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The map label for this gene is cpg2 [H]

Identifier: 85374610

GI number: 85374610

Start: 1816397

End: 1817590

Strand: Direct

Name: cpg2 [H]

Synonym: ELI_08915

Alternate gene names: 85374610

Gene position: 1816397-1817590 (Clockwise)

Preceding gene: 85374607

Following gene: 85374611

Centisome position: 59.51

GC content: 64.49

Gene sequence:

>1194_bases
ATGAAACCATCCTATCTCGAATCCATAGATCAGGCGGCGATGTGCGAACAGGCTTTGGCCTGGAGCGCCGTCAATTCGGG
TACCGGCAATCTCGACGGTCTGAAGACTGTCGCTGGGATGCTCGCCGATGCCTTCGCTGCCCTCCCGGGCGAGGTCGAAC
TGCGCGACCCCGCACCGGTCACGGCGATCAGCGCGGACGGGCAGGAATTCGACAAGCAGCATGGCCAGCATCTCGTCGTG
CGCGTACGCCCCGATGCGGAGCGGCGGGTGGTGCTGACGGGGCATATGGACACGGTGTTTCCAATCGATCACCCGTTCCA
GGAAAATAGTTGGCTCGACGACGATGTCGTCAACGGCCCCGGTACCGCCGACATGAAAGGCGGGATCGCGGTCATGCTGC
ATGCACTGCTGGCGCTCGAGCAATCGGAACACGGGCGAAGCCTCGGCTACGACGTGATGATCAACTCGGACGAGGAAACC
GGTTCGCTGTCTTCCGCCAAGCTGATCGAGGAACTTGCGAACGGCAAATATGCCGCCCTCACTTACGAACCCTCGGCGAC
GCCCGAAGGCACCCTCGCCCATGCGCGCGGCGGGACAGGCAATTACTCACTGATCGTCAAGGGCCGCTCCGCTCATGCGG
GTCGCAATCCGCAGGACGGGCGCAACGCGCTGGTCGCGGCGGCAGCGCTGGCGGTCGGCCTGAAGGACCTGCAAACCGAG
GATTGCCCGGTCAATCCGGCCAAGATCGAAGGCGGCGCGGCCAACAATGTCGTGCCCGACAATGCCGTGCTGCGCTTCAA
CATCCGCCCCAAGGAACCGAGCGCGGGTGAGCGGTTCGAGGCGGGATTGCAGGGGCTGATGGCCGCTATCCGGCAGGCAC
ATGAAGTCAGCGTCGACCTGCATGGCGGCGTCACGCGCCCGCCCAAACCGGTCGACCGCAAGGCGCAGCGCCTGTTCGAT
CTCGTCCGCGATTGCGGGGCAGAGCTTGGCCAGCATATCGACTGGCAATCGACCGGAGGCGTGTGCGACGGCAACAACAT
CGCCGCCTGCGGGGTGCCCGTCGTCGATACGATGGGCGTGCGCGGCGGCAAGATCCATTCGCCCGACGAATTCATGATCG
TGCCGAGCCTCAGCGAACGCGCGGCACTCAGCGCCCTTGTTTTGCACCGGCTGGCATCGGGAGATGAGCTTTGA

Upstream 100 bases:

>100_bases
GGCGCTATCTGTCTGGGGAGGACGCAAGCGCCTATGGCTTAGGGGACGAGCAATTGCAACGGGTTGGAAGGGGTGAAAAC
CCCCGCTAGAGCGGTTGCCG

Downstream 100 bases:

>100_bases
GTTTCCGCCTGCGCGCCGCGCGCACCGAAGATATCGAACCGCTCTACGAAATGGCCAAGCTGACCGGCGGCGGCTTCACC
AATCTGCCCGCCGATCGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKPSYLESIDQAAMCEQALAWSAVNSGTGNLDGLKTVAGMLADAFAALPGEVELRDPAPVTAISADGQEFDKQHGQHLVV
RVRPDAERRVVLTGHMDTVFPIDHPFQENSWLDDDVVNGPGTADMKGGIAVMLHALLALEQSEHGRSLGYDVMINSDEET
GSLSSAKLIEELANGKYAALTYEPSATPEGTLAHARGGTGNYSLIVKGRSAHAGRNPQDGRNALVAAAALAVGLKDLQTE
DCPVNPAKIEGGAANNVVPDNAVLRFNIRPKEPSAGERFEAGLQGLMAAIRQAHEVSVDLHGGVTRPPKPVDRKAQRLFD
LVRDCGAELGQHIDWQSTGGVCDGNNIAACGVPVVDTMGVRGGKIHSPDEFMIVPSLSERAALSALVLHRLASGDEL

Sequences:

>Translated_397_residues
MKPSYLESIDQAAMCEQALAWSAVNSGTGNLDGLKTVAGMLADAFAALPGEVELRDPAPVTAISADGQEFDKQHGQHLVV
RVRPDAERRVVLTGHMDTVFPIDHPFQENSWLDDDVVNGPGTADMKGGIAVMLHALLALEQSEHGRSLGYDVMINSDEET
GSLSSAKLIEELANGKYAALTYEPSATPEGTLAHARGGTGNYSLIVKGRSAHAGRNPQDGRNALVAAAALAVGLKDLQTE
DCPVNPAKIEGGAANNVVPDNAVLRFNIRPKEPSAGERFEAGLQGLMAAIRQAHEVSVDLHGGVTRPPKPVDRKAQRLFD
LVRDCGAELGQHIDWQSTGGVCDGNNIAACGVPVVDTMGVRGGKIHSPDEFMIVPSLSERAALSALVLHRLASGDEL
>Mature_397_residues
MKPSYLESIDQAAMCEQALAWSAVNSGTGNLDGLKTVAGMLADAFAALPGEVELRDPAPVTAISADGQEFDKQHGQHLVV
RVRPDAERRVVLTGHMDTVFPIDHPFQENSWLDDDVVNGPGTADMKGGIAVMLHALLALEQSEHGRSLGYDVMINSDEET
GSLSSAKLIEELANGKYAALTYEPSATPEGTLAHARGGTGNYSLIVKGRSAHAGRNPQDGRNALVAAAALAVGLKDLQTE
DCPVNPAKIEGGAANNVVPDNAVLRFNIRPKEPSAGERFEAGLQGLMAAIRQAHEVSVDLHGGVTRPPKPVDRKAQRLFD
LVRDCGAELGQHIDWQSTGGVCDGNNIAACGVPVVDTMGVRGGKIHSPDEFMIVPSLSERAALSALVLHRLASGDEL

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 41902; Mature: 41902

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPSYLESIDQAAMCEQALAWSAVNSGTGNLDGLKTVAGMLADAFAALPGEVELRDPAPV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCE
TAISADGQEFDKQHGQHLVVRVRPDAERRVVLTGHMDTVFPIDHPFQENSWLDDDVVNGP
EEEECCCHHHHHCCCCEEEEEECCCCCCEEEEEECCCEEECCCCCCCCCCCCCCCCCCCC
GTADMKGGIAVMLHALLALEQSEHGRSLGYDVMINSDEETGSLSSAKLIEELANGKYAAL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEE
TYEPSATPEGTLAHARGGTGNYSLIVKGRSAHAGRNPQDGRNALVAAAALAVGLKDLQTE
EECCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
DCPVNPAKIEGGAANNVVPDNAVLRFNIRPKEPSAGERFEAGLQGLMAAIRQAHEVSVDL
CCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEE
HGGVTRPPKPVDRKAQRLFDLVRDCGAELGQHIDWQSTGGVCDGNNIAACGVPVVDTMGV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHCCC
RGGKIHSPDEFMIVPSLSERAALSALVLHRLASGDEL
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKPSYLESIDQAAMCEQALAWSAVNSGTGNLDGLKTVAGMLADAFAALPGEVELRDPAPV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCE
TAISADGQEFDKQHGQHLVVRVRPDAERRVVLTGHMDTVFPIDHPFQENSWLDDDVVNGP
EEEECCCHHHHHCCCCEEEEEECCCCCCEEEEEECCCEEECCCCCCCCCCCCCCCCCCCC
GTADMKGGIAVMLHALLALEQSEHGRSLGYDVMINSDEETGSLSSAKLIEELANGKYAAL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEE
TYEPSATPEGTLAHARGGTGNYSLIVKGRSAHAGRNPQDGRNALVAAAALAVGLKDLQTE
EECCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
DCPVNPAKIEGGAANNVVPDNAVLRFNIRPKEPSAGERFEAGLQGLMAAIRQAHEVSVDL
CCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEE
HGGVTRPPKPVDRKAQRLFDLVRDCGAELGQHIDWQSTGGVCDGNNIAACGVPVVDTMGV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHCCC
RGGKIHSPDEFMIVPSLSERAALSALVLHRLASGDEL
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]