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The map label for this gene is zraS [C]

Identifier: 84622277

GI number: 84622277

Start: 674808

End: 676505

Strand: Direct

Name: zraS [C]

Synonym: XOO_0619

Alternate gene names: 84622277

Gene position: 674808-676505 (Clockwise)

Preceding gene: 84622274

Following gene: 84622285

Centisome position: 13.66

GC content: 65.67

Gene sequence:

>1698_bases
ATGGCGCGTGTCAGCGGCCGCCGCGGTGGTGGTGCGATGCAGGCGGTGCTACCGGCGGGGCGGGCAGCGGCGAGGCGGGC
GCGGTGCTGGCCCGTTACATGGTCAGGCAGAAGGCTCATCGGTGTCCCCAGAACGTGGTGGGCGGAGCGACTGGCGCCGA
CCGAACTCCAAGGCATCCCCCTGTCGATGCGGAGTTGTGTCGGCGAACACGAAGTGCGCCAAAAACTTGTCACGCAGATC
CCGGGCTGTCACCAAACGACGATTGCATCCACTCACCACCGATGTGAGCATCCAGCGTTGTCTAGGTCGCCTGCTGCCAG
TTCTGTGAAATTCATCTCAGTTTTGCCCTGGTTGCAGCCACCGACGTCCGCCAGTGCCAGCGACCATCGGCATGCGGCGT
TCCTGCAAGTGTTGCTGGCGGCGATCGTGCTCTATACCGCCGGCGACATCGGCCTGTTTCTCTACGTGGCTGGCGCTGCG
CGCTTGCTGAGTCACACGGACCTGTTGTTTGCCCTGGTGGGTAGCGTGCTCACTGCGGTAGGTGCGGCGCTGGGCGTGTG
GCGCGTGCGGCGCGGCGACAATGCGGGGGCGGTGCGGACTTACGTGGCCGCGACGTTGATCGGCGTGGTGGTTACCTATG
TGCGGGTGGACATTTACGACCTGCTGACCAACCCCATGCCCTTGCTGGCGCTGGTACTCGCCGGCATGGTGCTGGGGAGT
CGCGCGCTCTGGCGCGTGTTCCTGTTGCTGGCGGCTGCTGCGTTGCTGGGCGTGCTCGCACAGGTGATCTGGCCGGTGCC
CTGGCGCTCGGTGCGCGGCAACATCGGCTTGGGCCTGGTGACCGTCGGTGCCTATCTGCTGATCACTCTCAGCCTGGATC
GCACCATCGCCGCATTGCGTGACAGCCTGCTCGAATCAGAACACCGCCGGCGCGAACTGGAACAGCTCAATCGCCGTCTG
CTGCAGGAAATGGCCGAGCGCGAACGCGTGCAGGAGCAACTGATCCACATCCAGAAAATGGAAGCGCTCGGGCGTCTGGC
AGCTGGCGTCGCGCACGATTTCGATAATCTGATCAACGTGATCATCGGCTACGCGCAACGGCGCGATGCGCTGGAGGGCT
ACGGCGAAGCGCCGCTGCTCAAAACGCTGGAAAACATCGAGACCGCCTCGCGGCGCGCGTTGACAGTCAGCCGGCGCATC
CTCAACTTCGGCCGCGCCGAGCCCGACCTGCCGACCCTGTTCGATGCCCGCGCAGCACTGCGCGATGCCGAACCCACCTT
GCGTCAGCTATTCGGGCACGACATCCGGCTGGAGTGCATCGCCGCCGGGCCGCCGCTGTGGGTCCTGATGGATCGCGATG
ATCTCGAACTGGTGCTGCTCAACATCGCCGCCAACGCGCGCGACGCGATGGAGGAGCAGGGCGTGTTCCGTATCGAAGGC
GAGTTGCGCGAGGCCACGGTGTGCTTGCGTTTCTGCGATACCGGTCCGGGCATTGCACCGCATCTGCTGGCGCGAATTCT
CGAGCCGTTCTACACCACCAAGCCGGTCGGCAAGGGCACCGGGCTGGGCTTGTCGGTGGTGCAAAGCATCATCGCCGCGG
CCGGTGGCCAGGTGGCGGCGTGCAATGGTCCGCAAGGCGGGGCCTGTCTGTGCCTGCAATTGCCGCTGGCGGCGGCGCCT
CAGTCGGCCAGCAGGTAG

Upstream 100 bases:

>100_bases
GTCGGCGGTGCTGGCTTGGCTGGTCGGGCTTGTCGCTTCTGGCGCAGGTGTGGCGGTGTGTGCAGTTGCCAGACGACTGG
CCAGAAACAGGAGGGTGAGC

Downstream 100 bases:

>100_bases
CCCATGCCACGGGAGGACAACAGCGGCAGCGCCGGTGTCCGATCGCTGGAGATGCGTGCGGCCTTGCGCCGCAGACGATG
GATCAGCATTTCCAGCCGGT

Product: hypothetical protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MARVSGRRGGGAMQAVLPAGRAAARRARCWPVTWSGRRLIGVPRTWWAERLAPTELQGIPLSMRSCVGEHEVRQKLVTQI
PGCHQTTIASTHHRCEHPALSRSPAASSVKFISVLPWLQPPTSASASDHRHAAFLQVLLAAIVLYTAGDIGLFLYVAGAA
RLLSHTDLLFALVGSVLTAVGAALGVWRVRRGDNAGAVRTYVAATLIGVVVTYVRVDIYDLLTNPMPLLALVLAGMVLGS
RALWRVFLLLAAAALLGVLAQVIWPVPWRSVRGNIGLGLVTVGAYLLITLSLDRTIAALRDSLLESEHRRRELEQLNRRL
LQEMAERERVQEQLIHIQKMEALGRLAAGVAHDFDNLINVIIGYAQRRDALEGYGEAPLLKTLENIETASRRALTVSRRI
LNFGRAEPDLPTLFDARAALRDAEPTLRQLFGHDIRLECIAAGPPLWVLMDRDDLELVLLNIAANARDAMEEQGVFRIEG
ELREATVCLRFCDTGPGIAPHLLARILEPFYTTKPVGKGTGLGLSVVQSIIAAAGGQVAACNGPQGGACLCLQLPLAAAP
QSASR

Sequences:

>Translated_565_residues
MARVSGRRGGGAMQAVLPAGRAAARRARCWPVTWSGRRLIGVPRTWWAERLAPTELQGIPLSMRSCVGEHEVRQKLVTQI
PGCHQTTIASTHHRCEHPALSRSPAASSVKFISVLPWLQPPTSASASDHRHAAFLQVLLAAIVLYTAGDIGLFLYVAGAA
RLLSHTDLLFALVGSVLTAVGAALGVWRVRRGDNAGAVRTYVAATLIGVVVTYVRVDIYDLLTNPMPLLALVLAGMVLGS
RALWRVFLLLAAAALLGVLAQVIWPVPWRSVRGNIGLGLVTVGAYLLITLSLDRTIAALRDSLLESEHRRRELEQLNRRL
LQEMAERERVQEQLIHIQKMEALGRLAAGVAHDFDNLINVIIGYAQRRDALEGYGEAPLLKTLENIETASRRALTVSRRI
LNFGRAEPDLPTLFDARAALRDAEPTLRQLFGHDIRLECIAAGPPLWVLMDRDDLELVLLNIAANARDAMEEQGVFRIEG
ELREATVCLRFCDTGPGIAPHLLARILEPFYTTKPVGKGTGLGLSVVQSIIAAAGGQVAACNGPQGGACLCLQLPLAAAP
QSASR
>Mature_564_residues
ARVSGRRGGGAMQAVLPAGRAAARRARCWPVTWSGRRLIGVPRTWWAERLAPTELQGIPLSMRSCVGEHEVRQKLVTQIP
GCHQTTIASTHHRCEHPALSRSPAASSVKFISVLPWLQPPTSASASDHRHAAFLQVLLAAIVLYTAGDIGLFLYVAGAAR
LLSHTDLLFALVGSVLTAVGAALGVWRVRRGDNAGAVRTYVAATLIGVVVTYVRVDIYDLLTNPMPLLALVLAGMVLGSR
ALWRVFLLLAAAALLGVLAQVIWPVPWRSVRGNIGLGLVTVGAYLLITLSLDRTIAALRDSLLESEHRRRELEQLNRRLL
QEMAERERVQEQLIHIQKMEALGRLAAGVAHDFDNLINVIIGYAQRRDALEGYGEAPLLKTLENIETASRRALTVSRRIL
NFGRAEPDLPTLFDARAALRDAEPTLRQLFGHDIRLECIAAGPPLWVLMDRDDLELVLLNIAANARDAMEEQGVFRIEGE
LREATVCLRFCDTGPGIAPHLLARILEPFYTTKPVGKGTGLGLSVVQSIIAAAGGQVAACNGPQGGACLCLQLPLAAAPQ
SASR

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=32.2175732217573, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=29.7959183673469, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788393, Length=113, Percent_Identity=32.7433628318584, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI87081816, Length=135, Percent_Identity=34.8148148148148, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61167; Mature: 61036

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVSGRRGGGAMQAVLPAGRAAARRARCWPVTWSGRRLIGVPRTWWAERLAPTELQGIP
CCCCCCCCCCCHHHHHHCCCHHHHHCCCCCCEECCCCEEECCCCHHHHHHCCCCCCCCCC
LSMRSCVGEHEVRQKLVTQIPGCHQTTIASTHHRCEHPALSRSPAASSVKFISVLPWLQP
HHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCC
PTSASASDHRHAAFLQVLLAAIVLYTAGDIGLFLYVAGAARLLSHTDLLFALVGSVLTAV
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAALGVWRVRRGDNAGAVRTYVAATLIGVVVTYVRVDIYDLLTNPMPLLALVLAGMVLGS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RALWRVFLLLAAAALLGVLAQVIWPVPWRSVRGNIGLGLVTVGAYLLITLSLDRTIAALR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DSLLESEHRRRELEQLNRRLLQEMAERERVQEQLIHIQKMEALGRLAAGVAHDFDNLINV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGYAQRRDALEGYGEAPLLKTLENIETASRRALTVSRRILNFGRAEPDLPTLFDARAAL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RDAEPTLRQLFGHDIRLECIAAGPPLWVLMDRDDLELVLLNIAANARDAMEEQGVFRIEG
HCCCHHHHHHCCCCCEEEEEECCCCEEEEECCCCCEEEEEEHHCCHHHHHHHCCCEEEEC
ELREATVCLRFCDTGPGIAPHLLARILEPFYTTKPVGKGTGLGLSVVQSIIAAAGGQVAA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
CNGPQGGACLCLQLPLAAAPQSASR
CCCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
ARVSGRRGGGAMQAVLPAGRAAARRARCWPVTWSGRRLIGVPRTWWAERLAPTELQGIP
CCCCCCCCCCHHHHHHCCCHHHHHCCCCCCEECCCCEEECCCCHHHHHHCCCCCCCCCC
LSMRSCVGEHEVRQKLVTQIPGCHQTTIASTHHRCEHPALSRSPAASSVKFISVLPWLQP
HHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCC
PTSASASDHRHAAFLQVLLAAIVLYTAGDIGLFLYVAGAARLLSHTDLLFALVGSVLTAV
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAALGVWRVRRGDNAGAVRTYVAATLIGVVVTYVRVDIYDLLTNPMPLLALVLAGMVLGS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RALWRVFLLLAAAALLGVLAQVIWPVPWRSVRGNIGLGLVTVGAYLLITLSLDRTIAALR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DSLLESEHRRRELEQLNRRLLQEMAERERVQEQLIHIQKMEALGRLAAGVAHDFDNLINV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGYAQRRDALEGYGEAPLLKTLENIETASRRALTVSRRILNFGRAEPDLPTLFDARAAL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RDAEPTLRQLFGHDIRLECIAAGPPLWVLMDRDDLELVLLNIAANARDAMEEQGVFRIEG
HCCCHHHHHHCCCCCEEEEEECCCCEEEEECCCCCEEEEEEHHCCHHHHHHHCCCEEEEC
ELREATVCLRFCDTGPGIAPHLLARILEPFYTTKPVGKGTGLGLSVVQSIIAAAGGQVAA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
CNGPQGGACLCLQLPLAAAPQSASR
CCCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA