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The map label for this gene is 85373423

Identifier: 85373423

GI number: 85373423

Start: 628517

End: 629599

Strand: Direct

Name: 85373423

Synonym: ELI_02980

Alternate gene names: NA

Gene position: 628517-629599 (Clockwise)

Preceding gene: 85373422

Following gene: 85373425

Centisome position: 20.59

GC content: 63.43

Gene sequence:

>1083_bases
TTGCCGCTCAAGGGTGAAATCTCGGCTCAAGCAGGGCGCGAGTTCGATACGAGCAGACTGGACCTGCGGGCGATCATCGA
TCCGCGCGATCTGCGTGTGGACCCGACGCGCCTGTTCCTGGAAACCACGCAGCAGACGCGCCTGGCGATCTGCATTTCGG
ACCCTCACCAACCCGATTGCCCGGTGGTCTATGTCAACCAGGCGTTCCTCGATCTGACCGGCTATGCGCGCGAGGAGATC
GTCGGCAGGAATTGCCGCTTTCTACAGGGCGCGGACACCGATCCCGAACAGGTCCGGAAACTGCGCGAAGGGATTGCGGC
AGAGCGCTATACCGTCGTCGACCTGCTCAACTACAGGAAGGATGGTATCCCGTTCTGGAATGCGGTTCATGTCGGCCCGA
TCTACGGCGAGGACGGCACGTTGCAGTATTTCTACGGCTCGCAATGGGACATTACCGATATCGTCGCGGAGCGCCGCAAA
GCCGAAACGCAGCGCCGGATTGCCGCCGAGCTGCGTCATCGCACCGGCAATATCTTCGCCGTCCTCAACGCCATCATCGG
CCTGACCTCGCGCCGCGAGCGCGACGTATCGGAATTCGCCGATAAACTTTCCGAGAGGGTCAGCGCGCTCGCCTCCGCCC
ACCGCATGACCATCATGGACGAGCCGGACCAGGAAGCGGTCGCGATCGACGATCTCGTCACCGGCGTCATGAAACCCTAT
CGCAACCGCTTCGCCGAGCGGGTGACCACTTCCGGTCCGAAAATCGAGCTGGGGCCGCGCAGCGTCACCGCCCTCGGCCT
CGCCCTGCACGAACTGGCGACCAATGCCGTCAAATACGGCGCGCTGAGCGTCGATGCCGGTCGCGTCGAGATTTCATGGA
GCCGCGAGGACGGCGATGTCACGCTGGTCTGGCAGGAACAGGGCGGGCCGACGGTTTCTCAGGAGCAGTCCGAGCCCGTG
AAGGGCAACGGCACGATGCTGATCGACGGCATGATCGCCAGCCTCACCGGCTCCATCGAGCGCGACTTTGCGGCCGCGGG
TCTTCAGGCGAAGATCACACTGCCCGTGCATCAACCGGAGTGA

Upstream 100 bases:

>100_bases
TGGTATGACGAATACGCGGCGAATCGTGGGGGAAGCGCTCGCGCGTAGCGACTGACATAACGTCGAAGGATCGAACGTGA
CGGACGGTGACGGGCGGGAT

Downstream 100 bases:

>100_bases
TCCGGCGGGAGGCGGTCAGCCCCACTTTCTCGTGCGATACCAGCGGGTTATGACGTATTTTACACCTTGCTCCACCGGTG
TTCCGGCATGCAGGGTGTCT

Product: hypothetical protein

Products: NA

Alternate protein names: EL360-LOV-histidine kinase; EL360-LOV-HK

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MPLKGEISAQAGREFDTSRLDLRAIIDPRDLRVDPTRLFLETTQQTRLAICISDPHQPDCPVVYVNQAFLDLTGYAREEI
VGRNCRFLQGADTDPEQVRKLREGIAAERYTVVDLLNYRKDGIPFWNAVHVGPIYGEDGTLQYFYGSQWDITDIVAERRK
AETQRRIAAELRHRTGNIFAVLNAIIGLTSRRERDVSEFADKLSERVSALASAHRMTIMDEPDQEAVAIDDLVTGVMKPY
RNRFAERVTTSGPKIELGPRSVTALGLALHELATNAVKYGALSVDAGRVEISWSREDGDVTLVWQEQGGPTVSQEQSEPV
KGNGTMLIDGMIASLTGSIERDFAAAGLQAKITLPVHQPE

Sequences:

>Translated_360_residues
MPLKGEISAQAGREFDTSRLDLRAIIDPRDLRVDPTRLFLETTQQTRLAICISDPHQPDCPVVYVNQAFLDLTGYAREEI
VGRNCRFLQGADTDPEQVRKLREGIAAERYTVVDLLNYRKDGIPFWNAVHVGPIYGEDGTLQYFYGSQWDITDIVAERRK
AETQRRIAAELRHRTGNIFAVLNAIIGLTSRRERDVSEFADKLSERVSALASAHRMTIMDEPDQEAVAIDDLVTGVMKPY
RNRFAERVTTSGPKIELGPRSVTALGLALHELATNAVKYGALSVDAGRVEISWSREDGDVTLVWQEQGGPTVSQEQSEPV
KGNGTMLIDGMIASLTGSIERDFAAAGLQAKITLPVHQPE
>Mature_359_residues
PLKGEISAQAGREFDTSRLDLRAIIDPRDLRVDPTRLFLETTQQTRLAICISDPHQPDCPVVYVNQAFLDLTGYAREEIV
GRNCRFLQGADTDPEQVRKLREGIAAERYTVVDLLNYRKDGIPFWNAVHVGPIYGEDGTLQYFYGSQWDITDIVAERRKA
ETQRRIAAELRHRTGNIFAVLNAIIGLTSRRERDVSEFADKLSERVSALASAHRMTIMDEPDQEAVAIDDLVTGVMKPYR
NRFAERVTTSGPKIELGPRSVTALGLALHELATNAVKYGALSVDAGRVEISWSREDGDVTLVWQEQGGPTVSQEQSEPVK
GNGTMLIDGMIASLTGSIERDFAAAGLQAKITLPVHQPE

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain

Homologues:

Organism=Homo sapiens, GI27886667, Length=145, Percent_Identity=29.6551724137931, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI38569493, Length=95, Percent_Identity=37.8947368421053, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17136946, Length=129, Percent_Identity=28.6821705426357, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LVHK1_ERYLH (Q2NCA3)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457485.1
- ProteinModelPortal:   Q2NCA3
- STRING:   Q2NCA3
- GeneID:   3870323
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_02980
- NMPDR:   fig|314225.3.peg.2485
- eggNOG:   COG3920
- HOGENOM:   HBG543880
- OMA:   RLAICIS
- ProtClustDB:   PRK13559
- BioCyc:   ELIT314225:ELI_02980-MONOMER
- GO:   GO:0009405
- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR011102
- Gene3D:   G3DSA:3.30.565.10
- SMART:   SM00911
- SMART:   SM00086
- SMART:   SM00091
- TIGRFAMs:   TIGR00229

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; SSF55874 ATP_bd_ATPase

EC number: =2.7.13.3

Molecular weight: Translated: 39976; Mature: 39844

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50113 PAC; PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKGEISAQAGREFDTSRLDLRAIIDPRDLRVDPTRLFLETTQQTRLAICISDPHQPDC
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECHHHHEEEECCCCEEEEEECCCCCCCC
PVVYVNQAFLDLTGYAREEIVGRNCRFLQGADTDPEQVRKLREGIAAERYTVVDLLNYRK
CEEEECHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
DGIPFWNAVHVGPIYGEDGTLQYFYGSQWDITDIVAERRKAETQRRIAAELRHRTGNIFA
CCCCCCCEEEECCEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VLNAIIGLTSRRERDVSEFADKLSERVSALASAHRMTIMDEPDQEAVAIDDLVTGVMKPY
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHH
RNRFAERVTTSGPKIELGPRSVTALGLALHELATNAVKYGALSVDAGRVEISWSREDGDV
HHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCEEEECCCEEEEEEECCCCCE
TLVWQEQGGPTVSQEQSEPVKGNGTMLIDGMIASLTGSIERDFAAAGLQAKITLPVHQPE
EEEEECCCCCCCCCCCCCCCCCCCCEEECCHHHHHHCCHHHHHHHCCCEEEEEECCCCCC
>Mature Secondary Structure 
PLKGEISAQAGREFDTSRLDLRAIIDPRDLRVDPTRLFLETTQQTRLAICISDPHQPDC
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECHHHHEEEECCCCEEEEEECCCCCCCC
PVVYVNQAFLDLTGYAREEIVGRNCRFLQGADTDPEQVRKLREGIAAERYTVVDLLNYRK
CEEEECHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
DGIPFWNAVHVGPIYGEDGTLQYFYGSQWDITDIVAERRKAETQRRIAAELRHRTGNIFA
CCCCCCCEEEECCEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
VLNAIIGLTSRRERDVSEFADKLSERVSALASAHRMTIMDEPDQEAVAIDDLVTGVMKPY
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHH
RNRFAERVTTSGPKIELGPRSVTALGLALHELATNAVKYGALSVDAGRVEISWSREDGDV
HHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCEEEECCCEEEEEEECCCCCE
TLVWQEQGGPTVSQEQSEPVKGNGTMLIDGMIASLTGSIERDFAAAGLQAKITLPVHQPE
EEEEECCCCCCCCCCCCCCCCCCCCEEECCHHHHHHCCHHHHHHHCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA