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The map label for this gene is fwdA

Identifier: 84489071

GI number: 84489071

Start: 301858

End: 303579

Strand: Direct

Name: fwdA

Synonym: Msp_0244

Alternate gene names: 84489071

Gene position: 301858-303579 (Clockwise)

Preceding gene: 84489070

Following gene: 84489072

Centisome position: 17.08

GC content: 33.8

Gene sequence:

>1722_bases
ATGGAATATATTTTAAAAAATGGTATTGTATTTGATCCAGCAAATAATATTGATGGAGAAAAAAAGGACATACTAATAAA
AGATGGATACATAGTTAGTGAAGTATCAAAGGATGCAAAGATTATAGATGTTACAAATAAATTAGTAATGCCTGGAGGAG
TAGATTTACACTCACACATAGCAGGACCAAAACTATCAGTGGGAAGATTATATCGTCCAGAAGATACAAGACGTGGAATA
AAACCTGCACCATGTGGTGCTATTGAGGGATTTGAAGCAGGATTTTCCATACCAACATGTCCAACAACTGGGTACAGGTA
TACTCGTATGGGATATACAACAGTAACAGAAGCAGCAGTACCACCCTTAGAGGCAAAACATGCACATGAAGAAATAAACA
GTATTCCAAACCTTGATATACCAACATTAACACTCTTTGGTAATAACTGGTTCATGCTTAAATATGTTAAGGAAAATAAC
TTAGAAAAACTAGCTTTATTCATATCAAAATGGTTGAAACTAGCAAAGGGTTATGGAATTAAAATAGTAAATCCATGTGG
AAGTGAAGCATGGGGTTGGGGAAAAAATGTAGATGGACTTGATGATCCAGAACCACACTGGGGTGTAACAGGACGTCAAG
TAATACAGGCTCTAACTAAAGTAAATGAAAAATTAGGTTTACCCCATTCTGTGCATGTTCATACAAATGACCTTGGACAT
CCTGGAAACTATGAAACAACACTTGAAACATTTGATTGTGTAAAGGATATTAAGAAAAATAAGAATGTAACAAGAGATCA
AGTGTTACATGCAACACACGTACAGTTCCATGCATATAAGGGAACATCATGGAGGGATGTTACATCAGGTGCACCAGAAT
TGATTGATTATATAAATAAGTCAAAACATATGACTTGTGATATTGGACAGATAACCTTCGATGAAACAACAACAATGACT
GCAGATGCACCAATGGAGTATGATTTATACAGACTAACAGGACTTAAATGGGCAAATAAGGATATAGAGGTTGAAACTTC
ATCTGGACTTATTCCATCAATATATTCTAAACGAGCACCAGTAAGTGTACTTCAATGGGCTATTGGGCTTGAATTCTTCC
TTGGAATAAAAGATCCATGGAAATTGGCATTAACAACTGATTCACCAAATGGTGGTCCATTTATCAGATATCCACGTGTA
ATTTCATGGATAATGAGTAATGAAAAACTAAATGATATGCTTGATAATCAAGTACATAGTTGGGCAACAAGAAGAACATC
ACTTGGAAGTTATGATAGGGAATATTCCTGGAATGAAATAGCAACAATTACAAGGGCAAGTCCAGCAAAAATACTTGGAT
TAACAGATAGAGGACATCTTGGTGTAGGTGCAAAGGCTGATGTTTCAGTATATGATATAGATGTCTATGACTTTGATACA
ACACTTCTTAAAAATTCACAAACACTTGAAAACAAGTTATTAAACAGTTTATACACTATAAAAGATGGTATGATCATGGT
TGATCATGGAAAAATTGTTAAATTAGTAGATAGTAAACATATATGGACTAATGTTTGTGGCTTAGAAAAAGAAGAGGCTA
ATCTTGTAGATGAAATAACACCAGAATTTAATAAGTATTATACTATAAAATATGAAAATTATGGTGTTCCAGATCATTAT
ATAAAACCTGATACTTGTGTAGATATAGAATATGAGGATTAG

Upstream 100 bases:

>100_bases
GTTATTGAAAAACCTGAAAACTGTCATTCAGATCAATGGATACTCTCCCAGATATACAATAGAATAGAAAAACTAAAACA
AGAAAATGGAGATAACTAAC

Downstream 100 bases:

>100_bases
ATATGAGAACTATTAAATTATTTATGAAAAAATTCAGTAAAATACCACTTGAATTTGATAATATACTTCCAGAAAAATTA
TATGATAAAACACAAAAACA

Product: hypothetical protein

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MEYILKNGIVFDPANNIDGEKKDILIKDGYIVSEVSKDAKIIDVTNKLVMPGGVDLHSHIAGPKLSVGRLYRPEDTRRGI
KPAPCGAIEGFEAGFSIPTCPTTGYRYTRMGYTTVTEAAVPPLEAKHAHEEINSIPNLDIPTLTLFGNNWFMLKYVKENN
LEKLALFISKWLKLAKGYGIKIVNPCGSEAWGWGKNVDGLDDPEPHWGVTGRQVIQALTKVNEKLGLPHSVHVHTNDLGH
PGNYETTLETFDCVKDIKKNKNVTRDQVLHATHVQFHAYKGTSWRDVTSGAPELIDYINKSKHMTCDIGQITFDETTTMT
ADAPMEYDLYRLTGLKWANKDIEVETSSGLIPSIYSKRAPVSVLQWAIGLEFFLGIKDPWKLALTTDSPNGGPFIRYPRV
ISWIMSNEKLNDMLDNQVHSWATRRTSLGSYDREYSWNEIATITRASPAKILGLTDRGHLGVGAKADVSVYDIDVYDFDT
TLLKNSQTLENKLLNSLYTIKDGMIMVDHGKIVKLVDSKHIWTNVCGLEKEEANLVDEITPEFNKYYTIKYENYGVPDHY
IKPDTCVDIEYED

Sequences:

>Translated_573_residues
MEYILKNGIVFDPANNIDGEKKDILIKDGYIVSEVSKDAKIIDVTNKLVMPGGVDLHSHIAGPKLSVGRLYRPEDTRRGI
KPAPCGAIEGFEAGFSIPTCPTTGYRYTRMGYTTVTEAAVPPLEAKHAHEEINSIPNLDIPTLTLFGNNWFMLKYVKENN
LEKLALFISKWLKLAKGYGIKIVNPCGSEAWGWGKNVDGLDDPEPHWGVTGRQVIQALTKVNEKLGLPHSVHVHTNDLGH
PGNYETTLETFDCVKDIKKNKNVTRDQVLHATHVQFHAYKGTSWRDVTSGAPELIDYINKSKHMTCDIGQITFDETTTMT
ADAPMEYDLYRLTGLKWANKDIEVETSSGLIPSIYSKRAPVSVLQWAIGLEFFLGIKDPWKLALTTDSPNGGPFIRYPRV
ISWIMSNEKLNDMLDNQVHSWATRRTSLGSYDREYSWNEIATITRASPAKILGLTDRGHLGVGAKADVSVYDIDVYDFDT
TLLKNSQTLENKLLNSLYTIKDGMIMVDHGKIVKLVDSKHIWTNVCGLEKEEANLVDEITPEFNKYYTIKYENYGVPDHY
IKPDTCVDIEYED
>Mature_573_residues
MEYILKNGIVFDPANNIDGEKKDILIKDGYIVSEVSKDAKIIDVTNKLVMPGGVDLHSHIAGPKLSVGRLYRPEDTRRGI
KPAPCGAIEGFEAGFSIPTCPTTGYRYTRMGYTTVTEAAVPPLEAKHAHEEINSIPNLDIPTLTLFGNNWFMLKYVKENN
LEKLALFISKWLKLAKGYGIKIVNPCGSEAWGWGKNVDGLDDPEPHWGVTGRQVIQALTKVNEKLGLPHSVHVHTNDLGH
PGNYETTLETFDCVKDIKKNKNVTRDQVLHATHVQFHAYKGTSWRDVTSGAPELIDYINKSKHMTCDIGQITFDETTTMT
ADAPMEYDLYRLTGLKWANKDIEVETSSGLIPSIYSKRAPVSVLQWAIGLEFFLGIKDPWKLALTTDSPNGGPFIRYPRV
ISWIMSNEKLNDMLDNQVHSWATRRTSLGSYDREYSWNEIATITRASPAKILGLTDRGHLGVGAKADVSVYDIDVYDFDT
TLLKNSQTLENKLLNSLYTIKDGMIMVDHGKIVKLVDSKHIWTNVCGLEKEEANLVDEITPEFNKYYTIKYENYGVPDHY
IKPDTCVDIEYED

Specific function: Unknown

COG id: COG1229

COG function: function code C; Formylmethanofuran dehydrogenase subunit A

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR012027
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: 1.2.99.5

Molecular weight: Translated: 64424; Mature: 64424

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYILKNGIVFDPANNIDGEKKDILIKDGYIVSEVSKDAKIIDVTNKLVMPGGVDLHSHI
CCEEECCCEEECCCCCCCCCCCEEEEECCEEEECCCCCCEEEEECCCEECCCCCCHHHHC
AGPKLSVGRLYRPEDTRRGIKPAPCGAIEGFEAGFSIPTCPTTGYRYTRMGYTTVTEAAV
CCCCCCCCCEECCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEHHHCC
PPLEAKHAHEEINSIPNLDIPTLTLFGNNWFMLKYVKENNLEKLALFISKWLKLAKGYGI
CCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCE
KIVNPCGSEAWGWGKNVDGLDDPEPHWGVTGRQVIQALTKVNEKLGLPHSVHVHTNDLGH
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
PGNYETTLETFDCVKDIKKNKNVTRDQVLHATHVQFHAYKGTSWRDVTSGAPELIDYINK
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEEEEEEEECCCCCCCCCCCCHHHHHHHCC
SKHMTCDIGQITFDETTTMTADAPMEYDLYRLTGLKWANKDIEVETSSGLIPSIYSKRAP
CCCEEEECCEEEECCCEEEECCCCCCCEEEEEECCEECCCCEEEECCCCCCHHHHCCCCC
VSVLQWAIGLEFFLGIKDPWKLALTTDSPNGGPFIRYPRVISWIMSNEKLNDMLDNQVHS
HHHHHHHHHHHHEECCCCCEEEEEEECCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHH
WATRRTSLGSYDREYSWNEIATITRASPAKILGLTDRGHLGVGAKADVSVYDIDVYDFDT
HHHHHCCCCCCCCCCCCCHHEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEECCH
TLLKNSQTLENKLLNSLYTIKDGMIMVDHGKIVKLVDSKHIWTNVCGLEKEEANLVDEIT
HHHCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCHHHHHCCCCHHHHHHHHHCC
PEFNKYYTIKYENYGVPDHYIKPDTCVDIEYED
CCCCCEEEEEEECCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MEYILKNGIVFDPANNIDGEKKDILIKDGYIVSEVSKDAKIIDVTNKLVMPGGVDLHSHI
CCEEECCCEEECCCCCCCCCCCEEEEECCEEEECCCCCCEEEEECCCEECCCCCCHHHHC
AGPKLSVGRLYRPEDTRRGIKPAPCGAIEGFEAGFSIPTCPTTGYRYTRMGYTTVTEAAV
CCCCCCCCCEECCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEHHHCC
PPLEAKHAHEEINSIPNLDIPTLTLFGNNWFMLKYVKENNLEKLALFISKWLKLAKGYGI
CCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCE
KIVNPCGSEAWGWGKNVDGLDDPEPHWGVTGRQVIQALTKVNEKLGLPHSVHVHTNDLGH
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
PGNYETTLETFDCVKDIKKNKNVTRDQVLHATHVQFHAYKGTSWRDVTSGAPELIDYINK
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEEEEEEEECCCCCCCCCCCCHHHHHHHCC
SKHMTCDIGQITFDETTTMTADAPMEYDLYRLTGLKWANKDIEVETSSGLIPSIYSKRAP
CCCEEEECCEEEECCCEEEECCCCCCCEEEEEECCEECCCCEEEECCCCCCHHHHCCCCC
VSVLQWAIGLEFFLGIKDPWKLALTTDSPNGGPFIRYPRVISWIMSNEKLNDMLDNQVHS
HHHHHHHHHHHHEECCCCCEEEEEEECCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHH
WATRRTSLGSYDREYSWNEIATITRASPAKILGLTDRGHLGVGAKADVSVYDIDVYDFDT
HHHHHCCCCCCCCCCCCCHHEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEEEEEECCH
TLLKNSQTLENKLLNSLYTIKDGMIMVDHGKIVKLVDSKHIWTNVCGLEKEEANLVDEIT
HHHCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCHHHHHCCCCHHHHHHHHHCC
PEFNKYYTIKYENYGVPDHYIKPDTCVDIEYED
CCCCCEEEEEEECCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]