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The map label for this gene is accD

Identifier: 85374347

GI number: 85374347

Start: 1572883

End: 1573731

Strand: Direct

Name: accD

Synonym: ELI_07600

Alternate gene names: 85374347

Gene position: 1572883-1573731 (Clockwise)

Preceding gene: 85374346

Following gene: 85374348

Centisome position: 51.53

GC content: 65.25

Gene sequence:

>849_bases
ATGAACTGGTTCACACGCGTTCGCAATTCGCTGGGCTTCGGCCCCAAGCGCACCACCGACAAGGATCTGTGGGTCAAGTG
CCCCTCCTGCGCGGAGATGCTCTTTGCGCAGGAATACGAGGAGAATGCACAGGTCTGCCCGCGCTGCGACCACCATGGCC
GTATTTCGGCGGACGAGCGGCTGCGGCAATTGCTCGACGAGGGCTATGAAGTGCTGCCGCAGCCCGAAGTCGCCGAGGAT
CCGCTCAAGTTCAGGGATTCGAAGAAATATACCGACCGCCTGAAGCAGGCGCGCGCGAAAAACCCGCATGCCGATGCCTT
CACGGTCGGTTCGGGCGCGATCGACGGGCACCATGCGGTCGTGGGCGTCCAGGACTTCGGCTTCATGGGCGGTTCGATGG
GCATGGCAGTAGGCACCGCGTTCTGCGCCGGGGCCGAGCGGGCGCTGCGCCGCAAGTGCGGCTATATCGTCGTGACGGCC
GCAGGCGGCGCGCGGATGCAGGAGGGCATTCTCAGCCTGATGCAGATGCCCAAGGCGACCGTCATGACCCGCCGCCTGCG
TGAAGCCGGCCTGCCTTATATCGTCGTGCTGACCGACCCGACCACCGGCGGCGTCACCGCCAGCTACGCCATGCTGGGCG
ACGTCCATATCGCCGAGCCGGGCGCGCTGATCGGCTTTGCCGGCCAGCGGGTGATCCAGGATACGATCCGCGAGCAATTG
CCCGATGGCTTCCAGCGCGCGGAGTATTTGCACAAGCACGGCATGGTCGATCGCGTGGTGCACCGGCACCAGTTGAAGCA
CGAACTGGCGACGCTGCTGGGTTATCTGCAGCCCGCCGAGGCTGCCTAA

Upstream 100 bases:

>100_bases
GAACTGGTCGGCGAATTTGGCACCGAGGCCCCGGCCAAGCTACAAGAGCTGACCAAGGCACTGGCTGACGCGGTCCATTC
CGCACGCTAAGGACGACAAC

Downstream 100 bases:

>100_bases
TGAACATCGTCATCCCAGCGAAAGCTGGGATCTCGCTCCACCAGGATCGACGCAAGTGGCGAGAGACCCCAGCTTTCGCT
GGGGTGACGAGGTAGCCATG

Product: acetyl-CoA carboxylase beta subunit

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNWFTRVRNSLGFGPKRTTDKDLWVKCPSCAEMLFAQEYEENAQVCPRCDHHGRISADERLRQLLDEGYEVLPQPEVAED
PLKFRDSKKYTDRLKQARAKNPHADAFTVGSGAIDGHHAVVGVQDFGFMGGSMGMAVGTAFCAGAERALRRKCGYIVVTA
AGGARMQEGILSLMQMPKATVMTRRLREAGLPYIVVLTDPTTGGVTASYAMLGDVHIAEPGALIGFAGQRVIQDTIREQL
PDGFQRAEYLHKHGMVDRVVHRHQLKHELATLLGYLQPAEAA

Sequences:

>Translated_282_residues
MNWFTRVRNSLGFGPKRTTDKDLWVKCPSCAEMLFAQEYEENAQVCPRCDHHGRISADERLRQLLDEGYEVLPQPEVAED
PLKFRDSKKYTDRLKQARAKNPHADAFTVGSGAIDGHHAVVGVQDFGFMGGSMGMAVGTAFCAGAERALRRKCGYIVVTA
AGGARMQEGILSLMQMPKATVMTRRLREAGLPYIVVLTDPTTGGVTASYAMLGDVHIAEPGALIGFAGQRVIQDTIREQL
PDGFQRAEYLHKHGMVDRVVHRHQLKHELATLLGYLQPAEAA
>Mature_282_residues
MNWFTRVRNSLGFGPKRTTDKDLWVKCPSCAEMLFAQEYEENAQVCPRCDHHGRISADERLRQLLDEGYEVLPQPEVAED
PLKFRDSKKYTDRLKQARAKNPHADAFTVGSGAIDGHHAVVGVQDFGFMGGSMGMAVGTAFCAGAERALRRKCGYIVVTA
AGGARMQEGILSLMQMPKATVMTRRLREAGLPYIVVLTDPTTGGVTASYAMLGDVHIAEPGALIGFAGQRVIQDTIREQL
PDGFQRAEYLHKHGMVDRVVHRHQLKHELATLLGYLQPAEAA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=277, Percent_Identity=49.0974729241877, Blast_Score=280, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_ERYLH (Q2N9M9)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458409.1
- STRING:   Q2N9M9
- GeneID:   3871538
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_07600
- NMPDR:   fig|314225.3.peg.1522
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   AGEAFIT
- PhylomeDB:   Q2N9M9
- ProtClustDB:   CLSK835193
- BioCyc:   ELIT314225:ELI_07600-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 31092; Mature: 31092

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWFTRVRNSLGFGPKRTTDKDLWVKCPSCAEMLFAQEYEENAQVCPRCDHHGRISADER
CCHHHHHHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LRQLLDEGYEVLPQPEVAEDPLKFRDSKKYTDRLKQARAKNPHADAFTVGSGAIDGHHAV
HHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEE
VGVQDFGFMGGSMGMAVGTAFCAGAERALRRKCGYIVVTAAGGARMQEGILSLMQMPKAT
EEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCHHH
VMTRRLREAGLPYIVVLTDPTTGGVTASYAMLGDVHIAEPGALIGFAGQRVIQDTIREQL
HHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCEEECCCCCEEEHHHHHHHHHHHHHHC
PDGFQRAEYLHKHGMVDRVVHRHQLKHELATLLGYLQPAEAA
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNWFTRVRNSLGFGPKRTTDKDLWVKCPSCAEMLFAQEYEENAQVCPRCDHHGRISADER
CCHHHHHHHHCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LRQLLDEGYEVLPQPEVAEDPLKFRDSKKYTDRLKQARAKNPHADAFTVGSGAIDGHHAV
HHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEE
VGVQDFGFMGGSMGMAVGTAFCAGAERALRRKCGYIVVTAAGGARMQEGILSLMQMPKAT
EEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCHHH
VMTRRLREAGLPYIVVLTDPTTGGVTASYAMLGDVHIAEPGALIGFAGQRVIQDTIREQL
HHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCEEECCCCCEEEHHHHHHHHHHHHHHC
PDGFQRAEYLHKHGMVDRVVHRHQLKHELATLLGYLQPAEAA
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA