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The map label for this gene is yfcG [H]

Identifier: 84622017

GI number: 84622017

Start: 390281

End: 390970

Strand: Direct

Name: yfcG [H]

Synonym: XOO_0360

Alternate gene names: 84622017

Gene position: 390281-390970 (Clockwise)

Preceding gene: 84622016

Following gene: 84622018

Centisome position: 7.9

GC content: 63.04

Gene sequence:

>690_bases
ATGATTGATCTGTACTACTGGCCCACGCCCAATGGCCACAAAGTCACCTTGTTCCTGGAAGAGGCCGGGCTGAAGTACAC
CGTCAAGCCGGTCAATATCGGCAAGGGCGAACAATTCGAGCCGGCGTTCCTGCAGATTTCGCCCAACAACAAGATGCCGG
CCATCGTCGACCATGCACCGGTCGATGGCGGCGGCGCGCAGAGCGTGTTCGAATCCGGCGCGATCCTGCTGTACTTGGCC
GAGAGGACTGGCCGCTTTCTGCCGCGCGATGCGCGCGGCCGCATCGCTGCGCTGGAGTGGTTGTTCTGGCAGATGGGCGG
GCTGGGCCCGATGAGCGGGCAGATGGGCCACTTCAACGTGTATGCACCGGAAAAGATTCCGTACGCGATCGAGCGCTACA
CCGCCGAGGTGCGCCGCCTGCATGGCGTGCTCGACAAGCGTCTGGCTGATCACGCCTTCTTGGCGGGCAACGATTACGGC
ATCGCCGACATGGCCAGCTATCCGTGGATCGAAGTGTATGGCGACCTCCAGCCGGACTATTCCGCCTTCCCGCATCTGAA
GCGCTGGCACGACGCCATCGCCGCCCGCCCCGCCACCCAGCGTGCCTACGCACTCAAGGACCAGGTCAATCCCAATGCCG
GCAAGCCGCTCAGCGATGAGGAGCGCAAACACCTGTTCGGTAAGCGCTGA

Upstream 100 bases:

>100_bases
AGGTGGACCAGATGCATTGCCGGGTTCGATGCCTGCACGCCGAAGACCGTCACCTTGTTGTGTCTTGCCGTTACGACCCC
ACCTGTGACTGGAGCGCACG

Downstream 100 bases:

>100_bases
AGGCCCAGTCGTAACAGCAGAGCAGGCATAGCCGCGCAACAGGATCGCTGAAGCCCCTTCGACATCGGGAGAGCAGCGCA
AGAAGTTCCTCCCCCGCCGG

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MIDLYYWPTPNGHKVTLFLEEAGLKYTVKPVNIGKGEQFEPAFLQISPNNKMPAIVDHAPVDGGGAQSVFESGAILLYLA
ERTGRFLPRDARGRIAALEWLFWQMGGLGPMSGQMGHFNVYAPEKIPYAIERYTAEVRRLHGVLDKRLADHAFLAGNDYG
IADMASYPWIEVYGDLQPDYSAFPHLKRWHDAIAARPATQRAYALKDQVNPNAGKPLSDEERKHLFGKR

Sequences:

>Translated_229_residues
MIDLYYWPTPNGHKVTLFLEEAGLKYTVKPVNIGKGEQFEPAFLQISPNNKMPAIVDHAPVDGGGAQSVFESGAILLYLA
ERTGRFLPRDARGRIAALEWLFWQMGGLGPMSGQMGHFNVYAPEKIPYAIERYTAEVRRLHGVLDKRLADHAFLAGNDYG
IADMASYPWIEVYGDLQPDYSAFPHLKRWHDAIAARPATQRAYALKDQVNPNAGKPLSDEERKHLFGKR
>Mature_229_residues
MIDLYYWPTPNGHKVTLFLEEAGLKYTVKPVNIGKGEQFEPAFLQISPNNKMPAIVDHAPVDGGGAQSVFESGAILLYLA
ERTGRFLPRDARGRIAALEWLFWQMGGLGPMSGQMGHFNVYAPEKIPYAIERYTAEVRRLHGVLDKRLADHAFLAGNDYG
IADMASYPWIEVYGDLQPDYSAFPHLKRWHDAIAARPATQRAYALKDQVNPNAGKPLSDEERKHLFGKR

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=209, Percent_Identity=59.3301435406699, Blast_Score=255, Evalue=2e-69,
Organism=Escherichia coli, GI87082195, Length=226, Percent_Identity=42.9203539823009, Blast_Score=174, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6324100, Length=232, Percent_Identity=32.3275862068966, Blast_Score=111, Evalue=7e-26,
Organism=Drosophila melanogaster, GI17864592, Length=194, Percent_Identity=27.319587628866, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571670, Length=174, Percent_Identity=26.4367816091954, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864594, Length=203, Percent_Identity=26.6009852216749, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864598, Length=200, Percent_Identity=26.5, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17933730, Length=193, Percent_Identity=26.4248704663212, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24646249, Length=195, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 25726; Mature: 25726

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYYWPTPNGHKVTLFLEEAGLKYTVKPVNIGKGEQFEPAFLQISPNNKMPAIVDHAP
CCEEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCEEEECCC
VDGGGAQSVFESGAILLYLAERTGRFLPRDARGRIAALEWLFWQMGGLGPMSGQMGHFNV
CCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEE
YAPEKIPYAIERYTAEVRRLHGVLDKRLADHAFLAGNDYGIADMASYPWIEVYGDLQPDY
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHCCCCEEEEECCCCCCH
SAFPHLKRWHDAIAARPATQRAYALKDQVNPNAGKPLSDEERKHLFGKR
HHCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCC
>Mature Secondary Structure
MIDLYYWPTPNGHKVTLFLEEAGLKYTVKPVNIGKGEQFEPAFLQISPNNKMPAIVDHAP
CCEEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCEEEECCC
VDGGGAQSVFESGAILLYLAERTGRFLPRDARGRIAALEWLFWQMGGLGPMSGQMGHFNV
CCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEE
YAPEKIPYAIERYTAEVRRLHGVLDKRLADHAFLAGNDYGIADMASYPWIEVYGDLQPDY
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHCCCCEEEEECCCCCCH
SAFPHLKRWHDAIAARPATQRAYALKDQVNPNAGKPLSDEERKHLFGKR
HHCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]