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The map label for this gene is dut [H]

Identifier: 84489413

GI number: 84489413

Start: 699829

End: 700287

Strand: Direct

Name: dut [H]

Synonym: Msp_0604

Alternate gene names: 84489413

Gene position: 699829-700287 (Clockwise)

Preceding gene: 84489410

Following gene: 84489414

Centisome position: 39.6

GC content: 30.5

Gene sequence:

>459_bases
ATGTTAGGCGAAAAAGAATTATTAAAGTTATTTCCAGAGTATTCAGACACAATACAACCTTCAGGTATTGATTTAAGAAT
GGATAAAATATATAGACAAGTCGGTTCTGGTTCACTAATTGATAATGAGAAAAATCTACCAGAAATTGAAGAACTGGAAT
CTGTAGATGATATTTATACTTTAGAACCAAAAACAGCATATAGTGTTACTATAGAAGGTAAAATTGAAATACCTACAGGT
TATACAATGTTATATCTTCCAAGATCAACACTTCTTCGTTCTTTTATCAGTGTACATACTGCTGTTGGAGATCCTGGATT
TTATGGAACTTTACAATTTATGATTGTTAATAATGGTCAGTATCCCTACAAGATAAAAAAAGGTGAAAGAATAGCTCAAG
CAGTTGTATTTCCAGTAGAAGGATCTGGTAAATATAATGGATCTTATCAGGAAAAATAA

Upstream 100 bases:

>100_bases
TTACATTTTTTTGAATGATTATTAACATTAAATAATTATAGTATGAAGTAATAAATATTATATTTAAATAGGAGAATAAT
TTATAGGAGAATAATAAATT

Downstream 100 bases:

>100_bases
GTTAGTGGAGTGTTTTTATGAAGAAAGATAAAAATATTGCACAGTTTTTAATTGATAAATTAGAATCTAATGGTGTTGAA
TATGTATTTGGATATCCTGG

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dUTPase; dUTP pyrophosphatase [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MLGEKELLKLFPEYSDTIQPSGIDLRMDKIYRQVGSGSLIDNEKNLPEIEELESVDDIYTLEPKTAYSVTIEGKIEIPTG
YTMLYLPRSTLLRSFISVHTAVGDPGFYGTLQFMIVNNGQYPYKIKKGERIAQAVVFPVEGSGKYNGSYQEK

Sequences:

>Translated_152_residues
MLGEKELLKLFPEYSDTIQPSGIDLRMDKIYRQVGSGSLIDNEKNLPEIEELESVDDIYTLEPKTAYSVTIEGKIEIPTG
YTMLYLPRSTLLRSFISVHTAVGDPGFYGTLQFMIVNNGQYPYKIKKGERIAQAVVFPVEGSGKYNGSYQEK
>Mature_152_residues
MLGEKELLKLFPEYSDTIQPSGIDLRMDKIYRQVGSGSLIDNEKNLPEIEELESVDDIYTLEPKTAYSVTIEGKIEIPTG
YTMLYLPRSTLLRSFISVHTAVGDPGFYGTLQFMIVNNGQYPYKIKKGERIAQAVVFPVEGSGKYNGSYQEK

Specific function: This enzyme is involved in nucleotide metabolism:it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA [H]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family. Archaeal dUTPase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008180 [H]

Pfam domain/function: PF00692 dUTPase [H]

EC number: =3.6.1.23 [H]

Molecular weight: Translated: 17127; Mature: 17127

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGEKELLKLFPEYSDTIQPSGIDLRMDKIYRQVGSGSLIDNEKNLPEIEELESVDDIYT
CCCHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHCCCCEECCCCCCCHHHHHHCCCCEEE
LEPKTAYSVTIEGKIEIPTGYTMLYLPRSTLLRSFISVHTAVGDPGFYGTLQFMIVNNGQ
ECCCCEEEEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCC
YPYKIKKGERIAQAVVFPVEGSGKYNGSYQEK
CCEEECCCCEEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MLGEKELLKLFPEYSDTIQPSGIDLRMDKIYRQVGSGSLIDNEKNLPEIEELESVDDIYT
CCCHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHCCCCEECCCCCCCHHHHHHCCCCEEE
LEPKTAYSVTIEGKIEIPTGYTMLYLPRSTLLRSFISVHTAVGDPGFYGTLQFMIVNNGQ
ECCCCEEEEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCC
YPYKIKKGERIAQAVVFPVEGSGKYNGSYQEK
CCEEECCCCEEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]