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The map label for this gene is mptA

Identifier: 84489115

GI number: 84489115

Start: 355680

End: 356621

Strand: Direct

Name: mptA

Synonym: Msp_0294

Alternate gene names: 84489115

Gene position: 355680-356621 (Clockwise)

Preceding gene: 84489114

Following gene: 84489116

Centisome position: 20.12

GC content: 31.0

Gene sequence:

>942_bases
ATGACAGTTTCAGAATTTCCAGATACTCAGGATAAACAACCATCCATTCCAATATCACTAACAAGAGTTGGAGTAACAGG
TGTAAAGAAATTAATAAAAATAAAAAGAGAAGATAAACGTCCTATTATTCTAATACCAACATTTGATGCTTTTGTAGATT
TACCTAGTACTCAGAAAGGAGTACACATGTCTAGAAATCCAGAAGCTATATCTGAAATTGTTGATGAGGCTGCAAATCAA
TCGGAAATTCATCTTGAAAATATATGTGCAAATCTTGTAAAAAGATTACTTGAAAAACATGAATATGCATTACATGCAGA
AACAGAGGCAAGGGGAGAATATATTATAAATAAATTATCTCCAGTATCTAAAAGAAAAACACAGGAAACAACACATATCA
TAGCAAGAGCAATTGCTATGAAAGATGATGAGGGTAATATTTCTGTTAGAAAAATGATTGGTGCAGAAGTTATTGGAATG
ACTGTATGTCCATGTGCACAAGAATCTGTTGAAAAGGATTCTAAAGATAAATTACTGGAATTTTTAGATGAAGAAACTAC
ACAAAAAGTGTTGGATGTAGTAACATTTGCTTCTCATAATCAAAGGGGTGTTGGGACAATACTTCTTGAAGTACCAGAAA
AACAAGATGTTAATGTGGATGATTTAATAAAAATAATACAGGATGCTATGAGTTCTCCTGTTTGTGAAATATTAAAACGT
CCAGATGAAAATAGAATTGTAACAAATGCACATCAAAATCCAGTATTTGTTGAGGATTGTGTAAGAAACATGGTAATAGG
ATTACTTGAAAAATATCCTAATTTACCTGATGATTCTGTAGTTACAATTAAACAAGTAAATCAAGAAAGTATTCATCAAC
ATAATGCTTATGCTGAAAAAGTTGCATCTTTTGGTAAATTACGAGAAGAAAATAAGGAGTAG

Upstream 100 bases:

>100_bases
TAATTAGTATTATAATGATATTTTAAGAAGATTACATGAAAAAAGTATATTTTACATTTTTAATAAAAACTATTAATAGA
AACAGAGGGAGTTATAAATA

Downstream 100 bases:

>100_bases
ATAATATGGAAGTAATGGAAGTATCACGTAAAATTATGGATTATCTTGATGCATTTAAAGGTTCAAAACCTGTTGTTCAT
AATTCAGAAGCAATGATTAT

Product: GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTVSEFPDTQDKQPSIPISLTRVGVTGVKKLIKIKREDKRPIILIPTFDAFVDLPSTQKGVHMSRNPEAISEIVDEAANQ
SEIHLENICANLVKRLLEKHEYALHAETEARGEYIINKLSPVSKRKTQETTHIIARAIAMKDDEGNISVRKMIGAEVIGM
TVCPCAQESVEKDSKDKLLEFLDEETTQKVLDVVTFASHNQRGVGTILLEVPEKQDVNVDDLIKIIQDAMSSPVCEILKR
PDENRIVTNAHQNPVFVEDCVRNMVIGLLEKYPNLPDDSVVTIKQVNQESIHQHNAYAEKVASFGKLREENKE

Sequences:

>Translated_313_residues
MTVSEFPDTQDKQPSIPISLTRVGVTGVKKLIKIKREDKRPIILIPTFDAFVDLPSTQKGVHMSRNPEAISEIVDEAANQ
SEIHLENICANLVKRLLEKHEYALHAETEARGEYIINKLSPVSKRKTQETTHIIARAIAMKDDEGNISVRKMIGAEVIGM
TVCPCAQESVEKDSKDKLLEFLDEETTQKVLDVVTFASHNQRGVGTILLEVPEKQDVNVDDLIKIIQDAMSSPVCEILKR
PDENRIVTNAHQNPVFVEDCVRNMVIGLLEKYPNLPDDSVVTIKQVNQESIHQHNAYAEKVASFGKLREENKE
>Mature_312_residues
TVSEFPDTQDKQPSIPISLTRVGVTGVKKLIKIKREDKRPIILIPTFDAFVDLPSTQKGVHMSRNPEAISEIVDEAANQS
EIHLENICANLVKRLLEKHEYALHAETEARGEYIINKLSPVSKRKTQETTHIIARAIAMKDDEGNISVRKMIGAEVIGMT
VCPCAQESVEKDSKDKLLEFLDEETTQKVLDVVTFASHNQRGVGTILLEVPEKQDVNVDDLIKIIQDAMSSPVCEILKRP
DENRIVTNAHQNPVFVEDCVRNMVIGLLEKYPNLPDDSVVTIKQVNQESIHQHNAYAEKVASFGKLREENKE

Specific function: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MPTA_METST (Q2NI42)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447347.1
- ProteinModelPortal:   Q2NI42
- STRING:   Q2NI42
- GeneID:   3854941
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0294
- NMPDR:   fig|339860.6.peg.285
- eggNOG:   arNOG04823
- HOGENOM:   HBG626871
- OMA:   ILIPTFD
- ProtClustDB:   PRK13675
- BioCyc:   MSTA339860:MSP_0294-MONOMER
- HAMAP:   MF_01527_A
- InterPro:   IPR003801
- InterPro:   IPR022840
- InterPro:   IPR002042
- Gene3D:   G3DSA:3.10.270.10
- TIGRFAMs:   TIGR00294

Pfam domain/function: PF02649 DUF198

EC number: NA

Molecular weight: Translated: 35166; Mature: 35034

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSEFPDTQDKQPSIPISLTRVGVTGVKKLIKIKREDKRPIILIPTFDAFVDLPSTQKG
CCCCCCCCCCCCCCCCCEEEEHHCHHHHHHHHHHHHCCCCCEEEEECHHHHHCCCCCCCC
VHMSRNPEAISEIVDEAANQSEIHLENICANLVKRLLEKHEYALHAETEARGEYIINKLS
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCC
PVSKRKTQETTHIIARAIAMKDDEGNISVRKMIGAEVIGMTVCPCAQESVEKDSKDKLLE
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCHHHHCCCCHHHHHH
FLDEETTQKVLDVVTFASHNQRGVGTILLEVPEKQDVNVDDLIKIIQDAMSSPVCEILKR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHC
PDENRIVTNAHQNPVFVEDCVRNMVIGLLEKYPNLPDDSVVTIKQVNQESIHQHNAYAEK
CCCCCEEECCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCHHHHHHHHHHHHH
VASFGKLREENKE
HHHHHHHHHCCCC
>Mature Secondary Structure 
TVSEFPDTQDKQPSIPISLTRVGVTGVKKLIKIKREDKRPIILIPTFDAFVDLPSTQKG
CCCCCCCCCCCCCCCCEEEEHHCHHHHHHHHHHHHCCCCCEEEEECHHHHHCCCCCCCC
VHMSRNPEAISEIVDEAANQSEIHLENICANLVKRLLEKHEYALHAETEARGEYIINKLS
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHCC
PVSKRKTQETTHIIARAIAMKDDEGNISVRKMIGAEVIGMTVCPCAQESVEKDSKDKLLE
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCHHHHCCCCHHHHHH
FLDEETTQKVLDVVTFASHNQRGVGTILLEVPEKQDVNVDDLIKIIQDAMSSPVCEILKR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHC
PDENRIVTNAHQNPVFVEDCVRNMVIGLLEKYPNLPDDSVVTIKQVNQESIHQHNAYAEK
CCCCCEEECCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCHHHHHHHHHHHHH
VASFGKLREENKE
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA