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The map label for this gene is ftsW [H]

Identifier: 83719280

GI number: 83719280

Start: 1261495

End: 1262883

Strand: Direct

Name: ftsW [H]

Synonym: BTH_I1117

Alternate gene names: 83719280

Gene position: 1261495-1262883 (Clockwise)

Preceding gene: 83720203

Following gene: 83719178

Centisome position: 33.12

GC content: 65.95

Gene sequence:

>1389_bases
ATGCGCGAGCCTCGACATGTTCCGCAATTACGCGCATCGGGCCGACGTTTTCCGCAGCGCGGTCGAAGACATCGCTTTGG
AAAAAGGAACGACGCTATGAGCTGGTCCGATCGCCTCGTTTCCCGTTTCAATGGCGCCCGTGACGCGGGAGGCGGCGCCG
CGCCGCGCACCGCCGCGCGGGCGGCCTCGGGCGCGCGCGCCGCGGCGGGCGGCCTCGCGAGCGTCGTCAACGGCGCGCGT
CCTACCCGTTCGCGGATGCTCGACTTCGACTACTCGCTGCTGTGGGTGTCGATCGCGCTCCTCGGGCTTGGCGTCGTGAT
GGTGTACTCGGCGTCGATCGCGATGCCGGATTCGCCGAAGTACGCGTCGTATCACGACTACGCATTCCTGCTGCGCCACT
GCGTGTCGCTCGTCGTGGCGTTCGTCGCGGCGGTGATCGCGTTCCGCGTGCCGGTATCGACGTGGGACAAGTACGCGCCG
CATCTCTTCCTGATCGCGCTCGTCGGCCTCGTGATCGTGCTGATTCCGCACATCGGCAAGGGCGTGAACGGCGCGCGCCG
CTGGATTCCGCTCGGCATCACGAACATGCAGCCGTCGGAAATCATGAAGCTCGCGGTGACGATCTACGCGGCGAACTACA
CGGTGCGCAAGCAGGAGTACATGCAGAGCTTCGCGAAGGGCTTCCTGCCGATGGCGTTCGCGGTCGGCCTCGTCGGCGCG
CTGCTGCTGCTCGAGCCGGACATGGGCGCGTTCATGGTGGTCGCCGCGATCGCGATGGGCGTGCTGTTCCTGGGCGGCGT
GAACGGCAAGCTGTTCGGCGGCCTCGTCGCGACGGCGGTGGGTACGTTCACGATGCTCGTCTGGTTGTCGCCGTGGCGCC
GCGAGCGGATCTTCGCGTACCTCGATCCGTGGGACGAACGCTACGCGCAGGGCAAGGCCTACCAGCTCACGCACTCGCTG
ATCGCGTTCGGGCGCGGCGAATGGTTCGGCGTCGGTCTGGGCGGCAGTGTCGAAAAGCTCAACTACCTGCCGGAAGCGCA
TACCGACTTCATTCTCGCGGTGATCGGCGAAGAGCTTGGCTTTGTCGGCGTGCTGGTCGTGATCCTGCTGTTCTACTGGA
TCGTGCGCCGCTCGTTCGAGATCGGCCGTCAGGCGCTCGCGCTCGATCGTACGTTCGCGGGGCTGATGGCGAAGGGCGTC
GGCATCTGGTTCGGCGCGCAGGCGTTCATCAACATGGGCGTGAACCTCGGCCTTCTGCCGACCAAGGGTCTCACGCTGCC
GCTCGTGAGCTACGGCGGGTCCGGCATCCTGCTGAACTGCATCTCGCTCGCGGTGCTGCTGCGCGTCGATTATGAGAATC
GTGTGTTGATGCGGGGAGGGAAGGTATGA

Upstream 100 bases:

>100_bases
ACACGGGCGTGCCGCTCGCCGATCACGCGACGCTCGAAAGCGCGGTGCGCGCGGCGGGCGCGCTCGCGCAGCCGGGCGAT
GCGGTGCTGCTGTCGCCCGC

Downstream 100 bases:

>100_bases
CCTCGACGCCGCGCACACTGATGGTGATGGCGGGCGGCACCGGGGGGCACGTGTTCCCCGGGCTCGCGGTCGCGCACCGG
ATGCAGGCGCAGGGCTGGCG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MREPRHVPQLRASGRRFPQRGRRHRFGKRNDAMSWSDRLVSRFNGARDAGGGAAPRTAARAASGARAAAGGLASVVNGAR
PTRSRMLDFDYSLLWVSIALLGLGVVMVYSASIAMPDSPKYASYHDYAFLLRHCVSLVVAFVAAVIAFRVPVSTWDKYAP
HLFLIALVGLVIVLIPHIGKGVNGARRWIPLGITNMQPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMAFAVGLVGA
LLLLEPDMGAFMVVAAIAMGVLFLGGVNGKLFGGLVATAVGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSL
IAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVIGEELGFVGVLVVILLFYWIVRRSFEIGRQALALDRTFAGLMAKGV
GIWFGAQAFINMGVNLGLLPTKGLTLPLVSYGGSGILLNCISLAVLLRVDYENRVLMRGGKV

Sequences:

>Translated_462_residues
MREPRHVPQLRASGRRFPQRGRRHRFGKRNDAMSWSDRLVSRFNGARDAGGGAAPRTAARAASGARAAAGGLASVVNGAR
PTRSRMLDFDYSLLWVSIALLGLGVVMVYSASIAMPDSPKYASYHDYAFLLRHCVSLVVAFVAAVIAFRVPVSTWDKYAP
HLFLIALVGLVIVLIPHIGKGVNGARRWIPLGITNMQPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMAFAVGLVGA
LLLLEPDMGAFMVVAAIAMGVLFLGGVNGKLFGGLVATAVGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSL
IAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVIGEELGFVGVLVVILLFYWIVRRSFEIGRQALALDRTFAGLMAKGV
GIWFGAQAFINMGVNLGLLPTKGLTLPLVSYGGSGILLNCISLAVLLRVDYENRVLMRGGKV
>Mature_462_residues
MREPRHVPQLRASGRRFPQRGRRHRFGKRNDAMSWSDRLVSRFNGARDAGGGAAPRTAARAASGARAAAGGLASVVNGAR
PTRSRMLDFDYSLLWVSIALLGLGVVMVYSASIAMPDSPKYASYHDYAFLLRHCVSLVVAFVAAVIAFRVPVSTWDKYAP
HLFLIALVGLVIVLIPHIGKGVNGARRWIPLGITNMQPSEIMKLAVTIYAANYTVRKQEYMQSFAKGFLPMAFAVGLVGA
LLLLEPDMGAFMVVAAIAMGVLFLGGVNGKLFGGLVATAVGTFTMLVWLSPWRRERIFAYLDPWDERYAQGKAYQLTHSL
IAFGRGEWFGVGLGGSVEKLNYLPEAHTDFILAVIGEELGFVGVLVVILLFYWIVRRSFEIGRQALALDRTFAGLMAKGV
GIWFGAQAFINMGVNLGLLPTKGLTLPLVSYGGSGILLNCISLAVLLRVDYENRVLMRGGKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=381, Percent_Identity=41.994750656168, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1786853, Length=343, Percent_Identity=32.3615160349854, Blast_Score=142, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 50344; Mature: 50344

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCEEEHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure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CCCCEEEHHHCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]