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The map label for this gene is pmbA [H]

Identifier: 83720370

GI number: 83720370

Start: 1881432

End: 1882928

Strand: Direct

Name: pmbA [H]

Synonym: BTH_I1673

Alternate gene names: 83720370

Gene position: 1881432-1882928 (Clockwise)

Preceding gene: 83720885

Following gene: 83721278

Centisome position: 49.39

GC content: 68.8

Gene sequence:

>1497_bases
TTGTATCGCGCCGGACACCGCGCGGCCGCGCGGGCGCGCGTCGCCCGCGCCGGACCTTGCTATGATCGCGGGATACGCAC
ATTTCGAAACATGCGGGCGACCCGCCCGTTACCGGATACCACGACGATGGCTGCAAACCTCGACGCCCAGGCGCACTATT
TTCCGCACACGCAAGACGAACTGAAGGCAATCGCGACGGACATCCTCCGGCACGCGAAGGCGCTCGGCGCGACCGACGCC
GCGACCGAAATCTCCGAGGGCGACGGCCTGTCGGTGTCGGTGCGGCGCGGCGAAGTCGAGACGATCGAGCACAATCGCGA
CAAGACGGTCGGCGTGACCGTCTTCATCGGCAAGAAGCGCGGCAATGCGAGCACGTCGGATTTCTCGCCCGCGGCGCTGA
AGGACACGGTCGCGGCCGCGTACAACATCGCGCGCTTCACGGCCGAGGACGACGCGGCGGGGCTCGCCGAAGCCGAGCTG
CTCGAAACCGATCCGCGCGACCTGGACCTATATCACCCGTGGCGCCTGTCGGCCGACGATGCGGTCGACCTCGCGCGCCG
CGCGGAGGATGCCGCATTCGCGGTGAGCCCGCAAATCCGCAATTCGGAGGGAGCGAGCGTATCCGCGCAGCATTCGCAGT
TCGTGCTCGCGACGACGCGCGGCTTTCTCGCCGGCTATCCGTACTCGCGCCACTACATCGCGTGCGCGCCGATCGCGGGC
AGCGGCCGCCACATGCAGCGCGACGACTGGTACACGTCGAAGCGCCGCGCGGACGAACTCGCGTCGCCCGAATCGGTCGG
CCGCTATGCGGCGCAACGCGCGCTCGCGCGAATGGGCGCGCGCCGCCTCGACACGCGCAAGGTGCCCGTGCTGTTCGAGG
CGCCGCTCGCGGCGGGCCTGCTCGGCGCGTTCGTGCAGGCGGTGAGCGGCGGCGCGCTGTATCGGAAGACGTCGTTCCTG
GTCGACAGCCTCGGCAAGGAGGTGTTCGCGCCGCACGTGCAGATCGTCGAGGACCCGCACGTGCCGCGCGCGATGGGCAG
CGCGCCGTTCGACGAGGAGGGCGTGCGCACGCATGCGCGCAGCGTCGTCAAGGACGGCGTGGTCGAGGGCTATTTCCTGT
CGACGTATTCGGCGCGCAAGCTCGGCACGCAGACGACCGGCAACGCGGGCGGCTCGCACAACATCGCGCTCAGGAGCGCG
CTCACGAATCCCGCCGACGACTTCGACGCGATGCTCAAGAAGCTCGGCACGGGTCTTTTGCTGACCGAGCTGATGGGGCA
GGGCGTCAACTACGTGACGGGCGACTATTCGCGCGGCGCGGCGGGCTTCTGGGTCGAGAACGGCGAGATCCAGTATCCGG
TCGAGGAGATCACGGTGGCGAGCACGCTGCAGGAGATGTTCCGCCACATCGTCGCGATCGGCGCGGACTCGATCGTGCGC
GGCACGAAGGAAACGGGGTCGGTGCTGATCGAGCAGATGACGATCGCGGGGCAGTGA

Upstream 100 bases:

>100_bases
CGCTTCAACTGGGACTTGCTGGGGCGATCGTAGCCGTGGTCGGCGTCTTCGCCGGCGTGTTCGATCGGTTGGATGCGGGT
TTTGCGTGTCATGGGCGGCA

Downstream 100 bases:

>100_bases
ACGCGGCGATCGTTTCGATCGCGCAAAAGCAAGAGGCGCCGCGGCGAGCGGCGCCTTTTTTGTGTCGTCGCGCGGGAGCC
CGCGATATCGCGCGCGGGCT

Product: pmbA protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MYRAGHRAAARARVARAGPCYDRGIRTFRNMRATRPLPDTTTMAANLDAQAHYFPHTQDELKAIATDILRHAKALGATDA
ATEISEGDGLSVSVRRGEVETIEHNRDKTVGVTVFIGKKRGNASTSDFSPAALKDTVAAAYNIARFTAEDDAAGLAEAEL
LETDPRDLDLYHPWRLSADDAVDLARRAEDAAFAVSPQIRNSEGASVSAQHSQFVLATTRGFLAGYPYSRHYIACAPIAG
SGRHMQRDDWYTSKRRADELASPESVGRYAAQRALARMGARRLDTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFL
VDSLGKEVFAPHVQIVEDPHVPRAMGSAPFDEEGVRTHARSVVKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNIALRSA
LTNPADDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAGFWVENGEIQYPVEEITVASTLQEMFRHIVAIGADSIVR
GTKETGSVLIEQMTIAGQ

Sequences:

>Translated_498_residues
MYRAGHRAAARARVARAGPCYDRGIRTFRNMRATRPLPDTTTMAANLDAQAHYFPHTQDELKAIATDILRHAKALGATDA
ATEISEGDGLSVSVRRGEVETIEHNRDKTVGVTVFIGKKRGNASTSDFSPAALKDTVAAAYNIARFTAEDDAAGLAEAEL
LETDPRDLDLYHPWRLSADDAVDLARRAEDAAFAVSPQIRNSEGASVSAQHSQFVLATTRGFLAGYPYSRHYIACAPIAG
SGRHMQRDDWYTSKRRADELASPESVGRYAAQRALARMGARRLDTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFL
VDSLGKEVFAPHVQIVEDPHVPRAMGSAPFDEEGVRTHARSVVKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNIALRSA
LTNPADDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAGFWVENGEIQYPVEEITVASTLQEMFRHIVAIGADSIVR
GTKETGSVLIEQMTIAGQ
>Mature_498_residues
MYRAGHRAAARARVARAGPCYDRGIRTFRNMRATRPLPDTTTMAANLDAQAHYFPHTQDELKAIATDILRHAKALGATDA
ATEISEGDGLSVSVRRGEVETIEHNRDKTVGVTVFIGKKRGNASTSDFSPAALKDTVAAAYNIARFTAEDDAAGLAEAEL
LETDPRDLDLYHPWRLSADDAVDLARRAEDAAFAVSPQIRNSEGASVSAQHSQFVLATTRGFLAGYPYSRHYIACAPIAG
SGRHMQRDDWYTSKRRADELASPESVGRYAAQRALARMGARRLDTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFL
VDSLGKEVFAPHVQIVEDPHVPRAMGSAPFDEEGVRTHARSVVKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNIALRSA
LTNPADDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAGFWVENGEIQYPVEEITVASTLQEMFRHIVAIGADSIVR
GTKETGSVLIEQMTIAGQ

Specific function: May facilitate the secretion of the peptide antibiotic microcin B17 (MccB17) by completing its maturation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1790682, Length=426, Percent_Identity=47.887323943662, Blast_Score=407, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 53715; Mature: 53715

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRAGHRAAARARVARAGPCYDRGIRTFRNMRATRPLPDTTTMAANLDAQAHYFPHTQDE
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCHHH
LKAIATDILRHAKALGATDAATEISEGDGLSVSVRRGEVETIEHNRDKTVGVTVFIGKKR
HHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCHHHHCCCCCEEEEEEEEECCC
GNASTSDFSPAALKDTVAAAYNIARFTAEDDAAGLAEAELLETDPRDLDLYHPWRLSADD
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCH
AVDLARRAEDAAFAVSPQIRNSEGASVSAQHSQFVLATTRGFLAGYPYSRHYIACAPIAG
HHHHHHHHCCCEEEECCCCCCCCCCEEECCCCEEEEEECCHHHHCCCCCCCEEEEECCCC
SGRHMQRDDWYTSKRRADELASPESVGRYAAQRALARMGARRLDTRKVPVLFEAPLAAGL
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHH
LGAFVQAVSGGALYRKTSFLVDSLGKEVFAPHVQIVEDPHVPRAMGSAPFDEEGVRTHAR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHCCCCCCCHHHHHHHHH
SVVKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNIALRSALTNPADDFDAMLKKLGTGLL
HHHHHCCCCCEEEECCHHHHCCCCCCCCCCCCCCEEEHHHCCCCCHHHHHHHHHHCCHHH
LTELMGQGVNYVTGDYSRGAAGFWVENGEIQYPVEEITVASTLQEMFRHIVAIGADSIVR
HHHHHHCCCCEEECCCCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHC
GTKETGSVLIEQMTIAGQ
CCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYRAGHRAAARARVARAGPCYDRGIRTFRNMRATRPLPDTTTMAANLDAQAHYFPHTQDE
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCHHH
LKAIATDILRHAKALGATDAATEISEGDGLSVSVRRGEVETIEHNRDKTVGVTVFIGKKR
HHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCHHHHCCCCCEEEEEEEEECCC
GNASTSDFSPAALKDTVAAAYNIARFTAEDDAAGLAEAELLETDPRDLDLYHPWRLSADD
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCH
AVDLARRAEDAAFAVSPQIRNSEGASVSAQHSQFVLATTRGFLAGYPYSRHYIACAPIAG
HHHHHHHHCCCEEEECCCCCCCCCCEEECCCCEEEEEECCHHHHCCCCCCCEEEEECCCC
SGRHMQRDDWYTSKRRADELASPESVGRYAAQRALARMGARRLDTRKVPVLFEAPLAAGL
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHH
LGAFVQAVSGGALYRKTSFLVDSLGKEVFAPHVQIVEDPHVPRAMGSAPFDEEGVRTHAR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHCCCCCCCHHHHHHHHH
SVVKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNIALRSALTNPADDFDAMLKKLGTGLL
HHHHHCCCCCEEEECCHHHHCCCCCCCCCCCCCCEEEHHHCCCCCHHHHHHHHHHCCHHH
LTELMGQGVNYVTGDYSRGAAGFWVENGEIQYPVEEITVASTLQEMFRHIVAIGADSIVR
HHHHHHCCCCEEECCCCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHCCHHHHC
GTKETGSVLIEQMTIAGQ
CCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]