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The map label for this gene is mtaA4

Identifier: 84489010

GI number: 84489010

Start: 225072

End: 226085

Strand: Direct

Name: mtaA4

Synonym: Msp_0182

Alternate gene names: 84489010

Gene position: 225072-226085 (Clockwise)

Preceding gene: 84489008

Following gene: 84489012

Centisome position: 12.73

GC content: 36.39

Gene sequence:

>1014_bases
ATGGATCTTATAGAAAATTTAAAAGCAGCTTTAAATGGCGAAGAAGTAGAAAAAGTACCAGCAATAAGTGCAACAGCAGC
AGCAGTTGAAGAAGCATTCCCTGCAGCTAACGTATCCTGGCCAGAAGCACACAAAGATGCTGAACAAATGGCAAGATTAG
GTATATCCTTACACGAACAAGCAGGATTAGAATGTGCTAGAGTACCTTTCGACTTAACAGCTGAAGCAGAAGCATTTGGT
TGTGAAGTAGATTTAGGTGATATGGAAAACACTCCTACATTAAGATCACACGATATTGTAGATGATGTAGAAGACTTAGA
AGTACCTGATGACTTTGTAAACAATGGTAGATTACCTGTAATCTTAGAATCTATAGAAATCTTAAAAAATGAATACCCTG
AAGTACCTGTAATTGTAGGTATGGCTGGTCCTTTCACTTTAACTGGTCACTTATTAGGTGTAGAAGATTTAGTAAAAATG
TTAAAAACTGACAGTTTCGTAGTAGAAGACGCAGTTGAAATAGCATTAGAAGCACAAACAGAATTAGTTCAAGCTTTCAA
TGAATCTGGTGTAGATGTAATTGCTGTAGCAGACCCAACATCTTCCCCTGAATTATTAGATCCTAATGATTTCAGTGAAT
TTGCACAACCTGCATTAGAAGATTTATCTGCTGAAATGGAAACAGAAAGTATCTTACACATCTGTGGTAACTCAAGACCT
ATTCTTGAAGAAATGTTAGACTGTGGATTCAGTGGAATTTCTGTAGAAGAAGCAGTTGACATGACAGAAGCTCAACAAGT
AAGAGCAGAAACTGGTGCTGAAACTGTAATGGTAGGTAACGTCTCAACAAGTCAAACTTTATTCAGTAAACCTGTAGAAG
AAGTAAAAGCTGAAGTAACACAAGCATTAGAAAAAGGTGTAAATGTATTAGCACCAAGTTGTGGTATTGCACCTAAATCA
CCTTTAGCAAACTTAAAAGCATTCGTTGAAGCAAGAGATGAATTCTATCAATAA

Upstream 100 bases:

>100_bases
ACAATGTTGATATTTATAAACATTAAAAAATGATTGAGTTTTTTAAAATTTAATGTTAAAAACTCAGATATATTATAATA
TATTTTTAAAAGGTGAACAC

Downstream 100 bases:

>100_bases
GTAGATTAATTCTACTTTTAATCTTTTTTTATTTTTTTTTGAATACTATTTTTACAGTTTGATATTAATGGTATAGAAAA
TCTATATTCATGTAATGTTT

Product: MtaA4

Products: NA

Alternate protein names: MT2-A; Methylcobamide:CoM methyltransferase II isozyme A [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MDLIENLKAALNGEEVEKVPAISATAAAVEEAFPAANVSWPEAHKDAEQMARLGISLHEQAGLECARVPFDLTAEAEAFG
CEVDLGDMENTPTLRSHDIVDDVEDLEVPDDFVNNGRLPVILESIEILKNEYPEVPVIVGMAGPFTLTGHLLGVEDLVKM
LKTDSFVVEDAVEIALEAQTELVQAFNESGVDVIAVADPTSSPELLDPNDFSEFAQPALEDLSAEMETESILHICGNSRP
ILEEMLDCGFSGISVEEAVDMTEAQQVRAETGAETVMVGNVSTSQTLFSKPVEEVKAEVTQALEKGVNVLAPSCGIAPKS
PLANLKAFVEARDEFYQ

Sequences:

>Translated_337_residues
MDLIENLKAALNGEEVEKVPAISATAAAVEEAFPAANVSWPEAHKDAEQMARLGISLHEQAGLECARVPFDLTAEAEAFG
CEVDLGDMENTPTLRSHDIVDDVEDLEVPDDFVNNGRLPVILESIEILKNEYPEVPVIVGMAGPFTLTGHLLGVEDLVKM
LKTDSFVVEDAVEIALEAQTELVQAFNESGVDVIAVADPTSSPELLDPNDFSEFAQPALEDLSAEMETESILHICGNSRP
ILEEMLDCGFSGISVEEAVDMTEAQQVRAETGAETVMVGNVSTSQTLFSKPVEEVKAEVTQALEKGVNVLAPSCGIAPKS
PLANLKAFVEARDEFYQ
>Mature_337_residues
MDLIENLKAALNGEEVEKVPAISATAAAVEEAFPAANVSWPEAHKDAEQMARLGISLHEQAGLECARVPFDLTAEAEAFG
CEVDLGDMENTPTLRSHDIVDDVEDLEVPDDFVNNGRLPVILESIEILKNEYPEVPVIVGMAGPFTLTGHLLGVEDLVKM
LKTDSFVVEDAVEIALEAQTELVQAFNESGVDVIAVADPTSSPELLDPNDFSEFAQPALEDLSAEMETESILHICGNSRP
ILEEMLDCGFSGISVEEAVDMTEAQQVRAETGAETVMVGNVSTSQTLFSKPVEEVKAEVTQALEKGVNVLAPSCGIAPKS
PLANLKAFVEARDEFYQ

Specific function: Catalyzes the transfer of the methyl group from the methylated corrinoid cofactor of mtmC, mtbC and mttC to coenzyme M [H]

COG id: COG0407

COG function: function code H; Uroporphyrinogen-III decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uroporphyrinogen decarboxylase family. MtbA/mtaA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006360
- InterPro:   IPR000257 [H]

Pfam domain/function: PF01208 URO-D [H]

EC number: NA

Molecular weight: Translated: 36228; Mature: 36228

Theoretical pI: Translated: 3.76; Mature: 3.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLIENLKAALNGEEVEKVPAISATAAAVEEAFPAANVSWPEAHKDAEQMARLGISLHEQ
CCHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHH
AGLECARVPFDLTAEAEAFGCEVDLGDMENTPTLRSHDIVDDVEDLEVPDDFVNNGRLPV
CCCEEECCCCCCCCCHHHHCCEEECCCCCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCHH
ILESIEILKNEYPEVPVIVGMAGPFTLTGHLLGVEDLVKMLKTDSFVVEDAVEIALEAQT
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
ELVQAFNESGVDVIAVADPTSSPELLDPNDFSEFAQPALEDLSAEMETESILHICGNSRP
HHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ILEEMLDCGFSGISVEEAVDMTEAQQVRAETGAETVMVGNVSTSQTLFSKPVEEVKAEVT
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
QALEKGVNVLAPSCGIAPKSPLANLKAFVEARDEFYQ
HHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLIENLKAALNGEEVEKVPAISATAAAVEEAFPAANVSWPEAHKDAEQMARLGISLHEQ
CCHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHH
AGLECARVPFDLTAEAEAFGCEVDLGDMENTPTLRSHDIVDDVEDLEVPDDFVNNGRLPV
CCCEEECCCCCCCCCHHHHCCEEECCCCCCCCCCCCCCHHHHHHHCCCCHHHHCCCCCHH
ILESIEILKNEYPEVPVIVGMAGPFTLTGHLLGVEDLVKMLKTDSFVVEDAVEIALEAQT
HHHHHHHHHHCCCCCCEEEECCCCCCHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
ELVQAFNESGVDVIAVADPTSSPELLDPNDFSEFAQPALEDLSAEMETESILHICGNSRP
HHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ILEEMLDCGFSGISVEEAVDMTEAQQVRAETGAETVMVGNVSTSQTLFSKPVEEVKAEVT
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
QALEKGVNVLAPSCGIAPKSPLANLKAFVEARDEFYQ
HHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]