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The map label for this gene is mrdB [H]

Identifier: 85373185

GI number: 85373185

Start: 401792

End: 403021

Strand: Direct

Name: mrdB [H]

Synonym: ELI_01790

Alternate gene names: 85373185

Gene position: 401792-403021 (Clockwise)

Preceding gene: 85373184

Following gene: 85373186

Centisome position: 13.16

GC content: 63.5

Gene sequence:

>1230_bases
ATGAATTCAACGCAGCAGCCCTATGTGCCCGGTGTCGGCGAGCGCATGGCGGGGGCGGAGCTACGCTCATCCTCGGCGAT
GTCCGAGCTGCGGATCTGGTGGCGCGAAGTCGACCGCGTCGTGCTGTTTCTCGTCCTCGCGCTGATCACGATCGGTACGA
TCGCCGTTGCTGCCGCCTCGCCGTCCAGCGCGCGCCGACTATCGACCGCCTCGGAGAAACTGCCAGACCTGTACTTCTAC
TGGGCCCATCTGCGCTGGCAGTTCGTCGGCATCGTCGTCCTTCTCGGCGCATCCTTCCTGAGCCGCGACAATGCGCGGCG
ACTGGGCATCCTGATCGCCGCGGGCATGCTCGGCGCGCTCTTCCTCGTGCCGCTGATCGGCTACGAAGTGAACGGGGCGA
AGCGCTGGATCCGCTTCGGTCTGGGTTTCCAACCGTCCGAATTTCTCAAGCCCGGCTTTGCCATCGCCATGGCCTGGATC
CTGTCGTGGCGGCTCAAGGATCCGAACCTGCCGGTGCTTGCCATCGTCACTGGCCTCATGGGCATCATTGCCCTGCTGCT
GATGCTGCAACCCAACCTCGGCGCGACGATCCTGTTCGGCGGAGTCTGGTTCGTGCTGGTGCTGCTCTCCGGCGTGTCGG
CCAAACGGATCGCCGGTATCATCGCAGCCGGGGTAGGCGCGCTACTGGCGGCCTATTTCCTCTACGACAACGCCCGGCAT
CGCATCGATGATTTTCTGGGTGGAGGGACCGCCTTCGACCAGGTCGACCTGGCGCAAAAGACGCTGCTCGGTGGCGGCTG
GAGCGGGACGGGTTTCTGGCTCGGCCTCAAGAAGATGAGCCTGCCCGAAGCTCACACGGATTACGTGTTCTCCGTCATCG
GCGAGGAGTTCGGTCTGGTCCTGTGCGCGCTCGTCGTCATTCTCTATCTCGCCATCATCGCGCGCGTTCTGGTGCGGCTG
GCGGACGAGGAGAACCTCTTTGCGCTTCTCGCTGCGGCGGGTCTTATCACGCAGTTCGGCGGGCAGGCCTTCATCAATAT
CCTCGTCAATTTGCAGCTTTTTCCGTCGAAAGGCATGACCCTGCCGCTCGTCAGCTATGGCGGCTCATCGACCATTGCCG
TATGCCTGACCATCGGCCTGTTGCTGGCGCTGACCCGCCGCAACCCGTTTCTGACGCGCGAAACCCCGGGTCTGCGCGCA
CTGCTGAGCGACAAGGAGAAAGGCGCATGA

Upstream 100 bases:

>100_bases
AGCACTTCCGCCAGTTGGTCGGCGCGCTCTCGGGCTGCGACATCGATGATATTTGCGAGCCGACGCTGGCAGGCAATGGC
GACATGAAGGGTGAAGCGGC

Downstream 100 bases:

>100_bases
CGGGCGCCAACCGACATTACGTTCTCGCCGCCGGCGGGACCGGGGGGCACTTGCTCCCCGCTTTCGCGCTTGCCGCAGAA
CTCGACCGGCGCGGCCACCA

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MNSTQQPYVPGVGERMAGAELRSSSAMSELRIWWREVDRVVLFLVLALITIGTIAVAAASPSSARRLSTASEKLPDLYFY
WAHLRWQFVGIVVLLGASFLSRDNARRLGILIAAGMLGALFLVPLIGYEVNGAKRWIRFGLGFQPSEFLKPGFAIAMAWI
LSWRLKDPNLPVLAIVTGLMGIIALLLMLQPNLGATILFGGVWFVLVLLSGVSAKRIAGIIAAGVGALLAAYFLYDNARH
RIDDFLGGGTAFDQVDLAQKTLLGGGWSGTGFWLGLKKMSLPEAHTDYVFSVIGEEFGLVLCALVVILYLAIIARVLVRL
ADEENLFALLAAAGLITQFGGQAFINILVNLQLFPSKGMTLPLVSYGGSSTIAVCLTIGLLLALTRRNPFLTRETPGLRA
LLSDKEKGA

Sequences:

>Translated_409_residues
MNSTQQPYVPGVGERMAGAELRSSSAMSELRIWWREVDRVVLFLVLALITIGTIAVAAASPSSARRLSTASEKLPDLYFY
WAHLRWQFVGIVVLLGASFLSRDNARRLGILIAAGMLGALFLVPLIGYEVNGAKRWIRFGLGFQPSEFLKPGFAIAMAWI
LSWRLKDPNLPVLAIVTGLMGIIALLLMLQPNLGATILFGGVWFVLVLLSGVSAKRIAGIIAAGVGALLAAYFLYDNARH
RIDDFLGGGTAFDQVDLAQKTLLGGGWSGTGFWLGLKKMSLPEAHTDYVFSVIGEEFGLVLCALVVILYLAIIARVLVRL
ADEENLFALLAAAGLITQFGGQAFINILVNLQLFPSKGMTLPLVSYGGSSTIAVCLTIGLLLALTRRNPFLTRETPGLRA
LLSDKEKGA
>Mature_409_residues
MNSTQQPYVPGVGERMAGAELRSSSAMSELRIWWREVDRVVLFLVLALITIGTIAVAAASPSSARRLSTASEKLPDLYFY
WAHLRWQFVGIVVLLGASFLSRDNARRLGILIAAGMLGALFLVPLIGYEVNGAKRWIRFGLGFQPSEFLKPGFAIAMAWI
LSWRLKDPNLPVLAIVTGLMGIIALLLMLQPNLGATILFGGVWFVLVLLSGVSAKRIAGIIAAGVGALLAAYFLYDNARH
RIDDFLGGGTAFDQVDLAQKTLLGGGWSGTGFWLGLKKMSLPEAHTDYVFSVIGEEFGLVLCALVVILYLAIIARVLVRL
ADEENLFALLAAAGLITQFGGQAFINILVNLQLFPSKGMTLPLVSYGGSSTIAVCLTIGLLLALTRRNPFLTRETPGLRA
LLSDKEKGA

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=365, Percent_Identity=30.1369863013699, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786853, Length=277, Percent_Identity=31.0469314079422, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44122; Mature: 44122

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure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EEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]