Click here to switch to the map view.

The map label for this gene is sucD

Identifier: 84489392

GI number: 84489392

Start: 675113

End: 675979

Strand: Direct

Name: sucD

Synonym: Msp_0583

Alternate gene names: 84489392

Gene position: 675113-675979 (Clockwise)

Preceding gene: 84489391

Following gene: 84489393

Centisome position: 38.2

GC content: 33.22

Gene sequence:

>867_bases
GTGATATTACTAGATGAGAATACAAAAGCAGTTGTTCAAGGAATCACTGGAAAACAGGGACGTTTTCATACAAAAGAAAT
GGTGGAATACAATACTAATATTGTAGCAGGAACAAGTCCAGGAAAAGCAGGACAAACAGTTGATGGTGTACCAGTATATA
ATTCCATTGAGGAAATTAAACAAAAACATCCTGAGGTCAATGCTAGTATTATATTTATACCAGCACCATTTGTAAAAGAT
GCAGCATTTGAAGCAATAAGTCAATTAGATTTGGTTATTATTATAACAGAACATTTACCAATTCATGATTCAATGGAAAT
TGTTGAATATGCAAAACAACATAATACTACTTTAATTGGTCCAAATACTCCTGGAATTATAACACCAGGTGTTGGAAAAC
TTGGAATAATGCCAACACATATATTTAAAAAAGGAAAAGTAGGATTAGTATCTAGAAGTGGAACTTTAACATATGAAGTA
GCAAGTCAAATAAGTGCTGCAGGTTATGGTTTAAGTACTGCTGTGGGTGTAGGGGGAGACCCTGTAACTGGTGAAAGTTT
TACAAATATCTTAGAAAAATTTGAAAATGATCCAGAAACTGAACAAATTGTTATGTTAGGTGAAATTGGAGGAATAGCTG
AAGTAAAAGCTGCAAAATATGCTCAAGAAAACTTAACAAAACCAATAATCTCATTTATTGCAGGAGTATCTGCACCTCTT
GGAAAAAGAATGGGGCATGCAGGAGCTATTATTGAAGGAACTGATGGTACTGCTCAAAATAAAAAGGAACTACTTAAAAG
TTATGGAGTTCATGTGGCTGATATACCTTCAGATATAGTAACAATACTTAATGAGATTACTGAATAA

Upstream 100 bases:

>100_bases
ATGAAATATGAGTTATATATTTTTTTAAAAAAATTTATTTTTGAAGAACATTAAATATAATATCAAATTAATAAAGAAAA
ATAAAATAAGGGGAATATTT

Downstream 100 bases:

>100_bases
TTTCAAATTCAATAACACTACTTCTTGTGGTGTTTATTACATTTTAATTCTTTTTTTATTCAATAGCTAAAAAATCATAA
CTTATTTTTAAAATAATTAT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MILLDENTKAVVQGITGKQGRFHTKEMVEYNTNIVAGTSPGKAGQTVDGVPVYNSIEEIKQKHPEVNASIIFIPAPFVKD
AAFEAISQLDLVIIITEHLPIHDSMEIVEYAKQHNTTLIGPNTPGIITPGVGKLGIMPTHIFKKGKVGLVSRSGTLTYEV
ASQISAAGYGLSTAVGVGGDPVTGESFTNILEKFENDPETEQIVMLGEIGGIAEVKAAKYAQENLTKPIISFIAGVSAPL
GKRMGHAGAIIEGTDGTAQNKKELLKSYGVHVADIPSDIVTILNEITE

Sequences:

>Translated_288_residues
MILLDENTKAVVQGITGKQGRFHTKEMVEYNTNIVAGTSPGKAGQTVDGVPVYNSIEEIKQKHPEVNASIIFIPAPFVKD
AAFEAISQLDLVIIITEHLPIHDSMEIVEYAKQHNTTLIGPNTPGIITPGVGKLGIMPTHIFKKGKVGLVSRSGTLTYEV
ASQISAAGYGLSTAVGVGGDPVTGESFTNILEKFENDPETEQIVMLGEIGGIAEVKAAKYAQENLTKPIISFIAGVSAPL
GKRMGHAGAIIEGTDGTAQNKKELLKSYGVHVADIPSDIVTILNEITE
>Mature_288_residues
MILLDENTKAVVQGITGKQGRFHTKEMVEYNTNIVAGTSPGKAGQTVDGVPVYNSIEEIKQKHPEVNASIIFIPAPFVKD
AAFEAISQLDLVIIITEHLPIHDSMEIVEYAKQHNTTLIGPNTPGIITPGVGKLGIMPTHIFKKGKVGLVSRSGTLTYEV
ASQISAAGYGLSTAVGVGGDPVTGESFTNILEKFENDPETEQIVMLGEIGGIAEVKAAKYAQENLTKPIISFIAGVSAPL
GKRMGHAGAIIEGTDGTAQNKKELLKSYGVHVADIPSDIVTILNEITE

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=288, Percent_Identity=48.6111111111111, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI38569423, Length=253, Percent_Identity=32.0158102766798, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI38569421, Length=253, Percent_Identity=32.0158102766798, Blast_Score=123, Evalue=1e-28,
Organism=Escherichia coli, GI1786949, Length=288, Percent_Identity=51.0416666666667, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1786513, Length=225, Percent_Identity=24, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17553126, Length=284, Percent_Identity=47.1830985915493, Blast_Score=245, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17550194, Length=286, Percent_Identity=47.5524475524476, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17557344, Length=302, Percent_Identity=29.4701986754967, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17551266, Length=302, Percent_Identity=28.476821192053, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324716, Length=285, Percent_Identity=45.6140350877193, Blast_Score=225, Evalue=7e-60,
Organism=Drosophila melanogaster, GI21356559, Length=290, Percent_Identity=45.5172413793103, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI28574296, Length=283, Percent_Identity=46.643109540636, Blast_Score=223, Evalue=9e-59,
Organism=Drosophila melanogaster, GI281363477, Length=239, Percent_Identity=30.1255230125523, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI281363475, Length=239, Percent_Identity=30.1255230125523, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281363473, Length=239, Percent_Identity=30.1255230125523, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30554; Mature: 30554

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLDENTKAVVQGITGKQGRFHTKEMVEYNTNIVAGTSPGKAGQTVDGVPVYNSIEEIK
CEEECCCCHHHHCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
QKHPEVNASIIFIPAPFVKDAAFEAISQLDLVIIITEHLPIHDSMEIVEYAKQHNTTLIG
HHCCCCCEEEEEEECCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEC
PNTPGIITPGVGKLGIMPTHIFKKGKVGLVSRSGTLTYEVASQISAAGYGLSTAVGVGGD
CCCCCEECCCCCCCCCCHHHHHCCCCEEEEECCCCEEHHHHHHHHHCCCCCHHEECCCCC
PVTGESFTNILEKFENDPETEQIVMLGEIGGIAEVKAAKYAQENLTKPIISFIAGVSAPL
CCCCHHHHHHHHHHCCCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
GKRMGHAGAIIEGTDGTAQNKKELLKSYGVHVADIPSDIVTILNEITE
HHHCCCCCCEEECCCCCCHHHHHHHHHHCCEEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MILLDENTKAVVQGITGKQGRFHTKEMVEYNTNIVAGTSPGKAGQTVDGVPVYNSIEEIK
CEEECCCCHHHHCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
QKHPEVNASIIFIPAPFVKDAAFEAISQLDLVIIITEHLPIHDSMEIVEYAKQHNTTLIG
HHCCCCCEEEEEEECCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEC
PNTPGIITPGVGKLGIMPTHIFKKGKVGLVSRSGTLTYEVASQISAAGYGLSTAVGVGGD
CCCCCEECCCCCCCCCCHHHHHCCCCEEEEECCCCEEHHHHHHHHHCCCCCHHEECCCCC
PVTGESFTNILEKFENDPETEQIVMLGEIGGIAEVKAAKYAQENLTKPIISFIAGVSAPL
CCCCHHHHHHHHHHCCCCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
GKRMGHAGAIIEGTDGTAQNKKELLKSYGVHVADIPSDIVTILNEITE
HHHCCCCCCEEECCCCCCHHHHHHHHHHCCEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]