Click here to switch to the map view.

The map label for this gene is murG

Identifier: 85373186

GI number: 85373186

Start: 403018

End: 404214

Strand: Direct

Name: murG

Synonym: ELI_01795

Alternate gene names: 85373186

Gene position: 403018-404214 (Clockwise)

Preceding gene: 85373185

Following gene: 85373187

Centisome position: 13.2

GC content: 67.08

Gene sequence:

>1197_bases
ATGACGGGCGCCAACCGACATTACGTTCTCGCCGCCGGCGGGACCGGGGGGCACTTGCTCCCCGCTTTCGCGCTTGCCGC
AGAACTCGACCGGCGCGGCCACCATGTCGCGCTGATCACCGACGAGCGCGGCGCGAAGATCCCGGGCAAGCCCGATTTCC
TGCCCGCACATGTCATCCCCGCCGGGCGCTTCGGCAAGAACCCGCTGCGCTGGGTGGGGGGACTTCGCGCGGTCTGGAAG
GGCCGCGAAATGGCCAAGCGGCTGTTCGAAAGCTTCCAGCCGAGCGCCGTCGTCGGTTTCGGCGGCTATCCCGCGCTTCC
CGCCATGCTGGCGGCTTCCAGGGAAGACATCCCCAGCATCATTCACGAACAAAACGCGGTACTGGGCCGGGTCAATCGCC
TGCAGGCTGGCCGGGTCAGCGCGATCGCGACCGCCTATCCCGAAATCCAGCGGCTCAAACCCAAGCATGCGGAGAAGATT
CATCTGGTCGGCAATCCCGTCCGCGCCGGCGTTCTGAGCCTGCGCGACGAGCCGTTTCCGCCATTCACCGAAGACGGCCT
GCTGAAGGTGCTCGTGACGGGCGGCAGCCAGGGCGCGAGCGTGTTGTCGCAGATCGTGCCCGATGGTCTCGCCATGCTCC
CCCCGGCGCTGCGCCAGCGGCTGCAAGTGACGCAGCAATGCCGCCCCGAAGACCTCGACACGGTGCGCGAACGTTACAAA
ACGCACGACATCCCTGCTGAGCTCGGATCTTATTTCGAGGACATGGCTGCGCGGCTCGCCGATGCGCATCTCTTCATCGG
GCGCGCAGGCGCCTCGACCATCGCCGAATTGACCGCCGTGGGTCGTCCCGCGATCCTCGTGCCGCTGCCGATTGCGACCG
ACGACCACCAGGCGCACAACACGCGCGAAGTCGTCAAGGCCGGCGGCGCGCGGATGATCCGGCAGGAGAAGTTCACACCT
AAGGAACTCGCCAAGCAGATTCAGGCGCTCGGCCAGCGGCCTGACACGCTTGCCACGGCTGCCCATGCGGCGTGGAACTG
CGGTCGGCCCAAGGCGGTGGAGGACCTCGCCGATCTCGTCGAAAGCTTCGGTGGGGCGGACATGATGGATGTCATCAAGG
TCGGCGGCAACAATGCCCGCGCCGCGTCGCAAGGCGTCGCCGTCGGGCAGGGTGCGGCGAAGGAACGAGCCGAATGA

Upstream 100 bases:

>100_bases
TGACCATCGGCCTGTTGCTGGCGCTGACCCGCCGCAACCCGTTTCTGACGCGCGAAACCCCGGGTCTGCGCGCACTGCTG
AGCGACAAGGAGAAAGGCGC

Downstream 100 bases:

>100_bases
GGGGCGTTCCGACCGATATCGGGGTGATCCATTTCGTCGGCATCGGCGGCATCGGCATGTCCGGCATCGCCGAGGTGATG
CACAACCTCGGCTACCAGGT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTGANRHYVLAAGGTGGHLLPAFALAAELDRRGHHVALITDERGAKIPGKPDFLPAHVIPAGRFGKNPLRWVGGLRAVWK
GREMAKRLFESFQPSAVVGFGGYPALPAMLAASREDIPSIIHEQNAVLGRVNRLQAGRVSAIATAYPEIQRLKPKHAEKI
HLVGNPVRAGVLSLRDEPFPPFTEDGLLKVLVTGGSQGASVLSQIVPDGLAMLPPALRQRLQVTQQCRPEDLDTVRERYK
THDIPAELGSYFEDMAARLADAHLFIGRAGASTIAELTAVGRPAILVPLPIATDDHQAHNTREVVKAGGARMIRQEKFTP
KELAKQIQALGQRPDTLATAAHAAWNCGRPKAVEDLADLVESFGGADMMDVIKVGGNNARAASQGVAVGQGAAKERAE

Sequences:

>Translated_398_residues
MTGANRHYVLAAGGTGGHLLPAFALAAELDRRGHHVALITDERGAKIPGKPDFLPAHVIPAGRFGKNPLRWVGGLRAVWK
GREMAKRLFESFQPSAVVGFGGYPALPAMLAASREDIPSIIHEQNAVLGRVNRLQAGRVSAIATAYPEIQRLKPKHAEKI
HLVGNPVRAGVLSLRDEPFPPFTEDGLLKVLVTGGSQGASVLSQIVPDGLAMLPPALRQRLQVTQQCRPEDLDTVRERYK
THDIPAELGSYFEDMAARLADAHLFIGRAGASTIAELTAVGRPAILVPLPIATDDHQAHNTREVVKAGGARMIRQEKFTP
KELAKQIQALGQRPDTLATAAHAAWNCGRPKAVEDLADLVESFGGADMMDVIKVGGNNARAASQGVAVGQGAAKERAE
>Mature_397_residues
TGANRHYVLAAGGTGGHLLPAFALAAELDRRGHHVALITDERGAKIPGKPDFLPAHVIPAGRFGKNPLRWVGGLRAVWKG
REMAKRLFESFQPSAVVGFGGYPALPAMLAASREDIPSIIHEQNAVLGRVNRLQAGRVSAIATAYPEIQRLKPKHAEKIH
LVGNPVRAGVLSLRDEPFPPFTEDGLLKVLVTGGSQGASVLSQIVPDGLAMLPPALRQRLQVTQQCRPEDLDTVRERYKT
HDIPAELGSYFEDMAARLADAHLFIGRAGASTIAELTAVGRPAILVPLPIATDDHQAHNTREVVKAGGARMIRQEKFTPK
ELAKQIQALGQRPDTLATAAHAAWNCGRPKAVEDLADLVESFGGADMMDVIKVGGNNARAASQGVAVGQGAAKERAE

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=371, Percent_Identity=30.188679245283, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_ERYLH (Q2NCZ0)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457248.1
- ProteinModelPortal:   Q2NCZ0
- STRING:   Q2NCZ0
- GeneID:   3868844
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_01795
- NMPDR:   fig|314225.3.peg.2730
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q2NCZ0
- ProtClustDB:   PRK00726
- BioCyc:   ELIT314225:ELI_01795-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 42510; Mature: 42379

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGANRHYVLAAGGTGGHLLPAFALAAELDRRGHHVALITDERGAKIPGKPDFLPAHVIP
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
AGRFGKNPLRWVGGLRAVWKGREMAKRLFESFQPSAVVGFGGYPALPAMLAASREDIPSI
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCHHHHHHH
IHEQNAVLGRVNRLQAGRVSAIATAYPEIQRLKPKHAEKIHLVGNPVRAGVLSLRDEPFP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCCCC
PFTEDGLLKVLVTGGSQGASVLSQIVPDGLAMLPPALRQRLQVTQQCRPEDLDTVRERYK
CCCCCCEEEEEEECCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHH
THDIPAELGSYFEDMAARLADAHLFIGRAGASTIAELTAVGRPAILVPLPIATDDHQAHN
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
TREVVKAGGARMIRQEKFTPKELAKQIQALGQRPDTLATAAHAAWNCGRPKAVEDLADLV
HHHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
ESFGGADMMDVIKVGGNNARAASQGVAVGQGAAKERAE
HHHCCCCHHHHHHHCCCCCHHHHCCCCCCCCCHHHCCC
>Mature Secondary Structure 
TGANRHYVLAAGGTGGHLLPAFALAAELDRRGHHVALITDERGAKIPGKPDFLPAHVIP
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
AGRFGKNPLRWVGGLRAVWKGREMAKRLFESFQPSAVVGFGGYPALPAMLAASREDIPSI
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCHHHHHHH
IHEQNAVLGRVNRLQAGRVSAIATAYPEIQRLKPKHAEKIHLVGNPVRAGVLSLRDEPFP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCCCC
PFTEDGLLKVLVTGGSQGASVLSQIVPDGLAMLPPALRQRLQVTQQCRPEDLDTVRERYK
CCCCCCEEEEEEECCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHH
THDIPAELGSYFEDMAARLADAHLFIGRAGASTIAELTAVGRPAILVPLPIATDDHQAHN
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
TREVVKAGGARMIRQEKFTPKELAKQIQALGQRPDTLATAAHAAWNCGRPKAVEDLADLV
HHHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
ESFGGADMMDVIKVGGNNARAASQGVAVGQGAAKERAE
HHHCCCCHHHHHHHCCCCCHHHHCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA