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The map label for this gene is blh [H]

Identifier: 83721139

GI number: 83721139

Start: 2570735

End: 2571628

Strand: Reverse

Name: blh [H]

Synonym: BTH_I2282

Alternate gene names: 83721139

Gene position: 2571628-2570735 (Counterclockwise)

Preceding gene: 83721659

Following gene: 83719678

Centisome position: 67.51

GC content: 70.25

Gene sequence:

>894_bases
ATGACGGTCGAAGGCTTTTTCGACCCGGCGACCTGCACCATCAGCTATTTGCTGCTCGATTCCGGCAGCGGCGAATGCGC
GTTGATCGACAGCGTGCTCGACTACGATCCGAAATCCGGCCGCACGCGCACCGCGAGCGCGGACCAGCTGATCGCGCGCG
TCGCGGCACTCGGCGCGCGCGTGCGCTGGCTGCTCGAGACGCACGTGCACGCCGACCATCTGTCGGCCGCGCCGTACCTG
AAGGCGCGGGTCGGCGGCGAAATCGCGATCGGCCGCCACGTGACGCGCGTGCAGGACGTGTTCGGCAAGCTGTTCAACGC
GGGGCCCTCGTTCGCGCACGACGGCAGCCAGTTCGACCGCCTGCTCGACGACGGCGATACGCTCGCGCTCGGCGCGCTGT
CGATTCGCGCGATGCACACGCCCGGCCACACGCCCGCGTGCATGACCTACGTCGTCACCGAAGGGCGCGCGGCGCACGGC
GCACCCGGCGCACGAGACGCGGCCGCGTTCGTCGGCGATACGCTGTTCATGCCCGACTACGGCACCGCGCGCTGCGACTT
CCCCGGCGGCGACGCGCGCACGCTGTACCGGTCGATCCGCAAGGTGCTGAGCCTGCCGCCAGCGACGCGCCTCTACATGT
GCCACGACTATCAGCCGAACGGCCGCGCGGTGCAGTACGCGAGCACCGTCGCCAACGAGCTGCGCGAGAACGTGCACATC
CGCGAGGGCGTCACCGAGGACGACTTCGTCGCGATGCGCACCGCGCGCGACGCGACGCTCGACATGCCGGTGCTGATGCT
GCCGTCGGTGCAGGTCAACATGCGCGCGGGGCGCCTGCCCGAGCCCGAGGACAACGGCGTGCGCTACCTGAAGATCCCGC
TCGACGCGATCTGA

Upstream 100 bases:

>100_bases
GGTGATCGGCAATGCTGGCTACTTGGCACGGTTCTTGTTCAAACGATCGCCATCTCGATGAATCGGCTCCAGGAGAAATC
TCGTGACAACAGCGCCCACG

Downstream 100 bases:

>100_bases
GCGTGCCCGCCCTCCCCAACGACGACACGACACACACAACAGGCCAACCATGGAAATCCGCAAGCTGACCGACACGCTGT
CGGTCTCCCCCCAACTCGCC

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTVEGFFDPATCTISYLLLDSGSGECALIDSVLDYDPKSGRTRTASADQLIARVAALGARVRWLLETHVHADHLSAAPYL
KARVGGEIAIGRHVTRVQDVFGKLFNAGPSFAHDGSQFDRLLDDGDTLALGALSIRAMHTPGHTPACMTYVVTEGRAAHG
APGARDAAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIRKVLSLPPATRLYMCHDYQPNGRAVQYASTVANELRENVHI
REGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI

Sequences:

>Translated_297_residues
MTVEGFFDPATCTISYLLLDSGSGECALIDSVLDYDPKSGRTRTASADQLIARVAALGARVRWLLETHVHADHLSAAPYL
KARVGGEIAIGRHVTRVQDVFGKLFNAGPSFAHDGSQFDRLLDDGDTLALGALSIRAMHTPGHTPACMTYVVTEGRAAHG
APGARDAAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIRKVLSLPPATRLYMCHDYQPNGRAVQYASTVANELRENVHI
REGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI
>Mature_296_residues
TVEGFFDPATCTISYLLLDSGSGECALIDSVLDYDPKSGRTRTASADQLIARVAALGARVRWLLETHVHADHLSAAPYLK
ARVGGEIAIGRHVTRVQDVFGKLFNAGPSFAHDGSQFDRLLDDGDTLALGALSIRAMHTPGHTPACMTYVVTEGRAAHGA
PGARDAAAFVGDTLFMPDYGTARCDFPGGDARTLYRSIRKVLSLPPATRLYMCHDYQPNGRAVQYASTVANELRENVHIR
EGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=273, Percent_Identity=31.5018315018315, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17538952, Length=269, Percent_Identity=28.2527881040892, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221330176, Length=280, Percent_Identity=28.9285714285714, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32215; Mature: 32084

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEGFFDPATCTISYLLLDSGSGECALIDSVLDYDPKSGRTRTASADQLIARVAALGAR
CCCCCCCCCHHHEEEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
VRWLLETHVHADHLSAAPYLKARVGGEIAIGRHVTRVQDVFGKLFNAGPSFAHDGSQFDR
HHHHHHHHCCHHHHCCCCHHHHHCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LLDDGDTLALGALSIRAMHTPGHTPACMTYVVTEGRAAHGAPGARDAAAFVGDTLFMPDY
HHCCCCEEEEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCEEECCCC
GTARCDFPGGDARTLYRSIRKVLSLPPATRLYMCHDYQPNGRAVQYASTVANELRENVHI
CCEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHCCCH
REGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI
HCCCCCCHHEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
TVEGFFDPATCTISYLLLDSGSGECALIDSVLDYDPKSGRTRTASADQLIARVAALGAR
CCCCCCCCHHHEEEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
VRWLLETHVHADHLSAAPYLKARVGGEIAIGRHVTRVQDVFGKLFNAGPSFAHDGSQFDR
HHHHHHHHCCHHHHCCCCHHHHHCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LLDDGDTLALGALSIRAMHTPGHTPACMTYVVTEGRAAHGAPGARDAAAFVGDTLFMPDY
HHCCCCEEEEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHCCEEECCCC
GTARCDFPGGDARTLYRSIRKVLSLPPATRLYMCHDYQPNGRAVQYASTVANELRENVHI
CCEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHCCCH
REGVTEDDFVAMRTARDATLDMPVLMLPSVQVNMRAGRLPEPEDNGVRYLKIPLDAI
HCCCCCCHHEEEECCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]