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The map label for this gene is fwdB

Identifier: 84489070

GI number: 84489070

Start: 300513

End: 301856

Strand: Direct

Name: fwdB

Synonym: Msp_0243

Alternate gene names: 84489070

Gene position: 300513-301856 (Clockwise)

Preceding gene: 84489069

Following gene: 84489071

Centisome position: 17.0

GC content: 33.56

Gene sequence:

>1344_bases
TTGACGCAAATGCCAATTACTGATTATGATAGACAAGTAAAAAATTGTTCCTGTTCATACTGTGGAAATAATTGTGATGA
TATTACATACCTACTAAAGGATGATAAAATAGTGGGAGTAAGACATGCATGTAGACTAGGTGCTAGTAAAATAATAAATG
ATGAAGATCAAAGATTACTAAATCCTATGATTAGAAACAAAGAAGGAATACTTAAGGAAACAACATGGGAAAATGCACTA
GATAAAATAGCACAACTTCTAACAAACAGTGTACGTCCAGTACTATATGGTTGGGGAGAAACATCTGTTGAAGCAATAAA
AGAGGGAATAAAAATAGCACAAATAACAGGAAGTGTAATAGATAATCAGTCAACAATATGTCATGGTGCAACAATCCAAG
CATTTCAAAATGTGGGACATCCTGTTATGACACTTGGAGCTGTAAAAAACAGGGCAGATGTAATAATATATGTTGGAACA
AATCCAATGGATGATCATCCAAGACATCTTTCACGTTACACAACCTTTCCAGAAGGATTTTTCAGACCAAATGGTCGGGA
GGATAGAACAATAATAACAATAGATCCAAAATATACAAACACGGCTAAAGTATCAGATAAATGGATTAGCTATGATATAG
GGGAAGACTATGCCTTTTTTAATACTCTACGTATGATACTTGCAGGACATGAAATAACTGATGAAGAAATTGCAGGAGTT
AATATAGAAATATTGTATGAACTTGTAGAAATAATGAAAAATGCAGAATATGGTGCATTGTTCTTTGGATTAGGTCTTAC
ACAAAGTACTACAAAACAGGGAAATGTTGATGTTCTAATACAACTAATAGAAGATCTAAATAAATACTCAAAATGGTCCA
TGTTACCTATGAGGGGATTTTTCAATGTTAATGGATTTAATATGGCATTAACAACAGAAACAGGATATCCATATGGTGTG
GATTATTCAAGAGGATATCCAAGATACATGGTTGGAGAAACAACAACAATAGATCTTTTAAATCGTAGAGAACCTGATTT
TTTCATGGCAGTAGCAGCAGATCCTGGAGTTCAATTTCCAGGTTACACAATCAAACACTTAGTTGACATACCAGTTGTAC
AAGTAGATACTCATTGGGGCCCATACACTGAACTTGCAGACATAGTACTTCCAAGTACAAGAGTAGGTGTGGAAACAAAA
GGGACAGCTTATAGGATGGATTCAATACCATTATATATGAAAAAAGTTATTGAAAAACCTGAAAACTGTCATTCAGATCA
ATGGATACTCTCCCAGATATACAATAGAATAGAAAAACTAAAACAAGAAAATGGAGATAACTAA

Upstream 100 bases:

>100_bases
TCGTAGCAAATCTAATGCATAAAACATACAATAAATATAAATATAACACAAAAACTCTTGGACAAAAGCCAGTATATAAA
AAAATAGGGGAGTAAATAAT

Downstream 100 bases:

>100_bases
CATGGAATATATTTTAAAAAATGGTATTGTATTTGATCCAGCAAATAATATTGATGGAGAAAAAAAGGACATACTAATAA
AAGATGGATACATAGTTAGT

Product: FwdB

Products: NA

Alternate protein names: Tungsten-containing formylmethanofuran dehydrogenase II subunit B [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTQMPITDYDRQVKNCSCSYCGNNCDDITYLLKDDKIVGVRHACRLGASKIINDEDQRLLNPMIRNKEGILKETTWENAL
DKIAQLLTNSVRPVLYGWGETSVEAIKEGIKIAQITGSVIDNQSTICHGATIQAFQNVGHPVMTLGAVKNRADVIIYVGT
NPMDDHPRHLSRYTTFPEGFFRPNGREDRTIITIDPKYTNTAKVSDKWISYDIGEDYAFFNTLRMILAGHEITDEEIAGV
NIEILYELVEIMKNAEYGALFFGLGLTQSTTKQGNVDVLIQLIEDLNKYSKWSMLPMRGFFNVNGFNMALTTETGYPYGV
DYSRGYPRYMVGETTTIDLLNRREPDFFMAVAADPGVQFPGYTIKHLVDIPVVQVDTHWGPYTELADIVLPSTRVGVETK
GTAYRMDSIPLYMKKVIEKPENCHSDQWILSQIYNRIEKLKQENGDN

Sequences:

>Translated_447_residues
MTQMPITDYDRQVKNCSCSYCGNNCDDITYLLKDDKIVGVRHACRLGASKIINDEDQRLLNPMIRNKEGILKETTWENAL
DKIAQLLTNSVRPVLYGWGETSVEAIKEGIKIAQITGSVIDNQSTICHGATIQAFQNVGHPVMTLGAVKNRADVIIYVGT
NPMDDHPRHLSRYTTFPEGFFRPNGREDRTIITIDPKYTNTAKVSDKWISYDIGEDYAFFNTLRMILAGHEITDEEIAGV
NIEILYELVEIMKNAEYGALFFGLGLTQSTTKQGNVDVLIQLIEDLNKYSKWSMLPMRGFFNVNGFNMALTTETGYPYGV
DYSRGYPRYMVGETTTIDLLNRREPDFFMAVAADPGVQFPGYTIKHLVDIPVVQVDTHWGPYTELADIVLPSTRVGVETK
GTAYRMDSIPLYMKKVIEKPENCHSDQWILSQIYNRIEKLKQENGDN
>Mature_446_residues
TQMPITDYDRQVKNCSCSYCGNNCDDITYLLKDDKIVGVRHACRLGASKIINDEDQRLLNPMIRNKEGILKETTWENALD
KIAQLLTNSVRPVLYGWGETSVEAIKEGIKIAQITGSVIDNQSTICHGATIQAFQNVGHPVMTLGAVKNRADVIIYVGTN
PMDDHPRHLSRYTTFPEGFFRPNGREDRTIITIDPKYTNTAKVSDKWISYDIGEDYAFFNTLRMILAGHEITDEEIAGVN
IEILYELVEIMKNAEYGALFFGLGLTQSTTKQGNVDVLIQLIEDLNKYSKWSMLPMRGFFNVNGFNMALTTETGYPYGVD
YSRGYPRYMVGETTTIDLLNRREPDFFMAVAADPGVQFPGYTIKHLVDIPVVQVDTHWGPYTELADIVLPSTRVGVETKG
TAYRMDSIPLYMKKVIEKPENCHSDQWILSQIYNRIEKLKQENGDN

Specific function: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile [H]

COG id: COG1029

COG function: function code C; Formylmethanofuran dehydrogenase subunit B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fwdB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016457
- InterPro:   IPR006656 [H]

Pfam domain/function: PF00384 Molybdopterin [H]

EC number: =1.2.99.5 [H]

Molecular weight: Translated: 50623; Mature: 50492

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQMPITDYDRQVKNCSCSYCGNNCDDITYLLKDDKIVGVRHACRLGASKIINDEDQRLL
CCCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECHHHHHHHCHHHHCCCHHHHHH
NPMIRNKEGILKETTWENALDKIAQLLTNSVRPVLYGWGETSVEAIKEGIKIAQITGSVI
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCEEEEEECHHH
DNQSTICHGATIQAFQNVGHPVMTLGAVKNRADVIIYVGTNPMDDHPRHLSRYTTFPEGF
CCCCCEECCHHHHHHHHCCCHHEEHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCC
FRPNGREDRTIITIDPKYTNTAKVSDKWISYDIGEDYAFFNTLRMILAGHEITDEEIAGV
CCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHCCC
NIEILYELVEIMKNAEYGALFFGLGLTQSTTKQGNVDVLIQLIEDLNKYSKWSMLPMRGF
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCE
FNVNGFNMALTTETGYPYGVDYSRGYPRYMVGETTTIDLLNRREPDFFMAVAADPGVQFP
EECCCEEEEEEECCCCCCCCCCCCCCCCEECCCCEEEEHHCCCCCCEEEEEECCCCCCCC
GYTIKHLVDIPVVQVDTHWGPYTELADIVLPSTRVGVETKGTAYRMDSIPLYMKKVIEKP
CCHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHCCC
ENCHSDQWILSQIYNRIEKLKQENGDN
CCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TQMPITDYDRQVKNCSCSYCGNNCDDITYLLKDDKIVGVRHACRLGASKIINDEDQRLL
CCCCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECHHHHHHHCHHHHCCCHHHHHH
NPMIRNKEGILKETTWENALDKIAQLLTNSVRPVLYGWGETSVEAIKEGIKIAQITGSVI
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCEEEEEECHHH
DNQSTICHGATIQAFQNVGHPVMTLGAVKNRADVIIYVGTNPMDDHPRHLSRYTTFPEGF
CCCCCEECCHHHHHHHHCCCHHEEHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCC
FRPNGREDRTIITIDPKYTNTAKVSDKWISYDIGEDYAFFNTLRMILAGHEITDEEIAGV
CCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHCCC
NIEILYELVEIMKNAEYGALFFGLGLTQSTTKQGNVDVLIQLIEDLNKYSKWSMLPMRGF
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCE
FNVNGFNMALTTETGYPYGVDYSRGYPRYMVGETTTIDLLNRREPDFFMAVAADPGVQFP
EECCCEEEEEEECCCCCCCCCCCCCCCCEECCCCEEEEHHCCCCCCEEEEEECCCCCCCC
GYTIKHLVDIPVVQVDTHWGPYTELADIVLPSTRVGVETKGTAYRMDSIPLYMKKVIEKP
CCHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHCCC
ENCHSDQWILSQIYNRIEKLKQENGDN
CCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]