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The map label for this gene is wecB [H]

Identifier: 84489045

GI number: 84489045

Start: 270204

End: 271517

Strand: Direct

Name: wecB [H]

Synonym: Msp_0217

Alternate gene names: 84489045

Gene position: 270204-271517 (Clockwise)

Preceding gene: 84489044

Following gene: 84489051

Centisome position: 15.29

GC content: 29.38

Gene sequence:

>1314_bases
ATGAAAATTGGGATTGTACTTGGAACTAGACCTGAAATAATTAAAATGGCGCCTGTAATTGATGAAATAAAAAGAAATAA
TTCTGAATTAGTTCTCATACACACAGGACAACATTATGATATTAACATGTCAAAACAATTTTTTATTGACCTGGATTTAC
CCTTACCTCAATATAATATTGGTATAGGCTCAAATACTGCTATTAAACAAATAAGTATCATCATATCAAAACTTGAAGAA
ATACTAAAAAAGGAAGAAGTTGACATAGTATTAGTTCAAGGAGACACAAATGCAGTATTAGCAGGAGCATTAGCTGCAAA
TAAACTTAAAATTCCTGTAGGACATGTGGAGGCAGGACTAAGATCATTTGATAAGAACATGCCCGAAGAAATAAATAGAT
TGGTTGCAGATAGTTGTTCTACACTCTACTTTGTACCAACAAAGGAAACTGGAATAAATCTATTAAATGAGGGAATCAGT
CATAAATCAATCTATGTTACAGGTAATACTGTGGTAGATGCATGTAAAAGAAACATAAATCTTGCACTTAAAAATAGTAA
GATAAAAGATGAAATAAAATTCAATAATTACATAGCACTAACACTACACAGAGCAGAAAATGTGGATGATGATGAAAGAC
TAATAAACATAGTTAATAGTCTTATTAATTTACCATATAACATAGTATTTCCAATACACCCACATACAAGAAAATCTCTT
GAAAAACTAGATTTATACAAGAAAATTGAAGAATCAGAACATATTCAAATAATAAAACCATTAGGATATCTTGACTTCCT
ATATTTAATATCACAAGCTACCCTAGCACTAACAGATTCTGGTGGAGTACAAGAAGAAGCAATAACACTTGATGTTCCAT
GTGTTACATTAAGATATAATACAGAAAGACCAGAAACAATTACATGTGGTGGAAATGTACTTGCAGGAACAGAATCAGAG
GAGATTACAAGAAATATTAGCAACATACTAAATAATGAATCAGTATATGAAAGTATGAGCAGTGCTAAAAATCCATATGG
TGATGGAGACAGTGCAAAACAAATATATTCAATAATAGAAGAACATTACAATGAAAACAACCTTAAAATAACTCGTGCAG
ATAAGATAATGGACTTTGAAGGATACTATATGTATGTTATTCAAGAGAATATTACAGTAGCAGAATATGAAAATAAAAAT
AAGGGACAAATCATTGAACAAGTATTTACTAATGGAAGGCCAGAATATATAGAAGAACAATTAAATCTAGAAAATAAAAC
AATTATAGTAAAAAAATTTGAAAATGAAGATTAA

Upstream 100 bases:

>100_bases
TAGTTATTTTTATTCTTTTATTAATTATTTCTATTATGATTATTTTAATAATAAAATATTAATTAAATACAACAAACATA
TATTAAAAATCGTGATAATT

Downstream 100 bases:

>100_bases
ATACTTTCTTTTTTCATCTTTTAAAAAAACTATTAGATAATGTTGAAATATTATTAAGGATAATTATTAAGACTTAGATT
TATTTTCAATATAATCTAAT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKIGIVLGTRPEIIKMAPVIDEIKRNNSELVLIHTGQHYDINMSKQFFIDLDLPLPQYNIGIGSNTAIKQISIIISKLEE
ILKKEEVDIVLVQGDTNAVLAGALAANKLKIPVGHVEAGLRSFDKNMPEEINRLVADSCSTLYFVPTKETGINLLNEGIS
HKSIYVTGNTVVDACKRNINLALKNSKIKDEIKFNNYIALTLHRAENVDDDERLINIVNSLINLPYNIVFPIHPHTRKSL
EKLDLYKKIEESEHIQIIKPLGYLDFLYLISQATLALTDSGGVQEEAITLDVPCVTLRYNTERPETITCGGNVLAGTESE
EITRNISNILNNESVYESMSSAKNPYGDGDSAKQIYSIIEEHYNENNLKITRADKIMDFEGYYMYVIQENITVAEYENKN
KGQIIEQVFTNGRPEYIEEQLNLENKTIIVKKFENED

Sequences:

>Translated_437_residues
MKIGIVLGTRPEIIKMAPVIDEIKRNNSELVLIHTGQHYDINMSKQFFIDLDLPLPQYNIGIGSNTAIKQISIIISKLEE
ILKKEEVDIVLVQGDTNAVLAGALAANKLKIPVGHVEAGLRSFDKNMPEEINRLVADSCSTLYFVPTKETGINLLNEGIS
HKSIYVTGNTVVDACKRNINLALKNSKIKDEIKFNNYIALTLHRAENVDDDERLINIVNSLINLPYNIVFPIHPHTRKSL
EKLDLYKKIEESEHIQIIKPLGYLDFLYLISQATLALTDSGGVQEEAITLDVPCVTLRYNTERPETITCGGNVLAGTESE
EITRNISNILNNESVYESMSSAKNPYGDGDSAKQIYSIIEEHYNENNLKITRADKIMDFEGYYMYVIQENITVAEYENKN
KGQIIEQVFTNGRPEYIEEQLNLENKTIIVKKFENED
>Mature_437_residues
MKIGIVLGTRPEIIKMAPVIDEIKRNNSELVLIHTGQHYDINMSKQFFIDLDLPLPQYNIGIGSNTAIKQISIIISKLEE
ILKKEEVDIVLVQGDTNAVLAGALAANKLKIPVGHVEAGLRSFDKNMPEEINRLVADSCSTLYFVPTKETGINLLNEGIS
HKSIYVTGNTVVDACKRNINLALKNSKIKDEIKFNNYIALTLHRAENVDDDERLINIVNSLINLPYNIVFPIHPHTRKSL
EKLDLYKKIEESEHIQIIKPLGYLDFLYLISQATLALTDSGGVQEEAITLDVPCVTLRYNTERPETITCGGNVLAGTESE
EITRNISNILNNESVYESMSSAKNPYGDGDSAKQIYSIIEEHYNENNLKITRADKIMDFEGYYMYVIQENITVAEYENKN
KGQIIEQVFTNGRPEYIEEQLNLENKTIIVKKFENED

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=377, Percent_Identity=35.2785145888594, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 49351; Mature: 49351

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGIVLGTRPEIIKMAPVIDEIKRNNSELVLIHTGQHYDINMSKQFFIDLDLPLPQYNI
CEEEEEECCCCCCEEHHHHHHHHHCCCCCEEEEECCCEEEECCCCEEEEEECCCCCCEEE
GIGSNTAIKQISIIISKLEEILKKEEVDIVLVQGDTNAVLAGALAANKLKIPVGHVEAGL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHCCCEEECCHHHHHHHH
RSFDKNMPEEINRLVADSCSTLYFVPTKETGINLLNEGISHKSIYVTGNTVVDACKRNIN
HHHHCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCEEEEECCHHHHHHHCCCE
LALKNSKIKDEIKFNNYIALTLHRAENVDDDERLINIVNSLINLPYNIVFPIHPHTRKSL
EEEECCCCCCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHH
EKLDLYKKIEESEHIQIIKPLGYLDFLYLISQATLALTDSGGVQEEAITLDVPCVTLRYN
HHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCEEEEECCCCCCCCEEEEECCEEEEEEC
TERPETITCGGNVLAGTESEEITRNISNILNNESVYESMSSAKNPYGDGDSAKQIYSIIE
CCCCCEEEECCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
EHYNENNLKITRADKIMDFEGYYMYVIQENITVAEYENKNKGQIIEQVFTNGRPEYIEEQ
HHCCCCCEEEEECCEEEECCCEEEEEEECCEEEEEECCCCCHHHHHHHHHCCCHHHHHHH
LNLENKTIIVKKFENED
HCCCCCEEEEEECCCCC
>Mature Secondary Structure
MKIGIVLGTRPEIIKMAPVIDEIKRNNSELVLIHTGQHYDINMSKQFFIDLDLPLPQYNI
CEEEEEECCCCCCEEHHHHHHHHHCCCCCEEEEECCCEEEECCCCEEEEEECCCCCCEEE
GIGSNTAIKQISIIISKLEEILKKEEVDIVLVQGDTNAVLAGALAANKLKIPVGHVEAGL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHCCCEEECCHHHHHHHH
RSFDKNMPEEINRLVADSCSTLYFVPTKETGINLLNEGISHKSIYVTGNTVVDACKRNIN
HHHHCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCEEEEECCHHHHHHHCCCE
LALKNSKIKDEIKFNNYIALTLHRAENVDDDERLINIVNSLINLPYNIVFPIHPHTRKSL
EEEECCCCCCCEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHH
EKLDLYKKIEESEHIQIIKPLGYLDFLYLISQATLALTDSGGVQEEAITLDVPCVTLRYN
HHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCEEEEECCCCCCCCEEEEECCEEEEEEC
TERPETITCGGNVLAGTESEEITRNISNILNNESVYESMSSAKNPYGDGDSAKQIYSIIE
CCCCCEEEECCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
EHYNENNLKITRADKIMDFEGYYMYVIQENITVAEYENKNKGQIIEQVFTNGRPEYIEEQ
HHCCCCCEEEEECCEEEECCCEEEEEEECCEEEEEECCCCCHHHHHHHHHCCCHHHHHHH
LNLENKTIIVKKFENED
HCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]