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The map label for this gene is tauD [H]

Identifier: 85374096

GI number: 85374096

Start: 1319944

End: 1320789

Strand: Direct

Name: tauD [H]

Synonym: ELI_06345

Alternate gene names: 85374096

Gene position: 1319944-1320789 (Clockwise)

Preceding gene: 85374095

Following gene: 85374098

Centisome position: 43.24

GC content: 62.65

Gene sequence:

>846_bases
ATGAGCATGATCGTCGAGCCGTCCGGACAGGCCTGCGGCGCCACGATACGCGGCGTCGATCTGTCCGGAAAGCTCGATGA
CGCGCTGATTACCGATGTCCGATCGGCTTGGCTCACGCACCGCGTGCTCGCCTTTGCCGACCAGTCAATGGACGACGACG
CGCTGGAGCGCTTCACCCTCGCCATGGGCGGTTTCGGCGAAGACCCGTTCTTCGACCCGATCCCCGGGCGCGGCAACATT
GCGGCGATCCTGCGCGAACCCGACGAGAAGGCACCCCTGTTCGCGGAAAACTGGCATAGCGACTGGAGCTTCCTCTCCCA
CCCGCCTGCCGGAACGTGCCTGCTGGCGATCGAAATCCCGCCCGTCGGCGGCGATACATTGTTTGCCGACCAGATTGCAG
CCTTTGCTGCGCTGTCGGACGAGCGGAAAGATCAACTACGTGCACTCACTGCGATTCACAGCGCGAAACTCGCCTATGCG
CCGGACGGAACCTACGGCGAGAAAGACGCCGCGGCAGGACGCTCCATGGCGATCCGCCCCGATGAGAGCGCCAATGCGAT
GCAAACACATCCCCTGATCCAGGCTCATCCCGAAACCGGCGAAGAAGCGATCTTTTCCACGCTCGGTTACATCATCGGGA
TCGAAGGGATGGCACAGGCCGAAGCAATCGCTCTGCTATCAGAATTGGCCCAATGGCAGTCGCGCGACGAGTTCGTCTAT
CGCCACCACTGGGAACCCGACATGCTGGTGCTTTGGGACAATCGCAGTGTCCTCCACAAGGCGACCGGCGGCTACGAAGG
CCACCGCCGCGAACTGCACCGCACCACTATTGCTGCCACGCCGTAG

Upstream 100 bases:

>100_bases
AAGAGGCCGTCGTCGAAGGTATGGTCGGTCGCGGGGCCGAAGAGACAGCGCCCGACCCCACCATGGATCGCGACAGCAAC
GAGGGCGAGGCACCGCCCGA

Downstream 100 bases:

>100_bases
CGAGCCGTTCGCCGCGCAGGGTCTGGACGACGCCTGTCGCGATCAGGAACTGTCCCAGATAATAAAGCGGCCAGATCAAC
AGGCCCGGCAGCGTGTCCAG

Product: alpha-ketoglutarate-dependent taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSMIVEPSGQACGATIRGVDLSGKLDDALITDVRSAWLTHRVLAFADQSMDDDALERFTLAMGGFGEDPFFDPIPGRGNI
AAILREPDEKAPLFAENWHSDWSFLSHPPAGTCLLAIEIPPVGGDTLFADQIAAFAALSDERKDQLRALTAIHSAKLAYA
PDGTYGEKDAAAGRSMAIRPDESANAMQTHPLIQAHPETGEEAIFSTLGYIIGIEGMAQAEAIALLSELAQWQSRDEFVY
RHHWEPDMLVLWDNRSVLHKATGGYEGHRRELHRTTIAATP

Sequences:

>Translated_281_residues
MSMIVEPSGQACGATIRGVDLSGKLDDALITDVRSAWLTHRVLAFADQSMDDDALERFTLAMGGFGEDPFFDPIPGRGNI
AAILREPDEKAPLFAENWHSDWSFLSHPPAGTCLLAIEIPPVGGDTLFADQIAAFAALSDERKDQLRALTAIHSAKLAYA
PDGTYGEKDAAAGRSMAIRPDESANAMQTHPLIQAHPETGEEAIFSTLGYIIGIEGMAQAEAIALLSELAQWQSRDEFVY
RHHWEPDMLVLWDNRSVLHKATGGYEGHRRELHRTTIAATP
>Mature_280_residues
SMIVEPSGQACGATIRGVDLSGKLDDALITDVRSAWLTHRVLAFADQSMDDDALERFTLAMGGFGEDPFFDPIPGRGNIA
AILREPDEKAPLFAENWHSDWSFLSHPPAGTCLLAIEIPPVGGDTLFADQIAAFAALSDERKDQLRALTAIHSAKLAYAP
DGTYGEKDAAAGRSMAIRPDESANAMQTHPLIQAHPETGEEAIFSTLGYIIGIEGMAQAEAIALLSELAQWQSRDEFVYR
HHWEPDMLVLWDNRSVLHKATGGYEGHRRELHRTTIAATP

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=275, Percent_Identity=32, Blast_Score=137, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6322971, Length=286, Percent_Identity=29.020979020979, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 30661; Mature: 30529

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMIVEPSGQACGATIRGVDLSGKLDDALITDVRSAWLTHRVLAFADQSMDDDALERFTL
CCEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AMGGFGEDPFFDPIPGRGNIAAILREPDEKAPLFAENWHSDWSFLSHPPAGTCLLAIEIP
HHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHCCCCCCCHHCCCCCCEEEEEEEEC
PVGGDTLFADQIAAFAALSDERKDQLRALTAIHSAKLAYAPDGTYGEKDAAAGRSMAIRP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHCCCCCEEECC
DESANAMQTHPLIQAHPETGEEAIFSTLGYIIGIEGMAQAEAIALLSELAQWQSRDEFVY
CCCCCCHHHCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEE
RHHWEPDMLVLWDNRSVLHKATGGYEGHRRELHRTTIAATP
EECCCCCEEEEECCCCEEECCCCCCCHHHHHHHHHEEECCC
>Mature Secondary Structure 
SMIVEPSGQACGATIRGVDLSGKLDDALITDVRSAWLTHRVLAFADQSMDDDALERFTL
CEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AMGGFGEDPFFDPIPGRGNIAAILREPDEKAPLFAENWHSDWSFLSHPPAGTCLLAIEIP
HHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHCCCCCCCHHCCCCCCEEEEEEEEC
PVGGDTLFADQIAAFAALSDERKDQLRALTAIHSAKLAYAPDGTYGEKDAAAGRSMAIRP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHCCCCCEEECC
DESANAMQTHPLIQAHPETGEEAIFSTLGYIIGIEGMAQAEAIALLSELAQWQSRDEFVY
CCCCCCHHHCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEE
RHHWEPDMLVLWDNRSVLHKATGGYEGHRRELHRTTIAATP
EECCCCCEEEEECCCCEEECCCCCCCHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]