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The map label for this gene is rfbG [H]

Identifier: 84489342

GI number: 84489342

Start: 626597

End: 627664

Strand: Direct

Name: rfbG [H]

Synonym: Msp_0532

Alternate gene names: 84489342

Gene position: 626597-627664 (Clockwise)

Preceding gene: 84489341

Following gene: 84489343

Centisome position: 35.45

GC content: 27.9

Gene sequence:

>1068_bases
ATGGATAAATTCTTTAAAAATAAAAATATTTTACTAACAGGACATACAGGCTTTAAGGGTTCATGGTTAACAAGTATATT
AGTTAAATATGGTGCTAATGTAACAGGATACTCATTAAATCCACCATCTAATCCTAATTTATACGAATTATTAGATTTAG
ATAATGATATAAATTCAGTTATAGGTGATATAAGGGATTTAAACATGTTAAAAACCATATTTTATGATACTAATCCTTCC
ATTGTAATTCATATGGCAGCACAACCAATTGTAAGAGAAAGCTATAAAAATCCATTATATACCTACCAAACAAATGTAAT
GGGTACTGTAAATATATGTGAATGTATTAGAGAATCAAATGTTAAATCATTTCTAAATGTAACAACAGATAAAGTATATG
AAAATACTGGAAAAAATGAGGGATACTCAGAATATGAAAAACTTGATGGATATGATCCATATTCAAATAGTAAATCATGC
TCTGAAATAATAACACATTCTTATAATAATTCATTCTTTAAAGAAAAAAACATCAATACTTCAACAGCAAGAGCAGGAAA
TGTTATTGGTGGTGGAGACTTTGCAAAGGATAGAATAGTACCAGACTGTGTAAGAGCATGTATTAATAATGAAGATATTA
TTATAAGAAATCCAAATTCAATTAGACCTTATCAACATGTTTTAGAACCATTGTACATGTACTTAACAATAATAAAAAAA
CAATATGAAAATAGTGAATATGCAGGTTACTACAATGTTGGACCAGATGATGAAGACTGTATTACAACAAAAACTTTAGT
GGATATATTTTGTAGCCACTACAATAAAATCACAAACAACAACATAAAATGGATAAATAAGAGTGATAATGGTCCACATG
AGGCAACCTTCTTAAAACTTAACAACCAGAAAATAAAGGATGTCTTTGGTTGGAGGCCAACATGGAATATTAAAGAAGCT
ATTGAAAAAACAGTTGAATGGACAAATGCCTATATTAACAATGAAGATATGAAAGAATACACCAGTAATCAAATAGATGA
ATATCAAAGGAGGAATCATTATATTTAA

Upstream 100 bases:

>100_bases
TGTATGGATACAAAAAGAGATCATGATGCTTTAGAAAAATTATGGCAAGAAGATAATGCACCATGGTATTTATGGAAATA
AAGTATATAGTTGATAAATT

Downstream 100 bases:

>100_bases
AAATAAGACAGAGAAAGAAGCAAGAGAAGAAATATTACAGTTAGTAAGGGAATATGCTGATAAATATCATAAACCTGTAG
AGTATCATAGGGGAGATAAG

Product: nucleoside-diphosphate-sugar epimerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MDKFFKNKNILLTGHTGFKGSWLTSILVKYGANVTGYSLNPPSNPNLYELLDLDNDINSVIGDIRDLNMLKTIFYDTNPS
IVIHMAAQPIVRESYKNPLYTYQTNVMGTVNICECIRESNVKSFLNVTTDKVYENTGKNEGYSEYEKLDGYDPYSNSKSC
SEIITHSYNNSFFKEKNINTSTARAGNVIGGGDFAKDRIVPDCVRACINNEDIIIRNPNSIRPYQHVLEPLYMYLTIIKK
QYENSEYAGYYNVGPDDEDCITTKTLVDIFCSHYNKITNNNIKWINKSDNGPHEATFLKLNNQKIKDVFGWRPTWNIKEA
IEKTVEWTNAYINNEDMKEYTSNQIDEYQRRNHYI

Sequences:

>Translated_355_residues
MDKFFKNKNILLTGHTGFKGSWLTSILVKYGANVTGYSLNPPSNPNLYELLDLDNDINSVIGDIRDLNMLKTIFYDTNPS
IVIHMAAQPIVRESYKNPLYTYQTNVMGTVNICECIRESNVKSFLNVTTDKVYENTGKNEGYSEYEKLDGYDPYSNSKSC
SEIITHSYNNSFFKEKNINTSTARAGNVIGGGDFAKDRIVPDCVRACINNEDIIIRNPNSIRPYQHVLEPLYMYLTIIKK
QYENSEYAGYYNVGPDDEDCITTKTLVDIFCSHYNKITNNNIKWINKSDNGPHEATFLKLNNQKIKDVFGWRPTWNIKEA
IEKTVEWTNAYINNEDMKEYTSNQIDEYQRRNHYI
>Mature_355_residues
MDKFFKNKNILLTGHTGFKGSWLTSILVKYGANVTGYSLNPPSNPNLYELLDLDNDINSVIGDIRDLNMLKTIFYDTNPS
IVIHMAAQPIVRESYKNPLYTYQTNVMGTVNICECIRESNVKSFLNVTTDKVYENTGKNEGYSEYEKLDGYDPYSNSKSC
SEIITHSYNNSFFKEKNINTSTARAGNVIGGGDFAKDRIVPDCVRACINNEDIIIRNPNSIRPYQHVLEPLYMYLTIIKK
QYENSEYAGYYNVGPDDEDCITTKTLVDIFCSHYNKITNNNIKWINKSDNGPHEATFLKLNNQKIKDVFGWRPTWNIKEA
IEKTVEWTNAYINNEDMKEYTSNQIDEYQRRNHYI

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7657641, Length=330, Percent_Identity=26.0606060606061, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI48994969, Length=363, Percent_Identity=21.4876033057851, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786974, Length=357, Percent_Identity=21.8487394957983, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013445
- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =4.2.1.45 [H]

Molecular weight: Translated: 40978; Mature: 40978

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFFKNKNILLTGHTGFKGSWLTSILVKYGANVTGYSLNPPSNPNLYELLDLDNDINSV
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCCCHHHHH
IGDIRDLNMLKTIFYDTNPSIVIHMAAQPIVRESYKNPLYTYQTNVMGTVNICECIRESN
HHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCC
VKSFLNVTTDKVYENTGKNEGYSEYEKLDGYDPYSNSKSCSEIITHSYNNSFFKEKNINT
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
STARAGNVIGGGDFAKDRIVPDCVRACINNEDIIIRNPNSIRPYQHVLEPLYMYLTIIKK
CHHCCCCCCCCCCCHHHCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
QYENSEYAGYYNVGPDDEDCITTKTLVDIFCSHYNKITNNNIKWINKSDNGPHEATFLKL
HHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEE
NNQKIKDVFGWRPTWNIKEAIEKTVEWTNAYINNEDMKEYTSNQIDEYQRRNHYI
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDKFFKNKNILLTGHTGFKGSWLTSILVKYGANVTGYSLNPPSNPNLYELLDLDNDINSV
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCCCHHHHH
IGDIRDLNMLKTIFYDTNPSIVIHMAAQPIVRESYKNPLYTYQTNVMGTVNICECIRESN
HHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCC
VKSFLNVTTDKVYENTGKNEGYSEYEKLDGYDPYSNSKSCSEIITHSYNNSFFKEKNINT
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
STARAGNVIGGGDFAKDRIVPDCVRACINNEDIIIRNPNSIRPYQHVLEPLYMYLTIIKK
CHHCCCCCCCCCCCHHHCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
QYENSEYAGYYNVGPDDEDCITTKTLVDIFCSHYNKITNNNIKWINKSDNGPHEATFLKL
HHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEE
NNQKIKDVFGWRPTWNIKEAIEKTVEWTNAYINNEDMKEYTSNQIDEYQRRNHYI
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]