Click here to switch to the map view.

The map label for this gene is dadA [H]

Identifier: 84622287

GI number: 84622287

Start: 683404

End: 684693

Strand: Direct

Name: dadA [H]

Synonym: XOO_0630

Alternate gene names: 84622287

Gene position: 683404-684693 (Clockwise)

Preceding gene: 84622285

Following gene: 84622288

Centisome position: 13.83

GC content: 67.98

Gene sequence:

>1290_bases
ATGCGTGTGCTCATTCTCGGCAGCGGCGTCATTGGCGTGACCAGTGCGTGGTACCTGGCGCAGGCCGGTTGCGAAGTGAC
CGTGGTTGACCGCCAGCCGGCCGCTGCGCTGGAGACCAGCTACGCCAACGCCGGCCAGCTGTCGTTCGGCTACACCTCTC
CCTGGGCCGCGCCCGGCGTGCCCGGCAAGGCGGTGAAGTGGCTGTTCGAACAGCATGCGCCGCTGTCGATCCGCCCCACC
CGCGACCTACGCCAGCTGGCGTGGCTGAGCCAGATGCTGCGCAACTGCACCGCCGAGCGGTATGCGGTGAACAAGGCGCG
CATGGTGCGCATGTCCGACTACAGTCGCGACTGCCTCAATGCACTGCGTGCCGAGACTGGGATCGAATTCGAAGGCCGCC
AGCTCGGCACCACCCAGTTGTTCCGCACCCAGCAGCAGCTTGACGCGGCTGCGCAGGACATCGAAGTGTTGGCCCAGTAC
GGCGTGCCGTACGAGCTGCTGAGCCCGGCGCAGATTGCGCAATTCGAGCCCGGACTGGCCGGCGGTGGCGCGCAGATGGC
CGGCGCACTGCGCCTGCCCGAAGACCAGACCGGCGACTGCCGCCTGTTCACCCAGCGCCTGGCCGAACTGGCTGCGCAGG
CAGGTGTCACCTTTCGCTACGGTTACCAGATCGAGTGGCTGGAACACGCTGGCGGCCAGGTCACCGGCGTGCAAATCGAT
GGCCGCATCGAAACCGCCGACCGCTACGTGCTGGCGCTGGGTAGCTATTCGGCCGACCTGTTGCTCTCGCTCGGCCTGCA
TCTGCCGGTGTACCCGCTCAAGGGCTACTCGCTCACCATCCCGATCGTCGATGCGCAGCGCGCGCCGACCTCCACCGTGC
TCGACGAAAGCTACAAGATCGCGCTCACCCGCTTCGACGACCGCATCCGCGTCGGCGGTATGGCCGAGGTGGCCGGCTTC
GACATGTCGCTGAATCCGCGTCGCCGCGCCACCCTGGAAATGGTGGTCAACGACCTGTTCCCCGGCGGTGGCGATCTGGC
CCAGGCCGAATTCTGGACCGGCCTGCGCCCGGCCACCCCGGATGGCACGCCGGTGGTCGGCGCCACGCCGTATGCCAACC
TGTTCCTCAACACCGGCCACGGCACGCTGGGCTGGACCATGGCCTGCGGCTCCGGACGCTACCTGGCCGATCTCATGCAG
GGCCGCACGCCGGAGATCGATACCGACGGTCTGGATATTTTCCGGTACCTGTCGCCACGCAGTGCGCGCCCGCAGCGGGA
GGCCGCCTAG

Upstream 100 bases:

>100_bases
GCCGATTCCAGAAATGGCACTGCCTGGCTCGCAATATACTGCGTCTAACTAGCCCCCTCGGCGCGTGGTTGTGGGGGAAT
GCCCTTTTGAGGAGAACGAC

Downstream 100 bases:

>100_bases
TGCGTCCTGCGCAAGCGTCGATCGATCTGGAGGCGTTGCGCCACAACTACCGCCTGGCCAAGCGCCTGGGTGGCAGCAAG
GCGCTGGCGGTGGTCAAGGC

Product: D-amino acid dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGVPGKAVKWLFEQHAPLSIRPT
RDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLNALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQY
GVPYELLSPAQIAQFEPGLAGGGAQMAGALRLPEDQTGDCRLFTQRLAELAAQAGVTFRYGYQIEWLEHAGGQVTGVQID
GRIETADRYVLALGSYSADLLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKIALTRFDDRIRVGGMAEVAGF
DMSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATPDGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQ
GRTPEIDTDGLDIFRYLSPRSARPQREAA

Sequences:

>Translated_429_residues
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGVPGKAVKWLFEQHAPLSIRPT
RDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLNALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQY
GVPYELLSPAQIAQFEPGLAGGGAQMAGALRLPEDQTGDCRLFTQRLAELAAQAGVTFRYGYQIEWLEHAGGQVTGVQID
GRIETADRYVLALGSYSADLLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKIALTRFDDRIRVGGMAEVAGF
DMSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATPDGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQ
GRTPEIDTDGLDIFRYLSPRSARPQREAA
>Mature_429_residues
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGVPGKAVKWLFEQHAPLSIRPT
RDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLNALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQY
GVPYELLSPAQIAQFEPGLAGGGAQMAGALRLPEDQTGDCRLFTQRLAELAAQAGVTFRYGYQIEWLEHAGGQVTGVQID
GRIETADRYVLALGSYSADLLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKIALTRFDDRIRVGGMAEVAGF
DMSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATPDGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQ
GRTPEIDTDGLDIFRYLSPRSARPQREAA

Specific function: Oxidative deamination of D-amino acids [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI194306651, Length=331, Percent_Identity=26.2839879154079, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787438, Length=416, Percent_Identity=61.5384615384615, Blast_Score=525, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023080
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.99.1 [H]

Molecular weight: Translated: 46674; Mature: 46674

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS01258 BH2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGV
CEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCCCEECCCCCCCCCCCC
PGKAVKWLFEQHAPLSIRPTRDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLN
CHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHCCCHHEEEEECCCCHHHHH
ALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQYGVPYELLSPAQIAQFEPGLA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCC
GGGAQMAGALRLPEDQTGDCRLFTQRLAELAAQAGVTFRYGYQIEWLEHAGGQVTGVQID
CCCHHHCCEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEECCEEEEHCCCCCEEEEEEEC
GRIETADRYVLALGSYSADLLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKI
CEEECCCEEEEEECCCCHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCHHHHCCCEEE
ALTRFDDRIRVGGMAEVAGFDMSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATP
EEEEECCCEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCC
DGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQGRTPEIDTDGLDIFRYLSPR
CCCEEECCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCC
SARPQREAA
CCCCCCCCC
>Mature Secondary Structure
MRVLILGSGVIGVTSAWYLAQAGCEVTVVDRQPAAALETSYANAGQLSFGYTSPWAAPGV
CEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCCCCEECCCCCCCCCCCC
PGKAVKWLFEQHAPLSIRPTRDLRQLAWLSQMLRNCTAERYAVNKARMVRMSDYSRDCLN
CHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCHHHHCCCHHEEEEECCCCHHHHH
ALRAETGIEFEGRQLGTTQLFRTQQQLDAAAQDIEVLAQYGVPYELLSPAQIAQFEPGLA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCC
GGGAQMAGALRLPEDQTGDCRLFTQRLAELAAQAGVTFRYGYQIEWLEHAGGQVTGVQID
CCCHHHCCEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEECCEEEEHCCCCCEEEEEEEC
GRIETADRYVLALGSYSADLLLSLGLHLPVYPLKGYSLTIPIVDAQRAPTSTVLDESYKI
CEEECCCEEEEEECCCCHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCHHHHCCCEEE
ALTRFDDRIRVGGMAEVAGFDMSLNPRRRATLEMVVNDLFPGGGDLAQAEFWTGLRPATP
EEEEECCCEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCC
DGTPVVGATPYANLFLNTGHGTLGWTMACGSGRYLADLMQGRTPEIDTDGLDIFRYLSPR
CCCEEECCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCC
SARPQREAA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]