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The map label for this gene is tldD [C]

Identifier: 84489214

GI number: 84489214

Start: 464833

End: 466206

Strand: Direct

Name: tldD [C]

Synonym: Msp_0402

Alternate gene names: 84489214

Gene position: 464833-466206 (Clockwise)

Preceding gene: 84489213

Following gene: 84489215

Centisome position: 26.3

GC content: 32.82

Gene sequence:

>1374_bases
GTGTCTAATGAAATAGATGTAGATTATTTTCAAAAAATAATTAAAAAATTAGAATCTAGAGTAGATTATGTAGATATAAG
AGTAGGAGATTCTACTAGTAATTCTATAGTAATGAAGGATAGTAAAATAGATAATGTGGATACTGGAATAAATTTTGCAG
TTGGAATTCGTGTACTACAAAATGGTGCATGGGGTTCAGCATTCACCTCAGATATAAATAAGGTGGAAGATGTGGCAAAT
AAAGCAACAATACTTGCAAATCAATTAAGTAGTGATGTTGAACTAACTCCGGCAAATCCACAAGAAGATACAGTTGAATC
AAAAGCAAAAATTAAGATAGATGATGTTACATTCGAAGATAAAATTAGTTGCATGAAAGAAGCAAATGATGCTGCTCAAC
TAGATGGTATACAAAGTACAAACATCACATATTCAGAAGTAGAAGGAACTAATTTACTTCTAAGTAGTGAAGGAACATGT
ATTCTTTCAAATAATAATAGAACAATCTTTTCTATGAATGCTGTTGCATCAAATGGTGAAGTTATGCAAATAGGACATAA
AAGTCTCGGTGGTGTACAGGGTTTTGAAATAATTAAAGATGCAGATTTAGAATCATTTGGAAGAAGTATTTCTGAAAAAG
CAATAGGATTACTCGATGCAAAAACACCACCATCTGGTGATTTTCCAGTTATATTAGATCCTGAACTTGCAGGAGTATTT
ATACATGAAGCACTAGGTCATGCTTCAGAGGCAGATATTATACTTCAAAATGATTCAATACTAAAGGATAAACAGGGACA
AAAGATTGGATCTGATTTAATAACTGTTGTAGATGATGCAACAAGAGAAGATGCATTTGGATATTATGCATATGATGTTG
AAGGAACTAAAACATCTAAAAATGTTCTAGTAGAAAAGGGTGTACTTAAATCAGTTCTTAGTTCACGTGAAACTGCAAAA
AAATTAGGACGTCAATCAAGTGGAAATGCAAGATCCATAATTAAAGATCAACCGATTGTACGTATGAGTAATACATATAT
CCAACCTGGAGAATCATCATTTGATGAATTAATTGAAGATATGTCAACAGGAATTTATCTTAAAGGATCTCGTGGTGGAC
AAGTAGATACTGGACGTGGAGTATTCCAATTTAATGCAGTAGAAGCATATACTATAAATAATGGTGAACTTGATGATCAT
ATAAGGGATGTATCCTTGTCTGGAAGTACATTAGATATATTAAATAATGTAACAGGAGTAGGATCTGACTTTAAATTAAG
TGTAGGGTTCTGTGGTAAAGATGGTCAAACAGCACCTGTAGGTGATGGGGGACCTCATATAAGAGTAAGTAAGGCAACTG
TTGGTGGGGTATAA

Upstream 100 bases:

>100_bases
TAGTAAAAACAATAATTTTAATATAAAAGTACTGTTTTTTATTTTAACTTAATAATAATTTTTATTTATTTATAAAAAAA
TATATGGGAGGAACAAATCA

Downstream 100 bases:

>100_bases
AAATGCAATGTGGATTATTAACTGAAAAAGAAGGTAATCTTCTTCTTAAAATAGCACGTGATAATATTCGTTGTTATCTA
GAAAATAAGGACTATCAAAT

Product: zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSNEIDVDYFQKIIKKLESRVDYVDIRVGDSTSNSIVMKDSKIDNVDTGINFAVGIRVLQNGAWGSAFTSDINKVEDVAN
KATILANQLSSDVELTPANPQEDTVESKAKIKIDDVTFEDKISCMKEANDAAQLDGIQSTNITYSEVEGTNLLLSSEGTC
ILSNNNRTIFSMNAVASNGEVMQIGHKSLGGVQGFEIIKDADLESFGRSISEKAIGLLDAKTPPSGDFPVILDPELAGVF
IHEALGHASEADIILQNDSILKDKQGQKIGSDLITVVDDATREDAFGYYAYDVEGTKTSKNVLVEKGVLKSVLSSRETAK
KLGRQSSGNARSIIKDQPIVRMSNTYIQPGESSFDELIEDMSTGIYLKGSRGGQVDTGRGVFQFNAVEAYTINNGELDDH
IRDVSLSGSTLDILNNVTGVGSDFKLSVGFCGKDGQTAPVGDGGPHIRVSKATVGGV

Sequences:

>Translated_457_residues
MSNEIDVDYFQKIIKKLESRVDYVDIRVGDSTSNSIVMKDSKIDNVDTGINFAVGIRVLQNGAWGSAFTSDINKVEDVAN
KATILANQLSSDVELTPANPQEDTVESKAKIKIDDVTFEDKISCMKEANDAAQLDGIQSTNITYSEVEGTNLLLSSEGTC
ILSNNNRTIFSMNAVASNGEVMQIGHKSLGGVQGFEIIKDADLESFGRSISEKAIGLLDAKTPPSGDFPVILDPELAGVF
IHEALGHASEADIILQNDSILKDKQGQKIGSDLITVVDDATREDAFGYYAYDVEGTKTSKNVLVEKGVLKSVLSSRETAK
KLGRQSSGNARSIIKDQPIVRMSNTYIQPGESSFDELIEDMSTGIYLKGSRGGQVDTGRGVFQFNAVEAYTINNGELDDH
IRDVSLSGSTLDILNNVTGVGSDFKLSVGFCGKDGQTAPVGDGGPHIRVSKATVGGV
>Mature_456_residues
SNEIDVDYFQKIIKKLESRVDYVDIRVGDSTSNSIVMKDSKIDNVDTGINFAVGIRVLQNGAWGSAFTSDINKVEDVANK
ATILANQLSSDVELTPANPQEDTVESKAKIKIDDVTFEDKISCMKEANDAAQLDGIQSTNITYSEVEGTNLLLSSEGTCI
LSNNNRTIFSMNAVASNGEVMQIGHKSLGGVQGFEIIKDADLESFGRSISEKAIGLLDAKTPPSGDFPVILDPELAGVFI
HEALGHASEADIILQNDSILKDKQGQKIGSDLITVVDDATREDAFGYYAYDVEGTKTSKNVLVEKGVLKSVLSSRETAKK
LGRQSSGNARSIIKDQPIVRMSNTYIQPGESSFDELIEDMSTGIYLKGSRGGQVDTGRGVFQFNAVEAYTINNGELDDHI
RDVSLSGSTLDILNNVTGVGSDFKLSVGFCGKDGQTAPVGDGGPHIRVSKATVGGV

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=469, Percent_Identity=31.5565031982942, Blast_Score=198, Evalue=8e-52,
Organism=Escherichia coli, GI1790682, Length=421, Percent_Identity=22.0902612826603, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 48954; Mature: 48823

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNEIDVDYFQKIIKKLESRVDYVDIRVGDSTSNSIVMKDSKIDNVDTGINFAVGIRVLQ
CCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEEEEE
NGAWGSAFTSDINKVEDVANKATILANQLSSDVELTPANPQEDTVESKAKIKIDDVTFED
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHCCCCEEEEECCCHHH
KISCMKEANDAAQLDGIQSTNITYSEVEGTNLLLSSEGTCILSNNNRTIFSMNAVASNGE
HHHHHHHCCCHHHHCCCCCCCCEEEECCCCEEEEECCCEEEEECCCEEEEEEEEECCCCC
VMQIGHKSLGGVQGFEIIKDADLESFGRSISEKAIGLLDAKTPPSGDFPVILDPELAGVF
EEEECCHHCCCCCCHHHHHCCCHHHHHHHHHHHHHEEEECCCCCCCCCCEEECCCHHHHH
IHEALGHASEADIILQNDSILKDKQGQKIGSDLITVVDDATREDAFGYYAYDVEGTKTSK
HHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHEECCCCCCCCCCEEEEEEECCCCCCC
NVLVEKGVLKSVLSSRETAKKLGRQSSGNARSIIKDQPIVRMSNTYIQPGESSFDELIED
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEECCCEECCCCCHHHHHHHH
MSTGIYLKGSRGGQVDTGRGVFQFNAVEAYTINNGELDDHIRDVSLSGSTLDILNNVTGV
HHCCEEEECCCCCCCCCCCCEEEECCEEEEEECCCCCCHHHHEEECCCCHHHHHHCCCCC
GSDFKLSVGFCGKDGQTAPVGDGGPHIRVSKATVGGV
CCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SNEIDVDYFQKIIKKLESRVDYVDIRVGDSTSNSIVMKDSKIDNVDTGINFAVGIRVLQ
CCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEEEEE
NGAWGSAFTSDINKVEDVANKATILANQLSSDVELTPANPQEDTVESKAKIKIDDVTFED
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHCCCCEEEEECCCHHH
KISCMKEANDAAQLDGIQSTNITYSEVEGTNLLLSSEGTCILSNNNRTIFSMNAVASNGE
HHHHHHHCCCHHHHCCCCCCCCEEEECCCCEEEEECCCEEEEECCCEEEEEEEEECCCCC
VMQIGHKSLGGVQGFEIIKDADLESFGRSISEKAIGLLDAKTPPSGDFPVILDPELAGVF
EEEECCHHCCCCCCHHHHHCCCHHHHHHHHHHHHHEEEECCCCCCCCCCEEECCCHHHHH
IHEALGHASEADIILQNDSILKDKQGQKIGSDLITVVDDATREDAFGYYAYDVEGTKTSK
HHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHEECCCCCCCCCCEEEEEEECCCCCCC
NVLVEKGVLKSVLSSRETAKKLGRQSSGNARSIIKDQPIVRMSNTYIQPGESSFDELIED
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEECCCEECCCCCHHHHHHHH
MSTGIYLKGSRGGQVDTGRGVFQFNAVEAYTINNGELDDHIRDVSLSGSTLDILNNVTGV
HHCCEEEECCCCCCCCCCCCEEEECCEEEEEECCCCCCHHHHEEECCCCHHHHHHCCCCC
GSDFKLSVGFCGKDGQTAPVGDGGPHIRVSKATVGGV
CCCEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]