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The map label for this gene is alr [H]

Identifier: 84622288

GI number: 84622288

Start: 684693

End: 685793

Strand: Direct

Name: alr [H]

Synonym: XOO_0631

Alternate gene names: 84622288

Gene position: 684693-685793 (Clockwise)

Preceding gene: 84622287

Following gene: 84622290

Centisome position: 13.86

GC content: 68.39

Gene sequence:

>1101_bases
GTGCGTCCTGCGCAAGCGTCGATCGATCTGGAGGCGTTGCGCCACAACTACCGCCTGGCCAAGCGCCTGGGTGGCAGCAA
GGCGCTGGCGGTGGTCAAGGCCGATGCTTACGGGCATGGCGCAGTGCCTTGCGCGCAGGCGCTGGAACCGGAGGCCGATG
GCTTCGCGGTGGCCTGCATCGAAGAGGCGCTGGAACTGCGCCAGGCCGGCATCCGCGCGCCAATCCTGTTGCTGGAAGGG
TTCTTCGAGCACGACGAGCTGCGCCTGATCGCCGAGCACGACCTGTGGACGGTGGCGGCTACGCCGCAACAGGTGCGCGC
GCTGGCCGCGTTCCAGAGCCCACGACCGTTGCGGGTGTGGTTGAAGATGGACAGCGGCATGCATCGGCTGGGCCTGTCGC
CGGAAGACTTCCGCGCCGCATGGCTGCGCCTGCGCGGGCTGCCGCAGATCGCCTCGCTGGTGCTGATGACCCACCTGGCG
CGCGCCGACGAATTGGACTGCAGCCGCACAGACGAACAGGCGGTGGCCTTTGCGCTGACCGCCGGCGGCATGCGCGCGGA
AACCAGTCTGCGCAATTCGCCCGGCCTGCTCGGCTGGCCGGCGCTGCGCAACGACTGGTCGCGCCCGGGGCTGATGTTGT
ACGGCGCCAACCCGTTCCCGCAGGACACCGAGAACACTGCGCAATTGCGCCCGGTGATGACGCTGCGCTCGCGCATCATT
TTGGTCCGCGACCTGCCGGTCGGCGAACCGGTGGGCTACGGCGCCCGTTTTGTCGCCGAACGACCGACCCGCGTCGGCGT
GGTGGCGATGGGCTATGCCGACGGCTACCCGCAGTTCGCGCCGAACGGCACCCCGGTGCTGGTGGATGGCCAGGTCTGCC
CATTGATCGGTCGCGTCTCGATGGACATGCTCACCGTGGACCTCACCGACCATCCGCAGGCCGACATTGGTGCCACCGTG
CAGCTGTGGGGCCAGGCACCACGCGTTGGCCCACTGGCCACGCAATGCAATGTCAGCGCGTATCAGCTGTTGTGTGGACT
CAAGCGCGTGCCGCGGACGTATGTGGCTAGTGCGGCAGTGGGCGAGGTTGCAGCGCGGTAA

Upstream 100 bases:

>100_bases
ATCTCATGCAGGGCCGCACGCCGGAGATCGATACCGACGGTCTGGATATTTTCCGGTACCTGTCGCCACGCAGTGCGCGC
CCGCAGCGGGAGGCCGCCTA

Downstream 100 bases:

>100_bases
CGTGGATTCCTTCTCCCATCGGGACGTTGTCCTTCGTCATGGGGGAGAAGGTGCCCCGACGGGGCGGATGAGGGGACGGG
CGACGTCACATGCAATTGGA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MRPAQASIDLEALRHNYRLAKRLGGSKALAVVKADAYGHGAVPCAQALEPEADGFAVACIEEALELRQAGIRAPILLLEG
FFEHDELRLIAEHDLWTVAATPQQVRALAAFQSPRPLRVWLKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLA
RADELDCSRTDEQAVAFALTAGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQDTENTAQLRPVMTLRSRII
LVRDLPVGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQVCPLIGRVSMDMLTVDLTDHPQADIGATV
QLWGQAPRVGPLATQCNVSAYQLLCGLKRVPRTYVASAAVGEVAAR

Sequences:

>Translated_366_residues
MRPAQASIDLEALRHNYRLAKRLGGSKALAVVKADAYGHGAVPCAQALEPEADGFAVACIEEALELRQAGIRAPILLLEG
FFEHDELRLIAEHDLWTVAATPQQVRALAAFQSPRPLRVWLKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLA
RADELDCSRTDEQAVAFALTAGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQDTENTAQLRPVMTLRSRII
LVRDLPVGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQVCPLIGRVSMDMLTVDLTDHPQADIGATV
QLWGQAPRVGPLATQCNVSAYQLLCGLKRVPRTYVASAAVGEVAAR
>Mature_366_residues
MRPAQASIDLEALRHNYRLAKRLGGSKALAVVKADAYGHGAVPCAQALEPEADGFAVACIEEALELRQAGIRAPILLLEG
FFEHDELRLIAEHDLWTVAATPQQVRALAAFQSPRPLRVWLKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLA
RADELDCSRTDEQAVAFALTAGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQDTENTAQLRPVMTLRSRII
LVRDLPVGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQVCPLIGRVSMDMLTVDLTDHPQADIGATV
QLWGQAPRVGPLATQCNVSAYQLLCGLKRVPRTYVASAAVGEVAAR

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=360, Percent_Identity=45.5555555555556, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI1787439, Length=358, Percent_Identity=44.1340782122905, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39693; Mature: 39693

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAQASIDLEALRHNYRLAKRLGGSKALAVVKADAYGHGAVPCAQALEPEADGFAVACI
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHCCCCCCCEEHHHH
EEALELRQAGIRAPILLLEGFFEHDELRLIAEHDLWTVAATPQQVRALAAFQSPRPLRVW
HHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCEEEEECCHHHHHHHHHHCCCCCEEEE
LKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLARADELDCSRTDEQAVAFALT
EEECCCCHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
AGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQDTENTAQLRPVMTLRSRII
CCCCCCCCCCCCCCCCEECHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCEEE
LVRDLPVGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQVCPLIGRVS
EEEECCCCCCCCCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCCHHHHCE
MDMLTVDLTDHPQADIGATVQLWGQAPRVGPLATQCNVSAYQLLCGLKRVPRTYVASAAV
EEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
GEVAAR
HHHHCC
>Mature Secondary Structure
MRPAQASIDLEALRHNYRLAKRLGGSKALAVVKADAYGHGAVPCAQALEPEADGFAVACI
CCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHCCCCCCCEEHHHH
EEALELRQAGIRAPILLLEGFFEHDELRLIAEHDLWTVAATPQQVRALAAFQSPRPLRVW
HHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCEEEEECCHHHHHHHHHHCCCCCEEEE
LKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLARADELDCSRTDEQAVAFALT
EEECCCCHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
AGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQDTENTAQLRPVMTLRSRII
CCCCCCCCCCCCCCCCEECHHHHCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCEEE
LVRDLPVGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQVCPLIGRVS
EEEECCCCCCCCCCCEEEECCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCCHHHHCE
MDMLTVDLTDHPQADIGATVQLWGQAPRVGPLATQCNVSAYQLLCGLKRVPRTYVASAAV
EEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
GEVAAR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]