Click here to switch to the map view.

The map label for this gene is lysK

Identifier: 85373422

GI number: 85373422

Start: 626831

End: 628471

Strand: Direct

Name: lysK

Synonym: ELI_02975

Alternate gene names: 85373422

Gene position: 626831-628471 (Clockwise)

Preceding gene: 85373421

Following gene: 85373423

Centisome position: 20.54

GC content: 62.71

Gene sequence:

>1641_bases
ATGAGCATGCAAGACCTGATGAACGCCGCCCGCGTCTCCAAAGCCTGGCCCTTCCAGGAGGCGCAGCGGCTGCTCAAGCG
CTATCCGGACGGTAAACCCGGTGGCGAACCGGTGCTCTTCGAAACGGGCTATGGCCCCAGCGGTCTGCCGCATATCGGCA
CCTTCCAGGAGGTGCTGCGCACCACGCTGGTGCGGCGGGCCTATGAAGCGATCATCGGCGCGCGGCCCGAAGACGGCAAG
ACGCGCCTGGTCGCCTTCAGCGATGACATGGACGGCCTGCGCAAGGTGCCCGACAATATCGACCGCAAGGATGTGCTGGA
GGCGAACCTGCACAAGCCGCTTAGCCGCATCCCGAGCCCGTTCAGCAACGAGCACGACAGCTACGCCGCGCACAACAATG
CGAAGCTGCGCGAATTCCTCGACCGCTTCTGCTTCGACTACGATTTCGTCGCCTCGTCCGACATGTACAATTCGGGGCAG
TTCGACGAAGCGCTGAAGCAGGTCCTGCGCAAGAACCAGGACATTCTCGACATCATGCTGCCGACATTGCGCGCCGAGCG
GGCGGCAACCTATTCGCCGGTTCTCCCGATCAGCCCGGAAACGGGCCGCGTGCTGCAGGTGCCGGTCGAAGTCGTCGATG
CCGAGACAGGGATCGTACGCTTCACCGACGAGGACGGAACAGTGGTCGAGCAGTCGGCGCTCGGCGGCATGGCCAAGCTG
CAATGGAAAGTCGACTGGGCGATGCGCTGGTACGCGCTCGGCGTCGATTACGAGATGTACGGCAAGGACCTGACCGACAG
CGGCGTGCAGTCGGGCCGCATCGTTAAGGTGCTCGGCGGGCGCAAGCCGGAAGGGCTGATCTATGAGCTGTTCCTCGACG
AGAAAGGCGAGAAAATCTCCAAGTCCAAAGGCAACGGCCTGACGATCGAGGAATGGCTGACCTATGGCACCGAAGAGAGC
CTGGGCTTTTACATCTTCCCCAATCCCAAGAGCGCCAAGCAATTGCATGTCGGCGTGATTCCGCGCGCGGTCGACGATTA
CTGGCAATTCCGCGAGCGGATCCCGGAGCAGGAACTCGAAAAGCAGCTCGGCAATCCGGCGTGGAACCTGCTGCGCGTCA
ACGGCGATTGGCCGGAGGGGGACAGGGTGGCAGAAGCGCCGGGGGCGGGGGACAGCCTGCCGGTGACCTATGGCCTGCTG
CTCAATCTCGCGAGCGTGCTGGGGGCCGAAGCGACCGAGCAGAACCTCGCCGACTATCTCGACACCTATCTCGATGGTGC
CGAGCGCGGGCCGGAACTCGATGCGCTGATCGCCTGCGCGGTCGCCTATACGCGCGACTACATCGTGCCGACCCTCAACA
AGCGCGCGCCGGCGCCCAACGAAGCCGCGGCCTTGCACGAACTCGATACTTTCCTCGCCGAAGCCGATCCGGCGATGAGT
GCGGAAGACTTGCAGACGCAGGTCTACGAGATTGGAAAGAAAGAGGAATACGGCTTCGAGAGCTTGCGCGACTGGTTCAA
GGCGCTGTATCAGACACTGCTCGGAACCGACCAAGGTCCACGTATGGGCAGTTTCATAAAGCTGTATGGTATGACGAATA
CGCGGCGAATCGTGGGGGAAGCGCTCGCGCGTAGCGACTGA

Upstream 100 bases:

>100_bases
ATCCAACAGGGTGACAGGGTGTAACCTGTGTCACCCGGCCGGGCACCGCCACCGCCGTTTCGCACTTGCAACACTTGCAA
GGCTCACGCAAAGGCGGCCC

Downstream 100 bases:

>100_bases
CATAACGTCGAAGGATCGAACGTGACGGACGGTGACGGGCGGGATTTGCCGCTCAAGGGTGAAATCTCGGCTCAAGCAGG
GCGCGAGTTCGATACGAGCA

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MSMQDLMNAARVSKAWPFQEAQRLLKRYPDGKPGGEPVLFETGYGPSGLPHIGTFQEVLRTTLVRRAYEAIIGARPEDGK
TRLVAFSDDMDGLRKVPDNIDRKDVLEANLHKPLSRIPSPFSNEHDSYAAHNNAKLREFLDRFCFDYDFVASSDMYNSGQ
FDEALKQVLRKNQDILDIMLPTLRAERAATYSPVLPISPETGRVLQVPVEVVDAETGIVRFTDEDGTVVEQSALGGMAKL
QWKVDWAMRWYALGVDYEMYGKDLTDSGVQSGRIVKVLGGRKPEGLIYELFLDEKGEKISKSKGNGLTIEEWLTYGTEES
LGFYIFPNPKSAKQLHVGVIPRAVDDYWQFRERIPEQELEKQLGNPAWNLLRVNGDWPEGDRVAEAPGAGDSLPVTYGLL
LNLASVLGAEATEQNLADYLDTYLDGAERGPELDALIACAVAYTRDYIVPTLNKRAPAPNEAAALHELDTFLAEADPAMS
AEDLQTQVYEIGKKEEYGFESLRDWFKALYQTLLGTDQGPRMGSFIKLYGMTNTRRIVGEALARSD

Sequences:

>Translated_546_residues
MSMQDLMNAARVSKAWPFQEAQRLLKRYPDGKPGGEPVLFETGYGPSGLPHIGTFQEVLRTTLVRRAYEAIIGARPEDGK
TRLVAFSDDMDGLRKVPDNIDRKDVLEANLHKPLSRIPSPFSNEHDSYAAHNNAKLREFLDRFCFDYDFVASSDMYNSGQ
FDEALKQVLRKNQDILDIMLPTLRAERAATYSPVLPISPETGRVLQVPVEVVDAETGIVRFTDEDGTVVEQSALGGMAKL
QWKVDWAMRWYALGVDYEMYGKDLTDSGVQSGRIVKVLGGRKPEGLIYELFLDEKGEKISKSKGNGLTIEEWLTYGTEES
LGFYIFPNPKSAKQLHVGVIPRAVDDYWQFRERIPEQELEKQLGNPAWNLLRVNGDWPEGDRVAEAPGAGDSLPVTYGLL
LNLASVLGAEATEQNLADYLDTYLDGAERGPELDALIACAVAYTRDYIVPTLNKRAPAPNEAAALHELDTFLAEADPAMS
AEDLQTQVYEIGKKEEYGFESLRDWFKALYQTLLGTDQGPRMGSFIKLYGMTNTRRIVGEALARSD
>Mature_545_residues
SMQDLMNAARVSKAWPFQEAQRLLKRYPDGKPGGEPVLFETGYGPSGLPHIGTFQEVLRTTLVRRAYEAIIGARPEDGKT
RLVAFSDDMDGLRKVPDNIDRKDVLEANLHKPLSRIPSPFSNEHDSYAAHNNAKLREFLDRFCFDYDFVASSDMYNSGQF
DEALKQVLRKNQDILDIMLPTLRAERAATYSPVLPISPETGRVLQVPVEVVDAETGIVRFTDEDGTVVEQSALGGMAKLQ
WKVDWAMRWYALGVDYEMYGKDLTDSGVQSGRIVKVLGGRKPEGLIYELFLDEKGEKISKSKGNGLTIEEWLTYGTEESL
GFYIFPNPKSAKQLHVGVIPRAVDDYWQFRERIPEQELEKQLGNPAWNLLRVNGDWPEGDRVAEAPGAGDSLPVTYGLLL
NLASVLGAEATEQNLADYLDTYLDGAERGPELDALIACAVAYTRDYIVPTLNKRAPAPNEAAALHELDTFLAEADPAMSA
EDLQTQVYEIGKKEEYGFESLRDWFKALYQTLLGTDQGPRMGSFIKLYGMTNTRRIVGEALARSD

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 61011; Mature: 60880

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMQDLMNAARVSKAWPFQEAQRLLKRYPDGKPGGEPVLFETGYGPSGLPHIGTFQEVLR
CCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
TTLVRRAYEAIIGARPEDGKTRLVAFSDDMDGLRKVPDNIDRKDVLEANLHKPLSRIPSP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
FSNEHDSYAAHNNAKLREFLDRFCFDYDFVASSDMYNSGQFDEALKQVLRKNQDILDIML
CCCCCCCHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
PTLRAERAATYSPVLPISPETGRVLQVPVEVVDAETGIVRFTDEDGTVVEQSALGGMAKL
HHHHHHHCCCCCCCCCCCCCCCCEEECCHHEEECCCCEEEEECCCCCEEEHHHCCCCEEE
QWKVDWAMRWYALGVDYEMYGKDLTDSGVQSGRIVKVLGGRKPEGLIYELFLDEKGEKIS
EEEEEEEEEEEEECCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCHHH
KSKGNGLTIEEWLTYGTEESLGFYIFPNPKSAKQLHVGVIPRAVDDYWQFRERIPEQELE
CCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHH
KQLGNPAWNLLRVNGDWPEGDRVAEAPGAGDSLPVTYGLLLNLASVLGAEATEQNLADYL
HHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
DTYLDGAERGPELDALIACAVAYTRDYIVPTLNKRAPAPNEAAALHELDTFLAEADPAMS
HHHHCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
AEDLQTQVYEIGKKEEYGFESLRDWFKALYQTLLGTDQGPRMGSFIKLYGMTNTRRIVGE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHH
ALARSD
HHHCCC
>Mature Secondary Structure 
SMQDLMNAARVSKAWPFQEAQRLLKRYPDGKPGGEPVLFETGYGPSGLPHIGTFQEVLR
CHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
TTLVRRAYEAIIGARPEDGKTRLVAFSDDMDGLRKVPDNIDRKDVLEANLHKPLSRIPSP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCC
FSNEHDSYAAHNNAKLREFLDRFCFDYDFVASSDMYNSGQFDEALKQVLRKNQDILDIML
CCCCCCCHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
PTLRAERAATYSPVLPISPETGRVLQVPVEVVDAETGIVRFTDEDGTVVEQSALGGMAKL
HHHHHHHCCCCCCCCCCCCCCCCEEECCHHEEECCCCEEEEECCCCCEEEHHHCCCCEEE
QWKVDWAMRWYALGVDYEMYGKDLTDSGVQSGRIVKVLGGRKPEGLIYELFLDEKGEKIS
EEEEEEEEEEEEECCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCHHH
KSKGNGLTIEEWLTYGTEESLGFYIFPNPKSAKQLHVGVIPRAVDDYWQFRERIPEQELE
CCCCCCCCHHHHHHCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHH
KQLGNPAWNLLRVNGDWPEGDRVAEAPGAGDSLPVTYGLLLNLASVLGAEATEQNLADYL
HHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
DTYLDGAERGPELDALIACAVAYTRDYIVPTLNKRAPAPNEAAALHELDTFLAEADPAMS
HHHHCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
AEDLQTQVYEIGKKEEYGFESLRDWFKALYQTLLGTDQGPRMGSFIKLYGMTNTRRIVGE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHH
ALARSD
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA