Click here to switch to the map view.

The map label for this gene is gcp

Identifier: 85374659

GI number: 85374659

Start: 1862985

End: 1864019

Strand: Direct

Name: gcp

Synonym: ELI_09160

Alternate gene names: 85374659

Gene position: 1862985-1864019 (Clockwise)

Preceding gene: 85374655

Following gene: 85374660

Centisome position: 61.03

GC content: 65.99

Gene sequence:

>1035_bases
ATGAGGATAGTCCTCGGCATAGAATCGAGCTGCGACGAAACTGCGGCCGCGCTGGTCGCCACCGATCGCACCATACTGGC
GCAGCATATCGCTTCGCAGGACGAGGCGCATGCACCCTATGGCGGCGTGGTACCCGAGATCGCCGCGCGCGCTCATGCCG
AGCGACTCGCGCCGATGATCGAAGCGGTGATGCAAGAAGCGGGCGTCGACTACGCCGACCTCGACGCGATTGCCGCGACG
GCCGGCCCGGGCCTGATCGGGGGCGTGATGGTCGGTCTGGTCAGCGCCAAGGCCATCGCCATGGCGGCGGGCAAGCCACT
GATCGCGATCAACCATCTGGAAGGCCATGCGCTCAGCTCGCGGCTGGCCGATTCCGAATTGGAATTTCCCTATGCCCTGC
TGCTCGTTTCGGGCGGGCATTGCCAGATCCTGCTGGTCGAAGGCGTGGGTCAATATCGCCGCCTCGCCACCACCATCGAC
GATGCACTCGGCGAAGCCTTCGACAAGACCGCCAAGATCCTTGGCCTTGGCTATCCCGGCGGGCCGGCGGTCGAAAAGCT
GGCGCGCGACGGCGACGCGCAGGCTGTGCCTCTCCCCCGCCCGATGCTGGGCAGCGCAGAGCCGCATTTCAGCTTTGCAG
GCCTCAAGAGCGCGGTGTTGCGAGCCAAGGAAAGCGGCGATCATGAGGACGCAGACATCGCAGCGAGCTTTCAGCAGGCA
GCGGTCGATTGCATTCTGGATCGCTTGCAAGTGGCGTTGGGCGGGGATGACTGGCCCCCTGCGCTCGTCGTTGCGGGTGG
TGTTGCAGCCAACCAGACGATCCGCGCAGCGCTGGAAGGATTTGCAGCAGATCGCTCGATGCGCTTCGTCGCGCCGCCCT
TGGCGCTGTGCACAGACAATGCGGCCATGATTGGCTGGGCCGGGTGCGAGCGGCTAGACTTGGAACAGGACGATCCGCTC
GATTTCCGCGCGCGGCCGCGCTGGCCGCTCGATCCGGAAGCGGAGCCGGTACGCGGGGCGGGAGTGAAGGCGTGA

Upstream 100 bases:

>100_bases
CCATGGCGAGCGGAGAAGTGCGGGTTCCGAGGCGGAGGATGGGCGTCTCACTCATGCGGTTCGCTTGCCCTAGCGAGAGC
TTCGTCTAAGGGGAAGCCGC

Downstream 100 bases:

>100_bases
CGGCAGAAATCGCAGTCCTCGGCGGCGGCGCATGGGGCACCGCGCTTGCGCAGATGCTCGCCAGCGACGGGCAAGATGTC
TTGCTGTGGGCTCGAGAAAG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MRIVLGIESSCDETAAALVATDRTILAQHIASQDEAHAPYGGVVPEIAARAHAERLAPMIEAVMQEAGVDYADLDAIAAT
AGPGLIGGVMVGLVSAKAIAMAAGKPLIAINHLEGHALSSRLADSELEFPYALLLVSGGHCQILLVEGVGQYRRLATTID
DALGEAFDKTAKILGLGYPGGPAVEKLARDGDAQAVPLPRPMLGSAEPHFSFAGLKSAVLRAKESGDHEDADIAASFQQA
AVDCILDRLQVALGGDDWPPALVVAGGVAANQTIRAALEGFAADRSMRFVAPPLALCTDNAAMIGWAGCERLDLEQDDPL
DFRARPRWPLDPEAEPVRGAGVKA

Sequences:

>Translated_344_residues
MRIVLGIESSCDETAAALVATDRTILAQHIASQDEAHAPYGGVVPEIAARAHAERLAPMIEAVMQEAGVDYADLDAIAAT
AGPGLIGGVMVGLVSAKAIAMAAGKPLIAINHLEGHALSSRLADSELEFPYALLLVSGGHCQILLVEGVGQYRRLATTID
DALGEAFDKTAKILGLGYPGGPAVEKLARDGDAQAVPLPRPMLGSAEPHFSFAGLKSAVLRAKESGDHEDADIAASFQQA
AVDCILDRLQVALGGDDWPPALVVAGGVAANQTIRAALEGFAADRSMRFVAPPLALCTDNAAMIGWAGCERLDLEQDDPL
DFRARPRWPLDPEAEPVRGAGVKA
>Mature_344_residues
MRIVLGIESSCDETAAALVATDRTILAQHIASQDEAHAPYGGVVPEIAARAHAERLAPMIEAVMQEAGVDYADLDAIAAT
AGPGLIGGVMVGLVSAKAIAMAAGKPLIAINHLEGHALSSRLADSELEFPYALLLVSGGHCQILLVEGVGQYRRLATTID
DALGEAFDKTAKILGLGYPGGPAVEKLARDGDAQAVPLPRPMLGSAEPHFSFAGLKSAVLRAKESGDHEDADIAASFQQA
AVDCILDRLQVALGGDDWPPALVVAGGVAANQTIRAALEGFAADRSMRFVAPPLALCTDNAAMIGWAGCERLDLEQDDPL
DFRARPRWPLDPEAEPVRGAGVKA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=362, Percent_Identity=36.4640883977901, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI8923380, Length=333, Percent_Identity=29.1291291291291, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1789445, Length=331, Percent_Identity=46.5256797583082, Blast_Score=283, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17557464, Length=323, Percent_Identity=34.6749226006192, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71995670, Length=322, Percent_Identity=29.1925465838509, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320099, Length=367, Percent_Identity=31.8801089918256, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=25, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI20129063, Length=353, Percent_Identity=34.8441926345609, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21357207, Length=348, Percent_Identity=27.0114942528736, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_ERYLH (Q2N8R7)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458721.1
- ProteinModelPortal:   Q2N8R7
- SMR:   Q2N8R7
- STRING:   Q2N8R7
- MEROPS:   M22.001
- GeneID:   3869609
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_09160
- NMPDR:   fig|314225.3.peg.1210
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   Q2N8R7
- ProtClustDB:   PRK09604
- BioCyc:   ELIT314225:ELI_09160-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 35785; Mature: 35785

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVLGIESSCDETAAALVATDRTILAQHIASQDEAHAPYGGVVPEIAARAHAERLAPMI
CEEEEECCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EAVMQEAGVDYADLDAIAATAGPGLIGGVMVGLVSAKAIAMAAGKPLIAINHLEGHALSS
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHH
RLADSELEFPYALLLVSGGHCQILLVEGVGQYRRLATTIDDALGEAFDKTAKILGLGYPG
HHCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
GPAVEKLARDGDAQAVPLPRPMLGSAEPHFSFAGLKSAVLRAKESGDHEDADIAASFQQA
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AVDCILDRLQVALGGDDWPPALVVAGGVAANQTIRAALEGFAADRSMRFVAPPLALCTDN
HHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCHHHCCCC
AAMIGWAGCERLDLEQDDPLDFRARPRWPLDPEAEPVRGAGVKA
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRIVLGIESSCDETAAALVATDRTILAQHIASQDEAHAPYGGVVPEIAARAHAERLAPMI
CEEEEECCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EAVMQEAGVDYADLDAIAATAGPGLIGGVMVGLVSAKAIAMAAGKPLIAINHLEGHALSS
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHH
RLADSELEFPYALLLVSGGHCQILLVEGVGQYRRLATTIDDALGEAFDKTAKILGLGYPG
HHCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
GPAVEKLARDGDAQAVPLPRPMLGSAEPHFSFAGLKSAVLRAKESGDHEDADIAASFQQA
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AVDCILDRLQVALGGDDWPPALVVAGGVAANQTIRAALEGFAADRSMRFVAPPLALCTDN
HHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCHHHCCCC
AAMIGWAGCERLDLEQDDPLDFRARPRWPLDPEAEPVRGAGVKA
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA