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The map label for this gene is dapL [H]

Identifier: 83721055

GI number: 83721055

Start: 2282395

End: 2283657

Strand: Reverse

Name: dapL [H]

Synonym: BTH_I2017

Alternate gene names: 83721055

Gene position: 2283657-2282395 (Counterclockwise)

Preceding gene: 83719576

Following gene: 161723132

Centisome position: 59.95

GC content: 70.55

Gene sequence:

>1263_bases
GTGAGCCTCACGCCCGTGAATCCTCGTCTCGACACGCTGCAGCCCTACCCGTTCGAAAAGCTCCGCGCGCTCTTTGCCGG
CGTGACGCCAAGCGCGCATCTGCCGCCGATCAGCTTCGGCATCGGCGAGCCGAAGCACGCAACGCCCGCGCTGATCCGCG
ACGCCGCGGCCGCCGCGCTCGACGGCCTCGCGTCGTATCCGGCGACGGCGGGCACCGATGCGCTGCGCGAGGCGCTCGCG
CGCTGGCTCGAGCGGCGCTACGGGCTGCCCGCGATCGACGCGACGACGCAGGTTCTCGCCGCGTCGGGCTCGCGCGAGGC
GCTCTTCTCGCTCGCGCAGGCGGTGATCGATTCGAGCCCGCGCGGCAACCGCGACAAGCAAGGCGGCGAATGCCAAAACG
GCGAAAGGCCGATCGTACTCTGTCCGAATCCCTTCTATCAAATCTACGAAGGCGCGGCGCTCCTCGCGGGCGCCGAGCCG
TACTTCGTCAACAGCGATCCGGCGCGCAACTTCGCGCCCGATTATTCGGTCGTGCCGGCCGACGTGTGGGCGCGCACGCA
GCTCGTCTACGTGTGCTCGCCGGGCAACCCGACGGGCGCCGTGCTGACCCTCGACGACTGGCGCAAGCTCTTCGCGCTGT
CGGACGAGCACGGCTTCGTGATCGCGTCGGACGAATGCTATTCGGAGATCTACTTCGACGAGGCGAAGCCGCCGCTGGGC
GGCCTCGAGGCCGCGCACAAGCTCGGCCGCGGGTTCGAGCGCCTCGTGATGCTGTCGAGCCTGTCGAAGCGCTCGAACGT
GCCGGGCATGCGCTCGGGTTTCGTCGCGGGCGACGCGGCGCTCCTCAAGCGCTTCCTGCTGTACCGCACCTACCACGGCG
CGGCGCTGTCGCCCGTCTGGCAGAAGGCGAGCGTCGCCGCCTGGGGCGACGAGGCGCACGTGCGCGAGAACCGCGCGCTC
TACGCGCAGAAGTTCGCGACCGTCACGCCGATGCTCGCCGACGTCGTCGACGTGCGCCTGCCCGACGCCGCGTTCTACCT
GTGGGCGAACGTCGCGCGAACCGGCCTGTCGGACACCGAGTTCGCCCGGCGCCTCTACGCCGACTATAATGTGACGGTCC
TGCCCGGCTCGTATCTCGCCCGCGACGCGCACGGCGCGAATCCCGGCCGCGACTTCGTCCGGATCGCGCTCGTCGCCGGC
ACGGCCGAATGCGCCGAAGGCGCGCAGCGCATCGTCGATTTCTGCCGCGGCCTCGCCCGCTGA

Upstream 100 bases:

>100_bases
CGCCGCGCCCCTTCTTCGCCCGCGCAAGGCGGCGCCAGCCGCGCCGCCTTGCGCCCGTTTTGCTTAAACCGGCCCGTCCG
ATCGGCCATCTACCGGCTCC

Downstream 100 bases:

>100_bases
ACGCGCGTGAAGCGCCCCCGATTCATCCATCATCCACGTCCAGCATAGCCACGAACATGTCGCAACAACTTCAGCAAATC
ATCGATAACGCCTGGGAAAA

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSLTPVNPRLDTLQPYPFEKLRALFAGVTPSAHLPPISFGIGEPKHATPALIRDAAAAALDGLASYPATAGTDALREALA
RWLERRYGLPAIDATTQVLAASGSREALFSLAQAVIDSSPRGNRDKQGGECQNGERPIVLCPNPFYQIYEGAALLAGAEP
YFVNSDPARNFAPDYSVVPADVWARTQLVYVCSPGNPTGAVLTLDDWRKLFALSDEHGFVIASDECYSEIYFDEAKPPLG
GLEAAHKLGRGFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKRFLLYRTYHGAALSPVWQKASVAAWGDEAHVRENRAL
YAQKFATVTPMLADVVDVRLPDAAFYLWANVARTGLSDTEFARRLYADYNVTVLPGSYLARDAHGANPGRDFVRIALVAG
TAECAEGAQRIVDFCRGLAR

Sequences:

>Translated_420_residues
MSLTPVNPRLDTLQPYPFEKLRALFAGVTPSAHLPPISFGIGEPKHATPALIRDAAAAALDGLASYPATAGTDALREALA
RWLERRYGLPAIDATTQVLAASGSREALFSLAQAVIDSSPRGNRDKQGGECQNGERPIVLCPNPFYQIYEGAALLAGAEP
YFVNSDPARNFAPDYSVVPADVWARTQLVYVCSPGNPTGAVLTLDDWRKLFALSDEHGFVIASDECYSEIYFDEAKPPLG
GLEAAHKLGRGFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKRFLLYRTYHGAALSPVWQKASVAAWGDEAHVRENRAL
YAQKFATVTPMLADVVDVRLPDAAFYLWANVARTGLSDTEFARRLYADYNVTVLPGSYLARDAHGANPGRDFVRIALVAG
TAECAEGAQRIVDFCRGLAR
>Mature_419_residues
SLTPVNPRLDTLQPYPFEKLRALFAGVTPSAHLPPISFGIGEPKHATPALIRDAAAAALDGLASYPATAGTDALREALAR
WLERRYGLPAIDATTQVLAASGSREALFSLAQAVIDSSPRGNRDKQGGECQNGERPIVLCPNPFYQIYEGAALLAGAEPY
FVNSDPARNFAPDYSVVPADVWARTQLVYVCSPGNPTGAVLTLDDWRKLFALSDEHGFVIASDECYSEIYFDEAKPPLGG
LEAAHKLGRGFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKRFLLYRTYHGAALSPVWQKASVAAWGDEAHVRENRALY
AQKFATVTPMLADVVDVRLPDAAFYLWANVARTGLSDTEFARRLYADYNVTVLPGSYLARDAHGANPGRDFVRIALVAGT
AECAEGAQRIVDFCRGLAR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=410, Percent_Identity=22.1951219512195, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI56713254, Length=410, Percent_Identity=22.4390243902439, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI95147551, Length=285, Percent_Identity=25.2631578947368, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI169881279, Length=285, Percent_Identity=25.2631578947368, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788722, Length=416, Percent_Identity=26.2019230769231, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1786816, Length=352, Percent_Identity=25.5681818181818, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788627, Length=243, Percent_Identity=23.0452674897119, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI18859735, Length=413, Percent_Identity=25.181598062954, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 45436; Mature: 45305

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTPVNPRLDTLQPYPFEKLRALFAGVTPSAHLPPISFGIGEPKHATPALIRDAAAAAL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DGLASYPATAGTDALREALARWLERRYGLPAIDATTQVLAASGSREALFSLAQAVIDSSP
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
RGNRDKQGGECQNGERPIVLCPNPFYQIYEGAALLAGAEPYFVNSDPARNFAPDYSVVPA
CCCCCCCCCCCCCCCCCEEECCCHHHHHHCCCEEEECCCCEEECCCCCCCCCCCCCCCCH
DVWARTQLVYVCSPGNPTGAVLTLDDWRKLFALSDEHGFVIASDECYSEIYFDEAKPPLG
HHHCCEEEEEEECCCCCCEEEEEHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCCCCCCC
GLEAAHKLGRGFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKRFLLYRTYHGAALSPVW
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHH
QKASVAAWGDEAHVRENRALYAQKFATVTPMLADVVDVRLPDAAFYLWANVARTGLSDTE
HCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHH
FARRLYADYNVTVLPGSYLARDAHGANPGRDFVRIALVAGTAECAEGAQRIVDFCRGLAR
HHHHHHCCCCEEEECCHHHHCCCCCCCCCHHHEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLTPVNPRLDTLQPYPFEKLRALFAGVTPSAHLPPISFGIGEPKHATPALIRDAAAAAL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
DGLASYPATAGTDALREALARWLERRYGLPAIDATTQVLAASGSREALFSLAQAVIDSSP
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
RGNRDKQGGECQNGERPIVLCPNPFYQIYEGAALLAGAEPYFVNSDPARNFAPDYSVVPA
CCCCCCCCCCCCCCCCCEEECCCHHHHHHCCCEEEECCCCEEECCCCCCCCCCCCCCCCH
DVWARTQLVYVCSPGNPTGAVLTLDDWRKLFALSDEHGFVIASDECYSEIYFDEAKPPLG
HHHCCEEEEEEECCCCCCEEEEEHHHHHHHHHCCCCCCEEEECHHHHHHHHHCCCCCCCC
GLEAAHKLGRGFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKRFLLYRTYHGAALSPVW
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHH
QKASVAAWGDEAHVRENRALYAQKFATVTPMLADVVDVRLPDAAFYLWANVARTGLSDTE
HCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHH
FARRLYADYNVTVLPGSYLARDAHGANPGRDFVRIALVAGTAECAEGAQRIVDFCRGLAR
HHHHHHCCCCEEEECCHHHHCCCCCCCCCHHHEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA