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The map label for this gene is tpiA [H]

Identifier: 83719537

GI number: 83719537

Start: 1202063

End: 1202818

Strand: Direct

Name: tpiA [H]

Synonym: BTH_I1058

Alternate gene names: 83719537

Gene position: 1202063-1202818 (Clockwise)

Preceding gene: 83720037

Following gene: 83719049

Centisome position: 31.56

GC content: 69.58

Gene sequence:

>756_bases
ATGTCGAAACAGAGAATCAAGCGGGTGATCGGCAACTGGAAGATGCACGGTCGCCTGAGCGGCAACCAGGCATTGCTGAC
GGAAGTCGCGCAGGGCGCGCAAGCGGTACATGACAACGTCGCCATCGGCGTGTGCGTGCCGTTCCCATATCTCGCGCAGG
CGCAGGCTCAGCTTCAGGGCGGTCGCGTCTCGTGGGGCTCGCAGGACGTGTCCGCGCACGAGCAGGGCGCCTACACCGGC
GAAGTCGCGGCCGGCATGGTGGCGGAGTTCGGCGCGGCGTACGCGATCGTCGGGCACTCGGAGCGCCGCGCGTATCACGG
CGAATCGAACGAGACCGTCGCGGCGAAGGCGCGGCGCGCGCTCGCTGCGGGGTTGACGCCCATCGTGTGCGTCGGCGAGA
CGCTTGCCGAGCGCGAAGCGGGCACGACCGAGCAGGTGGTCGGCGCGCAGCTCGATGCGGTGCTCGCGGTGCTGTCGCCG
GACGAGGCGGCGCGCATCGTCGTCGCATACGAGCCCGTATGGGCCATCGGCACGGGCAAGAGCGCGACGGCCGAGCAGGC
GCAGCAGGTGCATGCGTTCCTGCGCGGACGGCTCGCGGCGAAGGGCGCCGGGCACGTGTCGCTGTTGTATGGCGGCAGCG
TGAAGGCCGACAACGCTGCCGAGCTGTTCGGCCAGCCGGACATCGACGGCGGCCTGATTGGCGGCGCGTCGTTGAAGAGC
GGGGATTTCCTGGCGATCTGCCGGGCAGCGAAGTAA

Upstream 100 bases:

>100_bases
GGTCGTTTGACCGGTTCTTGAGCGTCGCAGTAAAATCGCGGGTTCGCTTCGCCAGATGAACACGACGCCCGGCCTCGGCG
CGTCCATGACGAGACAAACG

Downstream 100 bases:

>100_bases
GCGTTCGCGAGACGCGTGTGAAGAATATCGGGGCGGCCGGCAGGTGCGCGGGCTGCTTGAAACCAAACAGGTGAATGTAT
GCCGTATCTGAAAGTCTTGA

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSKQRIKRVIGNWKMHGRLSGNQALLTEVAQGAQAVHDNVAIGVCVPFPYLAQAQAQLQGGRVSWGSQDVSAHEQGAYTG
EVAAGMVAEFGAAYAIVGHSERRAYHGESNETVAAKARRALAAGLTPIVCVGETLAEREAGTTEQVVGAQLDAVLAVLSP
DEAARIVVAYEPVWAIGTGKSATAEQAQQVHAFLRGRLAAKGAGHVSLLYGGSVKADNAAELFGQPDIDGGLIGGASLKS
GDFLAICRAAK

Sequences:

>Translated_251_residues
MSKQRIKRVIGNWKMHGRLSGNQALLTEVAQGAQAVHDNVAIGVCVPFPYLAQAQAQLQGGRVSWGSQDVSAHEQGAYTG
EVAAGMVAEFGAAYAIVGHSERRAYHGESNETVAAKARRALAAGLTPIVCVGETLAEREAGTTEQVVGAQLDAVLAVLSP
DEAARIVVAYEPVWAIGTGKSATAEQAQQVHAFLRGRLAAKGAGHVSLLYGGSVKADNAAELFGQPDIDGGLIGGASLKS
GDFLAICRAAK
>Mature_250_residues
SKQRIKRVIGNWKMHGRLSGNQALLTEVAQGAQAVHDNVAIGVCVPFPYLAQAQAQLQGGRVSWGSQDVSAHEQGAYTGE
VAAGMVAEFGAAYAIVGHSERRAYHGESNETVAAKARRALAAGLTPIVCVGETLAEREAGTTEQVVGAQLDAVLAVLSPD
EAARIVVAYEPVWAIGTGKSATAEQAQQVHAFLRGRLAAKGAGHVSLLYGGSVKADNAAELFGQPDIDGGLIGGASLKSG
DFLAICRAAK

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=253, Percent_Identity=41.501976284585, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI226529917, Length=255, Percent_Identity=41.1764705882353, Blast_Score=175, Evalue=4e-44,
Organism=Escherichia coli, GI1790353, Length=250, Percent_Identity=47.2, Blast_Score=214, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17536593, Length=246, Percent_Identity=45.5284552845528, Blast_Score=193, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6320255, Length=243, Percent_Identity=39.0946502057613, Blast_Score=172, Evalue=4e-44,
Organism=Drosophila melanogaster, GI28572004, Length=245, Percent_Identity=45.7142857142857, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28572008, Length=245, Percent_Identity=45.7142857142857, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28572006, Length=245, Percent_Identity=45.7142857142857, Blast_Score=185, Evalue=2e-47,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 25941; Mature: 25809

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQRIKRVIGNWKMHGRLSGNQALLTEVAQGAQAVHDNVAIGVCVPFPYLAQAQAQLQG
CCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
GRVSWGSQDVSAHEQGAYTGEVAAGMVAEFGAAYAIVGHSERRAYHGESNETVAAKARRA
CEECCCCCCCCHHHCCCCCHHHHHHHHHHHCCEEEEEECCHHHCCCCCCCCHHHHHHHHH
LAAGLTPIVCVGETLAEREAGTTEQVVGAQLDAVLAVLSPDEAARIVVAYEPVWAIGTGK
HHHCCCCEEECCHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCEEEEEEECCEEEEECCC
SATAEQAQQVHAFLRGRLAAKGAGHVSLLYGGSVKADNAAELFGQPDIDGGLIGGASLKS
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHCCCCCCCCCEECCCCCCC
GDFLAICRAAK
CCEEEEEECCC
>Mature Secondary Structure 
SKQRIKRVIGNWKMHGRLSGNQALLTEVAQGAQAVHDNVAIGVCVPFPYLAQAQAQLQG
CHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
GRVSWGSQDVSAHEQGAYTGEVAAGMVAEFGAAYAIVGHSERRAYHGESNETVAAKARRA
CEECCCCCCCCHHHCCCCCHHHHHHHHHHHCCEEEEEECCHHHCCCCCCCCHHHHHHHHH
LAAGLTPIVCVGETLAEREAGTTEQVVGAQLDAVLAVLSPDEAARIVVAYEPVWAIGTGK
HHHCCCCEEECCHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCEEEEEEECCEEEEECCC
SATAEQAQQVHAFLRGRLAAKGAGHVSLLYGGSVKADNAAELFGQPDIDGGLIGGASLKS
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHCCCCCCCCCEECCCCCCC
GDFLAICRAAK
CCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA