Click here to switch to the map view.

The map label for this gene is atpH [H]

Identifier: 85374580

GI number: 85374580

Start: 1786402

End: 1787028

Strand: Direct

Name: atpH [H]

Synonym: ELI_08765

Alternate gene names: 85374580

Gene position: 1786402-1787028 (Clockwise)

Preceding gene: 85374578

Following gene: 85374581

Centisome position: 58.52

GC content: 63.8

Gene sequence:

>627_bases
GTGCCATTCCAGCATCCCAATCGGCCCAAGCGATGCATCGTTATTCTCCGGATCCAAGAGGACCTCAAGCGCGTGGATAT
TTCCGCCGGTATTCAGGCTAGCCTGGCAGGCCGTTATGCCTCGGCCCTGTTCGAACTCGCCGCCGAAGAAGGTGTCGTGA
CCGCGGTCGAGTCCGACCTCGACAAGCTTCACGCCGCACTCGGCGAATCGGACGATCTCAAGGCCGTGACCAACAATCCC
GAAATCAGCCGCAAGGACCAGGCCTCCGCCATCGAAGGCGTCGCAGGCGTCCTGGGCCTCTCGCCGCTGACCACGAAGTT
CCTCGGCACGCTGGCCGCCAATCGCCGCCTGTCGAAGCTCGGCGACATGATCCGCGCCTTCCGCACGATCGCGGCGGCGC
AGCGCGGCGAAGTCACCGCTGACGTCGTCAGCGCGCATCCGCTCAAGGACGATCAGCTCGAATCGCTCAAGACCAAGCTG
ACCGCGCGCGAAGGCCGCACCGTGAAACTTTCCCCGACCGTCGATCCTGACCTGCTCGGTGGCCTCGTCGTCACCATCGG
CTCCAAGCGCATCGACGGTTCGATCCGCACCCGCTTGAATACCCTCGCCAACGCGATGAAAGGCTAA

Upstream 100 bases:

>100_bases
GCGCCAGAGACCAATCTCGCAACATCCGTTCCAAAAACCGCATCGGACTCGGCTTGCCTTCGGGCATACCCGATGCTAGG
CGCGCGCCAGCTTTGCCGGG

Downstream 100 bases:

>100_bases
GGCACAATGGACATCCGCGCCGCAGAAATCTCCAAGGTCATCAAGGACCAGATCGCCAACTTCGGCACCGAAGCGCAGGT
CAGCGAAGTCGGTTCCGTTC

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MPFQHPNRPKRCIVILRIQEDLKRVDISAGIQASLAGRYASALFELAAEEGVVTAVESDLDKLHAALGESDDLKAVTNNP
EISRKDQASAIEGVAGVLGLSPLTTKFLGTLAANRRLSKLGDMIRAFRTIAAAQRGEVTADVVSAHPLKDDQLESLKTKL
TAREGRTVKLSPTVDPDLLGGLVVTIGSKRIDGSIRTRLNTLANAMKG

Sequences:

>Translated_208_residues
MPFQHPNRPKRCIVILRIQEDLKRVDISAGIQASLAGRYASALFELAAEEGVVTAVESDLDKLHAALGESDDLKAVTNNP
EISRKDQASAIEGVAGVLGLSPLTTKFLGTLAANRRLSKLGDMIRAFRTIAAAQRGEVTADVVSAHPLKDDQLESLKTKL
TAREGRTVKLSPTVDPDLLGGLVVTIGSKRIDGSIRTRLNTLANAMKG
>Mature_207_residues
PFQHPNRPKRCIVILRIQEDLKRVDISAGIQASLAGRYASALFELAAEEGVVTAVESDLDKLHAALGESDDLKAVTNNPE
ISRKDQASAIEGVAGVLGLSPLTTKFLGTLAANRRLSKLGDMIRAFRTIAAAQRGEVTADVVSAHPLKDDQLESLKTKLT
AREGRTVKLSPTVDPDLLGGLVVTIGSKRIDGSIRTRLNTLANAMKG

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction [H]

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family [H]

Homologues:

Organism=Homo sapiens, GI4502303, Length=175, Percent_Identity=35.4285714285714, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1790173, Length=185, Percent_Identity=25.9459459459459, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71984717, Length=172, Percent_Identity=32.5581395348837, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71984710, Length=172, Percent_Identity=32.5581395348837, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320504, Length=176, Percent_Identity=28.4090909090909, Blast_Score=75, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24647054, Length=177, Percent_Identity=38.9830508474576, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24647056, Length=124, Percent_Identity=41.1290322580645, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000711 [H]

Pfam domain/function: PF00213 OSCP [H]

EC number: 3.6.3.14

Molecular weight: Translated: 22217; Mature: 22086

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFQHPNRPKRCIVILRIQEDLKRVDISAGIQASLAGRYASALFELAAEEGVVTAVESDL
CCCCCCCCCCEEEEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DKLHAALGESDDLKAVTNNPEISRKDQASAIEGVAGVLGLSPLTTKFLGTLAANRRLSKL
HHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
GDMIRAFRTIAAAQRGEVTADVVSAHPLKDDQLESLKTKLTAREGRTVKLSPTVDPDLLG
HHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHH
GLVVTIGSKRIDGSIRTRLNTLANAMKG
HHHEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PFQHPNRPKRCIVILRIQEDLKRVDISAGIQASLAGRYASALFELAAEEGVVTAVESDL
CCCCCCCCCEEEEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DKLHAALGESDDLKAVTNNPEISRKDQASAIEGVAGVLGLSPLTTKFLGTLAANRRLSKL
HHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
GDMIRAFRTIAAAQRGEVTADVVSAHPLKDDQLESLKTKLTAREGRTVKLSPTVDPDLLG
HHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHH
GLVVTIGSKRIDGSIRTRLNTLANAMKG
HHHEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA