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The map label for this gene is nudL [H]

Identifier: 83719482

GI number: 83719482

Start: 1874383

End: 1875426

Strand: Direct

Name: nudL [H]

Synonym: BTH_I1665

Alternate gene names: 83719482

Gene position: 1874383-1875426 (Clockwise)

Preceding gene: 83719331

Following gene: 83718751

Centisome position: 49.21

GC content: 68.2

Gene sequence:

>1044_bases
ATGGGGCGTCGGCCGCTCGCCGCAAATTCGAGCCACGGTCGACATTTCGGTCGTGTCTGCGCCGCCGCGCCCCAGTCCCC
GATCTCGCCCCGAGCCGCCGCCCGCAGCAAATCGCCGAATCCGGCCAATTGCATTTCGCGCGATGTTGTGCGTGACGGCT
TGCATGCATTCGACCGGCGAGCCACTGCCGATATCGCGCTCGCCCCTCTCGCAACGCATCCAGGCCGACGAGCGTGCCGG
AGCGAACACGTAAAATGCTGCGGTCCCCGGCGGCGGGGCCGTCCGGCGAGCGGCCCCGGCGGGCGTTTTTTTCTTTTCGG
CGCGACAATATGGCCATATCCATTCCGAGCAGAGCGACCCTTGACCCGCCGCCCCATCATCGACCCTGAAGTGCTGCCGA
TCGAGACGACCGGCGCTGGCCTGGCTCCTGTCCCGCCGTCGTTGCTGACGCCGGACGGGCTGCGCGATCGTTTCGCGCAG
CCGCCCGTATGGACTCAGGAGCCCGCCGAGGCACAACTTGCCGACGGCATCGATCCGCGCAGCGCGGCCGTGCTCGTGCC
GCTCGTCGTGCGCGAGCGCGGCCTGACGGTCCTGCTCACGCAGCGTGCGGACCACCTGAACGACCATGCCGGCCAGGTCA
GCTTTCCGGGCGGACGCCGCGAGCCCGACGACCGCGACGCGAACGCCACTGCGCTGCGCGAGGCGCGCGAGGAGATCGCG
CTTTCGCACGAGCGCGTCGAATTGCTCGGCGCGCTGCCCGACTATCTGACGGGCACGGGCTTTTGCGTGACGCCTGTCGT
GGCGCTTGTCCATCCGCCATTTACGGTGGAGGCGGATACGCTCGAAGTGGCCGAGATCTTCGAGGTGCCGTTCGATTTCC
TGATGAACCCCGCCCATCATCAGGTGAGGGTGTTCCGCTGGGAGGGCGGCGAGCGGCGTTTCTTCGCGATGCCGTATCCG
CGCGGACCGGTCGGCGGCCAGTATTTCATCTGGGGCGCGACGGCCGGCATGCTGCGCAACCTGTATCGCTTTCTCGCGGC
CTAG

Upstream 100 bases:

>100_bases
GACCTGTGCTGCTCCAGTGAGTCGTTGCAACCGGAGAACGGGTGATTCAAACGGCATGACGCATCGTCCGATGCGCGAGG
GGCCACGCGTGAATGCCCAA

Downstream 100 bases:

>100_bases
TGGCGGGCGCCACAGTCGGCGCAAGCCGGAGCCATCCGGCGCGCCCGCTGTGCTATCTTTACGCGAAAAATCAATCATCC
CAGAACGGCACGGCCCTTCG

Product: MutT/NUDIX NTP pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MGRRPLAANSSHGRHFGRVCAAAPQSPISPRAAARSKSPNPANCISRDVVRDGLHAFDRRATADIALAPLATHPGRRACR
SEHVKCCGPRRRGRPASGPGGRFFLFGATIWPYPFRAERPLTRRPIIDPEVLPIETTGAGLAPVPPSLLTPDGLRDRFAQ
PPVWTQEPAEAQLADGIDPRSAAVLVPLVVRERGLTVLLTQRADHLNDHAGQVSFPGGRREPDDRDANATALREAREEIA
LSHERVELLGALPDYLTGTGFCVTPVVALVHPPFTVEADTLEVAEIFEVPFDFLMNPAHHQVRVFRWEGGERRFFAMPYP
RGPVGGQYFIWGATAGMLRNLYRFLAA

Sequences:

>Translated_347_residues
MGRRPLAANSSHGRHFGRVCAAAPQSPISPRAAARSKSPNPANCISRDVVRDGLHAFDRRATADIALAPLATHPGRRACR
SEHVKCCGPRRRGRPASGPGGRFFLFGATIWPYPFRAERPLTRRPIIDPEVLPIETTGAGLAPVPPSLLTPDGLRDRFAQ
PPVWTQEPAEAQLADGIDPRSAAVLVPLVVRERGLTVLLTQRADHLNDHAGQVSFPGGRREPDDRDANATALREAREEIA
LSHERVELLGALPDYLTGTGFCVTPVVALVHPPFTVEADTLEVAEIFEVPFDFLMNPAHHQVRVFRWEGGERRFFAMPYP
RGPVGGQYFIWGATAGMLRNLYRFLAA
>Mature_346_residues
GRRPLAANSSHGRHFGRVCAAAPQSPISPRAAARSKSPNPANCISRDVVRDGLHAFDRRATADIALAPLATHPGRRACRS
EHVKCCGPRRRGRPASGPGGRFFLFGATIWPYPFRAERPLTRRPIIDPEVLPIETTGAGLAPVPPSLLTPDGLRDRFAQP
PVWTQEPAEAQLADGIDPRSAAVLVPLVVRERGLTVLLTQRADHLNDHAGQVSFPGGRREPDDRDANATALREAREEIAL
SHERVELLGALPDYLTGTGFCVTPVVALVHPPFTVEADTLEVAEIFEVPFDFLMNPAHHQVRVFRWEGGERRFFAMPYPR
GPVGGQYFIWGATAGMLRNLYRFLAA

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=155, Percent_Identity=36.1290322580645, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1788115, Length=169, Percent_Identity=42.0118343195266, Blast_Score=92, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17536993, Length=120, Percent_Identity=39.1666666666667, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI18859683, Length=171, Percent_Identity=35.672514619883, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 38019; Mature: 37888

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRRPLAANSSHGRHFGRVCAAAPQSPISPRAAARSKSPNPANCISRDVVRDGLHAFDRR
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ATADIALAPLATHPGRRACRSEHVKCCGPRRRGRPASGPGGRFFLFGATIWPYPFRAERP
CCCCEEEECCCCCCCHHHHHHCCHHHCCCCCCCCCCCCCCCEEEEECCEECCCCCCCCCC
LTRRPIIDPEVLPIETTGAGLAPVPPSLLTPDGLRDRFAQPPVWTQEPAEAQLADGIDPR
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHCCCCCC
SAAVLVPLVVRERGLTVLLTQRADHLNDHAGQVSFPGGRREPDDRDANATALREAREEIA
CCEEEEHHHHHCCCCEEEEECCCHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LSHERVELLGALPDYLTGTGFCVTPVVALVHPPFTVEADTLEVAEIFEVPFDFLMNPAHH
HHHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHCCHHHHCCCCCC
QVRVFRWEGGERRFFAMPYPRGPVGGQYFIWGATAGMLRNLYRFLAA
EEEEEEEECCCEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure 
GRRPLAANSSHGRHFGRVCAAAPQSPISPRAAARSKSPNPANCISRDVVRDGLHAFDRR
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ATADIALAPLATHPGRRACRSEHVKCCGPRRRGRPASGPGGRFFLFGATIWPYPFRAERP
CCCCEEEECCCCCCCHHHHHHCCHHHCCCCCCCCCCCCCCCEEEEECCEECCCCCCCCCC
LTRRPIIDPEVLPIETTGAGLAPVPPSLLTPDGLRDRFAQPPVWTQEPAEAQLADGIDPR
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHCCCCCC
SAAVLVPLVVRERGLTVLLTQRADHLNDHAGQVSFPGGRREPDDRDANATALREAREEIA
CCEEEEHHHHHCCCCEEEEECCCHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LSHERVELLGALPDYLTGTGFCVTPVVALVHPPFTVEADTLEVAEIFEVPFDFLMNPAHH
HHHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHCCHHHHCCCCCC
QVRVFRWEGGERRFFAMPYPRGPVGGQYFIWGATAGMLRNLYRFLAA
EEEEEEEECCCEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]