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The map label for this gene is pyrR [H]

Identifier: 83721370

GI number: 83721370

Start: 1659504

End: 1660022

Strand: Direct

Name: pyrR [H]

Synonym: BTH_I1464

Alternate gene names: 83721370

Gene position: 1659504-1660022 (Clockwise)

Preceding gene: 83718957

Following gene: 83720934

Centisome position: 43.57

GC content: 73.22

Gene sequence:

>519_bases
ATGAGTTCAATTGACGCCGAGGCGCTTTATCGCGTCCTGCTCGACCAGATTCGCGGCGCCTATGGCGGCACCGCGTTCGC
CGATGCCGGCGGCCCCGTGCTCGCCGGCATCCACAGTGGCGGCGCGTGGCTCGCCGAGCGCCTCGCGCGCGACCTCGGCG
CGCCGGAATTCGGCGTCGTCAACGTCGCGCTGCATCGCGACGATTACGCGAAGAAGGGGCTGCACAGCCAGGCGAGCCCG
ACGTCGCTGCCGTTCGAGGTCGAAGGGCGGCGCATCGTGCTCGTCGACGACGTGCTGTACACCGGGCGCACGGTGCGCGC
GGCGCTCAACGAGCTGTACGACTACGGGCGGCCGGCGGCCGTGGAGCTCGCGGTGCTCGCCGATCGCGGCGGGCGCGAGC
TGCCGGTCGCGGCGCGCTTCGTGGGCGGCACGCTCGCCGTCGACGCCGACGCGACGCTCGTGCTCGAGCGCGCGGACGCG
GGACGATTCACGCTTCGCACCGAGGCGCGCGCCGGCTGA

Upstream 100 bases:

>100_bases
CGCGCCGGCCTGCGCGCGCGCGGCGACGCCGCGAATCGCGTCGACGCCGAAGCCGCCCGCGTCATTCTTCAACAATTCCT
CGACGGATTGCCCGATCAAC

Downstream 100 bases:

>100_bases
CGCGCGCGACGCATTCCGGCCGCCCGCGCGCATCGCGCATCCGGGCGCCGTTTGGCAACACGTTGGAATCACGCACATCA
TGACGACCGACACCTCCGGC

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MSSIDAEALYRVLLDQIRGAYGGTAFADAGGPVLAGIHSGGAWLAERLARDLGAPEFGVVNVALHRDDYAKKGLHSQASP
TSLPFEVEGRRIVLVDDVLYTGRTVRAALNELYDYGRPAAVELAVLADRGGRELPVAARFVGGTLAVDADATLVLERADA
GRFTLRTEARAG

Sequences:

>Translated_172_residues
MSSIDAEALYRVLLDQIRGAYGGTAFADAGGPVLAGIHSGGAWLAERLARDLGAPEFGVVNVALHRDDYAKKGLHSQASP
TSLPFEVEGRRIVLVDDVLYTGRTVRAALNELYDYGRPAAVELAVLADRGGRELPVAARFVGGTLAVDADATLVLERADA
GRFTLRTEARAG
>Mature_171_residues
SSIDAEALYRVLLDQIRGAYGGTAFADAGGPVLAGIHSGGAWLAERLARDLGAPEFGVVNVALHRDDYAKKGLHSQASPT
SLPFEVEGRRIVLVDDVLYTGRTVRAALNELYDYGRPAAVELAVLADRGGRELPVAARFVGGTLAVDADATLVLERADAG
RFTLRTEARAG

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 18177; Mature: 18046

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIDAEALYRVLLDQIRGAYGGTAFADAGGPVLAGIHSGGAWLAERLARDLGAPEFGVV
CCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCCCEE
NVALHRDDYAKKGLHSQASPTSLPFEVEGRRIVLVDDVLYTGRTVRAALNELYDYGRPAA
EEEEECCHHHHHCCCCCCCCCCCCEEECCCEEEEECCCHHCCHHHHHHHHHHHHCCCCCC
VELAVLADRGGRELPVAARFVGGTLAVDADATLVLERADAGRFTLRTEARAG
EEEEEEECCCCCCCCHHHEECCCEEEECCCCEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure 
SSIDAEALYRVLLDQIRGAYGGTAFADAGGPVLAGIHSGGAWLAERLARDLGAPEFGVV
CCCCHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCCCEE
NVALHRDDYAKKGLHSQASPTSLPFEVEGRRIVLVDDVLYTGRTVRAALNELYDYGRPAA
EEEEECCHHHHHCCCCCCCCCCCCEEECCCEEEEECCCHHCCHHHHHHHHHHHHCCCCCC
VELAVLADRGGRELPVAARFVGGTLAVDADATLVLERADAGRFTLRTEARAG
EEEEEEECCCCCCCCHHHEECCCEEEECCCCEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]