Click here to switch to the map view.

The map label for this gene is mas [H]

Identifier: 83720037

GI number: 83720037

Start: 1200939

End: 1201958

Strand: Direct

Name: mas [H]

Synonym: BTH_I1057

Alternate gene names: 83720037

Gene position: 1200939-1201958 (Clockwise)

Preceding gene: 83718859

Following gene: 83719537

Centisome position: 31.53

GC content: 68.53

Gene sequence:

>1020_bases
ATGAAAGCGATCGAAATCACCGAATTCGGCGCGCCTGACGTGCTGAAGCTGACGGAGCGGCCGCAGCCGGAGCCGAAGCG
CGGCGAGGTGCTGATCAAGGTGGCGGCGTCTGGCGTGAACCGCCCGGACGTGTTCCAGAGAAAGGGCGCTTACGCGCCGC
CTCCCGGCGCGTCGGATCTGCCTGGTCTCGAGGTGGCGGGCGAGATCGTCGGCGGCGATCTGTCCGATCCCGCGACGAAC
CCGTTCGGGCTGAAGGTGGGCGAGCGCGTCTGCGCGCTGCTCGCGGGCGGCGGCTACGCGCAATACGTCGCGGCGCCGCT
CGCGCAGTGCCTGCCGGTGCCGAAGGGGTTGACCGACGTCGAGGCCGCTTCGCTGCCCGAGACGTTCTTCACGGTCTGGA
GCAACGTGTTCGATCGCGCGCAACTGGGCGCGGGCGAAGGCGGCGCGCTGGAAACGTTCCTCGTGCAGGGCGGCTCGAGC
GGCATCGGCGTGACGGCGATCCAGATCGCGCATGCGCTCGGCTTTCGCGTGTTCGCGACCGCGGGCACCGACGATAAATG
CCGCGCTTGCGAAGCGCTCGGCGCGGAGCGCGCGATCAACTACAAGACCGAGGATTTCGTCGAGGTCGTGAAGTCGCTCA
CGCACGATCGCGGCGTCGACGTGATTCTCGACATGGTCGCGGGAGCGTACGTGGCGCGCGAGTTGACGGCGCTCGCGGAC
GGCGGGCGGCTTGTCGTGATCGCGCTCCTCGGCGGCGCGAAGTCGGAAATCAACGTGGCCGAGATCCTCCGGAGACGTCT
CACGATCACGGGCTCGACGCTGCGGCCGCGCCCCGTCGAATTCAAGGCGCGCATCGCCGCGCAACTGAAGGCGCGCGTGT
GGCCGCTCATCGAGGGCGGCCATGTGAAGCCCGTCGTCTATCGCGTGCTGCCGGCCGCACAGGCCGCCGATGCGCATGCG
CTGATGGAAAGCAGCGAACACGTCGGCAAGATCGTGCTGGATTGGGGTGCGAACGCTTGA

Upstream 100 bases:

>100_bases
CCGGCAGCGCGAACGCGCGCCGGCCGTTTTTCACAGGATGGGCCGGTTTGCGGGGCGCGCATCGCGCGCGCAAACCCGTC
ACGATCTTGGAGCGACGTGC

Downstream 100 bases:

>100_bases
CATCGGTCGTTTGACCGGTTCTTGAGCGTCGCAGTAAAATCGCGGGTTCGCTTCGCCAGATGAACACGACGCCCGGCCTC
GGCGCGTCCATGACGAGACA

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKAIEITEFGAPDVLKLTERPQPEPKRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDLPGLEVAGEIVGGDLSDPATN
PFGLKVGERVCALLAGGGYAQYVAAPLAQCLPVPKGLTDVEAASLPETFFTVWSNVFDRAQLGAGEGGALETFLVQGGSS
GIGVTAIQIAHALGFRVFATAGTDDKCRACEALGAERAINYKTEDFVEVVKSLTHDRGVDVILDMVAGAYVARELTALAD
GGRLVVIALLGGAKSEINVAEILRRRLTITGSTLRPRPVEFKARIAAQLKARVWPLIEGGHVKPVVYRVLPAAQAADAHA
LMESSEHVGKIVLDWGANA

Sequences:

>Translated_339_residues
MKAIEITEFGAPDVLKLTERPQPEPKRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDLPGLEVAGEIVGGDLSDPATN
PFGLKVGERVCALLAGGGYAQYVAAPLAQCLPVPKGLTDVEAASLPETFFTVWSNVFDRAQLGAGEGGALETFLVQGGSS
GIGVTAIQIAHALGFRVFATAGTDDKCRACEALGAERAINYKTEDFVEVVKSLTHDRGVDVILDMVAGAYVARELTALAD
GGRLVVIALLGGAKSEINVAEILRRRLTITGSTLRPRPVEFKARIAAQLKARVWPLIEGGHVKPVVYRVLPAAQAADAHA
LMESSEHVGKIVLDWGANA
>Mature_339_residues
MKAIEITEFGAPDVLKLTERPQPEPKRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDLPGLEVAGEIVGGDLSDPATN
PFGLKVGERVCALLAGGGYAQYVAAPLAQCLPVPKGLTDVEAASLPETFFTVWSNVFDRAQLGAGEGGALETFLVQGGSS
GIGVTAIQIAHALGFRVFATAGTDDKCRACEALGAERAINYKTEDFVEVVKSLTHDRGVDVILDMVAGAYVARELTALAD
GGRLVVIALLGGAKSEINVAEILRRRLTITGSTLRPRPVEFKARIAAQLKARVWPLIEGGHVKPVVYRVLPAAQAADAHA
LMESSEHVGKIVLDWGANA

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=340, Percent_Identity=36.7647058823529, Blast_Score=208, Evalue=5e-54,
Organism=Homo sapiens, GI22538444, Length=340, Percent_Identity=36.7647058823529, Blast_Score=208, Evalue=5e-54,
Organism=Homo sapiens, GI194239674, Length=337, Percent_Identity=32.9376854599407, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI13236495, Length=337, Percent_Identity=32.9376854599407, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI194239676, Length=337, Percent_Identity=29.9703264094956, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI18379349, Length=352, Percent_Identity=27.5568181818182, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI24308257, Length=357, Percent_Identity=26.0504201680672, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI197927207, Length=184, Percent_Identity=31.5217391304348, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI28557745, Length=285, Percent_Identity=29.1228070175439, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41872631, Length=316, Percent_Identity=27.8481012658228, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI47519420, Length=357, Percent_Identity=24.9299719887955, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790485, Length=340, Percent_Identity=29.1176470588235, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17507255, Length=305, Percent_Identity=29.8360655737705, Blast_Score=105, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6319520, Length=342, Percent_Identity=26.9005847953216, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323961, Length=349, Percent_Identity=26.3610315186246, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=349, Percent_Identity=26.3610315186246, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=344, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221330659, Length=251, Percent_Identity=25.4980079681275, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920632, Length=251, Percent_Identity=25.4980079681275, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24581345, Length=251, Percent_Identity=25.0996015936255, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 35575; Mature: 35575

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIEITEFGAPDVLKLTERPQPEPKRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDL
CCCEEECCCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGEIVGGDLSDPATNPFGLKVGERVCALLAGGGYAQYVAAPLAQCLPVPKGLTDV
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
EAASLPETFFTVWSNVFDRAQLGAGEGGALETFLVQGGSSGIGVTAIQIAHALGFRVFAT
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCEEEEE
AGTDDKCRACEALGAERAINYKTEDFVEVVKSLTHDRGVDVILDMVAGAYVARELTALAD
CCCCHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
GGRLVVIALLGGAKSEINVAEILRRRLTITGSTLRPRPVEFKARIAAQLKARVWPLIEGG
CCCEEEEEEECCCCCCCCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHCCEECCC
HVKPVVYRVLPAAQAADAHALMESSEHVGKIVLDWGANA
CCCHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCC
>Mature Secondary Structure
MKAIEITEFGAPDVLKLTERPQPEPKRGEVLIKVAASGVNRPDVFQRKGAYAPPPGASDL
CCCEEECCCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGEIVGGDLSDPATNPFGLKVGERVCALLAGGGYAQYVAAPLAQCLPVPKGLTDV
CCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
EAASLPETFFTVWSNVFDRAQLGAGEGGALETFLVQGGSSGIGVTAIQIAHALGFRVFAT
HHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCEEEEE
AGTDDKCRACEALGAERAINYKTEDFVEVVKSLTHDRGVDVILDMVAGAYVARELTALAD
CCCCHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
GGRLVVIALLGGAKSEINVAEILRRRLTITGSTLRPRPVEFKARIAAQLKARVWPLIEGG
CCCEEEEEEECCCCCCCCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHCCEECCC
HVKPVVYRVLPAAQAADAHALMESSEHVGKIVLDWGANA
CCCHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]