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The map label for this gene is trpD

Identifier: 85374129

GI number: 85374129

Start: 1350108

End: 1351100

Strand: Direct

Name: trpD

Synonym: ELI_06510

Alternate gene names: 85374129

Gene position: 1350108-1351100 (Clockwise)

Preceding gene: 85374128

Following gene: 85374130

Centisome position: 44.23

GC content: 66.47

Gene sequence:

>993_bases
ATGAAAACCCTCCCCCTCGCCGTCCCGCATATGAGCCAGGACGAGGCCGAAGAGGTGTTCGGCTGGATCCTCGACGGCGA
AGCCTCGGAAGAGGAAATCGCGCGCTTCCTGCTCGCCATGACCGAGCGGAGCGAGACGGCGGACGAAATCGCCGGGGCGG
CGCGCGCCTTGCGGGATCGGCTCATCCCCGTCGAAGCGCCCGAAGGTGCCGTCGATTGCTGCGGCACCGGCGGCGACGGG
CATCACACGCTCAATGTCTCGACTGCCGTGAGCCTGGTGGTAGCCGCGGCAGGCGTGCCGGTCGCCAAGCACGGCAACCG
CGCGGCGTCGTCGAAATCCGGCGCTGCCGACACGCTCGAAGCGCTCGGCCTCGACATGGAGGCCGTTGGTCGCACGGCGG
AGAAGACACTCGCCGAGATCGGCATCTGTTTTCTGTTCGCCAAGAACCACCACCCGGCGATGGGCCGTATCCAGCCCATT
CGCCAGCGCCTCGGCAAACGCACGATCTTCAACCTGATGGGCCCGCTGTCCAACCCCGCGGGGGTAAAGCGCCAGCTGAT
CGGAATCGCGCGGCCCGGCTACGTCCCGATCTATGCCGAAGCCAAGGCCAAGCTGGGCACGGAGCGGACATACATCGTTT
CCGGCGACGAAGGGCTGGATGAGCTCAGCCTTGCCGGCGGCAACGAGCTGGCCGACGTCTGCGGAAACGAGTTCGAGATG
CGCCGCGTCTATGCCGAGATGATCGGCCTGCCGCATGCGCCGGTGGAGGCCATTCGAGGCGGCGATGCAGCCCACAATGC
CATGGCGCTGAAGGCCCTGCTCGAAGGCACCCCCGGCCCCTATCGGGATGCCGTCGTCTTCAACGCGGCTGCGACGCTGA
TGGCAGCAGGTGCGGTCGAAGATTGGGAGGTCGGCGCGGCGATGGCAGTGGAATCGCTCGATAGCGGCAAGGCCAACGAA
TTGCTGGGCAAATGGATCGAGATGGCGGTCTAG

Upstream 100 bases:

>100_bases
TCCACCCGGAAAGCATCGCCACCGAGCACGGCCATGACCTGCTTGCCAACTTCCTGTCGCTGTGCGGCATTTCCCCTGCC
CGCACAGAAAAGGCACCCGC

Downstream 100 bases:

>100_bases
TGTAAAGCCCCCCTTCCGTTCGCCCTGAGCCTGTCGGAAGCGAAGCTGACGCAAAGCGTCTACGGCTGTCGTTTCCTGGA
ACACGCCCACCAGAAGTAAG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKTLPLAVPHMSQDEAEEVFGWILDGEASEEEIARFLLAMTERSETADEIAGAARALRDRLIPVEAPEGAVDCCGTGGDG
HHTLNVSTAVSLVVAAAGVPVAKHGNRAASSKSGAADTLEALGLDMEAVGRTAEKTLAEIGICFLFAKNHHPAMGRIQPI
RQRLGKRTIFNLMGPLSNPAGVKRQLIGIARPGYVPIYAEAKAKLGTERTYIVSGDEGLDELSLAGGNELADVCGNEFEM
RRVYAEMIGLPHAPVEAIRGGDAAHNAMALKALLEGTPGPYRDAVVFNAAATLMAAGAVEDWEVGAAMAVESLDSGKANE
LLGKWIEMAV

Sequences:

>Translated_330_residues
MKTLPLAVPHMSQDEAEEVFGWILDGEASEEEIARFLLAMTERSETADEIAGAARALRDRLIPVEAPEGAVDCCGTGGDG
HHTLNVSTAVSLVVAAAGVPVAKHGNRAASSKSGAADTLEALGLDMEAVGRTAEKTLAEIGICFLFAKNHHPAMGRIQPI
RQRLGKRTIFNLMGPLSNPAGVKRQLIGIARPGYVPIYAEAKAKLGTERTYIVSGDEGLDELSLAGGNELADVCGNEFEM
RRVYAEMIGLPHAPVEAIRGGDAAHNAMALKALLEGTPGPYRDAVVFNAAATLMAAGAVEDWEVGAAMAVESLDSGKANE
LLGKWIEMAV
>Mature_330_residues
MKTLPLAVPHMSQDEAEEVFGWILDGEASEEEIARFLLAMTERSETADEIAGAARALRDRLIPVEAPEGAVDCCGTGGDG
HHTLNVSTAVSLVVAAAGVPVAKHGNRAASSKSGAADTLEALGLDMEAVGRTAEKTLAEIGICFLFAKNHHPAMGRIQPI
RQRLGKRTIFNLMGPLSNPAGVKRQLIGIARPGYVPIYAEAKAKLGTERTYIVSGDEGLDELSLAGGNELADVCGNEFEM
RRVYAEMIGLPHAPVEAIRGGDAAHNAMALKALLEGTPGPYRDAVVFNAAATLMAAGAVEDWEVGAAMAVESLDSGKANE
LLGKWIEMAV

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=311, Percent_Identity=38.2636655948553, Blast_Score=179, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6320561, Length=326, Percent_Identity=32.2085889570552, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_ERYLH (Q2NA97)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_458191.1
- HSSP:   P50384
- ProteinModelPortal:   Q2NA97
- SMR:   Q2NA97
- STRING:   Q2NA97
- GeneID:   3870308
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_06510
- NMPDR:   fig|314225.3.peg.1753
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   ATPSQMG
- PhylomeDB:   Q2NA97
- ProtClustDB:   PRK00188
- BioCyc:   ELIT314225:ELI_06510-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 34677; Mature: 34677

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLPLAVPHMSQDEAEEVFGWILDGEASEEEIARFLLAMTERSETADEIAGAARALRDR
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
LIPVEAPEGAVDCCGTGGDGHHTLNVSTAVSLVVAAAGVPVAKHGNRAASSKSGAADTLE
CCCCCCCCCCCEECCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
ALGLDMEAVGRTAEKTLAEIGICFLFAKNHHPAMGRIQPIRQRLGKRTIFNLMGPLSNPA
HHCCCHHHHCCHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
GVKRQLIGIARPGYVPIYAEAKAKLGTERTYIVSGDEGLDELSLAGGNELADVCGNEFEM
HHHHHHHHHCCCCCEEEEECCHHCCCCCEEEEEECCCCCHHHHCCCCCHHHHHCCCHHHH
RRVYAEMIGLPHAPVEAIRGGDAAHNAMALKALLEGTPGPYRDAVVFNAAATLMAAGAVE
HHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
DWEVGAAMAVESLDSGKANELLGKWIEMAV
CHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKTLPLAVPHMSQDEAEEVFGWILDGEASEEEIARFLLAMTERSETADEIAGAARALRDR
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
LIPVEAPEGAVDCCGTGGDGHHTLNVSTAVSLVVAAAGVPVAKHGNRAASSKSGAADTLE
CCCCCCCCCCCEECCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
ALGLDMEAVGRTAEKTLAEIGICFLFAKNHHPAMGRIQPIRQRLGKRTIFNLMGPLSNPA
HHCCCHHHHCCHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
GVKRQLIGIARPGYVPIYAEAKAKLGTERTYIVSGDEGLDELSLAGGNELADVCGNEFEM
HHHHHHHHHCCCCCEEEEECCHHCCCCCEEEEEECCCCCHHHHCCCCCHHHHHCCCHHHH
RRVYAEMIGLPHAPVEAIRGGDAAHNAMALKALLEGTPGPYRDAVVFNAAATLMAAGAVE
HHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
DWEVGAAMAVESLDSGKANELLGKWIEMAV
CHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA