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The map label for this gene is fabF [H]

Identifier: 84622465

GI number: 84622465

Start: 876457

End: 877692

Strand: Direct

Name: fabF [H]

Synonym: XOO_0808

Alternate gene names: 84622465

Gene position: 876457-877692 (Clockwise)

Preceding gene: 84622464

Following gene: 84622466

Centisome position: 17.74

GC content: 63.75

Gene sequence:

>1236_bases
ATGAGTCGTCGTGTTGTCGTTACCGGCATGGGCATTGTGTCGCCGCTGGGCAATGATCTGGCCACCAGCTGGGATGGAAT
CGTCCACGGCCGCTCGGGCATTGGCCCGATCACGCAGATCGATGCCTCGCAGTTCACCACCAAGATCGCCGGTGAAATCA
AGAATTTCGACCCCACGCTTTTTGTGTCCGCCAAGGACGTCAAGAAGATGGATTCGTTCATCCACTACGGTCTCGGCGCC
TCGTTCATGGCGTTGGACGATTCCGGCCTGGAAATCGACGACAGCAATGCCGAACGCGTGGGCGCCATCCTCGGCTCCGG
CATCGGCGGGCTGCTCGGTATTGAAGAGCAGACCATCAAATTCCATGAGGGCGGCGCGCGCAAGATTTCCCCGTTCTATG
TGCCCAGCACCATCATCAACATGCTGCCTGGCCAGGTGAGCCTGATCAAAGGCCTGAAGGGCCCGACGTTCTCGGCGGTA
TCGGCCTGCGCCACCTCCAACCATTCGATCGGCACCGCGATGCGCATGATCCAGCACGGCGATGCCGATGTGATGCTGGC
CGGCGGCGCCGAGCGCGGGTCGTCGCCGGGTTCGGTGGGCGGCTTCTGCGCGATGAAGGCGATGTCCACCCGCAACGACG
ACCCGACCGGCGCCTCGCGGCCGTGGGACAAGCAGCGCGATGGCTTCGTGCTGGGCGACGGTGCCGGCGTTCTGGTGCTG
GAAGAATACGAACACGCCAAGGCGCGTGGCGCGCGCATCTATGCAGAGCTGGTTGGCTTCGGCGCCAGTTCCGATGCGTT
CCACATGACCGCCCCGAGCGAAGATGGCGAAGGCGCGGCGCGCAGCATGGCCGCGGCGATGCGCGATGCCAAGCTCAATC
CCGAGCAGATCGGTTATCTCAATGCGCACGGCACCTCCACGCCGCTGGGCGATCTGGCCGAAACGATCGCGATGAAGCGC
GCGCTGGGCGATCACGCCTACAAGACCATGGTGAGCTCGACCAAGTCGATGACCGGGCATCTGCTCGGCGCGGCCGGTGG
CGTGGAAGCGATCTTTTCGGTGATGGCGCTGCATACCGGGATCATTCCGCCGACCATCAACCTGGAAGAGCCCAGCGAAG
GCTGCGACCTGGATTACGTGCCGAACGTGGCGCGCGAGGTGCAGGTGGACGCGGTAATGTCCAACGGCTTCGGCTTTGGC
GGCACCAACGGCACGCTGGTGTTCAAGCGCGTCTGA

Upstream 100 bases:

>100_bases
CGCGTCAGACATTCCATGGGGCCGCTGATGCGGCCCTGTGTTTTTCAAGCGTCATCCGCAACCCCCAAGCACCGTCCGTT
ACGTGGTTAGGAGATCTGCA

Downstream 100 bases:

>100_bases
TCCGGCGTACCGGTCGCGTCGCCGGCATGGGCGCGCGATCTACCTGGCCGCGGCATGCACTGCGTGCGGGCTTCCGATGT
TGAATTCGTTGATCAACCGT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSRRVVVTGMGIVSPLGNDLATSWDGIVHGRSGIGPITQIDASQFTTKIAGEIKNFDPTLFVSAKDVKKMDSFIHYGLGA
SFMALDDSGLEIDDSNAERVGAILGSGIGGLLGIEEQTIKFHEGGARKISPFYVPSTIINMLPGQVSLIKGLKGPTFSAV
SACATSNHSIGTAMRMIQHGDADVMLAGGAERGSSPGSVGGFCAMKAMSTRNDDPTGASRPWDKQRDGFVLGDGAGVLVL
EEYEHAKARGARIYAELVGFGASSDAFHMTAPSEDGEGAARSMAAAMRDAKLNPEQIGYLNAHGTSTPLGDLAETIAMKR
ALGDHAYKTMVSSTKSMTGHLLGAAGGVEAIFSVMALHTGIIPPTINLEEPSEGCDLDYVPNVAREVQVDAVMSNGFGFG
GTNGTLVFKRV

Sequences:

>Translated_411_residues
MSRRVVVTGMGIVSPLGNDLATSWDGIVHGRSGIGPITQIDASQFTTKIAGEIKNFDPTLFVSAKDVKKMDSFIHYGLGA
SFMALDDSGLEIDDSNAERVGAILGSGIGGLLGIEEQTIKFHEGGARKISPFYVPSTIINMLPGQVSLIKGLKGPTFSAV
SACATSNHSIGTAMRMIQHGDADVMLAGGAERGSSPGSVGGFCAMKAMSTRNDDPTGASRPWDKQRDGFVLGDGAGVLVL
EEYEHAKARGARIYAELVGFGASSDAFHMTAPSEDGEGAARSMAAAMRDAKLNPEQIGYLNAHGTSTPLGDLAETIAMKR
ALGDHAYKTMVSSTKSMTGHLLGAAGGVEAIFSVMALHTGIIPPTINLEEPSEGCDLDYVPNVAREVQVDAVMSNGFGFG
GTNGTLVFKRV
>Mature_410_residues
SRRVVVTGMGIVSPLGNDLATSWDGIVHGRSGIGPITQIDASQFTTKIAGEIKNFDPTLFVSAKDVKKMDSFIHYGLGAS
FMALDDSGLEIDDSNAERVGAILGSGIGGLLGIEEQTIKFHEGGARKISPFYVPSTIINMLPGQVSLIKGLKGPTFSAVS
ACATSNHSIGTAMRMIQHGDADVMLAGGAERGSSPGSVGGFCAMKAMSTRNDDPTGASRPWDKQRDGFVLGDGAGVLVLE
EYEHAKARGARIYAELVGFGASSDAFHMTAPSEDGEGAARSMAAAMRDAKLNPEQIGYLNAHGTSTPLGDLAETIAMKRA
LGDHAYKTMVSSTKSMTGHLLGAAGGVEAIFSVMALHTGIIPPTINLEEPSEGCDLDYVPNVAREVQVDAVMSNGFGFGG
TNGTLVFKRV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=419, Percent_Identity=47.0167064439141, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI223972627, Length=165, Percent_Identity=51.5151515151515, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI41872631, Length=428, Percent_Identity=24.5327102803738, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1787337, Length=410, Percent_Identity=59.2682926829268, Blast_Score=470, Evalue=1e-134,
Organism=Escherichia coli, GI1788663, Length=420, Percent_Identity=40.2380952380952, Blast_Score=256, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71983541, Length=416, Percent_Identity=37.7403846153846, Blast_Score=248, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI71983535, Length=268, Percent_Identity=42.910447761194, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17550940, Length=364, Percent_Identity=26.6483516483516, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI212642053, Length=376, Percent_Identity=23.936170212766, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=39.4618834080717, Blast_Score=295, Evalue=7e-81,
Organism=Drosophila melanogaster, GI24644341, Length=417, Percent_Identity=42.2062350119904, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI19920632, Length=368, Percent_Identity=25.2717391304348, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI221330659, Length=368, Percent_Identity=25.2717391304348, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24581345, Length=377, Percent_Identity=24.1379310344828, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42846; Mature: 42715

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRVVVTGMGIVSPLGNDLATSWDGIVHGRSGIGPITQIDASQFTTKIAGEIKNFDPTL
CCCEEEEECCCHHHHCCCHHHHCCCCEEECCCCCCCCEECCHHHHHHHHHHHHCCCCCEE
FVSAKDVKKMDSFIHYGLGASFMALDDSGLEIDDSNAERVGAILGSGIGGLLGIEEQTIK
EEEHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHCCCCHHCCCCHHEEE
FHEGGARKISPFYVPSTIINMLPGQVSLIKGLKGPTFSAVSACATSNHSIGTAMRMIQHG
EECCCCCCCCCEECHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCC
DADVMLAGGAERGSSPGSVGGFCAMKAMSTRNDDPTGASRPWDKQRDGFVLGDGAGVLVL
CCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
EEYEHAKARGARIYAELVGFGASSDAFHMTAPSEDGEGAARSMAAAMRDAKLNPEQIGYL
ECCHHHHHHHHHEEEHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHEEEE
NAHGTSTPLGDLAETIAMKRALGDHAYKTMVSSTKSMTGHLLGAAGGVEAIFSVMALHTG
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
IIPPTINLEEPSEGCDLDYVPNVAREVQVDAVMSNGFGFGGTNGTLVFKRV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEHEECCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
SRRVVVTGMGIVSPLGNDLATSWDGIVHGRSGIGPITQIDASQFTTKIAGEIKNFDPTL
CCEEEEECCCHHHHCCCHHHHCCCCEEECCCCCCCCEECCHHHHHHHHHHHHCCCCCEE
FVSAKDVKKMDSFIHYGLGASFMALDDSGLEIDDSNAERVGAILGSGIGGLLGIEEQTIK
EEEHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHCCCCHHCCCCHHEEE
FHEGGARKISPFYVPSTIINMLPGQVSLIKGLKGPTFSAVSACATSNHSIGTAMRMIQHG
EECCCCCCCCCEECHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHCC
DADVMLAGGAERGSSPGSVGGFCAMKAMSTRNDDPTGASRPWDKQRDGFVLGDGAGVLVL
CCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
EEYEHAKARGARIYAELVGFGASSDAFHMTAPSEDGEGAARSMAAAMRDAKLNPEQIGYL
ECCHHHHHHHHHEEEHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHEEEE
NAHGTSTPLGDLAETIAMKRALGDHAYKTMVSSTKSMTGHLLGAAGGVEAIFSVMALHTG
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
IIPPTINLEEPSEGCDLDYVPNVAREVQVDAVMSNGFGFGGTNGTLVFKRV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEHEECCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]