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The map label for this gene is yciL [C]

Identifier: 85374350

GI number: 85374350

Start: 1577121

End: 1577921

Strand: Direct

Name: yciL [C]

Synonym: ELI_07615

Alternate gene names: 85374350

Gene position: 1577121-1577921 (Clockwise)

Preceding gene: 85374348

Following gene: 85374351

Centisome position: 51.67

GC content: 66.54

Gene sequence:

>801_bases
ATGGCAGCCCCACCCAAACAGAACCATGAACGCAGCCCAGACCGCCCCGATGGCGACCGCATCGCCAAGCTGCTCGCCCG
CGCCGGTGTCGCGAGCCGCCGCGAGGTCGAGCGCATGATCACCGACGGGCGCGTCGCGCTGCACGGCAAGCCGGTCGAGA
CGCCCGCGACCTTCCTCGAAAGCCTGCGCGGCGTGACGGTGGACGGCAAGCCCGTCGGCAAGGCCGAGCCGACGCGGCTG
TTCGCTTTCAACAAACCGACCGGGCTGCTGACGGCCGAGAACGACCCGAAGGGCCGCGCCACAATCTATGACGCGCTCAA
AAACGCCTTGCCCAAGGATGCGGGCCGCGTGATGCCGATCGGGCGGCTCGACTTCAACACGGAAGGCCTGCTGCTGCTCA
CCAACGATGGCGGGCTCAAACGCCGGATGGAACTGCCTTCGTCGGGCATCCCCCGCACCTACCGCGCGCGCGCTTTCGGA
GACATCACGCAGGAACAGCTCGAAAGCCTGATCGAAGGGATCGAAATCGACGGGGTCCGTTACGGCCGGATCGACGCCAA
TCTGGAGCAGAAGACGAAGAGCGCCGGGGGCCGCAATCAGTGGATCGAGATGACGATCACCGAGGGCAAGAACCGCGAAG
TGCGGCGCGTGCTCGAACATTTCGGACTGGAAGTGAGCCGCCTGATGCGTGTCGCCTATGGCCCGTTCCAGCTCGGCGAC
CTGCCGCGCGGCCAAGCCGTCGAAATCCGCAAGGGCGATCTCGGCCGGTTCCTGAGCACGCTCAAGAAGGAGGGCGCGTG
A

Upstream 100 bases:

>100_bases
GTCACTCCCTTTGCGCCGACACTAGCGCAGCCACGCGCTGTGGGAAGCCCCGACCATCCGCGCTTCCACCGCAACGTTCG
TCCGTGTAGAGGCGCTCACC

Downstream 100 bases:

>100_bases
GGATCATCGCCGGCGAATGGCGCGGGCGGAAACTGGTCGCACCGAGGGGCGACGGCACCCGCCCGACCGCAGACCGGACG
CGCGAGACTTTGTTCTCGAT

Product: hypothetical protein

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MAAPPKQNHERSPDRPDGDRIAKLLARAGVASRREVERMITDGRVALHGKPVETPATFLESLRGVTVDGKPVGKAEPTRL
FAFNKPTGLLTAENDPKGRATIYDALKNALPKDAGRVMPIGRLDFNTEGLLLLTNDGGLKRRMELPSSGIPRTYRARAFG
DITQEQLESLIEGIEIDGVRYGRIDANLEQKTKSAGGRNQWIEMTITEGKNREVRRVLEHFGLEVSRLMRVAYGPFQLGD
LPRGQAVEIRKGDLGRFLSTLKKEGA

Sequences:

>Translated_266_residues
MAAPPKQNHERSPDRPDGDRIAKLLARAGVASRREVERMITDGRVALHGKPVETPATFLESLRGVTVDGKPVGKAEPTRL
FAFNKPTGLLTAENDPKGRATIYDALKNALPKDAGRVMPIGRLDFNTEGLLLLTNDGGLKRRMELPSSGIPRTYRARAFG
DITQEQLESLIEGIEIDGVRYGRIDANLEQKTKSAGGRNQWIEMTITEGKNREVRRVLEHFGLEVSRLMRVAYGPFQLGD
LPRGQAVEIRKGDLGRFLSTLKKEGA
>Mature_265_residues
AAPPKQNHERSPDRPDGDRIAKLLARAGVASRREVERMITDGRVALHGKPVETPATFLESLRGVTVDGKPVGKAEPTRLF
AFNKPTGLLTAENDPKGRATIYDALKNALPKDAGRVMPIGRLDFNTEGLLLLTNDGGLKRRMELPSSGIPRTYRARAFGD
ITQEQLESLIEGIEIDGVRYGRIDANLEQKTKSAGGRNQWIEMTITEGKNREVRRVLEHFGLEVSRLMRVAYGPFQLGDL
PRGQAVEIRKGDLGRFLSTLKKEGA

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=242, Percent_Identity=41.3223140495868, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI87081838, Length=185, Percent_Identity=34.0540540540541, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790453, Length=236, Percent_Identity=30.9322033898305, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788510, Length=227, Percent_Identity=28.1938325991189, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 29376; Mature: 29245

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPPKQNHERSPDRPDGDRIAKLLARAGVASRREVERMITDGRVALHGKPVETPATFLE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCEEEECCCCCCCHHHHHH
SLRGVTVDGKPVGKAEPTRLFAFNKPTGLLTAENDPKGRATIYDALKNALPKDAGRVMPI
HHCCCEECCCCCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCC
GRLDFNTEGLLLLTNDGGLKRRMELPSSGIPRTYRARAFGDITQEQLESLIEGIEIDGVR
CCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCEE
YGRIDANLEQKTKSAGGRNQWIEMTITEGKNREVRRVLEHFGLEVSRLMRVAYGPFQLGD
ECCCCCCHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
LPRGQAVEIRKGDLGRFLSTLKKEGA
CCCCCEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AAPPKQNHERSPDRPDGDRIAKLLARAGVASRREVERMITDGRVALHGKPVETPATFLE
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCEEEECCCCCCCHHHHHH
SLRGVTVDGKPVGKAEPTRLFAFNKPTGLLTAENDPKGRATIYDALKNALPKDAGRVMPI
HHCCCEECCCCCCCCCCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCC
GRLDFNTEGLLLLTNDGGLKRRMELPSSGIPRTYRARAFGDITQEQLESLIEGIEIDGVR
CCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCEE
YGRIDANLEQKTKSAGGRNQWIEMTITEGKNREVRRVLEHFGLEVSRLMRVAYGPFQLGD
ECCCCCCHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
LPRGQAVEIRKGDLGRFLSTLKKEGA
CCCCCEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA