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The map label for this gene is trpE2 [H]

Identifier: 84622466

GI number: 84622466

Start: 877863

End: 879218

Strand: Direct

Name: trpE2 [H]

Synonym: XOO_0809

Alternate gene names: 84622466

Gene position: 877863-879218 (Clockwise)

Preceding gene: 84622465

Following gene: 84622467

Centisome position: 17.77

GC content: 68.88

Gene sequence:

>1356_bases
ATGACGCTGACCCGATCACTGCACGCGGACATCGACCTGCTGGCGCTGCATCGGCTGTCACCGCAACGCTATCCGGCTTT
GCTCGAATCCACCGCTTCCGGCACCGCACACGGTCGTTGGGACGTGCTGCTGCTGGCAGAGGGCGCATGCCTGCGGCTGG
ATCCGGATGGCTGCACGCGCAACGGCGAGGGGCAACTGCTGGAAGCCAGCTTTCTGGGCGCGCTGGATGCCGCGTGGCAG
GCCGAGCGCGTGCCGCACGACGCTGCAAGCCCATGGCCGTTTCGCGGCGGTTGGGCAGTGCTGCTGGATTACGAACTGGC
CGCGCAGGTCGAACCGATTCTGCAGTTGCCCAAACGCACCGATGGCCTGCCCACCGCGCTGGCCTTGCGCGCGCCAGCAG
CGGTGCTGCGCGATCGCGTGCAAGGGCGCTGCGTGGCGCTGGCCGAGCCCGGTCGCGCGGATCTGTTGCAGCAGATCGTT
GACGACGTGGCTGCGTGCTCTGCGCTGCCGCCATTGCCTGACTGGATGGGGCCACGTGCGGTCGAAGAGGATGCGCCAGA
GCGCTTCACCGCTGCAGTGGAGCGCGTGCTCGATTACCTGCGCGCCGGCGATGTGTTCCAGGCCAATATCTCGCGTGCCT
GGCACGCGGCATTCGTCGATGCAGTCGACCCGGCCGCACTGCATGCGCGCCTGCGTGCGGCCAATCCGGCGCCGTTCGCG
GGGCTGTTCGTGGCGGCCGGGCGTGCAGTGGCCAGTTCCTCGCCCGAGCGGCTGGTCTCGGTGCAGGGCGAGGCGGTGCA
GACGCGGCCGATCGCCGGCACCCGCGCGCGCTTTGTCGGCGACGACGATGCCGCGCGCATCCGCGAACTGGTTGGGCATC
CGAAGGAGCGTGCCGAGCACGTGATGCTGATCGATCTGGAGCGCAACGACCTGGGCCGCATCTGCGCGCCGGGCACGGTG
GAAGTGGACGAACTGATGTGCGTGGAGAGCTACGCGCATGTGCATCACATCGTCAGCAACGTGCGCGGGCGCCTGCGCGC
CGGGGTGACGCCCGGCGAGGTGATTGCGGCGGTGTTTCCCGGCGGCACCATTACCGGCTGCCCGAAGGTGCGCTGCATGC
AGATCATCGCCGAGCTCGAACAGACCGCGCGTGGCGCCTACACCGGCGCATTCGGCTGGCTCAATCGCGATGGCGACATG
GATCTGAATATCCTGATCCGCACCGCCGAGGTGGCCGGCAACCAGGTCCGGTTCCGCACCGGGGCCGGGATCGTGGTGGA
CTCGGACCCGCAGCGCGAGTTGGACGAAACCCGCGCCAAGGCGCGGGGCGTGTTGCGCGCGATCGAGCAAACATGA

Upstream 100 bases:

>100_bases
CTTCCGATGTTGAATTCGTTGATCAACCGTTGATCCACTCATCGCGCACGCTGCGTCTATCGCAGCGGCGCGCGTCTGCA
CCTCACGCCACGCCTGACCG

Downstream 100 bases:

>100_bases
GCGCTTCAACGGGACATCACCGGCACGCGGTATCCTGCGCGGCGATGGGGCAATGACGAGGTGGGTGTGGCGGTGACTGG
CAAACGCGGATGTCTGGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTLTRSLHADIDLLALHRLSPQRYPALLESTASGTAHGRWDVLLLAEGACLRLDPDGCTRNGEGQLLEASFLGALDAAWQ
AERVPHDAASPWPFRGGWAVLLDYELAAQVEPILQLPKRTDGLPTALALRAPAAVLRDRVQGRCVALAEPGRADLLQQIV
DDVAACSALPPLPDWMGPRAVEEDAPERFTAAVERVLDYLRAGDVFQANISRAWHAAFVDAVDPAALHARLRAANPAPFA
GLFVAAGRAVASSSPERLVSVQGEAVQTRPIAGTRARFVGDDDAARIRELVGHPKERAEHVMLIDLERNDLGRICAPGTV
EVDELMCVESYAHVHHIVSNVRGRLRAGVTPGEVIAAVFPGGTITGCPKVRCMQIIAELEQTARGAYTGAFGWLNRDGDM
DLNILIRTAEVAGNQVRFRTGAGIVVDSDPQRELDETRAKARGVLRAIEQT

Sequences:

>Translated_451_residues
MTLTRSLHADIDLLALHRLSPQRYPALLESTASGTAHGRWDVLLLAEGACLRLDPDGCTRNGEGQLLEASFLGALDAAWQ
AERVPHDAASPWPFRGGWAVLLDYELAAQVEPILQLPKRTDGLPTALALRAPAAVLRDRVQGRCVALAEPGRADLLQQIV
DDVAACSALPPLPDWMGPRAVEEDAPERFTAAVERVLDYLRAGDVFQANISRAWHAAFVDAVDPAALHARLRAANPAPFA
GLFVAAGRAVASSSPERLVSVQGEAVQTRPIAGTRARFVGDDDAARIRELVGHPKERAEHVMLIDLERNDLGRICAPGTV
EVDELMCVESYAHVHHIVSNVRGRLRAGVTPGEVIAAVFPGGTITGCPKVRCMQIIAELEQTARGAYTGAFGWLNRDGDM
DLNILIRTAEVAGNQVRFRTGAGIVVDSDPQRELDETRAKARGVLRAIEQT
>Mature_450_residues
TLTRSLHADIDLLALHRLSPQRYPALLESTASGTAHGRWDVLLLAEGACLRLDPDGCTRNGEGQLLEASFLGALDAAWQA
ERVPHDAASPWPFRGGWAVLLDYELAAQVEPILQLPKRTDGLPTALALRAPAAVLRDRVQGRCVALAEPGRADLLQQIVD
DVAACSALPPLPDWMGPRAVEEDAPERFTAAVERVLDYLRAGDVFQANISRAWHAAFVDAVDPAALHARLRAANPAPFAG
LFVAAGRAVASSSPERLVSVQGEAVQTRPIAGTRARFVGDDDAARIRELVGHPKERAEHVMLIDLERNDLGRICAPGTVE
VDELMCVESYAHVHHIVSNVRGRLRAGVTPGEVIAAVFPGGTITGCPKVRCMQIIAELEQTARGAYTGAFGWLNRDGDMD
LNILIRTAEVAGNQVRFRTGAGIVVDSDPQRELDETRAKARGVLRAIEQT

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=367, Percent_Identity=34.3324250681199, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1787518, Length=421, Percent_Identity=33.4916864608076, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI87082077, Length=294, Percent_Identity=25.5102040816327, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786809, Length=231, Percent_Identity=28.1385281385281, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=435, Percent_Identity=30.3448275862069, Blast_Score=170, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6324361, Length=396, Percent_Identity=24.7474747474747, Blast_Score=110, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR010118 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 48624; Mature: 48493

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTRSLHADIDLLALHRLSPQRYPALLESTASGTAHGRWDVLLLAEGACLRLDPDGCTR
CCCCCCHHCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEECCCCCCC
NGEGQLLEASFLGALDAAWQAERVPHDAASPWPFRGGWAVLLDYELAAQVEPILQLPKRT
CCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCC
DGLPTALALRAPAAVLRDRVQGRCVALAEPGRADLLQQIVDDVAACSALPPLPDWMGPRA
CCCCHHHHHHCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VEEDAPERFTAAVERVLDYLRAGDVFQANISRAWHAAFVDAVDPAALHARLRAANPAPFA
CCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHH
GLFVAAGRAVASSSPERLVSVQGEAVQTRPIAGTRARFVGDDDAARIRELVGHPKERAEH
HHHHHHCHHHHCCCCHHEEEECCCEEEECCCCCCCEEECCCCHHHHHHHHHCCCHHHCCE
VMLIDLERNDLGRICAPGTVEVDELMCVESYAHVHHIVSNVRGRLRAGVTPGEVIAAVFP
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEC
GGTITGCPKVRCMQIIAELEQTARGAYTGAFGWLNRDGDMDLNILIRTAEVAGNQVRFRT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEHHCCCEEEEEE
GAGIVVDSDPQRELDETRAKARGVLRAIEQT
CCEEEECCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLTRSLHADIDLLALHRLSPQRYPALLESTASGTAHGRWDVLLLAEGACLRLDPDGCTR
CCCCCHHCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEECCCCCCC
NGEGQLLEASFLGALDAAWQAERVPHDAASPWPFRGGWAVLLDYELAAQVEPILQLPKRT
CCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCC
DGLPTALALRAPAAVLRDRVQGRCVALAEPGRADLLQQIVDDVAACSALPPLPDWMGPRA
CCCCHHHHHHCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VEEDAPERFTAAVERVLDYLRAGDVFQANISRAWHAAFVDAVDPAALHARLRAANPAPFA
CCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHH
GLFVAAGRAVASSSPERLVSVQGEAVQTRPIAGTRARFVGDDDAARIRELVGHPKERAEH
HHHHHHCHHHHCCCCHHEEEECCCEEEECCCCCCCEEECCCCHHHHHHHHHCCCHHHCCE
VMLIDLERNDLGRICAPGTVEVDELMCVESYAHVHHIVSNVRGRLRAGVTPGEVIAAVFP
EEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEC
GGTITGCPKVRCMQIIAELEQTARGAYTGAFGWLNRDGDMDLNILIRTAEVAGNQVRFRT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEHHCCCEEEEEE
GAGIVVDSDPQRELDETRAKARGVLRAIEQT
CCEEEECCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]