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The map label for this gene is clpP [H]

Identifier: 84622589

GI number: 84622589

Start: 1016778

End: 1017404

Strand: Direct

Name: clpP [H]

Synonym: XOO_0932

Alternate gene names: 84622589

Gene position: 1016778-1017404 (Clockwise)

Preceding gene: 84622588

Following gene: 84622590

Centisome position: 20.58

GC content: 61.08

Gene sequence:

>627_bases
ATGAGCATTGTGACCAAAGCCCTGAACCTGGTGCCCATGGTGGTCGAGCAGACCAGCCGTGGCGAGCGTGCGTACGACAT
CTACTCGCGTCTGCTGAAGGAGCGTCTGATCTTCCTGGTCGGTCCGATCGACGACCATATGGCCAACGTGATCGTAGCCC
AGTTGCTGTTCCTGGAAGCGGATAACCCGGAAAAGGACATCAGCATCTACATCAATTCGCCTGGTGGCGTGGTCACCGCC
GGCATGGCGATCTACGACACCATGCAGTACATCAAGCCAGATGTGAGCACCATCTGCGTCGGCCAGGCCGCCTCGATGGG
TGCGCTGCTGCTGGCCTCGGGTGCGGCGGGCAAGCGGTACGCGCTGCCGAATTCGCGCGTGATGATCCATCAACCGCTGG
GCGGCTTCCAGGGCCAGGCGACCGATATCGACATCCACGCCCGCGAGATCCTGACCCTGCGTTCGCGCTTGAACGAGATC
CTCGCCAAGCACACTGGTCAGTCGCTGGAGACCATCGCACGCGATACCGAACGCGACAACTTCAAGAGCGCAGTTGATGC
CCAGGCGTATGGCTTGGTGGATCAGGTGCTGGAGCGTCGTCCGGAAGAGTCGATCCAGCCGTCTTGA

Upstream 100 bases:

>100_bases
GCGTCTGATCCGGCAGTAAGAGAAGAACCGCGCCCAGCGTCAGGGGTGCGGATGTCGAACACGGGCAGCGGCACAGGCCG
CTGCCACAACAGGAAGACTG

Downstream 100 bases:

>100_bases
TCGCAGATCGTTGAAATTGCAGGAAAAACCGGCAGGGTCGGGCGGGGCGAATGTCCTCCCGACCCTGTGCTATTCTCGAA
ATCGAACCCCCGTGCATCGG

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MSIVTKALNLVPMVVEQTSRGERAYDIYSRLLKERLIFLVGPIDDHMANVIVAQLLFLEADNPEKDISIYINSPGGVVTA
GMAIYDTMQYIKPDVSTICVGQAASMGALLLASGAAGKRYALPNSRVMIHQPLGGFQGQATDIDIHAREILTLRSRLNEI
LAKHTGQSLETIARDTERDNFKSAVDAQAYGLVDQVLERRPEESIQPS

Sequences:

>Translated_208_residues
MSIVTKALNLVPMVVEQTSRGERAYDIYSRLLKERLIFLVGPIDDHMANVIVAQLLFLEADNPEKDISIYINSPGGVVTA
GMAIYDTMQYIKPDVSTICVGQAASMGALLLASGAAGKRYALPNSRVMIHQPLGGFQGQATDIDIHAREILTLRSRLNEI
LAKHTGQSLETIARDTERDNFKSAVDAQAYGLVDQVLERRPEESIQPS
>Mature_207_residues
SIVTKALNLVPMVVEQTSRGERAYDIYSRLLKERLIFLVGPIDDHMANVIVAQLLFLEADNPEKDISIYINSPGGVVTAG
MAIYDTMQYIKPDVSTICVGQAASMGALLLASGAAGKRYALPNSRVMIHQPLGGFQGQATDIDIHAREILTLRSRLNEIL
AKHTGQSLETIARDTERDNFKSAVDAQAYGLVDQVLERRPEESIQPS

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=199, Percent_Identity=60.8040201005025, Blast_Score=258, Evalue=2e-69,
Organism=Escherichia coli, GI1786641, Length=193, Percent_Identity=75.6476683937824, Blast_Score=318, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17538017, Length=186, Percent_Identity=54.8387096774194, Blast_Score=218, Evalue=1e-57,
Organism=Drosophila melanogaster, GI20129427, Length=197, Percent_Identity=60.4060913705584, Blast_Score=258, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 22796; Mature: 22665

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00381 CLP_PROTEASE_SER ; PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVTKALNLVPMVVEQTSRGERAYDIYSRLLKERLIFLVGPIDDHMANVIVAQLLFLEA
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHCC
DNPEKDISIYINSPGGVVTAGMAIYDTMQYIKPDVSTICVGQAASMGALLLASGAAGKRY
CCCCCEEEEEEECCCCEEEHHHHHHHHHHHHCCCHHHEECCCCHHHCHHEEECCCCCCEE
ALPNSRVMIHQPLGGFQGQATDIDIHAREILTLRSRLNEILAKHTGQSLETIARDTERDN
ECCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
FKSAVDAQAYGLVDQVLERRPEESIQPS
HHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SIVTKALNLVPMVVEQTSRGERAYDIYSRLLKERLIFLVGPIDDHMANVIVAQLLFLEA
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHCC
DNPEKDISIYINSPGGVVTAGMAIYDTMQYIKPDVSTICVGQAASMGALLLASGAAGKRY
CCCCCEEEEEEECCCCEEEHHHHHHHHHHHHCCCHHHEECCCCHHHCHHEEECCCCCCEE
ALPNSRVMIHQPLGGFQGQATDIDIHAREILTLRSRLNEILAKHTGQSLETIARDTERDN
ECCCCEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHH
FKSAVDAQAYGLVDQVLERRPEESIQPS
HHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA