDTIDARQLAQDLKPFHRPRVWRSSIELAITLVPFVALYAAMLLALDAGYWLA
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LVGTPLAGLLLLRLFIIQHDCGHGSFFKRRATNDWVGRALGVLTLTPYDCWRRSHALHHA
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHEECCHHHHHHHHHHHHH
ATGNLDARGFGDVDTLTVREFCESSRWQRAFYRAYRHPLVLMGLGPAYLFLLRHRLPIGL
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCEEE
MTAGSIYWVSAMVTNLVIAAILFGLIWTFGFATVALVFFPVLLTAASMGVWLFYIQHQFE
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAVWDKREDWSFHHAALAGSTYLDLPSVLRWFTGNIGIHHVHHLASRIPFYRLPEVLREF
HHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHC
PALTEVNRYTTRQAFKPLLLALWCEDERRLVTFSEAKRRVAARG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]