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The map label for this gene is pepP [H]

Identifier: 83721643

GI number: 83721643

Start: 1400223

End: 1402058

Strand: Reverse

Name: pepP [H]

Synonym: BTH_I1254

Alternate gene names: 83721643

Gene position: 1402058-1400223 (Counterclockwise)

Preceding gene: 83720709

Following gene: 83718864

Centisome position: 36.81

GC content: 72.55

Gene sequence:

>1836_bases
TTGTCGCCGATCATAACCGGCCGTTGCGCATTCGTTGATAATCGGCCGTCCGGCCTGTGGATGGTTTGCAACAATCGCGC
CCGCCCCGTGAGCCGGGCAACGGAGATGAAGCAGCGGTGGCAGCCGCGCGCGGTTTCGCTTCGATCGCGTTCGATCGAAG
CGCGTGCGATGGGGTCGTGCGGTTGGCTCGACTTGTGCCGATCGGGCCGCAAGTTCGCCCGGCGCCGTTCATGCCGGCGC
ATGCCGGCGGGCGCGGCGCTCGACGAAGCGCACGGCTGCAATCGCGCGCCTCCCCTGCGCGCGCGGCGCATCGTCATGCC
GCGGCGCCCCCGAAGCGCGCGCTCGCCGCGCCGCGCCGCGCCGCGCGCGCATGATCGCCGCCCCACCCGCCGCGCGCGCC
CCGCGCGACGGCGCTACAATCGCGTGATGAATCAGCCGACCGAACCCGCCATCGCCCTCGACGTCTACCGCCAGCGCCGC
GACCGCGTGCTGGCCTCGCTGCGCGCACGAGGCGGCGGCGTCGCGATCGTGCCCACCGCGCCGGAAGTCCCGCGCAATCG
CGACAGCGATTATCCGTACCGGCACGACAGCTACTTCTATTACCTGACGGGCTTCGCCGAGCCCGACGCGCTCCTCGTCC
TCGACGCGTCGGCGGCAGGCGACGCACCGCGCTCGATCCTGTTCTGCCGCGCGAAGAATCCCGAGCGCGAGATCTGGGAA
GGGTTCCATTTCGGCCCCGAAGCCGCGCGCGATGCGTTCGGCTTCGACGCGGCGTTCCCGTACGACGCGCTCGACGCCGA
GATGCCGCGCCTCATCGCCGACGCGCCCGCGCTCCACTACCGCTTCGGCGCGTCGGCGGCCTTCGACAGCCGTCTGAACG
GCTGGCTCGACGCGGTGCGCGCGCGAGCGCGTGCGGGCGTCGCCGCGCCGGGCGCCGCGTTCGATCTCGGGCCGCTCGTC
GACGACATGCGGCTCGTCAAGGACGCGCACGAGCAGGCGACCATGCGCCGCGCGGCCGACATCTCCGCGCTCGCGCACCG
CCGCGCGATGGCCGCGTGCCGCCCCGGCATCCGCGAATACGAGCTCGAGGCCGAGCTGCTCTACACGTTCCGCCGCCACG
GCGCGCAGTCGCCCGCGTACGGCTCGATCGTCGCGACGGGCGCGAACGCGTGCGTGCTTCACTATCCGGCCGGCAACGCA
ATCGTCAACGACGGCGACCTCGTCCTGATCGACGCCGCGTGCGAGCTCGACGGCTACGCCTCCGACATCACCCGCACGTT
TCCGGCGAACGGCCGCTTCTCGGGCCCGCAGCGCGCGCTCTACGACATCGTGCTCGCCGCGCAGGAAGCGGCGATCGCGG
CGACGCGCGCGGGCACCTCGTTCGACGCGCCGCACGACGCCGCAGTGCGCGTGCTTGCGCAGGGCATGCTCGACACGGGG
CTCGTGCCGAAGGCGCGCTTTGCGAGCGTCGACGACGTGATCGCCGAGCGCGCGTACACGCGCTTTTACATGCATCGCAC
CGGCCACTGGCTCGGAATGGACGTGCACGACTGCGGCGACTACCGCGAACGCGGCGCGGCGCGCGACGACGACGGCGCGC
TGCCGTCGCGCGTGCTGCATGCGGGCATGGCGCTCACGATCGAGCCGGGCCTGTACGTGCGCCCGGCCGACGACGTACCA
CAGGCATTCTGGAACGTCGGCATCCGGATCGAGGACGACGCGTTCGTCACGCCGACGGGATGCGAGCTGATCACGCGCGG
CGTGCCGGTGGCCGCCGACGAGATCGAGGCGCTGATGCGCGACGCGCAGGCGCCGAGCCCCCGCCCGCAGCCGTGA

Upstream 100 bases:

>100_bases
CAGCGAGCACGATCCGCGCCTTGCGGACGAACGGGCTGCTGAGCGAACCGATTAATTTCATCATCTGTCTTCTGTCGGGA
ATACCGCCCGAGAGTATACG

Downstream 100 bases:

>100_bases
TCCGCGCGCGCTGCTTCCTACCGAGATCCACGATTCAAGAACGATGACGACCGCCGCCTCCACGCCCGCTTTCGACTTCG
ACATCGCGATCGTCGGCGCC

Product: Xaa-Pro aminopeptidase

Products: NA

Alternate protein names: Aminoacylproline aminopeptidase; Aminopeptidase P II; APP-II; X-Pro aminopeptidase [H]

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MSPIITGRCAFVDNRPSGLWMVCNNRARPVSRATEMKQRWQPRAVSLRSRSIEARAMGSCGWLDLCRSGRKFARRRSCRR
MPAGAALDEAHGCNRAPPLRARRIVMPRRPRSARSPRRAAPRAHDRRPTRRARPARRRYNRVMNQPTEPAIALDVYRQRR
DRVLASLRARGGGVAIVPTAPEVPRNRDSDYPYRHDSYFYYLTGFAEPDALLVLDASAAGDAPRSILFCRAKNPEREIWE
GFHFGPEAARDAFGFDAAFPYDALDAEMPRLIADAPALHYRFGASAAFDSRLNGWLDAVRARARAGVAAPGAAFDLGPLV
DDMRLVKDAHEQATMRRAADISALAHRRAMAACRPGIREYELEAELLYTFRRHGAQSPAYGSIVATGANACVLHYPAGNA
IVNDGDLVLIDAACELDGYASDITRTFPANGRFSGPQRALYDIVLAAQEAAIAATRAGTSFDAPHDAAVRVLAQGMLDTG
LVPKARFASVDDVIAERAYTRFYMHRTGHWLGMDVHDCGDYRERGAARDDDGALPSRVLHAGMALTIEPGLYVRPADDVP
QAFWNVGIRIEDDAFVTPTGCELITRGVPVAADEIEALMRDAQAPSPRPQP

Sequences:

>Translated_611_residues
MSPIITGRCAFVDNRPSGLWMVCNNRARPVSRATEMKQRWQPRAVSLRSRSIEARAMGSCGWLDLCRSGRKFARRRSCRR
MPAGAALDEAHGCNRAPPLRARRIVMPRRPRSARSPRRAAPRAHDRRPTRRARPARRRYNRVMNQPTEPAIALDVYRQRR
DRVLASLRARGGGVAIVPTAPEVPRNRDSDYPYRHDSYFYYLTGFAEPDALLVLDASAAGDAPRSILFCRAKNPEREIWE
GFHFGPEAARDAFGFDAAFPYDALDAEMPRLIADAPALHYRFGASAAFDSRLNGWLDAVRARARAGVAAPGAAFDLGPLV
DDMRLVKDAHEQATMRRAADISALAHRRAMAACRPGIREYELEAELLYTFRRHGAQSPAYGSIVATGANACVLHYPAGNA
IVNDGDLVLIDAACELDGYASDITRTFPANGRFSGPQRALYDIVLAAQEAAIAATRAGTSFDAPHDAAVRVLAQGMLDTG
LVPKARFASVDDVIAERAYTRFYMHRTGHWLGMDVHDCGDYRERGAARDDDGALPSRVLHAGMALTIEPGLYVRPADDVP
QAFWNVGIRIEDDAFVTPTGCELITRGVPVAADEIEALMRDAQAPSPRPQP
>Mature_610_residues
SPIITGRCAFVDNRPSGLWMVCNNRARPVSRATEMKQRWQPRAVSLRSRSIEARAMGSCGWLDLCRSGRKFARRRSCRRM
PAGAALDEAHGCNRAPPLRARRIVMPRRPRSARSPRRAAPRAHDRRPTRRARPARRRYNRVMNQPTEPAIALDVYRQRRD
RVLASLRARGGGVAIVPTAPEVPRNRDSDYPYRHDSYFYYLTGFAEPDALLVLDASAAGDAPRSILFCRAKNPEREIWEG
FHFGPEAARDAFGFDAAFPYDALDAEMPRLIADAPALHYRFGASAAFDSRLNGWLDAVRARARAGVAAPGAAFDLGPLVD
DMRLVKDAHEQATMRRAADISALAHRRAMAACRPGIREYELEAELLYTFRRHGAQSPAYGSIVATGANACVLHYPAGNAI
VNDGDLVLIDAACELDGYASDITRTFPANGRFSGPQRALYDIVLAAQEAAIAATRAGTSFDAPHDAAVRVLAQGMLDTGL
VPKARFASVDDVIAERAYTRFYMHRTGHWLGMDVHDCGDYRERGAARDDDGALPSRVLHAGMALTIEPGLYVRPADDVPQ
AFWNVGIRIEDDAFVTPTGCELITRGVPVAADEIEALMRDAQAPSPRPQP

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=501, Percent_Identity=29.7405189620758, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI149589008, Length=487, Percent_Identity=29.5687885010267, Blast_Score=179, Evalue=9e-45,
Organism=Homo sapiens, GI260593665, Length=310, Percent_Identity=36.1290322580645, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI260593663, Length=496, Percent_Identity=27.0161290322581, Blast_Score=142, Evalue=6e-34,
Organism=Escherichia coli, GI1789275, Length=442, Percent_Identity=42.9864253393665, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI1788728, Length=268, Percent_Identity=32.4626865671642, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790282, Length=297, Percent_Identity=30.3030303030303, Blast_Score=94, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17508215, Length=482, Percent_Identity=30.2904564315353, Blast_Score=192, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI71989583, Length=383, Percent_Identity=28.7206266318538, Blast_Score=129, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320922, Length=422, Percent_Identity=27.2511848341232, Blast_Score=173, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6321118, Length=475, Percent_Identity=28.2105263157895, Blast_Score=161, Evalue=4e-40,
Organism=Drosophila melanogaster, GI19920384, Length=479, Percent_Identity=33.8204592901879, Blast_Score=224, Evalue=2e-58,
Organism=Drosophila melanogaster, GI21357079, Length=497, Percent_Identity=29.9798792756539, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR007865
- InterPro:   IPR001131 [H]

Pfam domain/function: PF05195 AMP_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.11.9 [H]

Molecular weight: Translated: 67333; Mature: 67202

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPIITGRCAFVDNRPSGLWMVCNNRARPVSRATEMKQRWQPRAVSLRSRSIEARAMGSC
CCCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCC
GWLDLCRSGRKFARRRSCRRMPAGAALDEAHGCNRAPPLRARRIVMPRRPRSARSPRRAA
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHEECCCCCCCCCCCCCCCC
PRAHDRRPTRRARPARRRYNRVMNQPTEPAIALDVYRQRRDRVLASLRARGGGVAIVPTA
CCCCCCCCCHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
PEVPRNRDSDYPYRHDSYFYYLTGFAEPDALLVLDASAAGDAPRSILFCRAKNPEREIWE
CCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHC
GFHFGPEAARDAFGFDAAFPYDALDAEMPRLIADAPALHYRFGASAAFDSRLNGWLDAVR
CCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHH
ARARAGVAAPGAAFDLGPLVDDMRLVKDAHEQATMRRAADISALAHRRAMAACRPGIREY
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ELEAELLYTFRRHGAQSPAYGSIVATGANACVLHYPAGNAIVNDGDLVLIDAACELDGYA
HHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCCCEEECCCCEEEEEECCCCCCCH
SDITRTFPANGRFSGPQRALYDIVLAAQEAAIAATRAGTSFDAPHDAAVRVLAQGMLDTG
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
LVPKARFASVDDVIAERAYTRFYMHRTGHWLGMDVHDCGDYRERGAARDDDGALPSRVLH
CCCCHHHCCHHHHHHHHHHHHHHHHHCCCEEECCHHHCCCHHHCCCCCCCCCCCHHHHHH
AGMALTIEPGLYVRPADDVPQAFWNVGIRIEDDAFVTPTGCELITRGVPVAADEIEALMR
CCEEEEECCCEEEECCHHHHHHHHHCCEEECCCCEECCCCHHHHHCCCCCCHHHHHHHHH
DAQAPSPRPQP
HCCCCCCCCCC
>Mature Secondary Structure 
SPIITGRCAFVDNRPSGLWMVCNNRARPVSRATEMKQRWQPRAVSLRSRSIEARAMGSC
CCCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCC
GWLDLCRSGRKFARRRSCRRMPAGAALDEAHGCNRAPPLRARRIVMPRRPRSARSPRRAA
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHEECCCCCCCCCCCCCCCC
PRAHDRRPTRRARPARRRYNRVMNQPTEPAIALDVYRQRRDRVLASLRARGGGVAIVPTA
CCCCCCCCCHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
PEVPRNRDSDYPYRHDSYFYYLTGFAEPDALLVLDASAAGDAPRSILFCRAKNPEREIWE
CCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHC
GFHFGPEAARDAFGFDAAFPYDALDAEMPRLIADAPALHYRFGASAAFDSRLNGWLDAVR
CCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHH
ARARAGVAAPGAAFDLGPLVDDMRLVKDAHEQATMRRAADISALAHRRAMAACRPGIREY
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ELEAELLYTFRRHGAQSPAYGSIVATGANACVLHYPAGNAIVNDGDLVLIDAACELDGYA
HHHHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEECCCCEEECCCCEEEEEECCCCCCCH
SDITRTFPANGRFSGPQRALYDIVLAAQEAAIAATRAGTSFDAPHDAAVRVLAQGMLDTG
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCC
LVPKARFASVDDVIAERAYTRFYMHRTGHWLGMDVHDCGDYRERGAARDDDGALPSRVLH
CCCCHHHCCHHHHHHHHHHHHHHHHHCCCEEECCHHHCCCHHHCCCCCCCCCCCHHHHHH
AGMALTIEPGLYVRPADDVPQAFWNVGIRIEDDAFVTPTGCELITRGVPVAADEIEALMR
CCEEEEECCCEEEECCHHHHHHHHHCCEEECCCCEECCCCHHHHHCCCCCCHHHHHHHHH
DAQAPSPRPQP
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2659585; 1339425; 9278503; 9520390 [H]